Danio rerio

67 known processes

hdac4

histone deacetylase 4

(Aliases: KIAA0288,wu:fc56f08,zgc:152701,wu:fa96d08)

hdac4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 0.526
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.445
regulation of nitrogen compound metabolic process GO:0051171 251 0.431
Human Mouse Worm Fly
regulation of cellular response to growth factor stimulus GO:0090287 35 0.403
response to growth factor GO:0070848 39 0.395
regulation of cell communication GO:0010646 232 0.384
cellular response to growth factor stimulus GO:0071363 39 0.378
regulation of multicellular organismal development GO:2000026 223 0.353
growth GO:0040007 174 0.332
Worm
regulation of developmental process GO:0050793 247 0.307
eye development GO:0001654 277 0.306
enzyme linked receptor protein signaling pathway GO:0007167 106 0.296
larval development GO:0002164 2 0.274
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.269
regulation of biological quality GO:0065008 263 0.265
regulation of transcription dna templated GO:0006355 213 0.261
Human Mouse Worm Fly
cellular response to chemical stimulus GO:0070887 157 0.261
cellular macromolecule biosynthetic process GO:0034645 224 0.251
Human Mouse Worm Fly
protein targeting to nucleus GO:0044744 3 0.245
cellular component movement GO:0006928 335 0.224
cellular protein metabolic process GO:0044267 129 0.213
Human Mouse Fly
negative regulation of signal transduction GO:0009968 94 0.205
cell projection organization GO:0030030 284 0.195
regulation of response to stimulus GO:0048583 269 0.183
Mouse
central nervous system development GO:0007417 387 0.182
establishment of protein localization to organelle GO:0072594 4 0.174
protein import into nucleus GO:0006606 3 0.173
macromolecule biosynthetic process GO:0009059 227 0.170
Human Mouse Worm Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.168
developmental growth GO:0048589 166 0.160
regulation of rna biosynthetic process GO:2001141 213 0.158
Human Mouse Worm Fly
protein import GO:0017038 3 0.156
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.154
locomotion GO:0040011 313 0.152
single organism localization GO:1902578 225 0.149
maintenance of location GO:0051235 4 0.148
hypothalamus cell differentiation GO:0021979 4 0.146
aging GO:0007568 2 0.146
single organism nuclear import GO:1902593 3 0.145
negative regulation of cell communication GO:0010648 96 0.140
regulation of stem cell differentiation GO:2000736 4 0.139
erk1 and erk2 cascade GO:0070371 4 0.139
branchiomotor neuron axon guidance GO:0021785 1 0.131
small gtpase mediated signal transduction GO:0007264 8 0.129
camera type eye development GO:0043010 222 0.126
mesenchymal cell development GO:0014031 78 0.124
regulation of cellular metabolic process GO:0031323 320 0.123
Human Mouse Worm Fly
autophagy GO:0006914 4 0.122
urogenital system development GO:0001655 97 0.120
apoptotic process GO:0006915 116 0.119
regulation of signaling GO:0023051 235 0.115
positive regulation of transcription dna templated GO:0045893 57 0.114
Human Mouse
stem cell differentiation GO:0048863 117 0.114
forebrain cell migration GO:0021885 1 0.113
skeletal system morphogenesis GO:0048705 102 0.113
pigment cell differentiation GO:0050931 38 0.112
heterocycle biosynthetic process GO:0018130 215 0.112
Human Mouse Worm Fly
regulation of binding GO:0051098 3 0.109
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.109
Human Mouse Worm Fly
negative regulation of biological process GO:0048519 304 0.108
Human Mouse Worm
lipid storage GO:0019915 1 0.106
multicellular organism growth GO:0035264 4 0.106
negative regulation of bmp signaling pathway GO:0030514 13 0.105
cellular macromolecule metabolic process GO:0044260 391 0.105
Human Mouse Worm Fly
bmp signaling pathway GO:0030509 52 0.104
connective tissue development GO:0061448 99 0.103
regionalization GO:0003002 274 0.102
signal transduction GO:0007165 455 0.102
Mouse
regulation of autophagy GO:0010506 3 0.101
embryonic organ development GO:0048568 381 0.100
regulation of synaptic vesicle transport GO:1902803 1 0.099
sprouting angiogenesis GO:0002040 53 0.099
cellular response to organic substance GO:0071310 105 0.097
heterocycle metabolic process GO:0046483 290 0.097
Human Mouse Worm Fly
regulation of protein targeting GO:1903533 2 0.096
cell motility GO:0048870 244 0.096
digestive system development GO:0055123 289 0.096
regulation of signal transduction GO:0009966 225 0.095
nuclear import GO:0051170 3 0.094
