Danio rerio

47 known processes

mmp2

matrix metalloproteinase 2

(Aliases: wu:fa99h12,fk89d01,fa99h12,wu:fk89d01)

mmp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ameboidal type cell migration GO:0001667 143 0.981
embryonic organ development GO:0048568 381 0.934
blood vessel development GO:0001568 246 0.904
Mouse
outflow tract morphogenesis GO:0003151 1 0.850
hematopoietic or lymphoid organ development GO:0048534 191 0.848
cell substrate adhesion GO:0031589 4 0.807
inner ear development GO:0048839 126 0.793
retinal ganglion cell axon guidance GO:0031290 35 0.786
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.783
endodermal cell differentiation GO:0035987 19 0.748
Human
vasculature development GO:0001944 278 0.744
embryo development ending in birth or egg hatching GO:0009792 271 0.741
sensory organ development GO:0007423 393 0.732
convergent extension GO:0060026 118 0.685
localization of cell GO:0051674 244 0.672
Zebrafish
regulation of cellular component movement GO:0051270 55 0.659
cell migration involved in gastrulation GO:0042074 79 0.639
angiogenesis GO:0001525 158 0.629
fin regeneration GO:0031101 51 0.618
cell cycle GO:0007049 93 0.595
multi organism process GO:0051704 134 0.588
Zebrafish Mouse
tissue migration GO:0090130 37 0.575
digestive tract development GO:0048565 265 0.554
Human
cell cycle process GO:0022402 53 0.545
epithelial cell migration GO:0010631 25 0.541
cell motility GO:0048870 244 0.539
Zebrafish
ear development GO:0043583 127 0.533
cell morphogenesis involved in differentiation GO:0000904 195 0.525
tissue regeneration GO:0042246 74 0.515
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.514
retina development in camera type eye GO:0060041 146 0.513
embryonic organ morphogenesis GO:0048562 274 0.486
endoderm formation GO:0001706 29 0.485
Human
developmental growth GO:0048589 166 0.469
sensory organ morphogenesis GO:0090596 200 0.454
growth GO:0040007 174 0.441
regulation of synapse organization GO:0050807 3 0.440
regeneration GO:0031099 91 0.439
sprouting angiogenesis GO:0002040 53 0.438
digestive tract morphogenesis GO:0048546 231 0.411
Human
camera type eye morphogenesis GO:0048593 108 0.410
blood vessel morphogenesis GO:0048514 216 0.378
response to amino acid GO:0043200 2 0.377
Mouse
endoderm development GO:0007492 49 0.363
Human
eye development GO:0001654 277 0.363
nucleic acid metabolic process GO:0090304 244 0.358
cell fate commitment GO:0045165 99 0.356
cognition GO:0050890 1 0.350
camera type eye development GO:0043010 222 0.339
cell part morphogenesis GO:0032990 246 0.326
response to organic substance GO:0010033 153 0.325
Mouse
establishment of cell polarity GO:0030010 18 0.319
germ line stem cell division GO:0042078 1 0.315
response to chemical GO:0042221 320 0.308
ear morphogenesis GO:0042471 64 0.302
cellular aromatic compound metabolic process GO:0006725 295 0.298
anterior posterior pattern specification GO:0009952 152 0.298
regulation of canonical wnt signaling pathway GO:0060828 34 0.298
cell proliferation GO:0008283 80 0.297
neuroblast fate commitment GO:0014017 1 0.291
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.289
cellular component morphogenesis GO:0032989 336 0.289
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.288
regulation of signaling GO:0023051 235 0.283
regulation of epithelial cell proliferation GO:0050678 3 0.283
positive regulation of cell cycle GO:0045787 3 0.280
cellular component movement GO:0006928 335 0.280
epithelial tube morphogenesis GO:0060562 148 0.278
morphogenesis of an epithelium GO:0002009 333 0.277
negative regulation of cell migration GO:0030336 17 0.270
cytoskeleton organization GO:0007010 96 0.268
meiotic nuclear division GO:0007126 4 0.264
organelle organization GO:0006996 227 0.258
heart morphogenesis GO:0003007 156 0.253
