Danio rerio

134 known processes

atp6v1e1b

ATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b

(Aliases: chunp6932,wu:fj35f08,atp6e,atp6v1e1,fj35f08)

atp6v1e1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
notochord cell vacuolation GO:0060036 7 0.951
notochord cell development GO:0060035 9 0.927
sensory organ development GO:0007423 393 0.923
larval development GO:0002164 2 0.908
Worm
establishment of rna localization GO:0051236 3 0.745
pigment granule organization GO:0048753 4 0.738
retinal pigment epithelium development GO:0003406 8 0.669
retina development in camera type eye GO:0060041 146 0.656
camera type eye development GO:0043010 222 0.573
cellular pigmentation GO:0033059 30 0.500
nucleic acid transport GO:0050657 2 0.450
hydrogen transport GO:0006818 7 0.436
pigmentation GO:0043473 85 0.379
rna transport GO:0050658 2 0.366
eye development GO:0001654 277 0.306
lysosomal transport GO:0007041 2 0.296
embryonic organ development GO:0048568 381 0.277
pigment cell differentiation GO:0050931 38 0.271
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.246
eye pigmentation GO:0048069 4 0.235
embryo development ending in birth or egg hatching GO:0009792 271 0.234
Worm
notochord cell differentiation GO:0060034 18 0.229
aging GO:0007568 2 0.188
transmembrane transport GO:0055085 120 0.188
inorganic ion transmembrane transport GO:0098660 57 0.186
ph reduction GO:0045851 1 0.185
regulation of signaling GO:0023051 235 0.180
regulation of transmembrane transport GO:0034762 18 0.161
inorganic cation transmembrane transport GO:0098662 50 0.155
defense response to gram positive bacterium GO:0050830 6 0.146
eye morphogenesis GO:0048592 144 0.143
organelle fusion GO:0048284 3 0.132
ganglioside metabolic process GO:0001573 3 0.127
signal transduction GO:0007165 455 0.126
autophagy GO:0006914 4 0.113
membrane invagination GO:0010324 1 0.112
response to copper ion GO:0046688 13 0.110
skin development GO:0043588 54 0.098
regulation of cell communication GO:0010646 232 0.090
multicellular organism growth GO:0035264 4 0.086
camera type eye morphogenesis GO:0048593 108 0.086
regulation of ph GO:0006885 3 0.086
morphogenesis of an epithelium GO:0002009 333 0.084
programmed cell death GO:0012501 119 0.083
swim bladder maturation GO:0048796 5 0.081
neuromast hair cell development GO:0035675 6 0.080
regulation of cytokine production GO:0001817 3 0.080
response to stress GO:0006950 263 0.080
response to external stimulus GO:0009605 264 0.079
cell surface receptor signaling pathway GO:0007166 325 0.078
regulation of multicellular organism growth GO:0040014 4 0.078
cellular amine metabolic process GO:0044106 2 0.074
posttranscriptional gene silencing GO:0016441 3 0.074
system process GO:0003008 185 0.074
monovalent inorganic cation transport GO:0015672 42 0.073
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.071
specification of symmetry GO:0009799 204 0.069
response to metal ion GO:0010038 34 0.068
regulation of establishment of protein localization GO:0070201 4 0.064
single organism transport GO:0044765 206 0.064
phagocytosis engulfment GO:0006911 1 0.063
melanosome organization GO:0032438 4 0.063
regulation of cellular amine metabolic process GO:0033238 0 0.061
tube morphogenesis GO:0035239 349 0.061
organonitrogen compound metabolic process GO:1901564 74 0.061
endosomal transport GO:0016197 2 0.060
transport GO:0006810 220 0.059
cellular nitrogen compound metabolic process GO:0034641 290 0.059
rna localization GO:0006403 4 0.054
oxoacid metabolic process GO:0043436 31 0.054
epithelial cell differentiation GO:0030855 116 0.054
multicellular organismal signaling GO:0035637 22 0.053
defense response to bacterium GO:0042742 22 0.053
endosome to lysosome transport GO:0008333 1 0.052
epidermal cell differentiation GO:0009913 36 0.052
locomotion GO:0040011 313 0.052
regulation of systemic arterial blood pressure GO:0003073 1 0.051
cellular response to nutrient levels GO:0031669 2 0.049
ribonucleoside monophosphate catabolic process GO:0009158 4 0.048
regulation of programmed cell death GO:0043067 101 0.047
cellular response to external stimulus GO:0071496 2 0.047
notochord development GO:0030903 54 0.046
regulation of response to stimulus GO:0048583 269 0.046
