Danio rerio

62 known processes

nlk1

nemo like kinase, type 1

(Aliases: zgc:111875,nlk,nlkb)

nlk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biological process GO:0048519 304 0.089
aging GO:0007568 2 0.075
larval development GO:0002164 2 0.075
cellular macromolecule metabolic process GO:0044260 391 0.053
protein metabolic process GO:0019538 183 0.050
cell projection organization GO:0030030 284 0.046
regulation of signaling GO:0023051 235 0.045
cellular biosynthetic process GO:0044249 286 0.044
signal transduction GO:0007165 455 0.042
protein localization to nucleus GO:0034504 3 0.042
regulation of biological quality GO:0065008 263 0.042
regionalization GO:0003002 274 0.040
heterocycle metabolic process GO:0046483 290 0.040
regulation of cell communication GO:0010646 232 0.039
negative regulation of cellular process GO:0048523 283 0.039
sensory organ development GO:0007423 393 0.038
cellular component morphogenesis GO:0032989 336 0.038
stem cell proliferation GO:0072089 4 0.038
establishment of protein localization to organelle GO:0072594 4 0.037
multicellular organism growth GO:0035264 4 0.037
organic substance biosynthetic process GO:1901576 289 0.036
biosynthetic process GO:0009058 294 0.036
regulation of metabolic process GO:0019222 359 0.036
maintenance of location GO:0051235 4 0.036
regulation of neural precursor cell proliferation GO:2000177 3 0.035
nitrogen compound metabolic process GO:0006807 319 0.034
cell part morphogenesis GO:0032990 246 0.033
nuclear transport GO:0051169 4 0.033
nucleocytoplasmic transport GO:0006913 4 0.032
generation of neurons GO:0048699 385 0.032
cellular protein catabolic process GO:0044257 4 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
cell substrate adhesion GO:0031589 4 0.031
establishment of localization GO:0051234 244 0.031
response to chemical GO:0042221 320 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
cell projection morphogenesis GO:0048858 244 0.030
regulation of protein transport GO:0051223 3 0.030
stem cell maintenance GO:0019827 4 0.030
locomotion GO:0040011 313 0.029
head development GO:0060322 303 0.029
regulation of protein ubiquitination GO:0031396 3 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
regulation of signal transduction GO:0009966 225 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
regulation of primary metabolic process GO:0080090 311 0.028
single organism nuclear import GO:1902593 3 0.028
gene expression GO:0010467 252 0.028
proteasomal protein catabolic process GO:0010498 2 0.027
eye development GO:0001654 277 0.027
compound eye development GO:0048749 2 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
response to stress GO:0006950 263 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
nuclear import GO:0051170 3 0.026
positive regulation of transport GO:0051050 2 0.026
regulation of stem cell proliferation GO:0072091 2 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
protein targeting to nucleus GO:0044744 3 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.026
single organism metabolic process GO:0044710 217 0.025
positive regulation of catabolic process GO:0009896 4 0.025
modification dependent protein catabolic process GO:0019941 3 0.025
positive regulation of cell cycle GO:0045787 3 0.025
lipid storage GO:0019915 1 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
protein import GO:0017038 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
protein dephosphorylation GO:0006470 3 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
neuroblast proliferation GO:0007405 2 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
phagocytosis GO:0006909 3 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
regulation of response to stimulus GO:0048583 269 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
transcription dna templated GO:0006351 181 0.024
cellular response to external stimulus GO:0071496 2 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
regulation of protein catabolic process GO:0042176 1 0.023
cellular protein modification process GO:0006464 100 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
cell morphogenesis GO:0000902 289 0.023
cognition GO:0050890 1 0.023
brain development GO:0007420 293 0.023
cellular protein metabolic process GO:0044267 129 0.023
neuron projection development GO:0031175 180 0.023
protein import into nucleus GO:0006606 3 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
regulation of protein targeting GO:1903533 2 0.021
regulation of cytokine production GO:0001817 3 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
regulation of cell projection assembly GO:0060491 4 0.021
blood vessel development GO:0001568 246 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
positive regulation of cellular process GO:0048522 201 0.021
regulation of cell substrate adhesion GO:0010810 1 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
regulation of protein complex assembly GO:0043254 3 0.021
neuron development GO:0048666 262 0.020
regulation of reproductive process GO:2000241 4 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
muscle structure development GO:0061061 196 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
cell matrix adhesion GO:0007160 4 0.020
digestive system development GO:0055123 289 0.020
positive regulation of cytokine production GO:0001819 2 0.020
positive regulation of cytoskeleton organization GO:0051495 3 0.020
mitochondrion organization GO:0007005 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
