Danio rerio

0 known processes

zar1

zygote arrest 1

zar1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.294
oocyte maturation GO:0001556 4 0.216
regulation of metal ion transport GO:0010959 4 0.176
fertilization GO:0009566 3 0.160
regulation of biological quality GO:0065008 263 0.116
positive regulation of transport GO:0051050 2 0.107
nucleobase containing compound metabolic process GO:0006139 274 0.102
response to abiotic stimulus GO:0009628 122 0.101
maintenance of location GO:0051235 4 0.100
regulation of metabolic process GO:0019222 359 0.095
establishment of localization GO:0051234 244 0.091
heterocycle metabolic process GO:0046483 290 0.090
cell cell recognition GO:0009988 1 0.076
single organism localization GO:1902578 225 0.071
response to salt stress GO:0009651 10 0.066
response to stress GO:0006950 263 0.066
ion transport GO:0006811 114 0.065
positive regulation of cellular process GO:0048522 201 0.064
cellular macromolecule metabolic process GO:0044260 391 0.058
aging GO:0007568 2 0.056
regulation of multicellular organismal process GO:0051239 277 0.056
mitochondrion organization GO:0007005 4 0.056
metal ion transport GO:0030001 58 0.055
cell motility GO:0048870 244 0.055
positive regulation of muscle organ development GO:0048636 1 0.055
cellular nitrogen compound metabolic process GO:0034641 290 0.054
single fertilization GO:0007338 3 0.053
muscle structure development GO:0061061 196 0.053
intracellular signal transduction GO:0035556 85 0.052
microtubule polymerization GO:0046785 2 0.051
regulation of calcium ion transport GO:0051924 2 0.049
translational initiation GO:0006413 3 0.047
regulation of reproductive process GO:2000241 4 0.047
organic cyclic compound metabolic process GO:1901360 301 0.045
cellular component movement GO:0006928 335 0.045
regulation of chromosome segregation GO:0051983 1 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.043
single organism metabolic process GO:0044710 217 0.043
stem cell division GO:0017145 1 0.042
spindle assembly GO:0051225 2 0.042
epiboly GO:0090504 41 0.042
astrocyte differentiation GO:0048708 1 0.042
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
negative regulation of biological process GO:0048519 304 0.041
transmembrane transport GO:0055085 120 0.041
morphogenesis of an epithelial sheet GO:0002011 49 0.040
gtp metabolic process GO:0046039 4 0.038
signal transduction GO:0007165 455 0.038
cell migration GO:0016477 237 0.037
nucleic acid metabolic process GO:0090304 244 0.037
regulation of cytokine production GO:0001817 3 0.037
cation transport GO:0006812 81 0.037
lipid storage GO:0019915 1 0.037
organelle organization GO:0006996 227 0.036
reproduction GO:0000003 40 0.036
stem cell proliferation GO:0072089 4 0.036
multi organism process GO:0051704 134 0.035
cellular response to external stimulus GO:0071496 2 0.035
nucleic acid templated transcription GO:0097659 181 0.034
locomotion GO:0040011 313 0.034
positive regulation of biological process GO:0048518 253 0.034
gamete generation GO:0007276 33 0.034
central nervous system development GO:0007417 387 0.034
regulation of protein complex assembly GO:0043254 3 0.034
localization of cell GO:0051674 244 0.033
striated muscle cell differentiation GO:0051146 129 0.033
cellular localization GO:0051641 97 0.033
mitotic cell cycle embryonic GO:0045448 2 0.033
sexual reproduction GO:0019953 36 0.032
biosynthetic process GO:0009058 294 0.032
endodermal cell fate determination GO:0007493 2 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.031
negative regulation of reproductive process GO:2000242 3 0.031
regulation of transmembrane transport GO:0034762 18 0.030
muscle cell differentiation GO:0042692 139 0.030
meiotic cell cycle process GO:1903046 3 0.030
single organism transport GO:0044765 206 0.030
determination of ventral identity GO:0048264 21 0.030
negative regulation of signaling GO:0023057 96 0.030
regulation of multicellular organismal development GO:2000026 223 0.030
positive regulation of secretion GO:0051047 1 0.030
cellular protein catabolic process GO:0044257 4 0.029
generation of neurons GO:0048699 385 0.029
cellular protein metabolic process GO:0044267 129 0.029
leukocyte proliferation GO:0070661 1 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.029
centrosome localization GO:0051642 1 0.029
ion homeostasis GO:0050801 41 0.028
regulation of binding GO:0051098 3 0.028
growth GO:0040007 174 0.028
microtubule based process GO:0007017 60 0.028
stem cell maintenance GO:0019827 4 0.028
response to chemical GO:0042221 320 0.028
cell fate specification GO:0001708 68 0.028
positive regulation of exocytosis GO:0045921 1 0.028
cellular response to hypoxia GO:0071456 1 0.028
