Danio rerio

0 known processes

got2a

glutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2)

(Aliases: got2,zgc:66329)

got2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid catabolic process GO:0046395 3 0.448
Mouse
cellular respiration GO:0045333 3 0.223
very long chain fatty acid metabolic process GO:0000038 4 0.204
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.162
fatty acid beta oxidation GO:0006635 1 0.156
oxoacid metabolic process GO:0043436 31 0.151
Yeast Mouse Rat Fly
hydrogen peroxide metabolic process GO:0042743 2 0.123
fatty acid catabolic process GO:0009062 1 0.106
respiratory electron transport chain GO:0022904 2 0.097
small molecule catabolic process GO:0044282 3 0.086
Mouse
monocarboxylic acid catabolic process GO:0072329 3 0.080
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.075
regulation of biological quality GO:0065008 263 0.067
small molecule metabolic process GO:0044281 77 0.066
Yeast Mouse Rat Fly
organic acid catabolic process GO:0016054 3 0.064
Mouse
response to hydrogen peroxide GO:0042542 3 0.061
fatty acid oxidation GO:0019395 1 0.059
organelle organization GO:0006996 227 0.058
striated muscle cell development GO:0055002 108 0.054
cellular catabolic process GO:0044248 27 0.052
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.048
Yeast Mouse Rat Fly
regulation of cellular response to oxidative stress GO:1900407 2 0.048
signal transduction GO:0007165 455 0.047
organic acid metabolic process GO:0006082 31 0.045
Yeast Mouse Rat Fly
aging GO:0007568 2 0.044
Yeast
protein homooligomerization GO:0051260 3 0.043
cellular amino acid metabolic process GO:0006520 7 0.042
Yeast Mouse Rat Fly
carboxylic acid metabolic process GO:0019752 22 0.042
Yeast Mouse Rat Fly
regulation of primary metabolic process GO:0080090 311 0.042
mitochondrion organization GO:0007005 4 0.042
maintenance of location GO:0051235 4 0.042
electron transport chain GO:0022900 2 0.041
cellular response to reactive oxygen species GO:0034614 2 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.041
lipid oxidation GO:0034440 1 0.039
response to superoxide GO:0000303 2 0.037
reactive oxygen species metabolic process GO:0072593 6 0.035
hepaticobiliary system development GO:0061008 98 0.035
response to drug GO:0042493 3 0.034
heart development GO:0007507 313 0.034
cellular response to oxygen radical GO:0071450 2 0.032
cellular lipid catabolic process GO:0044242 3 0.032
striated muscle cell differentiation GO:0051146 129 0.030
regulation of metabolic process GO:0019222 359 0.029
cellular modified amino acid metabolic process GO:0006575 3 0.029
cell death in response to oxidative stress GO:0036473 2 0.029
positive regulation of biological process GO:0048518 253 0.028
cellular component movement GO:0006928 335 0.027
cellular response to superoxide GO:0071451 2 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
single organism metabolic process GO:0044710 217 0.027
Yeast Mouse Rat Fly
response to stress GO:0006950 263 0.026
muscle cell differentiation GO:0042692 139 0.026
reactive oxygen species biosynthetic process GO:1903409 1 0.026
macromolecular complex subunit organization GO:0043933 74 0.025
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
muscle structure development GO:0061061 196 0.024
lipid catabolic process GO:0016042 4 0.024
regulation of oxidative stress induced cell death GO:1903201 2 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
locomotion GO:0040011 313 0.024
larval development GO:0002164 2 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
organic substance biosynthetic process GO:1901576 289 0.022
Yeast Mouse Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.022
brain development GO:0007420 293 0.022
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.022
cellular response to hypoxia GO:0071456 1 0.022
regulation of rac protein signal transduction GO:0035020 1 0.022
generation of precursor metabolites and energy GO:0006091 5 0.022
cellular protein metabolic process GO:0044267 129 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
Yeast Mouse Rat Fly
estrogen metabolic process GO:0008210 2 0.021
regulation of protein catabolic process GO:0042176 1 0.021
heterocycle metabolic process GO:0046483 290 0.021
regulation of response to oxidative stress GO:1902882 2 0.020
response to chemical GO:0042221 320 0.020
regulation of tube size GO:0035150 2 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
regulation of blood vessel size GO:0050880 2 0.019
protein stabilization GO:0050821 2 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
Fly
cellular component morphogenesis GO:0032989 336 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
heart morphogenesis GO:0003007 156 0.018
single organism organelle organization GO:1902589 199 0.018
regulation of blood pressure GO:0008217 1 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
androgen metabolic process GO:0008209 2 0.017
cytoskeleton organization GO:0007010 96 0.017
cellular component assembly GO:0022607 170 0.017
Fly
negative regulation of intracellular transport GO:0032387 3 0.017
system process GO:0003008 185 0.017
alcohol biosynthetic process GO:0046165 2 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
