Danio rerio

23 known processes

trim2a

tripartite motif-containing 2a

(Aliases: zgc:113099,MGC113099,trim2)

trim2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of ph GO:0006885 3 0.046
response to drug GO:0042493 3 0.046
regulation of cellular metabolic process GO:0031323 320 0.041
positive regulation of cell cycle GO:0045787 3 0.039
aging GO:0007568 2 0.038
sensory organ development GO:0007423 393 0.035
stem cell maintenance GO:0019827 4 0.034
maintenance of location GO:0051235 4 0.033
regulation of systemic arterial blood pressure GO:0003073 1 0.031
cellular response to molecule of bacterial origin GO:0071219 3 0.030
larval development GO:0002164 2 0.030
regulation of reactive oxygen species metabolic process GO:2000377 2 0.030
carbon dioxide transport GO:0015670 3 0.028
response to stress GO:0006950 263 0.027
cellular response to external stimulus GO:0071496 2 0.027
lipid storage GO:0019915 1 0.027
morphogenesis of an epithelium GO:0002009 333 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.026
polyol transport GO:0015791 7 0.025
immune system process GO:0002376 241 0.025
locomotion GO:0040011 313 0.025
signal transduction GO:0007165 455 0.024
vasculature development GO:0001944 278 0.024
amine metabolic process GO:0009308 2 0.024
cell migration GO:0016477 237 0.023
regulation of neural precursor cell proliferation GO:2000177 3 0.023
epidermal cell fate specification GO:0009957 4 0.023
cognition GO:0050890 1 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
exocytosis GO:0006887 1 0.023
carbohydrate homeostasis GO:0033500 1 0.022
regulation of cell communication GO:0010646 232 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
angiogenesis GO:0001525 158 0.022
regulation of blood pressure GO:0008217 1 0.021
regulation of protein complex assembly GO:0043254 3 0.021
response to external stimulus GO:0009605 264 0.021
cell motility GO:0048870 244 0.021
astrocyte differentiation GO:0048708 1 0.021
positive regulation of transport GO:0051050 2 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of biological quality GO:0065008 263 0.021
regulation of multicellular organism growth GO:0040014 4 0.020
homeostatic process GO:0042592 142 0.020
cellular component disassembly GO:0022411 1 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
gene expression GO:0010467 252 0.019
regulation of metabolic process GO:0019222 359 0.019
reactive oxygen species metabolic process GO:0072593 6 0.019
positive regulation of protein complex assembly GO:0031334 2 0.018
glucose homeostasis GO:0042593 1 0.018
peptide transport GO:0015833 1 0.018
stem cell proliferation GO:0072089 4 0.018
ameboidal type cell migration GO:0001667 143 0.018
sleep GO:0030431 1 0.018
immune system development GO:0002520 191 0.018
nephron epithelium morphogenesis GO:0072088 1 0.018
regulation of cell shape GO:0008360 1 0.018
auditory receptor cell fate determination GO:0042668 2 0.018
water transport GO:0006833 15 0.017
regulation of cytokine production GO:0001817 3 0.017
nephron tubule morphogenesis GO:0072078 1 0.017
localization of cell GO:0051674 244 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
positive regulation of catabolic process GO:0009896 4 0.017
protein polymerization GO:0051258 4 0.017
system process GO:0003008 185 0.017
inorganic anion transport GO:0015698 25 0.017
inner ear receptor cell fate commitment GO:0060120 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
regulation of hormone secretion GO:0046883 2 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
multicellular organism growth GO:0035264 4 0.016
blood vessel development GO:0001568 246 0.016
central nervous system development GO:0007417 387 0.016
nuclear import GO:0051170 3 0.016
compound eye development GO:0048749 2 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
regulation of signal transduction GO:0009966 225 0.016
positive regulation of cell division GO:0051781 2 0.016
interspecies interaction between organisms GO:0044419 4 0.016
negative regulation of catabolic process GO:0009895 3 0.015
heterocycle metabolic process GO:0046483 290 0.015
cellular response to reactive oxygen species GO:0034614 2 0.015
centrosome organization GO:0051297 1 0.015
cell projection organization GO:0030030 284 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
hormone secretion GO:0046879 2 0.015
head development GO:0060322 303 0.015
response to uv GO:0009411 3 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.015
protein complex disassembly GO:0043241 1 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
renal tubule morphogenesis GO:0061333 1 0.014
regulation of protein polymerization GO:0032271 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
mitochondrion organization GO:0007005 4 0.014
post embryonic organ development GO:0048569 4 0.014
actin filament polymerization GO:0030041 2 0.014
regulation of jak stat cascade GO:0046425 3 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of protein catabolic process GO:0042176 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
single organism nuclear import GO:1902593 3 0.014
action potential GO:0001508 19 0.014
positive regulation of secretion GO:0051047 1 0.014
brain development GO:0007420 293 0.014
cell projection morphogenesis GO:0048858 244 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
chordate embryonic development GO:0043009 271 0.014
wound healing GO:0042060 90 0.014
somatic muscle development GO:0007525 4 0.014
gtp catabolic process GO:0006184 2 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
protein metabolic process GO:0019538 183 0.014
phagocytosis engulfment GO:0006911 1 0.014
centrosome cycle GO:0007098 1 0.014
convergent extension GO:0060026 118 0.014
regulation of protein transport GO:0051223 3 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.013
tube closure GO:0060606 1 0.013
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
leukocyte proliferation GO:0070661 1 0.013
cartilage condensation GO:0001502 3 0.013
sensory organ morphogenesis GO:0090596 200 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
gtp metabolic process GO:0046039 4 0.013
membrane invagination GO:0010324 1 0.013
cellular component movement GO:0006928 335 0.013
lymphocyte proliferation GO:0046651 1 0.013
