Danio rerio

0 known processes

atg12

ATG12 autophagy related 12 homolog (S. cerevisiae)

atg12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.080
larval development GO:0002164 2 0.069
embryonic organ morphogenesis GO:0048562 274 0.059
embryo development ending in birth or egg hatching GO:0009792 271 0.049
protein localization to nucleus GO:0034504 3 0.048
sensory organ development GO:0007423 393 0.045
modification dependent macromolecule catabolic process GO:0043632 3 0.042
generation of neurons GO:0048699 385 0.041
biosynthetic process GO:0009058 294 0.041
neuron differentiation GO:0030182 353 0.039
cellular protein catabolic process GO:0044257 4 0.035
aging GO:0007568 2 0.035
nuclear transport GO:0051169 4 0.034
organonitrogen compound metabolic process GO:1901564 74 0.031
neuron development GO:0048666 262 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
b cell activation GO:0042113 2 0.030
response to glucocorticoid GO:0051384 1 0.030
positive regulation of epithelial cell differentiation GO:0030858 2 0.030
cytokinetic process GO:0032506 2 0.029
mesenchyme development GO:0060485 127 0.029
response to corticosteroid GO:0031960 1 0.028
heart development GO:0007507 313 0.028
muscle tissue development GO:0060537 110 0.027
stem cell maintenance GO:0019827 4 0.027
lipid storage GO:0019915 1 0.027
organelle fusion GO:0048284 3 0.026
transcription dna templated GO:0006351 181 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
regulation of blood pressure GO:0008217 1 0.025
directional locomotion GO:0033058 1 0.024
calcium ion transport into cytosol GO:0060402 3 0.024
mechanosensory lateral line system development GO:0048881 49 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
chordate embryonic development GO:0043009 271 0.024
tube morphogenesis GO:0035239 349 0.024
nuclear import GO:0051170 3 0.024
single organism nuclear import GO:1902593 3 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
inner ear receptor cell fate commitment GO:0060120 4 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
positive regulation of myeloid cell differentiation GO:0045639 2 0.023
single organism metabolic process GO:0044710 217 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
maintenance of location GO:0051235 4 0.023
sex determination GO:0007530 1 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
positive regulation of cell cycle GO:0045787 3 0.023
b cell differentiation GO:0030183 1 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
cellular response to external stimulus GO:0071496 2 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
calcium ion import GO:0070509 4 0.022
cellular biosynthetic process GO:0044249 286 0.022
cellular amine metabolic process GO:0044106 2 0.022
protein import into nucleus GO:0006606 3 0.021
protein import GO:0017038 3 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
regulation of metabolic process GO:0019222 359 0.021
regulation of tube size GO:0035150 2 0.021
cellular response to nutrient levels GO:0031669 2 0.020
cellular response to starvation GO:0009267 1 0.020
somite development GO:0061053 96 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
determination of bilateral symmetry GO:0009855 204 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
embryonic skeletal system morphogenesis GO:0048704 93 0.020
embryonic heart tube morphogenesis GO:0003143 108 0.020
skeletal muscle tissue development GO:0007519 67 0.020
cellular ketone metabolic process GO:0042180 11 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
protein targeting to nucleus GO:0044744 3 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
locomotion GO:0040011 313 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.019
negative regulation of reproductive process GO:2000242 3 0.019
positive regulation of transport GO:0051050 2 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
cytokinesis GO:0000910 3 0.019
regulation of cytokine production GO:0001817 3 0.019
cell death GO:0008219 121 0.019
response to glucose GO:0009749 3 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
stem cell proliferation GO:0072089 4 0.019
negative regulation of leukocyte differentiation GO:1902106 1 0.019
heart looping GO:0001947 94 0.018
cell cycle arrest GO:0007050 1 0.018
regulation of protein catabolic process GO:0042176 1 0.018
sensory perception of chemical stimulus GO:0007606 3 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
regulation of erythrocyte differentiation GO:0045646 2 0.018
compound eye development GO:0048749 2 0.017
negative regulation of myeloid cell differentiation GO:0045638 1 0.017
regulation of protein targeting GO:1903533 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
synaptic vesicle transport GO:0048489 1 0.017
auditory receptor cell fate commitment GO:0009912 4 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
response to chemical GO:0042221 320 0.017
small molecule metabolic process GO:0044281 77 0.017
