Danio rerio

14 known processes

p2rx5

purinergic receptor P2X, ligand-gated ion channel, 5

(Aliases: p2x5)

p2rx5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.213
generation of neurons GO:0048699 385 0.153
locomotion GO:0040011 313 0.085
aging GO:0007568 2 0.082
nitrogen compound metabolic process GO:0006807 319 0.079
regulation of macromolecule metabolic process GO:0060255 317 0.078
response to chemical GO:0042221 320 0.073
system process GO:0003008 185 0.068
cell morphogenesis involved in differentiation GO:0000904 195 0.068
cell projection organization GO:0030030 284 0.064
single organism localization GO:1902578 225 0.064
immune system process GO:0002376 241 0.056
cellular macromolecule metabolic process GO:0044260 391 0.055
neuron differentiation GO:0030182 353 0.055
aromatic compound biosynthetic process GO:0019438 217 0.054
gene expression GO:0010467 252 0.053
cellular component morphogenesis GO:0032989 336 0.050
organic substance biosynthetic process GO:1901576 289 0.049
heterocycle metabolic process GO:0046483 290 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.048
central nervous system development GO:0007417 387 0.048
neuron development GO:0048666 262 0.047
regulation of biological quality GO:0065008 263 0.045
eye development GO:0001654 277 0.045
cellular component assembly GO:0022607 170 0.045
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.044
sensory organ development GO:0007423 393 0.044
response to external stimulus GO:0009605 264 0.043
muscle cell development GO:0055001 115 0.043
camera type eye development GO:0043010 222 0.043
cellular component movement GO:0006928 335 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.042
cellular nitrogen compound biosynthetic process GO:0044271 218 0.042
cell part morphogenesis GO:0032990 246 0.040
cell morphogenesis GO:0000902 289 0.040
regulation of cell projection assembly GO:0060491 4 0.039
mesenchymal cell development GO:0014031 78 0.039
rna localization GO:0006403 4 0.039
axon development GO:0061564 166 0.038
mechanosensory behavior GO:0007638 2 0.038
transport GO:0006810 220 0.038
lipid storage GO:0019915 1 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
regulation of biosynthetic process GO:0009889 250 0.037
neuron projection development GO:0031175 180 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
embryonic organ development GO:0048568 381 0.036
positive regulation of cell cycle GO:0045787 3 0.035
determination of bilateral symmetry GO:0009855 204 0.035
transcription dna templated GO:0006351 181 0.035
chemotaxis GO:0006935 104 0.034
axon guidance GO:0007411 86 0.034
hemopoiesis GO:0030097 183 0.034
regulation of rna metabolic process GO:0051252 224 0.034
cell projection morphogenesis GO:0048858 244 0.034
maintenance of location GO:0051235 4 0.033
cellular amine metabolic process GO:0044106 2 0.033
olfactory lobe development GO:0021988 4 0.033
vasculature development GO:0001944 278 0.033
blood vessel development GO:0001568 246 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
specification of symmetry GO:0009799 204 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.032
single organism transport GO:0044765 206 0.031
biosynthetic process GO:0009058 294 0.031
neuron projection guidance GO:0097485 86 0.031
sleep GO:0030431 1 0.031
nucleic acid metabolic process GO:0090304 244 0.031
myofibril assembly GO:0030239 48 0.030
localization of cell GO:0051674 244 0.030
adult behavior GO:0030534 2 0.030
cell projection assembly GO:0030031 64 0.030
regulation of rna biosynthetic process GO:2001141 213 0.030
cell migration GO:0016477 237 0.030
regulation of metabolic process GO:0019222 359 0.030
organic cyclic compound metabolic process GO:1901360 301 0.030
cellular biosynthetic process GO:0044249 286 0.030
regulation of circadian rhythm GO:0042752 4 0.029
somatic muscle development GO:0007525 4 0.029
regulation of nucleic acid templated transcription GO:1903506 213 0.029
protein import into nucleus GO:0006606 3 0.029
cilium morphogenesis GO:0060271 85 0.029
olfactory bulb development GO:0021772 4 0.029
regulation of binding GO:0051098 3 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
macromolecule biosynthetic process GO:0009059 227 0.029
rna metabolic process GO:0016070 219 0.029
forebrain development GO:0030900 96 0.028
axonogenesis GO:0007409 152 0.028
striated muscle cell differentiation GO:0051146 129 0.028
cell substrate adhesion GO:0031589 4 0.028
muscle structure development GO:0061061 196 0.028
regulation of synaptic plasticity GO:0048167 1 0.028
regulation of reproductive process GO:2000241 4 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
neurological system process GO:0050877 62 0.027
developmental growth GO:0048589 166 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
protein localization to nucleus GO:0034504 3 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