protein modification process GO:0036211 100 0.020
cell projection assembly GO:0030031 64 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of cell activation GO:0050865 1 0.019
cellular component movement GO:0006928 335 0.019
anterior posterior pattern specification GO:0009952 152 0.019
golgi vesicle transport GO:0048193 3 0.019
macromolecule modification GO:0043412 111 0.019
tube morphogenesis GO:0035239 349 0.019
muscle cell development GO:0055001 115 0.019
nuclear migration GO:0007097 3 0.019
immune system process GO:0002376 241 0.019
embryonic organ development GO:0048568 381 0.019
cytokinesis GO:0000910 3 0.019
exocytosis GO:0006887 1 0.019
cell surface receptor signaling pathway GO:0007166 325 0.018
axonogenesis GO:0007409 152 0.018
camera type eye development GO:0043010 222 0.018
cellular component disassembly GO:0022411 1 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
nucleic acid metabolic process GO:0090304 244 0.018
regulation of gene expression GO:0010468 265 0.018
cellular amine metabolic process GO:0044106 2 0.018
striated muscle cell development GO:0055002 108 0.018
apoptotic process GO:0006915 116 0.018
membrane invagination GO:0010324 1 0.018
gastrulation GO:0007369 208 0.018
single fertilization GO:0007338 3 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
rna metabolic process GO:0016070 219 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
neuron differentiation GO:0030182 353 0.017
protein acylation GO:0043543 3 0.017
response to organic substance GO:0010033 153 0.017
single organism transport GO:0044765 206 0.017
response to biotic stimulus GO:0009607 97 0.017
peptide transport GO:0015833 1 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
regulation of synapse organization GO:0050807 3 0.017
protein complex disassembly GO:0043241 1 0.017
sensory organ morphogenesis GO:0090596 200 0.017
organelle organization GO:0006996 227 0.017
phagocytosis engulfment GO:0006911 1 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
protein polymerization GO:0051258 4 0.017
rna biosynthetic process GO:0032774 181 0.017
protein acetylation GO:0006473 2 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
regulation of dendrite development GO:0050773 3 0.016
oxoacid metabolic process GO:0043436 31 0.016
cellular response to nutrient levels GO:0031669 2 0.016
amine metabolic process GO:0009308 2 0.016
digestive tract development GO:0048565 265 0.016
lateral inhibition GO:0046331 1 0.016
negative regulation of protein transport GO:0051224 3 0.016
response to uv GO:0009411 3 0.016
regulation of circadian rhythm GO:0042752 4 0.016
developmental growth GO:0048589 166 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
heart development GO:0007507 313 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
peptidyl serine modification GO:0018209 2 0.016
organic acid metabolic process GO:0006082 31 0.016
segmentation GO:0035282 97 0.015
gtp catabolic process GO:0006184 2 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of binding GO:0051098 3 0.015
response to alkaloid GO:0043279 2 0.015
negative regulation of kinase activity GO:0033673 4 0.015
central nervous system development GO:0007417 387 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
chemosensory behavior GO:0007635 1 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
system process GO:0003008 185 0.015
response to external biotic stimulus GO:0043207 97 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of apoptotic process GO:0042981 98 0.015
startle response GO:0001964 4 0.015
chordate embryonic development GO:0043009 271 0.015
cellular response to starvation GO:0009267 1 0.015
monoamine transport GO:0015844 1 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
cellular ketone metabolic process GO:0042180 11 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
macromolecular complex disassembly GO:0032984 1 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
fertilization GO:0009566 3 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
regulation of biosynthetic process GO:0009889 250 0.015
axon development GO:0061564 166 0.015
positive regulation of secretion GO:0051047 1 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
peptidyl threonine phosphorylation GO:0018107 1 0.015
positive regulation of immune effector process GO:0002699 3 0.014
autophagy GO:0006914 4 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
neuron projection morphogenesis GO:0048812 161 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
antimicrobial humoral response GO:0019730 2 0.014
rna localization GO:0006403 4 0.014
female sex differentiation GO:0046660 4 0.014
nucleic acid templated transcription GO:0097659 181 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
germ line stem cell maintenance GO:0030718 2 0.014
cellular component assembly GO:0022607 170 0.014
negative regulation of catabolic process GO:0009895 3 0.014
digestive tract morphogenesis GO:0048546 231 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
regulation of rna metabolic process GO:0051252 224 0.014
cellular response to hypoxia GO:0071456 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
small molecule metabolic process GO:0044281 77 0.014
adherens junction organization GO:0034332 4 0.014
regulation of synapse assembly GO:0051963 3 0.014
somatic muscle development GO:0007525 4 0.014
negative regulation of intracellular protein transport GO:0090317 3 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