protein secretion GO:0009306 1 0.093
regulation of skeletal muscle fiber development GO:0048742 2 0.092
Mouse
response to chemical GO:0042221 320 0.092
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.091
regulation of biosynthetic process GO:0009889 250 0.091
Human Mouse Worm Fly
ameboidal type cell migration GO:0001667 143 0.091
localization of cell GO:0051674 244 0.089
regulation of chondrocyte differentiation GO:0032330 1 0.088
blood vessel endothelial cell migration GO:0043534 18 0.088
regulation of response to cytokine stimulus GO:0060759 3 0.088
cellular nitrogen compound metabolic process GO:0034641 290 0.088
Human Mouse Worm Fly
sympathetic ganglion development GO:0061549 2 0.087
negative regulation of response to stimulus GO:0048585 104 0.087
regulation of primary metabolic process GO:0080090 311 0.087
Human Mouse Worm Fly
odontogenesis of dentin containing tooth GO:0042475 1 0.086
transcription dna templated GO:0006351 181 0.085
Human Mouse Worm Fly
regulation of erk1 and erk2 cascade GO:0070372 4 0.084
neuron projection development GO:0031175 180 0.084
taxis GO:0042330 109 0.083
response to wounding GO:0009611 116 0.082
protein localization to nucleus GO:0034504 3 0.082
cellular nitrogen compound biosynthetic process GO:0044271 218 0.081
Human Mouse Worm Fly
segmentation GO:0035282 97 0.080
female gonad development GO:0008585 4 0.080
developmental cell growth GO:0048588 52 0.079
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.079
regulation of multicellular organism growth GO:0040014 4 0.079
regulation of cell differentiation GO:0045595 142 0.078
regulation of cytoplasmic transport GO:1903649 4 0.077
tube morphogenesis GO:0035239 349 0.077
central nervous system neuron differentiation GO:0021953 74 0.077
nucleic acid templated transcription GO:0097659 181 0.077
Human Mouse Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.073
negative regulation of autophagy GO:0010507 1 0.073
chemotaxis GO:0006935 104 0.072
nitrogen compound metabolic process GO:0006807 319 0.072
Human Mouse Worm Fly
response to carbohydrate GO:0009743 3 0.072
chordate embryonic development GO:0043009 271 0.072
protein modification process GO:0036211 100 0.071
Human Mouse Fly
developmental growth involved in morphogenesis GO:0060560 86 0.070
nuclear transport GO:0051169 4 0.070
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.070
organic substance biosynthetic process GO:1901576 289 0.070
Human Mouse Worm Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.070
axon guidance GO:0007411 86 0.070
positive regulation of secretion by cell GO:1903532 1 0.069
sleep GO:0030431 1 0.069
regulation of dna replication GO:0006275 3 0.069
motor neuron axon guidance GO:0008045 23 0.069
positive regulation of cell cycle GO:0045787 3 0.068
response to ketone GO:1901654 1 0.068
positive regulation of secretion GO:0051047 1 0.067
muscle fiber development GO:0048747 52 0.067
Mouse
regulation of postsynaptic membrane potential GO:0060078 1 0.066
embryo development ending in birth or egg hatching GO:0009792 271 0.065
stem cell development GO:0048864 82 0.064
cellular biosynthetic process GO:0044249 286 0.064
Human Mouse Worm Fly
cartilage development GO:0051216 96 0.063
regulation of reactive oxygen species metabolic process GO:2000377 2 0.063
somitogenesis GO:0001756 87 0.062
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.062
Human
sensory organ morphogenesis GO:0090596 200 0.062
vascular endothelial growth factor signaling pathway GO:0038084 3 0.062
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.061
Human Mouse Worm Fly
cell growth GO:0016049 57 0.060
establishment of localization GO:0051234 244 0.060
carbohydrate derivative metabolic process GO:1901135 61 0.060
intrahepatic bile duct development GO:0035622 11 0.060
retinoic acid receptor signaling pathway GO:0048384 16 0.059
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.058
neuron projection guidance GO:0097485 86 0.058
renal system development GO:0072001 94 0.058
cellular ketone metabolic process GO:0042180 11 0.058
cell projection morphogenesis GO:0048858 244 0.058
negative regulation of developmental process GO:0051093 65 0.057
Human Mouse
behavior GO:0007610 74 0.057
Fly
single organism metabolic process GO:0044710 217 0.057
Human Mouse Fly
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.056
regulation of cytokine mediated signaling pathway GO:0001959 3 0.055
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.055
negative regulation of chemotaxis GO:0050922 4 0.055
