Danio rerio

10 known processes

tjp3

tight junction protein 3

(Aliases: wu:fj93c08,cb766)

tjp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule biosynthetic process GO:0034645 224 0.579
oxoacid metabolic process GO:0043436 31 0.343
liver development GO:0001889 96 0.297
s adenosylmethionine metabolic process GO:0046500 1 0.264
regulation of nucleic acid templated transcription GO:1903506 213 0.251
regulation of primary metabolic process GO:0080090 311 0.212
cell surface receptor signaling pathway GO:0007166 325 0.211
modification dependent protein catabolic process GO:0019941 3 0.201
cell projection organization GO:0030030 284 0.196
vasculature development GO:0001944 278 0.191
digestive tract development GO:0048565 265 0.189
organic acid metabolic process GO:0006082 31 0.180
cellular protein modification process GO:0006464 100 0.173
cellular macromolecule metabolic process GO:0044260 391 0.172
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.164
regulation of gene expression GO:0010468 265 0.164
biosynthetic process GO:0009058 294 0.154
organic cyclic compound biosynthetic process GO:1901362 223 0.152
organic cyclic compound metabolic process GO:1901360 301 0.146
carboxylic acid metabolic process GO:0019752 22 0.139
nitrogen compound metabolic process GO:0006807 319 0.138
heterocycle biosynthetic process GO:0018130 215 0.126
cell adhesion GO:0007155 40 0.123
biological adhesion GO:0022610 40 0.118
macromolecule biosynthetic process GO:0009059 227 0.116
gastrulation GO:0007369 208 0.114
hepaticobiliary system development GO:0061008 98 0.114
rna metabolic process GO:0016070 219 0.113
nucleobase containing compound metabolic process GO:0006139 274 0.108
regulation of rna biosynthetic process GO:2001141 213 0.101
small molecule metabolic process GO:0044281 77 0.093
organic substance biosynthetic process GO:1901576 289 0.093
very long chain fatty acid biosynthetic process GO:0042761 4 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.086
regulation of rna metabolic process GO:0051252 224 0.085
adherens junction organization GO:0034332 4 0.085
regulation of stem cell proliferation GO:0072091 2 0.085
nucleic acid metabolic process GO:0090304 244 0.082
single fertilization GO:0007338 3 0.082
single organism metabolic process GO:0044710 217 0.081
cellular component assembly GO:0022607 170 0.080
transcription dna templated GO:0006351 181 0.078
heterocycle metabolic process GO:0046483 290 0.077
cellular response to extracellular stimulus GO:0031668 2 0.077
digestive system development GO:0055123 289 0.076
heart looping GO:0001947 94 0.072
regulation of metabolic process GO:0019222 359 0.071
regulation of transcription dna templated GO:0006355 213 0.067
cellular nitrogen compound metabolic process GO:0034641 290 0.065
regulation of cellular metabolic process GO:0031323 320 0.062
blood circulation GO:0008015 87 0.062
regulation of macromolecule metabolic process GO:0060255 317 0.061
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.059
aromatic compound biosynthetic process GO:0019438 217 0.058
signal transduction GO:0007165 455 0.058
cellular protein metabolic process GO:0044267 129 0.056
cell junction organization GO:0034330 11 0.055
regulation of multicellular organismal process GO:0051239 277 0.054
heart morphogenesis GO:0003007 156 0.053
innervation GO:0060384 3 0.053
larval development GO:0002164 2 0.052
regulation of macromolecule biosynthetic process GO:0010556 225 0.050
morphogenesis of an epithelium GO:0002009 333 0.050
regulation of cellular ketone metabolic process GO:0010565 7 0.050
neuron projection morphogenesis GO:0048812 161 0.049
protein modification process GO:0036211 100 0.048
cell death GO:0008219 121 0.048
muscle cell differentiation GO:0042692 139 0.048
establishment of cell polarity involved in mesendodermal cell migration GO:0003369 1 0.046
endoderm development GO:0007492 49 0.046
regulation of embryonic development GO:0045995 47 0.046
cellular modified amino acid metabolic process GO:0006575 3 0.046
cell morphogenesis GO:0000902 289 0.046
cellular amino acid metabolic process GO:0006520 7 0.046