cellular component biogenesis GO:0044085 178 0.013
neurotransmitter transport GO:0006836 2 0.013
hormone secretion GO:0046879 2 0.013
mesenchyme development GO:0060485 127 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
growth GO:0040007 174 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
sensory perception of pain GO:0019233 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
intracellular signal transduction GO:0035556 85 0.013
protein stabilization GO:0050821 2 0.013
sleep GO:0030431 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
response to corticosteroid GO:0031960 1 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
muscle cell differentiation GO:0042692 139 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
tube closure GO:0060606 1 0.013
vasculature development GO:0001944 278 0.013
blood vessel morphogenesis GO:0048514 216 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
response to carbohydrate GO:0009743 3 0.013
single organism localization GO:1902578 225 0.013
meiotic nuclear division GO:0007126 4 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
response to external stimulus GO:0009605 264 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.012
cilium organization GO:0044782 71 0.012
determination of bilateral symmetry GO:0009855 204 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
retina development in camera type eye GO:0060041 146 0.012
regulation of cell death GO:0010941 103 0.012
peptidyl threonine modification GO:0018210 1 0.012
protein secretion GO:0009306 1 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
camera type eye morphogenesis GO:0048593 108 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
neurotransmitter secretion GO:0007269 2 0.012
positive regulation of cell activation GO:0050867 1 0.012
cell substrate junction assembly GO:0007044 2 0.012
transport GO:0006810 220 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
multi organism process GO:0051704 134 0.012
forebrain development GO:0030900 96 0.012
protein localization to plasma membrane GO:0072659 1 0.012
synaptic vesicle localization GO:0097479 1 0.012
regulation of autophagy GO:0010506 3 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
cellular response to oxygen levels GO:0071453 1 0.012
single organism organelle organization GO:1902589 199 0.012
cell motility GO:0048870 244 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
regulation of mrna processing GO:0050684 3 0.012
convergent extension GO:0060026 118 0.012
response to drug GO:0042493 3 0.012
neurological system process GO:0050877 62 0.012
regulation of metal ion transport GO:0010959 4 0.012
cell death GO:0008219 121 0.012
response to other organism GO:0051707 97 0.011
phosphorus metabolic process GO:0006793 109 0.011
specification of symmetry GO:0009799 204 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
regulation of programmed cell death GO:0043067 101 0.011
negative regulation of defense response GO:0031348 2 0.011
neuronal action potential GO:0019228 18 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
endosomal transport GO:0016197 2 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
pronephros development GO:0048793 69 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
embryonic skeletal system development GO:0048706 97 0.011
stem cell division GO:0017145 1 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
response to nutrient GO:0007584 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
transmission of nerve impulse GO:0019226 19 0.011
localization of cell GO:0051674 244 0.011
heart morphogenesis GO:0003007 156 0.011
striated muscle tissue development GO:0014706 110 0.011
regulation of cell differentiation GO:0045595 142 0.011
angiogenesis GO:0001525 158 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
multi organism cellular process GO:0044764 2 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
protein polyubiquitination GO:0000209 4 0.011
b cell activation GO:0042113 2 0.011
phosphorylation GO:0016310 69 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
primary neural tube formation GO:0014020 1 0.011
regulation of cell shape GO:0008360 1 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
hormone transport GO:0009914 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
cell migration GO:0016477 237 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
immune system development GO:0002520 191 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
death GO:0016265 121 0.011
response to glucocorticoid GO:0051384 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
synaptic vesicle transport GO:0048489 1 0.011
wound healing GO:0042060 90 0.010
eye morphogenesis GO:0048592 144 0.010
nuclear export GO:0051168 1 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
g2 m transition of mitotic cell cycle GO:0000086 4 0.010
developmental cell growth GO:0048588 52 0.010
gtp metabolic process GO:0046039 4 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
meiotic cell cycle process GO:1903046 3 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
cellular response to organic substance GO:0071310 105 0.010
determination of left right symmetry GO:0007368 179 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
diencephalon development GO:0021536 58 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
cilium morphogenesis GO:0060271 85 0.010
astrocyte differentiation GO:0048708 1 0.010
cilium assembly GO:0042384 58 0.010

nlk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012