positive regulation of cellular process GO:0048522 201 0.252
brain development GO:0007420 293 0.249
negative regulation of biological process GO:0048519 304 0.249
ossification GO:0001503 23 0.248
Mouse
multicellular organismal metabolic process GO:0044236 2 0.248
Mouse
cardioblast migration GO:0003260 7 0.241
positive regulation of programmed cell death GO:0043068 29 0.240
macromolecular complex subunit organization GO:0043933 74 0.239
cell migration GO:0016477 237 0.234
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.234
regulation of embryonic development GO:0045995 47 0.232
regulation of locomotion GO:0040012 55 0.232
zymogen activation GO:0031638 3 0.228
mitotic cell cycle process GO:1903047 48 0.227
morphogenesis of a branching structure GO:0001763 21 0.221
phagocytosis GO:0006909 3 0.219
somatic stem cell maintenance GO:0035019 1 0.217
regulation of anatomical structure morphogenesis GO:0022603 130 0.215
nitrogen compound metabolic process GO:0006807 319 0.214
cellular response to organic substance GO:0071310 105 0.209
Mouse
craniofacial suture morphogenesis GO:0097094 2 0.207
epithelium migration GO:0090132 25 0.207
response to corticosteroid GO:0031960 1 0.204
defense response GO:0006952 47 0.204
Zebrafish Mouse
convergent extension involved in gastrulation GO:0060027 71 0.203
regulation of rna metabolic process GO:0051252 224 0.202
morphogenesis of a branching epithelium GO:0061138 16 0.202
eye morphogenesis GO:0048592 144 0.199
positive regulation of cell death GO:0010942 29 0.198
cell adhesion GO:0007155 40 0.197
single organism transport GO:0044765 206 0.195
stem cell division GO:0017145 1 0.191
hemopoiesis GO:0030097 183 0.188
multicellular organismal macromolecule metabolic process GO:0044259 2 0.187
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.185
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.184
tissue remodeling GO:0048771 4 0.183
actin filament bundle organization GO:0061572 6 0.182
epithelial to mesenchymal transition GO:0001837 21 0.182
blood circulation GO:0008015 87 0.179
heart formation GO:0060914 13 0.178
positive regulation of signal transduction GO:0009967 56 0.177
glial cell migration GO:0008347 3 0.177
chordate embryonic development GO:0043009 271 0.176
organic cyclic compound metabolic process GO:1901360 301 0.176
endothelial cell migration GO:0043542 19 0.174
endodermal cell fate commitment GO:0001711 18 0.174
inner ear morphogenesis GO:0042472 63 0.168
gall bladder development GO:0061010 1 0.167
response to wounding GO:0009611 116 0.167
Zebrafish
cell fate specification GO:0001708 68 0.167
cytosolic calcium ion transport GO:0060401 3 0.160
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.154
establishment of localization in cell GO:0051649 77 0.154
formation of primary germ layer GO:0001704 62 0.151
Human
embryonic eye morphogenesis GO:0048048 30 0.149
axon guidance GO:0007411 86 0.148
notch signaling pathway GO:0007219 35 0.145
taxis GO:0042330 109 0.144
regulation of primary metabolic process GO:0080090 311 0.144
protein secretion GO:0009306 1 0.142
negative regulation of response to stimulus GO:0048585 104 0.142
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.142
wound healing GO:0042060 90 0.140
extrinsic apoptotic signaling pathway GO:0097191 3 0.140
dorsal ventral pattern formation GO:0009953 125 0.140
response to carbohydrate GO:0009743 3 0.139
gamete generation GO:0007276 33 0.137
germ line stem cell maintenance GO:0030718 2 0.135
protein import into nucleus GO:0006606 3 0.135
urogenital system development GO:0001655 97 0.135
microtubule cytoskeleton organization GO:0000226 33 0.134
mesoderm morphogenesis GO:0048332 51 0.133
establishment or maintenance of cell polarity GO:0007163 29 0.131
cellular macromolecule biosynthetic process GO:0034645 224 0.130
