Danio rerio

0 known processes

zgc:153035

zgc:153035

(Aliases: hlfa,HLF1)

zgc:153035 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.085
sensory organ development GO:0007423 393 0.083
regulation of biological quality GO:0065008 263 0.070
aging GO:0007568 2 0.055
negative regulation of biological process GO:0048519 304 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.035
transcription from rna polymerase ii promoter GO:0006366 80 0.035
cellular carbohydrate metabolic process GO:0044262 4 0.035
positive regulation of catabolic process GO:0009896 4 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
regulation of protein catabolic process GO:0042176 1 0.033
positive regulation of transport GO:0051050 2 0.033
sensory system development GO:0048880 76 0.032
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.032
regulation of neural precursor cell proliferation GO:2000177 3 0.031
ameboidal type cell migration GO:0001667 143 0.031
stem cell maintenance GO:0019827 4 0.031
gene expression GO:0010467 252 0.031
heterocycle biosynthetic process GO:0018130 215 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
morphogenesis of an epithelium GO:0002009 333 0.030
regulation of reactive oxygen species metabolic process GO:2000377 2 0.030
positive regulation of cytokine production GO:0001819 2 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
regulation of protein complex assembly GO:0043254 3 0.029
response to monosaccharide GO:0034284 3 0.029
response to carbohydrate GO:0009743 3 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
regulation of cytokine production GO:0001817 3 0.028
cellular response to nutrient levels GO:0031669 2 0.028
proteasomal protein catabolic process GO:0010498 2 0.028
cellular response to oxygen levels GO:0071453 1 0.027
negative regulation of mapk cascade GO:0043409 4 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
nucleic acid templated transcription GO:0097659 181 0.027
embryonic organ development GO:0048568 381 0.027
aromatic compound biosynthetic process GO:0019438 217 0.026
i kappab kinase nf kappab signaling GO:0007249 4 0.026
regulation of circadian rhythm GO:0042752 4 0.026
immune system process GO:0002376 241 0.026
nitric oxide metabolic process GO:0046209 2 0.026
cellular component disassembly GO:0022411 1 0.026
nucleocytoplasmic transport GO:0006913 4 0.025
response to hexose GO:0009746 3 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
meiotic nuclear division GO:0007126 4 0.025
response to chemical GO:0042221 320 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
response to glucose GO:0009749 3 0.025
autophagy GO:0006914 4 0.025
regulation of developmental process GO:0050793 247 0.025
protein polymerization GO:0051258 4 0.024
protein localization to nucleus GO:0034504 3 0.024
heart development GO:0007507 313 0.024
heterocycle metabolic process GO:0046483 290 0.024
leukocyte proliferation GO:0070661 1 0.024
amine metabolic process GO:0009308 2 0.024
cell motility GO:0048870 244 0.024
establishment of localization GO:0051234 244 0.024
regulation of rna metabolic process GO:0051252 224 0.024
lateral line system development GO:0048925 76 0.024
nuclear transport GO:0051169 4 0.024
regulation of gene expression GO:0010468 265 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
response to uv GO:0009411 3 0.023
response to biotic stimulus GO:0009607 97 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
meiotic cell cycle process GO:1903046 3 0.023
regulation of sodium ion transport GO:0002028 2 0.023
multicellular organism growth GO:0035264 4 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
single organism nuclear import GO:1902593 3 0.023
locomotion GO:0040011 313 0.023
regulation of transcription dna templated GO:0006355 213 0.022
maintenance of location GO:0051235 4 0.022
cellular ketone metabolic process GO:0042180 11 0.022
positive regulation of cell cycle GO:0045787 3 0.022
regulation of response to stimulus GO:0048583 269 0.022
regulation of organ growth GO:0046620 3 0.022
regulation of metabolic process GO:0019222 359 0.022
protein heterooligomerization GO:0051291 1 0.022
response to other organism GO:0051707 97 0.021
retina development in camera type eye GO:0060041 146 0.021
negative regulation of cellular process GO:0048523 283 0.021
ear development GO:0043583 127 0.021
cellular response to light stimulus GO:0071482 4 0.021
nucleic acid metabolic process GO:0090304 244 0.021
regulation of binding GO:0051098 3 0.021
cellular biosynthetic process GO:0044249 286 0.021
cellular protein catabolic process GO:0044257 4 0.021
response to external stimulus GO:0009605 264 0.021
phagocytosis GO:0006909 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
transport GO:0006810 220 0.020
regulation of cell shape GO:0008360 1 0.020
reactive oxygen species metabolic process GO:0072593 6 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
transcription dna templated GO:0006351 181 0.020
stem cell fate commitment GO:0048865 1 0.020
developmental programmed cell death GO:0010623 4 0.020
peptide transport GO:0015833 1 0.020
energy reserve metabolic process GO:0006112 2 0.020
signal transduction GO:0007165 455 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
tube morphogenesis GO:0035239 349 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
organic substance biosynthetic process GO:1901576 289 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
carbohydrate biosynthetic process GO:0016051 1 0.019
sensory organ morphogenesis GO:0090596 200 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