regulation of cellular protein metabolic process GO:0032268 52 0.027
exocytosis GO:0006887 1 0.027
digestive tract development GO:0048565 265 0.027
negative regulation of cell cycle process GO:0010948 9 0.027
lateral line system development GO:0048925 76 0.027
transport GO:0006810 220 0.027
cell fate commitment GO:0045165 99 0.026
immune system process GO:0002376 241 0.026
regulation of developmental process GO:0050793 247 0.026
regulation of cellular protein catabolic process GO:1903362 1 0.026
gene expression GO:0010467 252 0.026
programmed cell death GO:0012501 119 0.026
transcription dna templated GO:0006351 181 0.026
sensory organ development GO:0007423 393 0.025
negative regulation of mitosis GO:0045839 3 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
fin development GO:0033333 77 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
positive regulation of catabolic process GO:0009896 4 0.025
meiotic nuclear division GO:0007126 4 0.025
regulation of stem cell proliferation GO:0072091 2 0.024
regulation of response to stimulus GO:0048583 269 0.024
response to organic substance GO:0010033 153 0.024
cell proliferation GO:0008283 80 0.024
cellular response to decreased oxygen levels GO:0036294 1 0.024
regulation of gene expression GO:0010468 265 0.024
nitrogen compound metabolic process GO:0006807 319 0.023
digestive system development GO:0055123 289 0.023
neuroblast proliferation GO:0007405 2 0.023
regulation of ph GO:0006885 3 0.023
regulation of primary metabolic process GO:0080090 311 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
negative regulation of cytokine production GO:0001818 1 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
regulation of embryonic development GO:0045995 47 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
gtp catabolic process GO:0006184 2 0.022
negative regulation of cellular process GO:0048523 283 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
developmental maturation GO:0021700 34 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.021
regulation of signal transduction GO:0009966 225 0.021
rna metabolic process GO:0016070 219 0.021
macromolecule modification GO:0043412 111 0.021
organic substance biosynthetic process GO:1901576 289 0.020
lymphocyte homeostasis GO:0002260 1 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
single organism organelle organization GO:1902589 199 0.020
muscle tissue development GO:0060537 110 0.020
cardiac muscle tissue development GO:0048738 48 0.020
regulation of cell activation GO:0050865 1 0.020
positive regulation of multi organism process GO:0043902 3 0.020
apoptotic process GO:0006915 116 0.019
ear development GO:0043583 127 0.019
ovulation cycle process GO:0022602 2 0.019
response to lipid GO:0033993 60 0.019
cellular response to organic cyclic compound GO:0071407 38 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
calcium ion dependent exocytosis GO:0017156 1 0.019
meiotic chromosome segregation GO:0045132 3 0.019
heart looping GO:0001947 94 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of biosynthetic process GO:0009889 250 0.019
organelle fusion GO:0048284 3 0.019
fin morphogenesis GO:0033334 53 0.018
single organism reproductive process GO:0044702 40 0.018
germ line stem cell maintenance GO:0030718 2 0.018
positive regulation of calcium ion dependent exocytosis GO:0045956 1 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
blood vessel morphogenesis GO:0048514 216 0.018
regulation of gastrulation GO:0010470 24 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
positive regulation of cell activation GO:0050867 1 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.017
regulation of localization GO:0032879 104 0.017
regulation of calcium ion dependent exocytosis GO:0017158 1 0.017
vasculature development GO:0001944 278 0.017
regulation of molecular function GO:0065009 70 0.017
regulation of ion transport GO:0043269 22 0.017
mononuclear cell proliferation GO:0032943 1 0.017
sensory organ morphogenesis GO:0090596 200 0.017
organelle assembly GO:0070925 110 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of sodium ion transport GO:0002028 2 0.016
positive regulation of metabolic process GO:0009893 108 0.016
specification of organ identity GO:0010092 2 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
neuron development GO:0048666 262 0.016
response to nutrient GO:0007584 3 0.016
regulation of gtpase activity GO:0043087 2 0.016
leukocyte homeostasis GO:0001776 2 0.016
cytoskeleton organization GO:0007010 96 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
homeostatic process GO:0042592 142 0.016
cell morphogenesis GO:0000902 289 0.015
sodium ion transport GO:0006814 24 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