secondary metabolic process GO:0019748 3 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
sensory organ morphogenesis GO:0090596 200 0.016
catabolic process GO:0009056 32 0.016
Mouse
sensory organ development GO:0007423 393 0.016
regulation of cell communication GO:0010646 232 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
response to transition metal nanoparticle GO:1990267 28 0.015
cellular ketone metabolic process GO:0042180 11 0.015
oxidation reduction process GO:0055114 41 0.015
regulation of cytokine production GO:0001817 3 0.015
gland development GO:0048732 143 0.015
negative regulation of kinase activity GO:0033673 4 0.015
regulation of muscle contraction GO:0006937 3 0.015
response to copper ion GO:0046688 13 0.015
circulatory system process GO:0003013 87 0.014
muscle cell development GO:0055001 115 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
iron ion homeostasis GO:0055072 4 0.014
cellular amide metabolic process GO:0043603 4 0.014
myotube differentiation GO:0014902 45 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
connective tissue development GO:0061448 99 0.014
response to cold GO:0009409 4 0.014
biosynthetic process GO:0009058 294 0.014
Yeast Mouse Fly
rna metabolic process GO:0016070 219 0.014
regulation of signal transduction GO:0009966 225 0.014
cardiac muscle tissue development GO:0048738 48 0.014
fatty acid biosynthetic process GO:0006633 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
negative regulation of cellular process GO:0048523 283 0.013
zymogen activation GO:0031638 3 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
carboxylic acid biosynthetic process GO:0046394 12 0.013
Yeast Mouse Fly
cellular response to oxidative stress GO:0034599 5 0.013
kidney epithelium development GO:0072073 23 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
nephron development GO:0072006 31 0.013
protein complex assembly GO:0006461 30 0.013
liver development GO:0001889 96 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
response to glucocorticoid GO:0051384 1 0.013
atp catabolic process GO:0006200 4 0.013
monocarboxylic acid biosynthetic process GO:0072330 12 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
immune system process GO:0002376 241 0.012
smooth muscle contraction GO:0006939 2 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
apoptotic process GO:0006915 116 0.012
cellular nitrogen compound metabolic process GO:0034641 290 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
regulation of gtpase activity GO:0043087 2 0.012
cell substrate adhesion GO:0031589 4 0.012
lateral inhibition GO:0046331 1 0.012
taxis GO:0042330 109 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
Yeast Mouse Rat Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
histone h3 k36 methylation GO:0010452 2 0.012
gene expression GO:0010467 252 0.012
striated muscle tissue development GO:0014706 110 0.012
regulation of signaling GO:0023051 235 0.012
regulation of protein transport GO:0051223 3 0.012
negative regulation of catabolic process GO:0009895 3 0.012
protein metabolic process GO:0019538 183 0.012
negative regulation of cell communication GO:0010648 96 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
response to external stimulus GO:0009605 264 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
homeostatic process GO:0042592 142 0.011
cellular response to oxygen levels GO:0071453 1 0.011
macromolecular complex assembly GO:0065003 35 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
inner ear receptor stereocilium organization GO:0060122 8 0.011
lipid homeostasis GO:0055088 3 0.011
axonogenesis GO:0007409 152 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
nitric oxide metabolic process GO:0046209 2 0.011
inner ear morphogenesis GO:0042472 63 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
neuron development GO:0048666 262 0.011
regulation of anatomical structure size GO:0090066 33 0.011
gtp catabolic process GO:0006184 2 0.010
branched chain amino acid metabolic process GO:0009081 1 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
regulation of nitrogen compound metabolic process GO:0051171 251 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of reproductive process GO:2000241 4 0.010
nephron epithelium development GO:0072009 16 0.010
gtp metabolic process GO:0046039 4 0.010
very long chain fatty acid biosynthetic process GO:0042761 4 0.010
macromolecule modification GO:0043412 111 0.010
dicarboxylic acid metabolic process GO:0043648 1 0.010
Yeast Mouse Rat Fly
cell motility GO:0048870 244 0.010
response to nutrient GO:0007584 3 0.010
neuron differentiation GO:0030182 353 0.010
cellular protein modification process GO:0006464 100 0.010
morphogenesis of an epithelium GO:0002009 333 0.010

got2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.048
inherited metabolic disorder DOID:655 0 0.048
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
motor neuron disease DOID:231 0 0.020
central nervous system disease DOID:331 0 0.020
amyotrophic lateral sclerosis DOID:332 0 0.020
neurodegenerative disease DOID:1289 0 0.020
mitochondrial metabolism disease DOID:700 0 0.013