hormone biosynthetic process GO:0042446 3 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
cell part morphogenesis GO:0032990 246 0.017
neuroblast proliferation GO:0007405 2 0.017
positive regulation of catabolic process GO:0009896 4 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
muscle cell development GO:0055001 115 0.017
heterocycle metabolic process GO:0046483 290 0.017
multicellular organism growth GO:0035264 4 0.016
signal transduction GO:0007165 455 0.016
autophagy GO:0006914 4 0.016
regulation of signal transduction GO:0009966 225 0.016
heart morphogenesis GO:0003007 156 0.016
lateral line system development GO:0048925 76 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of signaling GO:0023051 235 0.016
cognition GO:0050890 1 0.016
olfactory bulb development GO:0021772 4 0.016
endocrine process GO:0050886 2 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
mitochondrion organization GO:0007005 4 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
cell migration GO:0016477 237 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
heme metabolic process GO:0042168 9 0.016
olfactory lobe development GO:0021988 4 0.016
eye development GO:0001654 277 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
regulation of cell death GO:0010941 103 0.016
cell projection morphogenesis GO:0048858 244 0.015
regulation of reproductive process GO:2000241 4 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
sensory organ morphogenesis GO:0090596 200 0.015
protein polyubiquitination GO:0000209 4 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
organic substance biosynthetic process GO:1901576 289 0.015
single organism membrane fusion GO:0044801 2 0.015
regulation of protein transport GO:0051223 3 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
glucose homeostasis GO:0042593 1 0.015
oocyte maturation GO:0001556 4 0.015
embryonic skeletal system development GO:0048706 97 0.015
cellular component movement GO:0006928 335 0.015
synaptic vesicle localization GO:0097479 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
meiotic nuclear division GO:0007126 4 0.014
regulation of cell communication GO:0010646 232 0.014
amine metabolic process GO:0009308 2 0.014
organelle assembly GO:0070925 110 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
response to nutrient GO:0007584 3 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
response to monosaccharide GO:0034284 3 0.014
peptide transport GO:0015833 1 0.014
regionalization GO:0003002 274 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
immune system process GO:0002376 241 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
regulation of cell activation GO:0050865 1 0.014
single organism organelle organization GO:1902589 199 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
regulation of organelle assembly GO:1902115 4 0.014
vasculature development GO:0001944 278 0.014
negative regulation of kinase activity GO:0033673 4 0.014
hepaticobiliary system development GO:0061008 98 0.014
positive regulation of biological process GO:0048518 253 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.013
response to hexose GO:0009746 3 0.013
negative regulation of tor signaling GO:0032007 2 0.013
response to drug GO:0042493 3 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
death GO:0016265 121 0.013
golgi vesicle transport GO:0048193 3 0.013
programmed cell death GO:0012501 119 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
response to ketone GO:1901654 1 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
regulation of blood vessel size GO:0050880 2 0.013
protein modification by small protein removal GO:0070646 1 0.013
phagocytosis GO:0006909 3 0.013
regulation of programmed cell death GO:0043067 101 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
hypothalamus cell differentiation GO:0021979 4 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
muscle structure development GO:0061061 196 0.013
striated muscle tissue development GO:0014706 110 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
eye morphogenesis GO:0048592 144 0.013
carbohydrate homeostasis GO:0033500 1 0.013
apoptotic process GO:0006915 116 0.013
response to uv GO:0009411 3 0.013
locomotor rhythm GO:0045475 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
smooth muscle contraction GO:0006939 2 0.013
regulation of endothelial cell proliferation GO:0001936 1 0.013
angiogenesis GO:0001525 158 0.013
rna metabolic process GO:0016070 219 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
cellular component disassembly GO:0022411 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
skeletal system development GO:0001501 181 0.013
single fertilization GO:0007338 3 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
anterior posterior pattern specification GO:0009952 152 0.013
determination of intestine left right asymmetry GO:0071908 2 0.013
digestive system development GO:0055123 289 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