cell death GO:0008219 121 0.130
regulation of cell differentiation GO:0045595 142 0.129
response to external biotic stimulus GO:0043207 97 0.128
Zebrafish
immune system development GO:0002520 191 0.127
positive regulation of transport GO:0051050 2 0.127
plasma membrane repair GO:0001778 2 0.126
macrophage chemotaxis GO:0048246 3 0.125
Zebrafish
regulation of biological quality GO:0065008 263 0.125
stem cell development GO:0048864 82 0.124
endodermal cell fate specification GO:0001714 17 0.122
regulation of cell substrate adhesion GO:0010810 1 0.122
reproductive process GO:0022414 40 0.121
Mouse
embryonic hemopoiesis GO:0035162 53 0.121
biological adhesion GO:0022610 40 0.120
patterning of blood vessels GO:0001569 15 0.119
protein localization GO:0008104 40 0.117
negative regulation of chemotaxis GO:0050922 4 0.116
blood vessel endothelial cell migration GO:0043534 18 0.116
neural retina development GO:0003407 49 0.115
cell projection morphogenesis GO:0048858 244 0.113
regulation of protein catabolic process GO:0042176 1 0.112
positive regulation of epithelial cell migration GO:0010634 2 0.109
regulation of mitotic cell cycle GO:0007346 25 0.109
hepatocyte proliferation GO:0072574 2 0.109
regionalization GO:0003002 274 0.109
stem cell maintenance GO:0019827 4 0.108
regulation of localization GO:0032879 104 0.107
regulation of cell migration GO:0030334 40 0.106
establishment of mitotic spindle orientation GO:0000132 10 0.105
mesoderm development GO:0007498 88 0.105
cellular response to chemical stimulus GO:0070887 157 0.104
Zebrafish Mouse
single organism organelle organization GO:1902589 199 0.104
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.103
single organism localization GO:1902578 225 0.102
extracellular structure organization GO:0043062 27 0.101
positive regulation of endothelial cell migration GO:0010595 2 0.100
regulation of transcription dna templated GO:0006355 213 0.100
positive regulation of neuron death GO:1901216 1 0.099
endocardial cushion morphogenesis GO:0003203 3 0.099
regulation of programmed cell death GO:0043067 101 0.097
gastrulation GO:0007369 208 0.095
Human
aminoglycan metabolic process GO:0006022 9 0.094
establishment of protein localization to organelle GO:0072594 4 0.094
response to abiotic stimulus GO:0009628 122 0.093
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.092
regulation of axon extension GO:0030516 24 0.092
single organism reproductive process GO:0044702 40 0.092
Mouse
sexual reproduction GO:0019953 36 0.092
heterocycle metabolic process GO:0046483 290 0.089
positive regulation of leukocyte migration GO:0002687 2 0.089
positive regulation of apoptotic process GO:0043065 29 0.089
regulation of multicellular organismal development GO:2000026 223 0.088
response to oxygen levels GO:0070482 25 0.087
Mouse
septum transversum development GO:0003343 4 0.087
regulation of cell motility GO:2000145 46 0.086
heart field specification GO:0003128 1 0.086
branching morphogenesis of an epithelial tube GO:0048754 15 0.086
regulation of macromolecule biosynthetic process GO:0010556 225 0.086
intestinal absorption GO:0050892 2 0.085
optic placode formation involved in camera type eye formation GO:0046619 3 0.085
positive regulation of cell adhesion GO:0045785 1 0.085
regulation of cytoplasmic transport GO:1903649 4 0.084
microtubule based process GO:0007017 60 0.084
neurological system process GO:0050877 62 0.084
meiotic cell cycle process GO:1903046 3 0.084
negative regulation of cell motility GO:2000146 17 0.083
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.083
regulation of chemotaxis GO:0050920 18 0.083
aorta morphogenesis GO:0035909 3 0.083
regulation of cell morphogenesis GO:0022604 42 0.082
regulation of intracellular protein transport GO:0033157 3 0.082
protein metabolic process GO:0019538 183 0.081