peripheral nervous system neuron differentiation GO:0048934 28 0.046
establishment of protein localization to vacuole GO:0072666 1 0.045
protein targeting to vacuole GO:0006623 1 0.045
positive regulation of jnk cascade GO:0046330 3 0.044
exocytosis GO:0006887 1 0.044
cell death GO:0008219 121 0.043
cellular protein catabolic process GO:0044257 4 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.043
regulation of cell death GO:0010941 103 0.043
maintenance of location GO:0051235 4 0.043
cation transport GO:0006812 81 0.043
sialylation GO:0097503 4 0.042
anterior posterior pattern specification GO:0009952 152 0.041
ion transmembrane transport GO:0034220 91 0.041
regulation of cellular ketone metabolic process GO:0010565 7 0.041
membrane fusion GO:0061025 2 0.040
reproduction GO:0000003 40 0.040
Worm
amine metabolic process GO:0009308 2 0.040
optokinetic behavior GO:0007634 9 0.040
eye photoreceptor cell differentiation GO:0001754 45 0.039
regulation of multicellular organismal process GO:0051239 277 0.039
cilium morphogenesis GO:0060271 85 0.038
head development GO:0060322 303 0.038
ear development GO:0043583 127 0.038
mechanoreceptor differentiation GO:0042490 37 0.038
regulation of blood pressure GO:0008217 1 0.038
protein n linked glycosylation GO:0006487 1 0.037
retina morphogenesis in camera type eye GO:0060042 79 0.037
regulation of cellular ph GO:0030641 1 0.036
single organism metabolic process GO:0044710 217 0.036
cation homeostasis GO:0055080 33 0.035
cellular response to starvation GO:0009267 1 0.034
regulation of intracellular ph GO:0051453 1 0.034
heart development GO:0007507 313 0.034
single organism localization GO:1902578 225 0.034
neuromast development GO:0048884 46 0.034
inner ear development GO:0048839 126 0.034
determination of bilateral symmetry GO:0009855 204 0.033
growth GO:0040007 174 0.033
regionalization GO:0003002 274 0.032
positive regulation of signal transduction GO:0009967 56 0.032
tissue remodeling GO:0048771 4 0.032
response to transition metal nanoparticle GO:1990267 28 0.031
axon ensheathment in central nervous system GO:0032291 2 0.031
synaptic vesicle transport GO:0048489 1 0.031
germ cell development GO:0007281 22 0.031
Worm
apoptotic process involved in development GO:1902742 2 0.030
inner ear morphogenesis GO:0042472 63 0.030
positive regulation of secretion GO:0051047 1 0.030
vacuole organization GO:0007033 9 0.030
cellular catabolic process GO:0044248 27 0.029
positive regulation of exocytosis GO:0045921 1 0.029
organelle membrane fusion GO:0090174 2 0.029
cellular response to biotic stimulus GO:0071216 3 0.029
urogenital system development GO:0001655 97 0.029
establishment of synaptic vesicle localization GO:0097480 1 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
autophagic vacuole fusion GO:0000046 1 0.028
regulation of erk1 and erk2 cascade GO:0070372 4 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.028
catabolic process GO:0009056 32 0.028
intrahepatic bile duct development GO:0035622 11 0.028
immune system development GO:0002520 191 0.028
heart contraction GO:0060047 71 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
regulation of biological quality GO:0065008 263 0.027
regulation of developmental process GO:0050793 247 0.027
negative regulation of metabolic process GO:0009892 86 0.027
epidermis development GO:0008544 48 0.026
centrosome duplication GO:0051298 1 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
swim bladder inflation GO:0048798 5 0.026
establishment of localization GO:0051234 244 0.026
vacuolar transport GO:0007034 2 0.026
nucleobase containing compound transport GO:0015931 2 0.026
gene silencing by rna GO:0031047 4 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
neural tube patterning GO:0021532 33 0.026
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.026
Worm
osteoclast development GO:0036035 1 0.026
microglia differentiation GO:0014004 1 0.025
death GO:0016265 121 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
cell proliferation involved in heart morphogenesis GO:0061323 2 0.025
regulation of cell shape GO:0008360 1 0.025
neuromast hair cell differentiation GO:0048886 12 0.025
cation transmembrane transport GO:0098655 65 0.025