startle response GO:0001964 4 0.013
response to corticosteroid GO:0031960 1 0.013
rna localization GO:0006403 4 0.013
growth GO:0040007 174 0.013
porphyrin containing compound metabolic process GO:0006778 10 0.013
axonogenesis GO:0007409 152 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
tetrapyrrole biosynthetic process GO:0033014 8 0.013
regulation of protein targeting GO:1903533 2 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
atp catabolic process GO:0006200 4 0.013
phagocytosis GO:0006909 3 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
cellular amine metabolic process GO:0044106 2 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
protein targeting to nucleus GO:0044744 3 0.013
gas transport GO:0015669 3 0.013
hemopoiesis GO:0030097 183 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
endocrine hormone secretion GO:0060986 2 0.013
mononuclear cell proliferation GO:0032943 1 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
protein acylation GO:0043543 3 0.013
definitive hemopoiesis GO:0060216 18 0.013
protein localization to nucleus GO:0034504 3 0.012
toll like receptor signaling pathway GO:0002224 4 0.012
response to chemical GO:0042221 320 0.012
antimicrobial humoral response GO:0019730 2 0.012
cell morphogenesis GO:0000902 289 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
negative regulation of cytokine production GO:0001818 1 0.012
lateral inhibition GO:0046331 1 0.012
membrane fusion GO:0061025 2 0.012
anterior posterior pattern specification GO:0009952 152 0.012
response to biotic stimulus GO:0009607 97 0.012
auditory receptor cell fate commitment GO:0009912 4 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
intracellular signal transduction GO:0035556 85 0.012
macromolecular complex disassembly GO:0032984 1 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
hormone transport GO:0009914 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
nephron morphogenesis GO:0072028 2 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
cellular component morphogenesis GO:0032989 336 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
muscle structure development GO:0061061 196 0.012
biosynthetic process GO:0009058 294 0.012
negative regulation of muscle cell differentiation GO:0051148 1 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
cartilage development GO:0051216 96 0.012
meiotic nuclear division GO:0007126 4 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
erythrocyte differentiation GO:0030218 54 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
erythrocyte maturation GO:0043249 8 0.011
septum transversum development GO:0003343 4 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
generation of neurons GO:0048699 385 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
oxoacid metabolic process GO:0043436 31 0.011
regulation of synapse organization GO:0050807 3 0.011
protein import GO:0017038 3 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
regulation of intracellular ph GO:0051453 1 0.011
cellular biosynthetic process GO:0044249 286 0.011
nuclear transport GO:0051169 4 0.011
rna metabolic process GO:0016070 219 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
cytokinesis GO:0000910 3 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
regulation of dendrite development GO:0050773 3 0.011
tissue remodeling GO:0048771 4 0.011
water homeostasis GO:0030104 4 0.011
response to carbohydrate GO:0009743 3 0.011
regulation of oligodendrocyte differentiation GO:0048713 1 0.011
neuron differentiation GO:0030182 353 0.011
cellular response to starvation GO:0009267 1 0.011
intracellular mrna localization GO:0008298 1 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
single fertilization GO:0007338 3 0.011
regulation of response to stimulus GO:0048583 269 0.011
oligopeptide transport GO:0006857 1 0.011
cytoplasm organization GO:0007028 4 0.011
autophagy GO:0006914 4 0.011
somatic stem cell maintenance GO:0035019 1 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
regulation of developmental process GO:0050793 247 0.011
nitric oxide metabolic process GO:0046209 2 0.011
regulation of reproductive process GO:2000241 4 0.011
regulation of oocyte development GO:0060281 3 0.011
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
circulatory system process GO:0003013 87 0.011
lateral line system development GO:0048925 76 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
protein import into nucleus GO:0006606 3 0.011
primary neural tube formation GO:0014020 1 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
neuron development GO:0048666 262 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
neuronal action potential GO:0019228 18 0.011
dipeptide transport GO:0042938 1 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
response to other organism GO:0051707 97 0.010
skeletal system development GO:0001501 181 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
locomotor rhythm GO:0045475 3 0.010
regulation of signaling GO:0023051 235 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of cardiac muscle tissue development GO:0055024 1 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
regulation of dna replication GO:0006275 3 0.010
regulation of binding GO:0051098 3 0.010
regulation of gene expression GO:0010468 265 0.010
regulation of autophagy GO:0010506 3 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
negative regulation of protein transport GO:0051224 3 0.010
kidney development GO:0001822 92 0.010
dna templated transcription elongation GO:0006354 3 0.010
adult behavior GO:0030534 2 0.010
osteoclast differentiation GO:0030316 1 0.010
histone h3 k4 methylation GO:0051568 2 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
proepicardium development GO:0003342 4 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
lamellipodium assembly GO:0030032 1 0.010
amino acid transport GO:0006865 2 0.010
neuron fate determination GO:0048664 2 0.010

trim2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.014
immune system disease DOID:2914 0 0.013
bone marrow disease DOID:4961 0 0.013
aplastic anemia DOID:12449 0 0.013
anemia DOID:2355 0 0.013
hematopoietic system disease DOID:74 0 0.013
musculoskeletal system disease DOID:17 0 0.012