Human Mouse
cellular localization GO:0051641 97 0.081
regulation of synapse assembly GO:0051963 3 0.080
negative regulation of mitotic cell cycle GO:0045930 11 0.079
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.078
immune system process GO:0002376 241 0.078
Zebrafish Mouse
positive regulation of neuron apoptotic process GO:0043525 1 0.078
artery development GO:0060840 22 0.078
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.077
collagen fibril organization GO:0030199 1 0.077
canonical wnt signaling pathway GO:0060070 48 0.077
single organism cell adhesion GO:0098602 29 0.076
locomotion GO:0040011 313 0.076
system process GO:0003008 185 0.075
muscle organ development GO:0007517 101 0.075
regulation of insulin like growth factor receptor signaling pathway GO:0043567 1 0.075
rna metabolic process GO:0016070 219 0.074
positive regulation of muscle cell differentiation GO:0051149 1 0.074
bone development GO:0060348 14 0.073
negative chemotaxis GO:0050919 1 0.072
cell morphogenesis GO:0000902 289 0.072
apoptotic process GO:0006915 116 0.072
nucleobase containing compound metabolic process GO:0006139 274 0.072
negative regulation of cellular process GO:0048523 283 0.072
retina morphogenesis in camera type eye GO:0060042 79 0.071
cellular response to growth factor stimulus GO:0071363 39 0.071
regulation of response to stress GO:0080134 36 0.070
Zebrafish Mouse
cellular response to stress GO:0033554 62 0.070
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.070
regulation of organ morphogenesis GO:2000027 35 0.070
response to drug GO:0042493 3 0.069
cellular response to external stimulus GO:0071496 2 0.069
synaptic growth at neuromuscular junction GO:0051124 2 0.069
cell growth GO:0016049 57 0.068
positive regulation of response to stimulus GO:0048584 80 0.068
Zebrafish Mouse
cytokinesis GO:0000910 3 0.067
regulation of axon guidance GO:1902667 8 0.067
mitotic cell cycle GO:0000278 64 0.067
regulation of catalytic activity GO:0050790 55 0.067
oogenesis GO:0048477 14 0.066
response to stress GO:0006950 263 0.066
Zebrafish Mouse
positive regulation of immune system process GO:0002684 17 0.065
Zebrafish Mouse
muscle structure development GO:0061061 196 0.064
regulation of cell death GO:0010941 103 0.064
determination of ventral identity GO:0048264 21 0.064
regulation of cell communication GO:0010646 232 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.064
cellular response to endogenous stimulus GO:0071495 68 0.064
Mouse
endodermal digestive tract morphogenesis GO:0061031 2 0.064
cell projection assembly GO:0030031 64 0.063
response to decreased oxygen levels GO:0036293 25 0.063
Mouse
female meiotic division GO:0007143 2 0.063
artery morphogenesis GO:0048844 14 0.063
specification of organ identity GO:0010092 2 0.063
endocardial cushion formation GO:0003272 2 0.063
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.062
mesodermal cell migration GO:0008078 12 0.062
regulation of cellular component organization GO:0051128 86 0.061
cartilage development GO:0051216 96 0.061
transcription dna templated GO:0006351 181 0.061
regulation of developmental process GO:0050793 247 0.060
regulation of gastrulation GO:0010470 24 0.060
regulation of axonogenesis GO:0050770 32 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.060
renal system development GO:0072001 94 0.060
myeloid cell differentiation GO:0030099 86 0.059
cell cycle g1 s phase transition GO:0044843 1 0.059
regulation of nuclear division GO:0051783 9 0.059
segment polarity determination GO:0007367 1 0.059
small gtpase mediated signal transduction GO:0007264 8 0.059
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.058
regulation of apoptotic process GO:0042981 98 0.058
embryonic camera type eye development GO:0031076 29 0.058
cellular response to dna damage stimulus GO:0006974 24 0.058