rna biosynthetic process GO:0032774 181 0.045
regulation of biosynthetic process GO:0009889 250 0.045
long chain fatty acid metabolic process GO:0001676 1 0.045
cellular biosynthetic process GO:0044249 286 0.044
generation of neurons GO:0048699 385 0.044
regulation of cytoplasmic transport GO:1903649 4 0.044
macromolecule modification GO:0043412 111 0.042
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.042
neuron projection development GO:0031175 180 0.041
cell part morphogenesis GO:0032990 246 0.041
protein metabolic process GO:0019538 183 0.041
eye development GO:0001654 277 0.041
blood vessel morphogenesis GO:0048514 216 0.041
fatty acid elongation GO:0030497 1 0.041
organelle localization GO:0051640 49 0.040
digestive tract morphogenesis GO:0048546 231 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
transcription from rna polymerase ii promoter GO:0006366 80 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
cellular carbohydrate metabolic process GO:0044262 4 0.038
cell cell junction organization GO:0045216 10 0.038
nucleocytoplasmic transport GO:0006913 4 0.038
epithelial cell morphogenesis GO:0003382 2 0.037
regulation of cellular biosynthetic process GO:0031326 245 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
long chain fatty acid biosynthetic process GO:0042759 1 0.034
regulation of dna templated transcription in response to stress GO:0043620 0 0.034
cellular component biogenesis GO:0044085 178 0.033
positive regulation of cell adhesion GO:0045785 1 0.033
cellular component morphogenesis GO:0032989 336 0.033
developmental maturation GO:0021700 34 0.033
embryonic heart tube development GO:0035050 133 0.032
regulation of anatomical structure morphogenesis GO:0022603 130 0.032
erk1 and erk2 cascade GO:0070371 4 0.031
muscle cell development GO:0055001 115 0.030
circulatory system process GO:0003013 87 0.030
aging GO:0007568 2 0.029
positive regulation of macromolecule metabolic process GO:0010604 93 0.029
sensory perception GO:0007600 39 0.029
fertilization GO:0009566 3 0.028
maintenance of location GO:0051235 4 0.028
regulation of carbohydrate metabolic process GO:0006109 4 0.028
negative regulation of protein kinase activity GO:0006469 4 0.028
cell migration GO:0016477 237 0.028
nucleic acid templated transcription GO:0097659 181 0.028
blood vessel development GO:0001568 246 0.028
macromolecular complex disassembly GO:0032984 1 0.027
positive regulation of rna biosynthetic process GO:1902680 57 0.027
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.027
regulation of glucose transport GO:0010827 1 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.026
cellular response to external stimulus GO:0071496 2 0.026
nuclear migration GO:0007097 3 0.026
regulation of organ growth GO:0046620 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
regionalization GO:0003002 274 0.024
positive regulation of translation GO:0045727 1 0.024
cellular response to starvation GO:0009267 1 0.024
neuron differentiation GO:0030182 353 0.024
system process GO:0003008 185 0.023
cardiac muscle tissue development GO:0048738 48 0.023
chordate embryonic development GO:0043009 271 0.023
cellular ketone metabolic process GO:0042180 11 0.023
cell projection morphogenesis GO:0048858 244 0.022
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.022
determination of left right symmetry GO:0007368 179 0.022
regulation of blood circulation GO:1903522 32 0.022
regulation of cell matrix adhesion GO:0001952 1 0.021
positive regulation of epithelial cell migration GO:0010634 2 0.021
protein acetylation GO:0006473 2 0.021
tight junction assembly GO:0070830 1 0.021
reproduction GO:0000003 40 0.020
regulation of cell death GO:0010941 103 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
neuron development GO:0048666 262 0.019
actin filament based process GO:0030029 64 0.019
single organism cell adhesion GO:0098602 29 0.019
regulation of protein transport GO:0051223 3 0.019
multi organism reproductive process GO:0044703 36 0.019
regulation of intracellular protein transport GO:0033157 3 0.018