positive regulation of striated muscle cell differentiation GO:0051155 1 0.025
ribosomal small subunit biogenesis GO:0042274 2 0.025
syncytium formation GO:0006949 12 0.025
cellular response to extracellular stimulus GO:0031668 2 0.024
negative regulation of biological process GO:0048519 304 0.024
gene expression GO:0010467 252 0.024
regulation of apoptotic process GO:0042981 98 0.023
protein metabolic process GO:0019538 183 0.023
vasculature development GO:0001944 278 0.023
notch signaling pathway GO:0007219 35 0.023
positive regulation of signaling GO:0023056 56 0.023
multi organism process GO:0051704 134 0.023
Worm
positive regulation of biological process GO:0048518 253 0.023
neural retina development GO:0003407 49 0.023
regulation of binding GO:0051098 3 0.023
pronuclear migration GO:0035046 1 0.023
embryonic organ morphogenesis GO:0048562 274 0.022
central nervous system development GO:0007417 387 0.022
single fertilization GO:0007338 3 0.022
regulation of signal transduction GO:0009966 225 0.022
respiratory electron transport chain GO:0022904 2 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.022
cellular amide metabolic process GO:0043603 4 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
erk1 and erk2 cascade GO:0070371 4 0.021
lateral line system development GO:0048925 76 0.021
positive regulation of cytokine production GO:0001819 2 0.021
regulation of membrane potential GO:0042391 23 0.021
secondary metabolic process GO:0019748 3 0.021
wnt signaling pathway GO:0016055 80 0.021
organelle localization GO:0051640 49 0.021
hydrogen ion transmembrane transport GO:1902600 6 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
centrosome cycle GO:0007098 1 0.020
determination of left right symmetry GO:0007368 179 0.020
intracellular transport GO:0046907 32 0.020
multicellular organismal reproductive process GO:0048609 35 0.020
Worm
p38mapk cascade GO:0038066 1 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
negative regulation of ras protein signal transduction GO:0046580 1 0.019
response to wounding GO:0009611 116 0.019
monovalent inorganic cation homeostasis GO:0055067 9 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
macromolecule localization GO:0033036 54 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
fertilization GO:0009566 3 0.019
neurotransmitter transport GO:0006836 2 0.018
positive regulation of neuron apoptotic process GO:0043525 1 0.018
neurological system process GO:0050877 62 0.018
positive regulation of transport GO:0051050 2 0.018
wound healing GO:0042060 90 0.018
blood circulation GO:0008015 87 0.018
regulation of ion transmembrane transport GO:0034765 18 0.018
organelle assembly GO:0070925 110 0.018
positive regulation of neuron death GO:1901216 1 0.018
response to amphetamine GO:0001975 1 0.018
cardiac muscle tissue development GO:0048738 48 0.017
oocyte anterior posterior axis specification GO:0007314 4 0.017
cell aging GO:0007569 2 0.017
spermatid development GO:0007286 2 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
rrna catabolic process GO:0016075 1 0.017
regulation of metal ion transport GO:0010959 4 0.016
heart looping GO:0001947 94 0.016
muscle structure development GO:0061061 196 0.016
vesicle mediated transport GO:0016192 22 0.016
Worm
regulation of protein catabolic process GO:0042176 1 0.016
regulation of cell activation GO:0050865 1 0.016
mechanosensory lateral line system development GO:0048881 49 0.016
embryonic heart tube morphogenesis GO:0003143 108 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
pole plasm assembly GO:0007315 4 0.016
spermatid differentiation GO:0048515 2 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
protein stabilization GO:0050821 2 0.016
single organism organelle organization GO:1902589 199 0.015
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.015
protein acylation GO:0043543 3 0.015
hair cell differentiation GO:0035315 32 0.015
removal of superoxide radicals GO:0019430 2 0.015
antimicrobial humoral response GO:0019730 2 0.015
developmental programmed cell death GO:0010623 4 0.015
regulation of establishment of planar polarity GO:0090175 4 0.015
monoamine transport GO:0015844 1 0.015