positive regulation of biological process GO:0048518 253 0.027
nuclear transport GO:0051169 4 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
transmission of nerve impulse GO:0019226 19 0.027
stem cell maintenance GO:0019827 4 0.026
heart morphogenesis GO:0003007 156 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
forebrain cell migration GO:0021885 1 0.026
single organism metabolic process GO:0044710 217 0.026
taxis GO:0042330 109 0.026
brain development GO:0007420 293 0.026
angiogenesis GO:0001525 158 0.026
small molecule metabolic process GO:0044281 77 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
nucleic acid templated transcription GO:0097659 181 0.025
response to organic substance GO:0010033 153 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
spermatid development GO:0007286 2 0.025
positive regulation of transport GO:0051050 2 0.024
microtubule organizing center organization GO:0031023 1 0.024
regulation of primary metabolic process GO:0080090 311 0.024
tube morphogenesis GO:0035239 349 0.024
circadian sleep wake cycle sleep GO:0050802 1 0.024
multicellular organismal response to stress GO:0033555 2 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
meiotic nuclear division GO:0007126 4 0.024
regulation of signal transduction GO:0009966 225 0.024
stem cell proliferation GO:0072089 4 0.023
immune system development GO:0002520 191 0.023
neuron projection morphogenesis GO:0048812 161 0.023
regulation of protein transport GO:0051223 3 0.023
regulation of synapse assembly GO:0051963 3 0.023
blood vessel morphogenesis GO:0048514 216 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.022
septum transversum development GO:0003343 4 0.022
digestive tract morphogenesis GO:0048546 231 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
regulation of signaling GO:0023051 235 0.022
response to stress GO:0006950 263 0.022
amine metabolic process GO:0009308 2 0.022
establishment of localization GO:0051234 244 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
regulation of gene expression GO:0010468 265 0.022
digestive tract development GO:0048565 265 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
multicellular organism growth GO:0035264 4 0.021
muscle cell differentiation GO:0042692 139 0.021
protein targeting to nucleus GO:0044744 3 0.021
muscle tissue development GO:0060537 110 0.021
dna templated transcription initiation GO:0006352 1 0.021
regulation of developmental process GO:0050793 247 0.021
signal transduction GO:0007165 455 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
cellular ketone metabolic process GO:0042180 11 0.021
cognition GO:0050890 1 0.020
ion transport GO:0006811 114 0.020
heart development GO:0007507 313 0.020
regulation of cell communication GO:0010646 232 0.020
locomotor rhythm GO:0045475 3 0.020
protein import GO:0017038 3 0.020
pectoral fin development GO:0033339 50 0.020
circadian sleep wake cycle GO:0042745 2 0.020
negative regulation of signaling GO:0023057 96 0.020
response to abiotic stimulus GO:0009628 122 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
phagocytosis GO:0006909 3 0.019
positive regulation of stem cell proliferation GO:2000648 1 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
centrosome organization GO:0051297 1 0.019
skeletal system development GO:0001501 181 0.019
renal system development GO:0072001 94 0.019
water homeostasis GO:0030104 4 0.019
pharyngeal muscle development GO:0043282 4 0.019
determination of left right symmetry GO:0007368 179 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
transmembrane transport GO:0055085 120 0.019
negative regulation of biological process GO:0048519 304 0.019
striated muscle cell development GO:0055002 108 0.019
head development GO:0060322 303 0.019
organelle organization GO:0006996 227 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
heart process GO:0003015 71 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.018
multicellular organismal signaling GO:0035637 22 0.018
cellular aldehyde metabolic process GO:0006081 4 0.018
regulation of dendrite development GO:0050773 3 0.018
single organism organelle organization GO:1902589 199 0.018
urogenital system development GO:0001655 97 0.018
behavior GO:0007610 74 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
organelle assembly GO:0070925 110 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
retina development in camera type eye GO:0060041 146 0.018
sodium ion transport GO:0006814 24 0.018
embryonic heart tube morphogenesis GO:0003143 108 0.018
organic acid metabolic process GO:0006082 31 0.017
regulation of synapse organization GO:0050807 3 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
regulation of protein complex assembly GO:0043254 3 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
digestive system development GO:0055123 289 0.017