central nervous system development GO:0007417 387 0.012
cellular respiration GO:0045333 3 0.012
leukocyte proliferation GO:0070661 1 0.012
atp catabolic process GO:0006200 4 0.012
transport GO:0006810 220 0.012
sensory system development GO:0048880 76 0.012
membrane invagination GO:0010324 1 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
protein metabolic process GO:0019538 183 0.012
cell proliferation in forebrain GO:0021846 3 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
porphyrin containing compound metabolic process GO:0006778 10 0.012
regulation of gene expression GO:0010468 265 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
response to unfolded protein GO:0006986 2 0.012
membrane fusion GO:0061025 2 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.012
centrosome organization GO:0051297 1 0.012
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
glial cell migration GO:0008347 3 0.012
gtp catabolic process GO:0006184 2 0.012
exocytosis GO:0006887 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
neuron fate determination GO:0048664 2 0.012
regulation of binding GO:0051098 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
neuron projection development GO:0031175 180 0.012
glutamate receptor signaling pathway GO:0007215 1 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
tissue remodeling GO:0048771 4 0.012
striated muscle cell development GO:0055002 108 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
embryonic heart tube development GO:0035050 133 0.011
specification of symmetry GO:0009799 204 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
regulation of apoptotic process GO:0042981 98 0.011
cellular component morphogenesis GO:0032989 336 0.011
photoreceptor cell differentiation GO:0046530 55 0.011
somitogenesis GO:0001756 87 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
meiotic cell cycle process GO:1903046 3 0.011
regulation of circadian rhythm GO:0042752 4 0.011
cilium morphogenesis GO:0060271 85 0.011
cellular component biogenesis GO:0044085 178 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
lateral inhibition GO:0046331 1 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
determination of left right symmetry GO:0007368 179 0.011
adult behavior GO:0030534 2 0.011
response to topologically incorrect protein GO:0035966 2 0.011
energy reserve metabolic process GO:0006112 2 0.011
p38mapk cascade GO:0038066 1 0.011
specification of axis polarity GO:0065001 4 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
macroautophagy GO:0016236 1 0.011
positive regulation of blood circulation GO:1903524 2 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
brain development GO:0007420 293 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
actomyosin structure organization GO:0031032 53 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cellular response to stress GO:0033554 62 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
organic acid metabolic process GO:0006082 31 0.011
blood vessel development GO:0001568 246 0.010
startle response GO:0001964 4 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
camera type eye development GO:0043010 222 0.010
cell aging GO:0007569 2 0.010
cell substrate adhesion GO:0031589 4 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
regulation of biological quality GO:0065008 263 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
regulation of response to stimulus GO:0048583 269 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
neurotransmitter transport GO:0006836 2 0.010
zymogen activation GO:0031638 3 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of cellular process GO:0048523 283 0.010
stem cell differentiation GO:0048863 117 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
establishment of localization GO:0051234 244 0.010
cell morphogenesis GO:0000902 289 0.010
microtubule based process GO:0007017 60 0.010
head development GO:0060322 303 0.010
er nucleus signaling pathway GO:0006984 2 0.010
single organism biosynthetic process GO:0044711 71 0.010
neural crest cell differentiation GO:0014033 72 0.010
negative regulation of protein transport GO:0051224 3 0.010
positive regulation of signaling GO:0023056 56 0.010
negative regulation of multi organism process GO:0043901 3 0.010
fat soluble vitamin metabolic process GO:0006775 4 0.010
secondary metabolic process GO:0019748 3 0.010
regulation of dendrite development GO:0050773 3 0.010
negative regulation of catabolic process GO:0009895 3 0.010
skeletal muscle organ development GO:0060538 78 0.010
signal transduction by p53 class mediator GO:0072331 13 0.010
androgen biosynthetic process GO:0006702 1 0.010
protein complex disassembly GO:0043241 1 0.010
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.010

atg12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.013
nervous system disease DOID:863 0 0.012
musculoskeletal system disease DOID:17 0 0.011