Danio rerio

0 known processes

hdac8

histone deacetylase 8

(Aliases: wu:fd19a02,zgc:66196)

hdac8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.122
heterocycle metabolic process GO:0046483 290 0.097
Yeast
regulation of macromolecule metabolic process GO:0060255 317 0.091
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.083
Yeast
regulation of gene expression GO:0010468 265 0.064
Yeast
aging GO:0007568 2 0.060
meiotic nuclear division GO:0007126 4 0.056
biosynthetic process GO:0009058 294 0.054
Yeast
regulation of metabolic process GO:0019222 359 0.053
Yeast
regulation of cellular metabolic process GO:0031323 320 0.053
Yeast
nucleocytoplasmic transport GO:0006913 4 0.051
nucleoside monophosphate catabolic process GO:0009125 4 0.051
gene expression GO:0010467 252 0.050
Yeast
regulation of primary metabolic process GO:0080090 311 0.050
Yeast
meiotic cell cycle process GO:1903046 3 0.048
cellular biosynthetic process GO:0044249 286 0.048
Yeast
negative regulation of dna metabolic process GO:0051053 4 0.044
response to external stimulus GO:0009605 264 0.043
multi organism process GO:0051704 134 0.040
maintenance of location GO:0051235 4 0.040
negative regulation of cellular metabolic process GO:0031324 77 0.039
Yeast
nucleobase containing compound biosynthetic process GO:0034654 205 0.038
Yeast
negative regulation of chromosome organization GO:2001251 1 0.038
specification of symmetry GO:0009799 204 0.036
positive regulation of biological process GO:0048518 253 0.036
Yeast
organelle organization GO:0006996 227 0.036
Yeast
negative regulation of nuclear division GO:0051784 3 0.035
multicellular organism growth GO:0035264 4 0.035
regulation of cellular amine metabolic process GO:0033238 0 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
Yeast
response to carbohydrate GO:0009743 3 0.033
cellular protein metabolic process GO:0044267 129 0.033
Yeast
regulation of signaling GO:0023051 235 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.031
rna metabolic process GO:0016070 219 0.030
Yeast
cell surface receptor signaling pathway GO:0007166 325 0.030
cell death GO:0008219 121 0.030
cellular amine metabolic process GO:0044106 2 0.029
fertilization GO:0009566 3 0.029
intracellular signal transduction GO:0035556 85 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
Yeast
regulation of response to stimulus GO:0048583 269 0.028
regulation of cell communication GO:0010646 232 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
Yeast
epithelial tube morphogenesis GO:0060562 148 0.027
single organism organelle organization GO:1902589 199 0.027
Yeast
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
cell cycle g2 m phase transition GO:0044839 4 0.026
regulation of circadian rhythm GO:0042752 4 0.025
locomotion GO:0040011 313 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
signal transduction GO:0007165 455 0.025
central nervous system development GO:0007417 387 0.025
brain development GO:0007420 293 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
Yeast
cellular response to external stimulus GO:0071496 2 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
Yeast
cellular nitrogen compound metabolic process GO:0034641 290 0.024
Yeast
cellular ketone metabolic process GO:0042180 11 0.024
single organism metabolic process GO:0044710 217 0.024
Yeast
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of autophagy GO:0010506 3 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
regulation of protein complex assembly GO:0043254 3 0.023
g2 m transition of mitotic cell cycle GO:0000086 4 0.023
protein import into nucleus GO:0006606 3 0.023
neuron differentiation GO:0030182 353 0.022
regulation of protein catabolic process GO:0042176 1 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
Yeast
cellular amino acid metabolic process GO:0006520 7 0.022
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.022
protein modification by small protein removal GO:0070646 1 0.022
positive regulation of catabolic process GO:0009896 4 0.022
regionalization GO:0003002 274 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
nucleic acid metabolic process GO:0090304 244 0.022
Yeast
sensory organ morphogenesis GO:0090596 200 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of meiotic cell cycle GO:0051445 1 0.021
amine metabolic process GO:0009308 2 0.021
negative regulation of metabolic process GO:0009892 86 0.021
Yeast
transcription dna templated GO:0006351 181 0.021
Yeast
regulation of multicellular organism growth GO:0040014 4 0.021
blood vessel development GO:0001568 246 0.021
determination of bilateral symmetry GO:0009855 204 0.021
positive regulation of cell cycle GO:0045787 3 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.020
Yeast
positive regulation of transport GO:0051050 2 0.020
embryonic organ development GO:0048568 381 0.020
protein stabilization GO:0050821 2 0.020
negative regulation of biological process GO:0048519 304 0.020
Yeast
organic acid metabolic process GO:0006082 31 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
oxoacid metabolic process GO:0043436 31 0.020
regulation of signal transduction GO:0009966 225 0.020
protein modification process GO:0036211 100 0.020
Yeast
cell motility GO:0048870 244 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
Yeast
response to monosaccharide GO:0034284 3 0.019
rna modification GO:0009451 2 0.019
small molecule metabolic process GO:0044281 77 0.019
peptide transport GO:0015833 1 0.019
regulation of cellular component organization GO:0051128 86 0.019
skin development GO:0043588 54 0.018
protein targeting to nucleus GO:0044744 3 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
response to chemical GO:0042221 320 0.018
rna biosynthetic process GO:0032774 181 0.018
Yeast
negative regulation of catabolic process GO:0009895 3 0.018
protein polymerization GO:0051258 4 0.018
negative regulation of neuron projection regeneration GO:0070571 4 0.018
regulation of biological quality GO:0065008 263 0.018
nucleic acid templated transcription GO:0097659 181 0.018
Yeast
positive regulation of cellular catabolic process GO:0031331 3 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