kidney development GO:0001822 92 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of protein catabolic process GO:0042176 1 0.017
skeletal muscle organ development GO:0060538 78 0.017
developmental growth involved in morphogenesis GO:0060560 86 0.017
endocrine system development GO:0035270 65 0.017
rna biosynthetic process GO:0032774 181 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
response to oxygen containing compound GO:1901700 55 0.017
compound eye development GO:0048749 2 0.017
regulation of cell shape GO:0008360 1 0.017
motor neuron axon guidance GO:0008045 23 0.017
mesenchyme development GO:0060485 127 0.017
regulation of blood pressure GO:0008217 1 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
somitogenesis GO:0001756 87 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
neuroblast proliferation GO:0007405 2 0.016
positive regulation of catabolic process GO:0009896 4 0.016
estrogen metabolic process GO:0008210 2 0.016
gastrulation GO:0007369 208 0.016
regulation of muscle contraction GO:0006937 3 0.016
positive regulation of epithelial cell differentiation GO:0030858 2 0.016
negative regulation of multicellular organismal process GO:0051241 69 0.016
response to hormone GO:0009725 48 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
negative regulation of catabolic process GO:0009895 3 0.016
chordate embryonic development GO:0043009 271 0.016
embryonic heart tube development GO:0035050 133 0.015
anterior posterior pattern specification GO:0009952 152 0.015
striated muscle tissue development GO:0014706 110 0.015
branching morphogenesis of a nerve GO:0048755 4 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
response to glucocorticoid GO:0051384 1 0.015
mesenchymal cell differentiation GO:0048762 87 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
circulatory system process GO:0003013 87 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
regulation of transcription dna templated GO:0006355 213 0.015
atp catabolic process GO:0006200 4 0.015
tissue remodeling GO:0048771 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
cilium organization GO:0044782 71 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
synaptic transmission cholinergic GO:0007271 4 0.015
intracellular mrna localization GO:0008298 1 0.015
chemosensory behavior GO:0007635 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
mitochondrion organization GO:0007005 4 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
muscle fiber development GO:0048747 52 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
protein polymerization GO:0051258 4 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
regeneration GO:0031099 91 0.015
myeloid cell differentiation GO:0030099 86 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
response to corticosteroid GO:0031960 1 0.014
ovulation cycle process GO:0022602 2 0.014
neuronal action potential GO:0019228 18 0.014
lamellipodium organization GO:0097581 1 0.014
centrosome cycle GO:0007098 1 0.014
nuclear import GO:0051170 3 0.014
cell motility GO:0048870 244 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
oocyte maturation GO:0001556 4 0.014
diterpenoid metabolic process GO:0016101 15 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
spermatid differentiation GO:0048515 2 0.014
muscle organ development GO:0007517 101 0.014
sensory organ morphogenesis GO:0090596 200 0.014
regulation of cytokine production GO:0001817 3 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of localization GO:0032879 104 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cellular component disassembly GO:0022411 1 0.013
somite development GO:0061053 96 0.013
apoptotic process involved in development GO:1902742 2 0.013
sodium ion transmembrane transport GO:0035725 21 0.013
secondary metabolic process GO:0019748 3 0.013
response to monosaccharide GO:0034284 3 0.013
erythrocyte development GO:0048821 24 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of sodium ion transport GO:0002028 2 0.013
lipid catabolic process GO:0016042 4 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
action potential GO:0001508 19 0.013
peptidyl serine modification GO:0018209 2 0.013
neural crest cell development GO:0014032 62 0.013
positive regulation of cellular process GO:0048522 201 0.013
skeletal muscle tissue development GO:0007519 67 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
embryonic skeletal system development GO:0048706 97 0.013
regionalization GO:0003002 274 0.013
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
organism emergence from protective structure GO:0071684 4 0.013
regulation of neurological system process GO:0031644 2 0.013
gtp metabolic process GO:0046039 4 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.013
response to carbohydrate GO:0009743 3 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