cell proliferation GO:0008283 80 0.018
negative regulation of dna replication GO:0008156 2 0.018
specification of symmetry GO:0009799 204 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
anterior posterior axis specification GO:0009948 20 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of molecular function GO:0065009 70 0.018
macromolecule localization GO:0033036 54 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
protein complex disassembly GO:0043241 1 0.017
sensory organ development GO:0007423 393 0.017
adherens junction maintenance GO:0034334 2 0.017
regulation of biological quality GO:0065008 263 0.017
kupffer s vesicle development GO:0070121 50 0.017
multi organism process GO:0051704 134 0.017
regulation of metal ion transport GO:0010959 4 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.016
striated muscle cell differentiation GO:0051146 129 0.016
death GO:0016265 121 0.016
cell maturation GO:0048469 23 0.016
lipid storage GO:0019915 1 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
sensory organ morphogenesis GO:0090596 200 0.016
negative regulation of stem cell differentiation GO:2000737 2 0.015
positive regulation of biological process GO:0048518 253 0.015
endosome organization GO:0007032 2 0.015
glucocorticoid metabolic process GO:0008211 2 0.015
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
cell junction maintenance GO:0034331 2 0.014
muscle tissue development GO:0060537 110 0.014
regulation of cardiac muscle tissue development GO:0055024 1 0.014
detection of stimulus GO:0051606 29 0.014
establishment of organelle localization GO:0051656 45 0.014
regulation of organ morphogenesis GO:2000027 35 0.014
organelle assembly GO:0070925 110 0.014
action potential GO:0001508 19 0.013
convergent extension GO:0060026 118 0.013
determination of bilateral symmetry GO:0009855 204 0.013
axonogenesis GO:0007409 152 0.013
golgi vesicle transport GO:0048193 3 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
response to decreased oxygen levels GO:0036293 25 0.013
vesicle localization GO:0051648 27 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.012
heart development GO:0007507 313 0.012
regulation of cell development GO:0060284 100 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
muscle structure development GO:0061061 196 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
response to chemical GO:0042221 320 0.012
response to drug GO:0042493 3 0.011
regulation of heart growth GO:0060420 2 0.011
protein import GO:0017038 3 0.011
sulfur compound metabolic process GO:0006790 13 0.011
negative regulation of biological process GO:0048519 304 0.011
endocrine hormone secretion GO:0060986 2 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of establishment of planar polarity GO:0090175 4 0.011
nuclear transport GO:0051169 4 0.011
single organismal cell cell adhesion GO:0016337 29 0.011
gland development GO:0048732 143 0.011
locomotion GO:0040011 313 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
notochord development GO:0030903 54 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
multicellular organismal water homeostasis GO:0050891 1 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
lipid biosynthetic process GO:0008610 22 0.010
regulation of blood pressure GO:0008217 1 0.010
central nervous system development GO:0007417 387 0.010
regulation of eye photoreceptor cell development GO:0042478 2 0.010
response to oxygen levels GO:0070482 25 0.010
cellular response to nutrient levels GO:0031669 2 0.010

tjp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.070
muscular disease DOID:0080000 0 0.070
heart disease DOID:114 0 0.070
cardiomyopathy DOID:0050700 0 0.070
disease of anatomical entity DOID:7 0 0.070
intrinsic cardiomyopathy DOID:0060036 0 0.070
cardiovascular system disease DOID:1287 0 0.070
musculoskeletal system disease DOID:17 0 0.070
muscle tissue disease DOID:66 0 0.070
disease of mental health DOID:150 0 0.024
developmental disorder of mental health DOID:0060037 0 0.024
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
connective tissue disease DOID:65 0 0.011