neuron differentiation GO:0030182 353 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
positive regulation of programmed cell death GO:0043068 29 0.015
lipid storage GO:0019915 1 0.014
microtubule based movement GO:0007018 33 0.014
cellular component assembly GO:0022607 170 0.014
female gamete generation GO:0007292 14 0.014
Worm
regulation of epithelial cell proliferation GO:0050678 3 0.014
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.014
heart morphogenesis GO:0003007 156 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.014
regulation of exocytosis GO:0017157 1 0.014
response to chemical GO:0042221 320 0.014
mononuclear cell proliferation GO:0032943 1 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
regulation of inflammatory response GO:0050727 2 0.013
melanocyte differentiation GO:0030318 26 0.013
sphingolipid biosynthetic process GO:0030148 2 0.013
hemopoiesis GO:0030097 183 0.013
regulation of organelle assembly GO:1902115 4 0.013
apoptotic process GO:0006915 116 0.013
negative regulation of signaling GO:0023057 96 0.013
telomere organization GO:0032200 1 0.013
single organism membrane fusion GO:0044801 2 0.013
developmental maturation GO:0021700 34 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
positive regulation of cell communication GO:0010647 56 0.013
nuclear transport GO:0051169 4 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
cellular response to stress GO:0033554 62 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
nucleocytoplasmic transport GO:0006913 4 0.012
peptide metabolic process GO:0006518 1 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
regulation of protein transport GO:0051223 3 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
nonmotile primary cilium assembly GO:0035058 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
positive regulation of catabolic process GO:0009896 4 0.012
sensory system development GO:0048880 76 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
cell morphogenesis GO:0000902 289 0.012
endodermal digestive tract morphogenesis GO:0061031 2 0.012
startle response GO:0001964 4 0.012
adherens junction maintenance GO:0034334 2 0.012
cellular component maintenance GO:0043954 3 0.012
posttranscriptional gene silencing by rna GO:0035194 3 0.012
pronephric duct development GO:0039022 13 0.012
single organism intracellular transport GO:1902582 25 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
superoxide metabolic process GO:0006801 2 0.012
renal system development GO:0072001 94 0.011
lytic vacuole organization GO:0080171 1 0.011
developmental pigmentation GO:0048066 48 0.011
immune system process GO:0002376 241 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
neuron development GO:0048666 262 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
oogenesis GO:0048477 14 0.011
Worm
regulation of cellular metabolic process GO:0031323 320 0.011
cellular localization GO:0051641 97 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of protein targeting GO:1903533 2 0.011
regulation of retina development in camera type eye GO:1902866 2 0.011
phagocytosis GO:0006909 3 0.011
myeloid cell development GO:0061515 32 0.011
developmental growth GO:0048589 166 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
negative regulation of signal transduction GO:0009968 94 0.011
chordate embryonic development GO:0043009 271 0.010
phosphatidylinositol biosynthetic process GO:0006661 1 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
action potential GO:0001508 19 0.010
regulation of tissue remodeling GO:0034103 2 0.010
regulation of reproductive process GO:2000241 4 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
anterior lateral line nerve glial cell development GO:0048939 3 0.010
oligodendrocyte differentiation GO:0048709 23 0.010
sexual reproduction GO:0019953 36 0.010
Worm

atp6v1e1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.067
lipid storage disease DOID:9455 0 0.067
lysosomal storage disease DOID:3211 0 0.067
inherited metabolic disorder DOID:655 0 0.067
disease of anatomical entity DOID:7 0 0.019
endocrine gland cancer DOID:170 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
immune system disease DOID:2914 0 0.010
nervous system disease DOID:863 0 0.010