cell matrix adhesion GO:0007160 4 0.012
response to organic cyclic compound GO:0014070 51 0.012
stem cell development GO:0048864 82 0.012
glial cell migration GO:0008347 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
cell fate commitment GO:0045165 99 0.012
establishment of rna localization GO:0051236 3 0.012
ion transmembrane transport GO:0034220 91 0.012
positive regulation of blood circulation GO:1903524 2 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
cation transport GO:0006812 81 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
cytoplasm organization GO:0007028 4 0.012
exocytosis GO:0006887 1 0.012
monoamine transport GO:0015844 1 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
female sex differentiation GO:0046660 4 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
fin development GO:0033333 77 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
trabecula morphogenesis GO:0061383 2 0.012
leukocyte proliferation GO:0070661 1 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of extent of cell growth GO:0061387 29 0.011
cellular response to external stimulus GO:0071496 2 0.011
eye photoreceptor cell differentiation GO:0001754 45 0.011
nuclear export GO:0051168 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
catecholamine metabolic process GO:0006584 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
vacuolar transport GO:0007034 2 0.011
regulation of protein targeting GO:1903533 2 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
appendage development GO:0048736 80 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
positive regulation of secretion GO:0051047 1 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
anterior lateral line nerve development GO:0048909 4 0.011
protein metabolic process GO:0019538 183 0.011
protein depolymerization GO:0051261 1 0.011
central nervous system neuron development GO:0021954 29 0.011
cellular localization GO:0051641 97 0.011
membrane repolarization GO:0086009 2 0.011
regulation of protein binding GO:0043393 3 0.011
smooth muscle contraction GO:0006939 2 0.011
eye morphogenesis GO:0048592 144 0.011
neurotransmitter transport GO:0006836 2 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
regulation of myotube differentiation GO:0010830 2 0.011
sprouting angiogenesis GO:0002040 53 0.011
negative regulation of cell communication GO:0010648 96 0.011
positive regulation of gene expression GO:0010628 71 0.011
regulation of filopodium assembly GO:0051489 2 0.011
basement membrane assembly GO:0070831 3 0.011
cellular response to oxygen levels GO:0071453 1 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
androgen metabolic process GO:0008209 2 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
oxoacid metabolic process GO:0043436 31 0.011
cell cycle arrest GO:0007050 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
pole plasm assembly GO:0007315 4 0.011
antimicrobial humoral response GO:0019730 2 0.011
response to hexose GO:0009746 3 0.011
epithelial cell differentiation GO:0030855 116 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
Zebrafish
regulation of neurogenesis GO:0050767 87 0.011
lens fiber cell morphogenesis GO:0070309 3 0.011
aorta development GO:0035904 4 0.010
protein homooligomerization GO:0051260 3 0.010
regulation of cell size GO:0008361 29 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
response to lipid GO:0033993 60 0.010
protein stabilization GO:0050821 2 0.010
nucleic acid transport GO:0050657 2 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
mononuclear cell proliferation GO:0032943 1 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
blood circulation GO:0008015 87 0.010
response to uv GO:0009411 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
negative regulation of developmental process GO:0051093 65 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
heart contraction GO:0060047 71 0.010
hypothalamus cell differentiation GO:0021979 4 0.010
response to light stimulus GO:0009416 46 0.010
membrane invagination GO:0010324 1 0.010
carbohydrate homeostasis GO:0033500 1 0.010
stem cell division GO:0017145 1 0.010
post embryonic organ development GO:0048569 4 0.010
segmentation GO:0035282 97 0.010
regulation of developmental growth GO:0048638 38 0.010
heart looping GO:0001947 94 0.010
muscle attachment GO:0016203 9 0.010
embryonic pectoral fin morphogenesis GO:0035118 24 0.010
homeostatic process GO:0042592 142 0.010
axon extension GO:0048675 45 0.010

p2rx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.018
disease of metabolism DOID:0014667 0 0.015
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
nervous system disease DOID:863 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
cardiovascular system disease DOID:1287 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011