phosphorylation GO:0016310 69 0.054
embryonic skeletal system development GO:0048706 97 0.053
positive regulation of rna biosynthetic process GO:1902680 57 0.053
Human Mouse
negative regulation of cell differentiation GO:0045596 46 0.053
Human Mouse
head development GO:0060322 303 0.053
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.053
negative regulation of protein phosphorylation GO:0001933 4 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.052
Human Mouse
regulation of protein transport GO:0051223 3 0.052
cranial ganglion development GO:0061550 3 0.051
regulation of establishment of protein localization GO:0070201 4 0.051
phagocytosis GO:0006909 3 0.051
macromolecule modification GO:0043412 111 0.051
Human Mouse Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.050
positive regulation of biological process GO:0048518 253 0.050
Human Mouse
negative regulation of axon guidance GO:1902668 1 0.050
regulation of rna metabolic process GO:0051252 224 0.050
Human Mouse Worm Fly
negative regulation of response to cytokine stimulus GO:0060761 2 0.050
aromatic compound biosynthetic process GO:0019438 217 0.049
Human Mouse Worm Fly
circadian sleep wake cycle process GO:0022410 2 0.049
immune system development GO:0002520 191 0.049
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.048
regulation of cell activation GO:0050865 1 0.048
gastrulation GO:0007369 208 0.047
chromosome organization involved in meiosis GO:0070192 1 0.047
biosynthetic process GO:0009058 294 0.046
Human Mouse Worm Fly
multi organism cellular process GO:0044764 2 0.046
trigeminal nerve development GO:0021559 3 0.046
transmission of nerve impulse GO:0019226 19 0.046
intracellular signal transduction GO:0035556 85 0.046
Mouse
cell part morphogenesis GO:0032990 246 0.045
gland development GO:0048732 143 0.045
nucleic acid metabolic process GO:0090304 244 0.045
Human Mouse Worm Fly
eye morphogenesis GO:0048592 144 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.044
negative regulation of cellular process GO:0048523 283 0.044
Human Mouse Worm
cell substrate adhesion GO:0031589 4 0.044
regulation of cellular biosynthetic process GO:0031326 245 0.043
Human Mouse Worm Fly
determination of heart left right asymmetry GO:0061371 117 0.042
reactive oxygen species metabolic process GO:0072593 6 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.042
Human Mouse Worm Fly
regulation of oligodendrocyte differentiation GO:0048713 1 0.042
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.042
dorsal ventral pattern formation GO:0009953 125 0.042
phosphorus metabolic process GO:0006793 109 0.041
organic acid metabolic process GO:0006082 31 0.041
Mouse
positive regulation of chromatin modification GO:1903310 1 0.041
protein metabolic process GO:0019538 183 0.040
Human Mouse Fly
post embryonic organ development GO:0048569 4 0.040
regulation of multicellular organismal process GO:0051239 277 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
Human Mouse Worm Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.040
negative regulation of signaling GO:0023057 96 0.039
organic cyclic compound biosynthetic process GO:1901362 223 0.039
Human Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.039
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.039
limbic system development GO:0021761 16 0.039
cell migration GO:0016477 237 0.039
multi organism process GO:0051704 134 0.039
otic vesicle development GO:0071599 42 0.039
negative regulation of metabolic process GO:0009892 86 0.039
Human Mouse Worm
negative regulation of multicellular organismal process GO:0051241 69 0.038
Mouse
regulation of embryonic development GO:0045995 47 0.038
neuron neuron synaptic transmission GO:0007270 1 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
response to organic substance GO:0010033 153 0.038
Human
regulation of synapse organization GO:0050807 3 0.038
interspecies interaction between organisms GO:0044419 4 0.038
positive regulation of cell activation GO:0050867 1 0.037
immune response GO:0006955 28 0.037
negative regulation of synapse assembly GO:0051964 2 0.037
positive regulation of transport GO:0051050 2 0.037
innervation GO:0060384 3 0.036
phosphate containing compound metabolic process GO:0006796 108 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.036
Human Mouse
cell death GO:0008219 121 0.036
regulation of protein catabolic process GO:0042176 1 0.035
carboxylic acid metabolic process GO:0019752 22 0.035
