Danio rerio

22 known processes

rab8b

RAB8B, member RAS oncogene family

(Aliases: zgc:165529)

rab8b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.070
aging GO:0007568 2 0.064
cell surface receptor signaling pathway GO:0007166 325 0.064
head development GO:0060322 303 0.059
sensory organ development GO:0007423 393 0.054
neuron differentiation GO:0030182 353 0.053
regulation of developmental process GO:0050793 247 0.045
central nervous system development GO:0007417 387 0.045
positive regulation of transport GO:0051050 2 0.045
heart development GO:0007507 313 0.045
cellular macromolecule metabolic process GO:0044260 391 0.044
signal transduction GO:0007165 455 0.043
regulation of muscle contraction GO:0006937 3 0.042
response to carbohydrate GO:0009743 3 0.042
response to chemical GO:0042221 320 0.040
regulation of metabolic process GO:0019222 359 0.038
brain development GO:0007420 293 0.037
cellular component movement GO:0006928 335 0.036
cellular component assembly GO:0022607 170 0.036
regulation of cellular metabolic process GO:0031323 320 0.036
cell part morphogenesis GO:0032990 246 0.035
amine metabolic process GO:0009308 2 0.035
regulation of protein transport GO:0051223 3 0.034
gene expression GO:0010467 252 0.034
regulation of macromolecule metabolic process GO:0060255 317 0.034
regulation of signal transduction GO:0009966 225 0.034
cellular amine metabolic process GO:0044106 2 0.034
multicellular organism growth GO:0035264 4 0.033
maintenance of location GO:0051235 4 0.033
organelle organization GO:0006996 227 0.033
stem cell maintenance GO:0019827 4 0.033
cellular component morphogenesis GO:0032989 336 0.032
generation of neurons GO:0048699 385 0.032
protein metabolic process GO:0019538 183 0.032
localization of cell GO:0051674 244 0.032
positive regulation of map kinase activity GO:0043406 3 0.032
regulation of primary metabolic process GO:0080090 311 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.031
negative regulation of cellular process GO:0048523 283 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
regionalization GO:0003002 274 0.030
regulation of cell communication GO:0010646 232 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.029
heterocycle metabolic process GO:0046483 290 0.029
regulation of metal ion transport GO:0010959 4 0.029
compound eye development GO:0048749 2 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
regulation of cell shape GO:0008360 1 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
cellular protein catabolic process GO:0044257 4 0.027
establishment of localization GO:0051234 244 0.027
response to monosaccharide GO:0034284 3 0.027
embryonic organ development GO:0048568 381 0.027
regulation of cell development GO:0060284 100 0.027
biosynthetic process GO:0009058 294 0.027
blood vessel development GO:0001568 246 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
regulation of protein complex assembly GO:0043254 3 0.026
cell motility GO:0048870 244 0.026
mitochondrion organization GO:0007005 4 0.026
stem cell proliferation GO:0072089 4 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
transcription dna templated GO:0006351 181 0.026
cell projection organization GO:0030030 284 0.026
cell migration GO:0016477 237 0.026
regulation of biological quality GO:0065008 263 0.026
notochord development GO:0030903 54 0.026
regulation of response to stimulus GO:0048583 269 0.025
response to hexose GO:0009746 3 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
development of primary female sexual characteristics GO:0046545 4 0.025
negative regulation of biological process GO:0048519 304 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
neurotransmitter transport GO:0006836 2 0.025
locomotion GO:0040011 313 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
cellular response to external stimulus GO:0071496 2 0.024
lipid storage GO:0019915 1 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
response to drug GO:0042493 3 0.024
regulation of ion transmembrane transporter activity GO:0032412 2 0.024
regulation of mrna processing GO:0050684 3 0.024
neuron development GO:0048666 262 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
regulation of rna metabolic process GO:0051252 224 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
positive regulation of cell cycle GO:0045787 3 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
intracellular signal transduction GO:0035556 85 0.024
response to organic substance GO:0010033 153 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
nucleic acid templated transcription GO:0097659 181 0.024
synaptic transmission cholinergic GO:0007271 4 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
positive regulation of catabolic process GO:0009896 4 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
cellular component biogenesis GO:0044085 178 0.023
single organism transport GO:0044765 206 0.023
nuclear transport GO:0051169 4 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
response to external stimulus GO:0009605 264 0.022
cell morphogenesis GO:0000902 289 0.022
regulation of synapse organization GO:0050807 3 0.022
autophagy GO:0006914 4 0.022
forebrain cell migration GO:0021885 1 0.022
rna metabolic process GO:0016070 219 0.022
nucleic acid metabolic process GO:0090304 244 0.022
system process GO:0003008 185 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
eye development GO:0001654 277 0.021
gland development GO:0048732 143 0.021
post embryonic organ development GO:0048569 4 0.021
cognition GO:0050890 1 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
neuroblast proliferation GO:0007405 2 0.021
cellular ketone metabolic process GO:0042180 11 0.021
blood vessel morphogenesis GO:0048514 216 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
regulation of cytokine production GO:0001817 3 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of binding GO:0051098 3 0.021
transport GO:0006810 220 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
somatic muscle development GO:0007525 4 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
regulation of synapse assembly GO:0051963 3 0.020
lateral inhibition GO:0046331 1 0.020
regulation of transporter activity GO:0032409 2 0.020