homeostatic process GO:0042592 142 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
digestive tract development GO:0048565 265 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
smooth muscle contraction GO:0006939 2 0.019
regulation of signal transduction GO:0009966 225 0.019
rna biosynthetic process GO:0032774 181 0.019
protein targeting to nucleus GO:0044744 3 0.019
meiotic chromosome segregation GO:0045132 3 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
transmission of nerve impulse GO:0019226 19 0.018
eye development GO:0001654 277 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
lipid homeostasis GO:0055088 3 0.018
response to ketone GO:1901654 1 0.018
biosynthetic process GO:0009058 294 0.018
mononuclear cell proliferation GO:0032943 1 0.018
digestive tract morphogenesis GO:0048546 231 0.018
carbohydrate homeostasis GO:0033500 1 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
mechanosensory lateral line system development GO:0048881 49 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
digestive system development GO:0055123 289 0.018
membrane invagination GO:0010324 1 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
cellular response to organic substance GO:0071310 105 0.018
muscle tissue development GO:0060537 110 0.018
atp catabolic process GO:0006200 4 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
organelle assembly GO:0070925 110 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
cellular component morphogenesis GO:0032989 336 0.017
stem cell proliferation GO:0072089 4 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
sleep GO:0030431 1 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
regulation of muscle contraction GO:0006937 3 0.017
regulation of inflammatory response GO:0050727 2 0.017
response to external biotic stimulus GO:0043207 97 0.017
protein import into nucleus GO:0006606 3 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
response to drug GO:0042493 3 0.017
regulation of carbohydrate metabolic process GO:0006109 4 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
regulation of blood vessel size GO:0050880 2 0.017
histone h3 k4 methylation GO:0051568 2 0.017
cellular amine metabolic process GO:0044106 2 0.017
regulation of tube size GO:0035150 2 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
regulation of metal ion transport GO:0010959 4 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
cellular response to starvation GO:0009267 1 0.016
protein import GO:0017038 3 0.016
regulation of cell differentiation GO:0045595 142 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
meiosis i GO:0007127 1 0.016
cognition GO:0050890 1 0.016
startle response GO:0001964 4 0.016
rna metabolic process GO:0016070 219 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
neuromast development GO:0048884 46 0.016
regulation of cell activation GO:0050865 1 0.015
central nervous system development GO:0007417 387 0.015
glucose homeostasis GO:0042593 1 0.015
adherens junction organization GO:0034332 4 0.015
striated muscle tissue development GO:0014706 110 0.015
cell substrate adhesion GO:0031589 4 0.015
regulation of autophagy GO:0010506 3 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
protein stabilization GO:0050821 2 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
gland development GO:0048732 143 0.015
protein complex disassembly GO:0043241 1 0.015
response to nutrient GO:0007584 3 0.015
locomotor rhythm GO:0045475 3 0.015
post embryonic organ development GO:0048569 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
nuclear import GO:0051170 3 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
regulation of circadian sleep wake cycle GO:0042749 1 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
organelle organization GO:0006996 227 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
embryonic heart tube development GO:0035050 133 0.014
camera type eye development GO:0043010 222 0.014
response to corticosteroid GO:0031960 1 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
generation of neurons GO:0048699 385 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
cellular component assembly GO:0022607 170 0.014
b cell activation GO:0042113 2 0.014
phagocytosis engulfment GO:0006911 1 0.014
adult behavior GO:0030534 2 0.014
head development GO:0060322 303 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
centrosome organization GO:0051297 1 0.014
mitochondrion organization GO:0007005 4 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
inner ear development GO:0048839 126 0.014
system process GO:0003008 185 0.014
apoptotic process involved in development GO:1902742 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
cell matrix adhesion GO:0007160 4 0.014
estrogen metabolic process GO:0008210 2 0.014
regulation of reproductive process GO:2000241 4 0.014
reactive oxygen species biosynthetic process GO:1903409 1 0.014
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.014
localization of cell GO:0051674 244 0.014
single organism localization GO:1902578 225 0.014
cellular component movement GO:0006928 335 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.013
chemical homeostasis GO:0048878 49 0.013
vasculature development GO:0001944 278 0.013
blood circulation GO:0008015 87 0.013
lateral line development GO:0048882 66 0.013
response to topologically incorrect protein GO:0035966 2 0.013
determination of bilateral symmetry GO:0009855 204 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