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.035
response to alkaloid GO:0043279 2 0.035
regulation of rho protein signal transduction GO:0035023 2 0.035
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.035
establishment of localization in cell GO:0051649 77 0.035
ear development GO:0043583 127 0.034
zymogen activation GO:0031638 3 0.034
response to corticosteroid GO:0031960 1 0.034
axon extension involved in axon guidance GO:0048846 10 0.033
forebrain development GO:0030900 96 0.033
positive regulation of cellular metabolic process GO:0031325 94 0.033
Human Mouse
regulation of protein localization to nucleus GO:1900180 2 0.032
peptidyl serine phosphorylation GO:0018105 1 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.032
cell morphogenesis GO:0000902 289 0.032
single organism transport GO:0044765 206 0.031
periodic partitioning GO:0007365 1 0.031
antimicrobial humoral response GO:0019730 2 0.031
ras protein signal transduction GO:0007265 7 0.031
sensory neuron axon guidance GO:0097374 3 0.031
angiogenesis GO:0001525 158 0.031
regulation of apoptotic process GO:0042981 98 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
cellular amino acid metabolic process GO:0006520 7 0.031
hormone transport GO:0009914 2 0.031
kidney development GO:0001822 92 0.031
cognition GO:0050890 1 0.031
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
cellular response to nutrient levels GO:0031669 2 0.031
transport GO:0006810 220 0.031
positive regulation of protein complex assembly GO:0031334 2 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
Human Mouse Worm Fly
endoderm development GO:0007492 49 0.030
axon extension GO:0048675 45 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
programmed cell death GO:0012501 119 0.030
viral process GO:0016032 1 0.030
oxoacid metabolic process GO:0043436 31 0.030
Mouse
regulation of protein import into nucleus GO:0042306 2 0.030
regulation of reproductive process GO:2000241 4 0.029
female sex differentiation GO:0046660 4 0.029
developmental pigmentation GO:0048066 48 0.029
muscle structure development GO:0061061 196 0.029
Human Mouse
regulation of nervous system development GO:0051960 90 0.029
Worm
rna biosynthetic process GO:0032774 181 0.029
Human Mouse Worm Fly
larval heart development GO:0007508 2 0.029
central nervous system projection neuron axonogenesis GO:0021952 15 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.029
positive regulation of dna metabolic process GO:0051054 1 0.029
cardioblast migration GO:0003260 7 0.028
circadian sleep wake cycle sleep GO:0050802 1 0.028
exocytosis GO:0006887 1 0.028
regulation of cell size GO:0008361 29 0.028
regulation of histone methylation GO:0031060 3 0.028
regulation of bmp signaling pathway GO:0030510 39 0.028
positive regulation of muscle cell differentiation GO:0051149 1 0.028
negative chemotaxis GO:0050919 1 0.028
digestive tract development GO:0048565 265 0.028
axonal defasciculation GO:0007414 2 0.028
development of primary female sexual characteristics GO:0046545 4 0.028
circadian sleep wake cycle GO:0042745 2 0.028
protein dephosphorylation GO:0006470 3 0.028
positive regulation of cell killing GO:0031343 2 0.028
regulation of cell death GO:0010941 103 0.028
stem cell maintenance GO:0019827 4 0.028
positive regulation of developmental process GO:0051094 50 0.028
nuclear export GO:0051168 1 0.027
regulation of developmental growth GO:0048638 38 0.027
regulation of growth GO:0040008 42 0.027
positive regulation of rna metabolic process GO:0051254 59 0.027
Human Mouse
death GO:0016265 121 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
hypothalamus development GO:0021854 14 0.027
regulation of metabolic process GO:0019222 359 0.027
Human Mouse Worm Fly
rna metabolic process GO:0016070 219 0.027
Human Mouse Worm Fly
branching morphogenesis of an epithelial tube GO:0048754 15 0.027
convergent extension GO:0060026 118 0.027
neuron development GO:0048666 262 0.027
chemosensory behavior GO:0007635 1 0.027
response to hexose GO:0009746 3 0.027
mesenchymal cell differentiation GO:0048762 87 0.026
cell migration to the midline involved in heart development GO:0003318 12 0.026
hormone secretion GO:0046879 2 0.026
positive regulation of lipid metabolic process GO:0045834 1 0.026
positive regulation of muscle organ development GO:0048636 1 0.026
positive regulation of response to external stimulus GO:0032103 9 0.026
neuron differentiation GO:0030182 353 0.026
Worm
regulation of intracellular protein transport GO:0033157 3 0.026