camera type eye development GO:0043010 222 0.020
positive regulation of cellular process GO:0048522 201 0.020
cellular response to starvation GO:0009267 1 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
smooth muscle contraction GO:0006939 2 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
cell substrate adhesion GO:0031589 4 0.020
female sex differentiation GO:0046660 4 0.019
hemopoiesis GO:0030097 183 0.019
response to stress GO:0006950 263 0.019
positive regulation of biological process GO:0048518 253 0.019
circulatory system process GO:0003013 87 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
determination of left right symmetry GO:0007368 179 0.019
endosomal transport GO:0016197 2 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
single organism organelle organization GO:1902589 199 0.019
protein secretion GO:0009306 1 0.019
protein acetylation GO:0006473 2 0.019
protein dephosphorylation GO:0006470 3 0.019
angiogenesis GO:0001525 158 0.019
leukocyte proliferation GO:0070661 1 0.018
protein localization to plasma membrane GO:0072659 1 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
meiotic nuclear division GO:0007126 4 0.018
b cell activation GO:0042113 2 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
organic acid metabolic process GO:0006082 31 0.018
specification of symmetry GO:0009799 204 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
tube morphogenesis GO:0035239 349 0.018
determination of bilateral symmetry GO:0009855 204 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
protein localization to nucleus GO:0034504 3 0.018
adherens junction organization GO:0034332 4 0.018
regulation of cell activation GO:0050865 1 0.018
cellular protein metabolic process GO:0044267 129 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
organic substance biosynthetic process GO:1901576 289 0.018
cranial ganglion development GO:0061550 3 0.018
digestive system development GO:0055123 289 0.018
cellular response to organic substance GO:0071310 105 0.018
protein import into nucleus GO:0006606 3 0.018
regulation of cell differentiation GO:0045595 142 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
rna biosynthetic process GO:0032774 181 0.017
ear development GO:0043583 127 0.017
single organism localization GO:1902578 225 0.017
positive regulation of secretion GO:0051047 1 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
negative regulation of cell death GO:0060548 60 0.017
cellular component disassembly GO:0022411 1 0.017
regulation of reproductive process GO:2000241 4 0.017
sequestering of metal ion GO:0051238 3 0.017
microtubule organizing center organization GO:0031023 1 0.017
regulation of autophagy GO:0010506 3 0.017
cell matrix adhesion GO:0007160 4 0.017
immune system development GO:0002520 191 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
vasculature development GO:0001944 278 0.017
regulation of apoptotic process GO:0042981 98 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
mononuclear cell proliferation GO:0032943 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
regulation of programmed cell death GO:0043067 101 0.017
spermatid development GO:0007286 2 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
regulation of blood pressure GO:0008217 1 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
regulation of signaling GO:0023051 235 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
cell fate specification GO:0001708 68 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
phagocytosis GO:0006909 3 0.016
exocytosis GO:0006887 1 0.016
anterior posterior pattern specification GO:0009952 152 0.016
heart contraction GO:0060047 71 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
gtp catabolic process GO:0006184 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of gene expression GO:0010468 265 0.016
signal transduction in absence of ligand GO:0038034 1 0.015
rna localization GO:0006403 4 0.015
small molecule metabolic process GO:0044281 77 0.015
antimicrobial humoral response GO:0019730 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
sensory perception of pain GO:0019233 1 0.015
heart morphogenesis GO:0003007 156 0.015
muscle cell development GO:0055001 115 0.015
muscle tissue development GO:0060537 110 0.015
blood circulation GO:0008015 87 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
response to glucose GO:0009749 3 0.015
regulation of sodium ion transport GO:0002028 2 0.015
actin filament based movement GO:0030048 1 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of striated muscle contraction GO:0006942 2 0.015
nuclear import GO:0051170 3 0.015
regulation of blood vessel size GO:0050880 2 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
immune system process GO:0002376 241 0.015
inner ear development GO:0048839 126 0.015
cytosolic calcium ion transport GO:0060401 3 0.014
neuron projection development GO:0031175 180 0.014
female gonad development GO:0008585 4 0.014
regulation of transcription dna templated GO:0006355 213 0.014
regulation of calcium ion transport GO:0051924 2 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
chemosensory behavior GO:0007635 1 0.014
lateral line system development GO:0048925 76 0.014
multicellular organismal signaling GO:0035637 22 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
centrosome organization GO:0051297 1 0.014
cellular localization GO:0051641 97 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
regulation of biosynthetic process GO:0009889 250 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
protein import GO:0017038 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
spermatid differentiation GO:0048515 2 0.014
axon development GO:0061564 166 0.014
sensory organ morphogenesis GO:0090596 200 0.014
cellular protein modification process GO:0006464 100 0.014
homeostatic process GO:0042592 142 0.014
regulation of system process GO:0044057 40 0.014
sequestering of calcium ion GO:0051208 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
gtp metabolic process GO:0046039 4 0.014
apoptotic process GO:0006915 116 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
response to nutrient GO:0007584 3 0.014
cell death GO:0008219 121 0.014
neuron projection morphogenesis GO:0048812 161 0.014