determination of left right symmetry GO:0007368 179 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
positive regulation of biological process GO:0048518 253 0.013
regulation of protein transport GO:0051223 3 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
regulation of primary metabolic process GO:0080090 311 0.013
specification of symmetry GO:0009799 204 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
response to alkaloid GO:0043279 2 0.013
ion transmembrane transport GO:0034220 91 0.013
cell migration GO:0016477 237 0.013
regulation of blood pressure GO:0008217 1 0.013
cell part morphogenesis GO:0032990 246 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
brain development GO:0007420 293 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
action potential GO:0001508 19 0.013
lipid storage GO:0019915 1 0.013
female sex differentiation GO:0046660 4 0.012
neuronal action potential GO:0019228 18 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
regulation of protein binding GO:0043393 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
mesenchyme development GO:0060485 127 0.012
lymphocyte proliferation GO:0046651 1 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
death GO:0016265 121 0.012
response to stress GO:0006950 263 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
organic acid metabolic process GO:0006082 31 0.012
female gonad development GO:0008585 4 0.012
gtp catabolic process GO:0006184 2 0.012
multicellular organismal signaling GO:0035637 22 0.012
response to organic substance GO:0010033 153 0.012
developmental pigmentation GO:0048066 48 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
immune system development GO:0002520 191 0.012
trabecula morphogenesis GO:0061383 2 0.012
regulation of transporter activity GO:0032409 2 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
gastrulation GO:0007369 208 0.012
nuclear export GO:0051168 1 0.012
monoamine transport GO:0015844 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
cellular response to hypoxia GO:0071456 1 0.012
response to abiotic stimulus GO:0009628 122 0.012
embryonic skeletal joint development GO:0072498 3 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
cardiac conduction GO:0061337 3 0.012
chordate embryonic development GO:0043009 271 0.012
response to bacterium GO:0009617 58 0.012
regulation of mrna processing GO:0050684 3 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
cell substrate junction assembly GO:0007044 2 0.011
positive regulation of secretion GO:0051047 1 0.011
gtp metabolic process GO:0046039 4 0.011
oxoacid metabolic process GO:0043436 31 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
positive regulation of metabolic process GO:0009893 108 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
cell death GO:0008219 121 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
apoptotic process involved in morphogenesis GO:0060561 2 0.011
protein complex localization GO:0031503 1 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
regulation of dendrite development GO:0050773 3 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
neuron development GO:0048666 262 0.011
blood vessel development GO:0001568 246 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of protein polymerization GO:0032271 2 0.011
single organism transport GO:0044765 206 0.011
urogenital system development GO:0001655 97 0.011
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.011
muscle cell development GO:0055001 115 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
negative regulation of defense response GO:0031348 2 0.011
response to glucocorticoid GO:0051384 1 0.011
positive regulation of cell activation GO:0050867 1 0.011
myeloid cell differentiation GO:0030099 86 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
protein secretion GO:0009306 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
zymogen activation GO:0031638 3 0.011
mrna 3 end processing GO:0031124 2 0.011
cellular component biogenesis GO:0044085 178 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cell projection morphogenesis GO:0048858 244 0.011
regulation of dna replication GO:0006275 3 0.011
pigmentation GO:0043473 85 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
response to vitamin GO:0033273 3 0.011
negative regulation of rna metabolic process GO:0051253 48 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
medulla oblongata development GO:0021550 4 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
cell proliferation GO:0008283 80 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
hormone secretion GO:0046879 2 0.010
cell morphogenesis GO:0000902 289 0.010
mesoderm development GO:0007498 88 0.010
angiogenesis GO:0001525 158 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
negative regulation of cytokine production GO:0001818 1 0.010
long chain fatty acid metabolic process GO:0001676 1 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
single organism organelle organization GO:1902589 199 0.010
regulation of signaling GO:0023051 235 0.010
negative regulation of gene expression GO:0010629 65 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of locomotion GO:0040012 55 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
cell projection organization GO:0030030 284 0.010
kidney development GO:0001822 92 0.010
embryonic skeletal joint morphogenesis GO:0060272 3 0.010

zgc:153035 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.011
cardiovascular system disease DOID:1287 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010