digestive tract morphogenesis GO:0048546 231 0.026
photoreceptor cell differentiation GO:0046530 55 0.026
regulation of cellular component organization GO:0051128 86 0.026
positive regulation of ras protein signal transduction GO:0046579 1 0.026
regulation of myotube differentiation GO:0010830 2 0.026
Human Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.026
intracellular transport GO:0046907 32 0.026
cytosolic calcium ion transport GO:0060401 3 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
Human Mouse Worm Fly
response to external stimulus GO:0009605 264 0.025
positive regulation of immune effector process GO:0002699 3 0.025
regulation of neurogenesis GO:0050767 87 0.025
Worm
convergent extension involved in organogenesis GO:0060029 10 0.025
central nervous system neuron axonogenesis GO:0021955 18 0.025
camera type eye photoreceptor cell differentiation GO:0060219 19 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
Human Mouse Worm Fly
response to monosaccharide GO:0034284 3 0.025
regulation of endopeptidase activity GO:0052548 23 0.025
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.025
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
Human Mouse
cellular response to starvation GO:0009267 1 0.025
myotube cell development GO:0014904 35 0.025
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.025
thermosensory behavior GO:0040040 1 0.025
macromolecular complex subunit organization GO:0043933 74 0.025
Human Fly
positive regulation of cell division GO:0051781 2 0.025
common bile duct development GO:0061009 13 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
embryonic pattern specification GO:0009880 44 0.025
facial nerve morphogenesis GO:0021610 1 0.024
circadian regulation of gene expression GO:0032922 8 0.024
central nervous system neuron development GO:0021954 29 0.024
blood vessel development GO:0001568 246 0.024
vasculature development GO:0001944 278 0.024
camera type eye morphogenesis GO:0048593 108 0.024
gtp metabolic process GO:0046039 4 0.024
neuron migration GO:0001764 22 0.024
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.024
neural tube patterning GO:0021532 33 0.024
positive regulation of neuron projection development GO:0010976 9 0.024
heart development GO:0007507 313 0.024
negative regulation of protein kinase activity GO:0006469 4 0.023
regulation of synapse assembly GO:0051963 3 0.023
cell migration involved in gastrulation GO:0042074 79 0.023
positive regulation of dna templated transcription elongation GO:0032786 1 0.023
rna localization GO:0006403 4 0.023
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.023
regulation of cellular component size GO:0032535 30 0.023
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
Human Mouse Worm
blood circulation GO:0008015 87 0.023
Mouse
regulation of programmed cell death GO:0043067 101 0.023
regulation of dendrite morphogenesis GO:0048814 3 0.023
cellular response to biotic stimulus GO:0071216 3 0.023
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
cellular component biogenesis GO:0044085 178 0.023
mesoderm development GO:0007498 88 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.023
calcium ion transport into cytosol GO:0060402 3 0.022
regulation of protein complex assembly GO:0043254 3 0.022
regulation of neuron migration GO:2001222 2 0.022
regulation of gene expression GO:0010468 265 0.022
Human Mouse Worm Fly
actin polymerization or depolymerization GO:0008154 2 0.022
single organism organelle organization GO:1902589 199 0.022
Human Fly
neuron projection extension GO:1990138 45 0.022
modification of morphology or physiology of other organism GO:0035821 4 0.022
response to drug GO:0042493 3 0.022
photoreceptor cell development GO:0042461 40 0.022
cellular protein catabolic process GO:0044257 4 0.022
tor signaling GO:0031929 7 0.022
negative regulation of dna metabolic process GO:0051053 4 0.022
response to endogenous stimulus GO:0009719 83 0.022
otic vesicle morphogenesis GO:0071600 34 0.022
positive regulation of biosynthetic process GO:0009891 68 0.022
Human Mouse
endochondral bone growth GO:0003416 2 0.022
locomotor rhythm GO:0045475 3 0.022
protein localization GO:0008104 40 0.022
regulation of phosphorylation GO:0042325 26 0.021
regulation of hormone secretion GO:0046883 2 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cellular response to external stimulus GO:0071496 2 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.021
Human Mouse Worm