single organism nuclear import GO:1902593 3 0.017
developmental programmed cell death GO:0010623 4 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
response to stress GO:0006950 263 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
localization of cell GO:0051674 244 0.017
vasculature development GO:0001944 278 0.017
positive regulation of histone modification GO:0031058 1 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
nuclear transport GO:0051169 4 0.017
regulation of developmental process GO:0050793 247 0.016
growth GO:0040007 174 0.016
gtp catabolic process GO:0006184 2 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
exocytosis GO:0006887 1 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
Yeast
macromolecule modification GO:0043412 111 0.016
Yeast
autophagy GO:0006914 4 0.016
atp catabolic process GO:0006200 4 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.015
cellular component movement GO:0006928 335 0.015
liver development GO:0001889 96 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
single fertilization GO:0007338 3 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
programmed cell death GO:0012501 119 0.015
phosphorylation GO:0016310 69 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
embryonic heart tube development GO:0035050 133 0.015
apoptotic process GO:0006915 116 0.015
regulation of cell shape GO:0008360 1 0.015
single organism localization GO:1902578 225 0.015
heart development GO:0007507 313 0.015
gamete generation GO:0007276 33 0.015
multicellular organism reproduction GO:0032504 35 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
histone h3 k4 methylation GO:0051568 2 0.014
head development GO:0060322 303 0.014
generation of neurons GO:0048699 385 0.014
protein import GO:0017038 3 0.014
death GO:0016265 121 0.014
negative regulation of cellular process GO:0048523 283 0.014
Yeast
transcription from rna polymerase ii promoter GO:0006366 80 0.014
Yeast
cell cycle GO:0007049 93 0.014
angiogenesis GO:0001525 158 0.014
positive regulation of cellular process GO:0048522 201 0.014
Yeast
regulation of gtp catabolic process GO:0033124 2 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
Yeast
regulation of protein targeting GO:1903533 2 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
Yeast
mrna 3 end processing GO:0031124 2 0.014
cellular component assembly GO:0022607 170 0.014
regulation of binding GO:0051098 3 0.014
membrane fusion GO:0061025 2 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
actin filament polymerization GO:0030041 2 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
cellular response to radiation GO:0071478 4 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
neurological system process GO:0050877 62 0.013
regulation of rna metabolic process GO:0051252 224 0.013
Yeast
regulation of protein polymerization GO:0032271 2 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
regulation of protein metabolic process GO:0051246 56 0.013
adherens junction organization GO:0034332 4 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
organic substance biosynthetic process GO:1901576 289 0.013
Yeast
hormone transport GO:0009914 2 0.013
carbohydrate homeostasis GO:0033500 1 0.013
adult behavior GO:0030534 2 0.013
mrna metabolic process GO:0016071 20 0.013
lipid storage GO:0019915 1 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
peptidyl lysine dimethylation GO:0018027 1 0.013
nucleic acid transport GO:0050657 2 0.013
cell migration GO:0016477 237 0.013
regulation of synapse organization GO:0050807 3 0.013
cellular protein modification process GO:0006464 100 0.013
Yeast
cytoskeleton organization GO:0007010 96 0.013
rna localization GO:0006403 4 0.012
cell cycle process GO:0022402 53 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
primary neural tube formation GO:0014020 1 0.012
centrosome organization GO:0051297 1 0.012
determination of left right symmetry GO:0007368 179 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
organism emergence from protective structure GO:0071684 4 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
nucleobase containing compound transport GO:0015931 2 0.012
protein complex disassembly GO:0043241 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
response to glucose GO:0009749 3 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
peptidyl lysine methylation GO:0018022 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
rna processing GO:0006396 25 0.012
regulation of protein transport GO:0051223 3 0.012
negative regulation of mitosis GO:0045839 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
Yeast
organic cyclic compound biosynthetic process GO:1901362 223 0.012
Yeast
regulation of cellular biosynthetic process GO:0031326 245 0.012
Yeast
regulation of synapse assembly GO:0051963 3 0.012
negative regulation of gene expression GO:0010629 65 0.012
Yeast
cellular component disassembly GO:0022411 1 0.012
lipid catabolic process GO:0016042 4 0.012
positive regulation of chromatin modification GO:1903310 1 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
response to nutrient GO:0007584 3 0.011
protein metabolic process GO:0019538 183 0.011
Yeast
phosphorus metabolic process GO:0006793 109 0.011
hormone secretion GO:0046879 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
Yeast
ion transport GO:0006811 114 0.011
single organism membrane fusion GO:0044801 2 0.011
rna 3 end processing GO:0031123 2 0.011
positive regulation of secretion GO:0051047 1 0.011
negative regulation of histone modification GO:0031057 1 0.011
single organism reproductive process GO:0044702 40 0.011
protein localization to nucleus GO:0034504 3 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
retina development in camera type eye GO:0060041 146 0.011
hatching GO:0035188 4 0.010
cell cycle arrest GO:0007050 1 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
Yeast
positive regulation of carbohydrate metabolic process GO:0045913 1 0.010
protein complex localization GO:0031503 1 0.010
regulation of transcription dna templated GO:0006355 213 0.010
Yeast
mitochondrion organization GO:0007005 4 0.010

hdac8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.011