sprouting angiogenesis GO:0002040 53 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of meiotic cell cycle GO:0051445 1 0.013
germ line stem cell maintenance GO:0030718 2 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
cell fate commitment GO:0045165 99 0.013
retina development in camera type eye GO:0060041 146 0.013
adult behavior GO:0030534 2 0.013
amino acid transport GO:0006865 2 0.013
muscle organ development GO:0007517 101 0.013
startle response GO:0001964 4 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
monoamine transport GO:0015844 1 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
activation of mapk activity GO:0000187 3 0.013
stem cell division GO:0017145 1 0.013
digestive tract morphogenesis GO:0048546 231 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
actin mediated cell contraction GO:0070252 1 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
regulation of cellular component organization GO:0051128 86 0.013
heart process GO:0003015 71 0.013
negative regulation of cell communication GO:0010648 96 0.013
macromolecular complex disassembly GO:0032984 1 0.013
peptide transport GO:0015833 1 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
hormone transport GO:0009914 2 0.013
ameboidal type cell migration GO:0001667 143 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
outflow tract morphogenesis GO:0003151 1 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
negative regulation of response to stimulus GO:0048585 104 0.012
single organism nuclear import GO:1902593 3 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
protein acylation GO:0043543 3 0.012
protein complex disassembly GO:0043241 1 0.012
phagocytosis engulfment GO:0006911 1 0.012
positive regulation of translation GO:0045727 1 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
digestive tract development GO:0048565 265 0.012
neuronal action potential GO:0019228 18 0.012
growth GO:0040007 174 0.012
response to endogenous stimulus GO:0009719 83 0.012
programmed cell death GO:0012501 119 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
response to uv GO:0009411 3 0.012
protein polymerization GO:0051258 4 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
positive regulation of cytokine production GO:0001819 2 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
membrane invagination GO:0010324 1 0.012
actin filament polymerization GO:0030041 2 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
inner ear morphogenesis GO:0042472 63 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
cellular amide metabolic process GO:0043603 4 0.012
transmembrane transport GO:0055085 120 0.012
regulation of neurogenesis GO:0050767 87 0.012
skeletal muscle organ development GO:0060538 78 0.012
neurological system process GO:0050877 62 0.012
embryonic heart tube development GO:0035050 133 0.012
neurotransmitter secretion GO:0007269 2 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
action potential GO:0001508 19 0.012
connective tissue development GO:0061448 99 0.011
developmental growth GO:0048589 166 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
neuromast development GO:0048884 46 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
ion transmembrane transport GO:0034220 91 0.011
muscle structure development GO:0061061 196 0.011
negative regulation of protein transport GO:0051224 3 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of heart contraction GO:0008016 32 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
negative regulation of developmental process GO:0051093 65 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
multi organism process GO:0051704 134 0.011
regulation of cardiac muscle contraction GO:0055117 2 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
positive regulation of multi organism process GO:0043902 3 0.011
regulation of dna replication GO:0006275 3 0.011
protein targeting to nucleus GO:0044744 3 0.011
response to abiotic stimulus GO:0009628 122 0.011
embryonic skeletal system development GO:0048706 97 0.011
cell projection morphogenesis GO:0048858 244 0.011
regulation of nervous system development GO:0051960 90 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
primary neural tube formation GO:0014020 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
peptidyl threonine modification GO:0018210 1 0.011
nuclear export GO:0051168 1 0.011
rna 3 end processing GO:0031123 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
skin development GO:0043588 54 0.011
protein modification process GO:0036211 100 0.011
cytokinesis GO:0000910 3 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
sympathetic nervous system development GO:0048485 3 0.011
eye morphogenesis GO:0048592 144 0.011
response to wounding GO:0009611 116 0.011
regulation of protein targeting GO:1903533 2 0.011
ion transport GO:0006811 114 0.011
stem cell fate commitment GO:0048865 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
photoreceptor cell fate specification GO:0043704 1 0.011
axonogenesis GO:0007409 152 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
photoreceptor cell fate commitment GO:0046552 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
response to amino acid GO:0043200 2 0.010
b cell differentiation GO:0030183 1 0.010
ear morphogenesis GO:0042471 64 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
carbohydrate homeostasis GO:0033500 1 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010
sensory system development GO:0048880 76 0.010
synaptic vesicle transport GO:0048489 1 0.010
regulation of protein polymerization GO:0032271 2 0.010
membrane fusion GO:0061025 2 0.010
macromolecule modification GO:0043412 111 0.010
mesenchyme development GO:0060485 127 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
atp catabolic process GO:0006200 4 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
cytoskeleton organization GO:0007010 96 0.010
glucose homeostasis GO:0042593 1 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
regulation of protein binding GO:0043393 3 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010

rab8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
cardiovascular system disease DOID:1287 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011