Danio rerio

58 known processes

nlk2

nemo like kinase, type 2

(Aliases: nlka)

nlk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound metabolic process GO:0006807 319 0.046
larval development GO:0002164 2 0.044
sensory organ development GO:0007423 393 0.039
cell surface receptor signaling pathway GO:0007166 325 0.038
blood vessel development GO:0001568 246 0.036
cellular macromolecule metabolic process GO:0044260 391 0.035
vasculature development GO:0001944 278 0.034
stem cell maintenance GO:0019827 4 0.034
cell projection morphogenesis GO:0048858 244 0.032
phagocytosis GO:0006909 3 0.031
embryonic organ development GO:0048568 381 0.030
blood vessel morphogenesis GO:0048514 216 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.030
multicellular organism growth GO:0035264 4 0.029
cellular amine metabolic process GO:0044106 2 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
response to chemical GO:0042221 320 0.028
nucleic acid metabolic process GO:0090304 244 0.028
aging GO:0007568 2 0.028
amine metabolic process GO:0009308 2 0.028
signal transduction GO:0007165 455 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.027
meiotic nuclear division GO:0007126 4 0.027
internal protein amino acid acetylation GO:0006475 2 0.027
stem cell proliferation GO:0072089 4 0.026
organic substance biosynthetic process GO:1901576 289 0.026
regulation of response to stimulus GO:0048583 269 0.026
neuron differentiation GO:0030182 353 0.026
cell morphogenesis GO:0000902 289 0.025
maintenance of location GO:0051235 4 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
positive regulation of transport GO:0051050 2 0.025
generation of neurons GO:0048699 385 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.024
neuron development GO:0048666 262 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
cell part morphogenesis GO:0032990 246 0.024
lipid storage GO:0019915 1 0.024
cellular component morphogenesis GO:0032989 336 0.024
biosynthetic process GO:0009058 294 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of synapse assembly GO:0051963 3 0.024
heterocycle metabolic process GO:0046483 290 0.024
cell projection organization GO:0030030 284 0.023
central nervous system development GO:0007417 387 0.023
gene expression GO:0010467 252 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
regulation of cytokine production GO:0001817 3 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
response to external stimulus GO:0009605 264 0.022
eye development GO:0001654 277 0.022
positive regulation of cell cycle GO:0045787 3 0.021
neuroblast proliferation GO:0007405 2 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cellular component movement GO:0006928 335 0.021
rna metabolic process GO:0016070 219 0.021
protein localization to nucleus GO:0034504 3 0.021
transcription dna templated GO:0006351 181 0.021
regulation of transcription dna templated GO:0006355 213 0.021
regionalization GO:0003002 274 0.021
axonogenesis GO:0007409 152 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
response to carbohydrate GO:0009743 3 0.020
regulation of primary metabolic process GO:0080090 311 0.020
regulation of protein catabolic process GO:0042176 1 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
regulation of biological quality GO:0065008 263 0.020
chordate embryonic development GO:0043009 271 0.020
nuclear transport GO:0051169 4 0.020
internal peptidyl lysine acetylation GO:0018393 2 0.020
head development GO:0060322 303 0.020
protein import GO:0017038 3 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of rna metabolic process GO:0051252 224 0.019
regulation of signal transduction GO:0009966 225 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of metabolic process GO:0019222 359 0.019
nucleic acid templated transcription GO:0097659 181 0.019
protein acetylation GO:0006473 2 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
cellular biosynthetic process GO:0044249 286 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
locomotion GO:0040011 313 0.019
cognition GO:0050890 1 0.019
negative regulation of biological process GO:0048519 304 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
regulation of protein transport GO:0051223 3 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
cellular protein catabolic process GO:0044257 4 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
neuron projection morphogenesis GO:0048812 161 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
sensory organ morphogenesis GO:0090596 200 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of protein targeting GO:1903533 2 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
negative regulation of dna metabolic process GO:0051053 4 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
negative regulation of cellular process GO:0048523 283 0.018
mitochondrion organization GO:0007005 4 0.018
tube morphogenesis GO:0035239 349 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
protein acylation GO:0043543 3 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
rna biosynthetic process GO:0032774 181 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of binding GO:0051098 3 0.017
heart development GO:0007507 313 0.017
organic acid metabolic process GO:0006082 31 0.017
chemosensory behavior GO:0007635 1 0.017
protein targeting to nucleus GO:0044744 3 0.017
response to hexose GO:0009746 3 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