cellular response to oxygen levels GO:0071453 1 0.015
phosphorus metabolic process GO:0006793 109 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to estrogen stimulus GO:0071391 24 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
regulation of inflammatory response GO:0050727 2 0.015
multicellular organism reproduction GO:0032504 35 0.015
determination of dorsal ventral asymmetry GO:0048262 34 0.015
spindle assembly involved in mitosis GO:0090307 1 0.015
regulation of cell maturation GO:1903429 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of tube size GO:0035150 2 0.015
rna biosynthetic process GO:0032774 181 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
establishment of localization in cell GO:0051649 77 0.014
developmental growth GO:0048589 166 0.014
embryonic organ development GO:0048568 381 0.014
iron ion transmembrane transport GO:0034755 3 0.014
ovarian follicle development GO:0001541 2 0.014
rna localization GO:0006403 4 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.014
response to external stimulus GO:0009605 264 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
tissue remodeling GO:0048771 4 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of skeletal muscle fiber development GO:0048742 2 0.014
cell death GO:0008219 121 0.014
cellular response to nutrient levels GO:0031669 2 0.014
divalent inorganic cation transport GO:0072511 21 0.013
regulation of apoptotic process GO:0042981 98 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
cellular response to organic substance GO:0071310 105 0.013
germ line stem cell division GO:0042078 1 0.013
striated muscle tissue development GO:0014706 110 0.013
death GO:0016265 121 0.013
spemann organizer formation at the embryonic shield GO:0060063 2 0.013
protein modification process GO:0036211 100 0.013
epidermis development GO:0008544 48 0.013
cellular response to starvation GO:0009267 1 0.013
endothelial cell differentiation GO:0045446 20 0.013
protein metabolic process GO:0019538 183 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
negative regulation of multi organism process GO:0043901 3 0.013
inner ear development GO:0048839 126 0.013
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 1 0.012
retina development in camera type eye GO:0060041 146 0.012
negative regulation of cell cycle GO:0045786 14 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
cellular response to stress GO:0033554 62 0.012
lateral inhibition GO:0046331 1 0.012
calcium ion import GO:0070509 4 0.012
regulation of cell death GO:0010941 103 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
response to vitamin GO:0033273 3 0.012
rna stabilization GO:0043489 4 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
ion transmembrane transport GO:0034220 91 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
defense response GO:0006952 47 0.012
negative regulation of gene expression GO:0010629 65 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
somitogenesis GO:0001756 87 0.012
cellular component morphogenesis GO:0032989 336 0.012
immune system development GO:0002520 191 0.012
regulation of cell development GO:0060284 100 0.012
sister chromatid segregation GO:0000819 6 0.011
female gonad development GO:0008585 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
positive regulation of cell cycle GO:0045787 3 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of transcription involved in cell fate commitment GO:0060850 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
cell maturation GO:0048469 23 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
multi organism cellular process GO:0044764 2 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
cellular protein modification process GO:0006464 100 0.011
endodermal cell differentiation GO:0035987 19 0.011
response to uv GO:0009411 3 0.011
nuclear division GO:0000280 23 0.011
inner ear morphogenesis GO:0042472 63 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of programmed cell death GO:0043067 101 0.011
macromolecule methylation GO:0043414 19 0.011
tube morphogenesis GO:0035239 349 0.011
negative regulation of endodermal cell differentiation GO:1903225 8 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
immunoglobulin mediated immune response GO:0016064 3 0.010
microtubule cytoskeleton organization GO:0000226 33 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
lymphocyte proliferation GO:0046651 1 0.010
gastrulation GO:0007369 208 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010

zar1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
cardiovascular system disease DOID:1287 0 0.043
nervous system disease DOID:863 0 0.010