endothelial cell migration GO:0043542 19 0.021
regulation of cytokine production GO:0001817 3 0.021
regulation of locomotion GO:0040012 55 0.021
pancreas development GO:0031016 84 0.021
regulation of protein modification process GO:0031399 29 0.021
Human
response to nutrient GO:0007584 3 0.021
cellular response to hypoxia GO:0071456 1 0.021
anatomical structure arrangement GO:0048532 2 0.021
dna templated transcription elongation GO:0006354 3 0.021
negative regulation of catabolic process GO:0009895 3 0.021
Mouse
regulation of cellular component movement GO:0051270 55 0.021
chondrocyte development GO:0002063 4 0.021
multicellular organismal macromolecule metabolic process GO:0044259 2 0.021
negative regulation of locomotion GO:0040013 18 0.021
appendage development GO:0048736 80 0.021
sex determination GO:0007530 1 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
regulation of metal ion transport GO:0010959 4 0.021
regulation of localization GO:0032879 104 0.021
regulation of molecular function GO:0065009 70 0.020
Human
negative regulation of intracellular transport GO:0032387 3 0.020
response to biotic stimulus GO:0009607 97 0.020
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
regulation of system process GO:0044057 40 0.020
Mouse
neuron death GO:0070997 21 0.020
negative regulation of dna replication GO:0008156 2 0.020
sensory organ development GO:0007423 393 0.020
dendrite development GO:0016358 9 0.020
b cell activation GO:0042113 2 0.020
regulation of cell proliferation GO:0042127 37 0.020
Human Mouse
negative regulation of ras protein signal transduction GO:0046580 1 0.020
lipid catabolic process GO:0016042 4 0.020
positive regulation of multicellular organismal process GO:0051240 52 0.020
positive regulation of cell adhesion GO:0045785 1 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.019
cellular amine metabolic process GO:0044106 2 0.019
regulation of neurotransmitter secretion GO:0046928 1 0.019
adult behavior GO:0030534 2 0.019
renal tubule morphogenesis GO:0061333 1 0.019
macromolecule localization GO:0033036 54 0.019
regulation of skeletal muscle tissue development GO:0048641 4 0.019
Mouse
cellular protein modification process GO:0006464 100 0.019
Human Mouse Fly
neuron apoptotic process GO:0051402 20 0.019
regulation of protein metabolic process GO:0051246 56 0.019
Human
regulation of dendrite development GO:0050773 3 0.019
generation of neurons GO:0048699 385 0.019
Worm
positive regulation of translation GO:0045727 1 0.019
heart morphogenesis GO:0003007 156 0.019
morphogenesis of a branching epithelium GO:0061138 16 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
peptidyl serine modification GO:0018209 2 0.019
carbohydrate homeostasis GO:0033500 1 0.019
negative regulation of protein transport GO:0051224 3 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
Human Mouse Worm
otic placode formation GO:0043049 23 0.019
locomotory behavior GO:0007626 34 0.019
protein phosphorylation GO:0006468 47 0.019
positive regulation of map kinase activity GO:0043406 3 0.018
negative regulation of sequestering of calcium ion GO:0051283 4 0.018
collagen biosynthetic process GO:0032964 2 0.018
regulation of transcription involved in cell fate commitment GO:0060850 1 0.018
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.018
preganglionic parasympathetic nervous system development GO:0021783 6 0.018
chromosome organization GO:0051276 31 0.018
Human Fly
regulation of production of molecular mediator of immune response GO:0002700 1 0.018
regulation of cartilage development GO:0061035 7 0.018
cellular response to endogenous stimulus GO:0071495 68 0.018
facial nerve development GO:0021561 3 0.018
regulation of protein binding GO:0043393 3 0.018
Human
negative regulation of cellular response to growth factor stimulus GO:0090288 9 0.018
regulation of behavior GO:0050795 24 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
amine metabolic process GO:0009308 2 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
meiotic nuclear division GO:0007126 4 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
positive regulation of cell development GO:0010720 25 0.018
positive regulation of leukocyte differentiation GO:1902107 1 0.017
regulation of cell shape GO:0008360 1 0.017
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.017
negative regulation of mapk cascade GO:0043409 4 0.017

hdac4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
nervous system disease DOID:863 0 0.021