protein import into nucleus GO:0006606 3 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
nuclear import GO:0051170 3 0.017
autophagy GO:0006914 4 0.017
single organism metabolic process GO:0044710 217 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
response to drug GO:0042493 3 0.017
regulation of reproductive process GO:2000241 4 0.016
digestive system development GO:0055123 289 0.016
ear development GO:0043583 127 0.016
organelle organization GO:0006996 227 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of gene expression GO:0010468 265 0.016
neuronal action potential GO:0019228 18 0.016
single organism organelle organization GO:1902589 199 0.016
stem cell division GO:0017145 1 0.016
regulation of cell activation GO:0050865 1 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
immune system process GO:0002376 241 0.016
angiogenesis GO:0001525 158 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of protein complex assembly GO:0043254 3 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
mononuclear cell proliferation GO:0032943 1 0.016
single organism nuclear import GO:1902593 3 0.016
gtp metabolic process GO:0046039 4 0.016
axon development GO:0061564 166 0.016
positive regulation of cellular process GO:0048522 201 0.016
gtp catabolic process GO:0006184 2 0.016
cell substrate adhesion GO:0031589 4 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
female sex differentiation GO:0046660 4 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
adult behavior GO:0030534 2 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
cellular response to nutrient levels GO:0031669 2 0.016
system process GO:0003008 185 0.016
cellular ketone metabolic process GO:0042180 11 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
leukocyte proliferation GO:0070661 1 0.015
lateral inhibition GO:0046331 1 0.015
embryonic skeletal system development GO:0048706 97 0.015
cellular component disassembly GO:0022411 1 0.015
somatic muscle development GO:0007525 4 0.015
transmission of nerve impulse GO:0019226 19 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
protein homooligomerization GO:0051260 3 0.015
peptide transport GO:0015833 1 0.015
olfactory lobe development GO:0021988 4 0.015
cell matrix adhesion GO:0007160 4 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
locomotor rhythm GO:0045475 3 0.015
exocytosis GO:0006887 1 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
cellular response to starvation GO:0009267 1 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
cell motility GO:0048870 244 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
female gonad development GO:0008585 4 0.015
positive regulation of secretion GO:0051047 1 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
determination of left right symmetry GO:0007368 179 0.014
regulation of transporter activity GO:0032409 2 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
cellular amide metabolic process GO:0043603 4 0.014
negative regulation of catabolic process GO:0009895 3 0.014
compound eye development GO:0048749 2 0.014
response to monosaccharide GO:0034284 3 0.014
specification of symmetry GO:0009799 204 0.014
immune system development GO:0002520 191 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
peptidyl serine modification GO:0018209 2 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
anterior posterior pattern specification GO:0009952 152 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
regulation of signaling GO:0023051 235 0.014
multicellular organismal signaling GO:0035637 22 0.014
regulation of mrna processing GO:0050684 3 0.014
hemopoiesis GO:0030097 183 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
brain development GO:0007420 293 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
camera type eye development GO:0043010 222 0.014
positive regulation of cytokine production GO:0001819 2 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
establishment of localization GO:0051234 244 0.014
hormone secretion GO:0046879 2 0.013
regulation of metal ion transport GO:0010959 4 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
positive regulation of immune effector process GO:0002699 3 0.013
lymphocyte proliferation GO:0046651 1 0.013
wnt signaling pathway GO:0016055 80 0.013
regulation of dna replication GO:0006275 3 0.013
neuron projection development GO:0031175 180 0.013
phagocytosis engulfment GO:0006911 1 0.013
positive regulation of biological process GO:0048518 253 0.013
protein metabolic process GO:0019538 183 0.013
small molecule metabolic process GO:0044281 77 0.013
secondary metabolic process GO:0019748 3 0.013
adherens junction organization GO:0034332 4 0.013
regulation of cell communication GO:0010646 232 0.013
cellular protein metabolic process GO:0044267 129 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
cell migration GO:0016477 237 0.013
protein complex disassembly GO:0043241 1 0.013
protein heterooligomerization GO:0051291 1 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
eye morphogenesis GO:0048592 144 0.013
response to uv GO:0009411 3 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
synaptic vesicle transport GO:0048489 1 0.013
rna localization GO:0006403 4 0.013
amino acid transport GO:0006865 2 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
synaptic target recognition GO:0008039 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
germ line stem cell maintenance GO:0030718 2 0.013
regulation of developmental process GO:0050793 247 0.013
golgi vesicle transport GO:0048193 3 0.013
atp catabolic process GO:0006200 4 0.013
regulation of biosynthetic process GO:0009889 250 0.013
endosomal transport GO:0016197 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
signal transduction in absence of ligand GO:0038034 1 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
gastrulation GO:0007369 208 0.012
neurological system process GO:0050877 62 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
hatching GO:0035188 4 0.012
somatic stem cell maintenance GO:0035019 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
hormone transport GO:0009914 2 0.012
transport GO:0006810 220 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
cartilage development GO:0051216 96 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
single organism transport GO:0044765 206 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
regulation of cell differentiation GO:0045595 142 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
nephron tubule morphogenesis GO:0072078 1 0.012
synaptic vesicle localization GO:0097479 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
embryonic heart tube development GO:0035050 133 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
energy reserve metabolic process GO:0006112 2 0.012
meiotic cell cycle process GO:1903046 3 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
action potential GO:0001508 19 0.012
negative regulation of kinase activity GO:0033673 4 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
sleep GO:0030431 1 0.012
protein localization to plasma membrane GO:0072659 1 0.012
chemotaxis GO:0006935 104 0.012
regulation of protein binding GO:0043393 3 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of inflammatory response GO:0050727 2 0.012
muscle structure development GO:0061061 196 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of tube size GO:0035150 2 0.011
skeletal system development GO:0001501 181 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
negative regulation of reproductive process GO:2000242 3 0.011
cell substrate junction assembly GO:0007044 2 0.011
post embryonic organ development GO:0048569 4 0.011
fertilization GO:0009566 3 0.011
single fertilization GO:0007338 3 0.011
centrosome organization GO:0051297 1 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
response to stress GO:0006950 263 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
regulation of cell projection assembly GO:0060491 4 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
primary neural tube formation GO:0014020 1 0.011
membrane invagination GO:0010324 1 0.011
heart morphogenesis GO:0003007 156 0.011
regulation of blood pressure GO:0008217 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
olfactory bulb development GO:0021772 4 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
protein dephosphorylation GO:0006470 3 0.011
b cell activation GO:0042113 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
membrane fusion GO:0061025 2 0.011
tissue remodeling GO:0048771 4 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
cytokinesis GO:0000910 3 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
protein polymerization GO:0051258 4 0.011
positive regulation of cell activation GO:0050867 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
peptidyl threonine modification GO:0018210 1 0.011
actin filament polymerization GO:0030041 2 0.011
regulation of nervous system development GO:0051960 90 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
mesenchyme development GO:0060485 127 0.011
dicarboxylic acid transport GO:0006835 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
taxis GO:0042330 109 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
response to topologically incorrect protein GO:0035966 2 0.011
protein secretion GO:0009306 1 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
digestive tract development GO:0048565 265 0.011
single organism localization GO:1902578 225 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
positive regulation of epithelial cell differentiation GO:0030858 2 0.010
positive regulation of reproductive process GO:2000243 2 0.010
positive regulation of histone modification GO:0031058 1 0.010
response to alkaloid GO:0043279 2 0.010
negative regulation of protein transport GO:0051224 3 0.010
single organism membrane fusion GO:0044801 2 0.010
developmental growth GO:0048589 166 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
macroautophagy GO:0016236 1 0.010
protein stabilization GO:0050821 2 0.010
regulation of membrane potential GO:0042391 23 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
oocyte maturation GO:0001556 4 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
response to glucose GO:0009749 3 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
inner ear development GO:0048839 126 0.010
cellular component biogenesis GO:0044085 178 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
tube closure GO:0060606 1 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010

nlk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
musculoskeletal system disease DOID:17 0 0.020
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.013
cardiovascular system disease DOID:1287 0 0.013
disease of metabolism DOID:0014667 0 0.013
nervous system disease DOID:863 0 0.010