protein localization to nucleus GO:0034504 3 0.058
cell proliferation involved in heart morphogenesis GO:0061323 2 0.058
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.058
response to hexose GO:0009746 3 0.058
cellular response to nutrient levels GO:0031669 2 0.057
embryonic skeletal system morphogenesis GO:0048704 93 0.057
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.057
regulation of dendrite development GO:0050773 3 0.056
regulation of vasculature development GO:1901342 33 0.056
mesenchyme development GO:0060485 127 0.056
kidney development GO:0001822 92 0.056
embryonic heart tube development GO:0035050 133 0.055
regulation of protein localization to nucleus GO:1900180 2 0.055
positive regulation of cellular protein metabolic process GO:0032270 22 0.055
stem cell proliferation GO:0072089 4 0.055
regulation of cell shape GO:0008360 1 0.055
heterocycle biosynthetic process GO:0018130 215 0.054
skeletal muscle organ development GO:0060538 78 0.054
germ cell development GO:0007281 22 0.054
mesoderm formation GO:0001707 43 0.054
response to external stimulus GO:0009605 264 0.053
positive regulation of protein metabolic process GO:0051247 23 0.053
cell projection organization GO:0030030 284 0.053
connective tissue development GO:0061448 99 0.053
defense response to other organism GO:0098542 33 0.053
chondrocyte development GO:0002063 4 0.053
head development GO:0060322 303 0.052
Mouse
positive regulation of cell fate commitment GO:0010455 1 0.052
cardiac cell fate commitment GO:0060911 1 0.052
semicircular canal development GO:0060872 24 0.051
axis specification GO:0009798 43 0.051
response to bacterium GO:0009617 58 0.051
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.050
response to mechanical stimulus GO:0009612 24 0.050
regulation of peptidase activity GO:0052547 23 0.050
inner ear receptor cell differentiation GO:0060113 29 0.050
peptidyl serine modification GO:0018209 2 0.049
heart valve morphogenesis GO:0003179 8 0.049
spermatid development GO:0007286 2 0.049
g1 s transition of mitotic cell cycle GO:0000082 1 0.049
extracellular matrix constituent secretion GO:0070278 3 0.049
regulation of protein transport GO:0051223 3 0.049
regulation of wnt signaling pathway GO:0030111 53 0.049
transport GO:0006810 220 0.048
cell surface receptor signaling pathway GO:0007166 325 0.048
gland development GO:0048732 143 0.048
Zebrafish
negative regulation of apoptotic process GO:0043066 55 0.048
myelination GO:0042552 18 0.048
regulation of signal transduction GO:0009966 225 0.047
skeletal system morphogenesis GO:0048705 102 0.047
Mouse
wnt signaling pathway GO:0016055 80 0.047
reproduction GO:0000003 40 0.047
protein import GO:0017038 3 0.047
heart development GO:0007507 313 0.046
phagocytosis engulfment GO:0006911 1 0.046
regulation of cell cycle GO:0051726 52 0.046
aging GO:0007568 2 0.046
glomerulus vasculature development GO:0072012 2 0.045
negative regulation of gene expression GO:0010629 65 0.045
radial glial cell differentiation GO:0060019 2 0.045
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.045
circulatory system process GO:0003013 87 0.045
positive regulation of multicellular organismal process GO:0051240 52 0.044
pharyngeal muscle development GO:0043282 4 0.044
cellular response to retinoic acid GO:0071300 1 0.044
negative regulation of synapse assembly GO:0051964 2 0.044
regulation of protein targeting GO:1903533 2 0.043
female meiosis chromosome segregation GO:0016321 1 0.043
negative regulation of nuclear division GO:0051784 3 0.043
regulation of sequestering of calcium ion GO:0051282 4 0.043
inner ear receptor cell development GO:0060119 20 0.043
cell type specific apoptotic process GO:0097285 22 0.043
atrioventricular valve morphogenesis GO:0003181 6 0.043
ion transport GO:0006811 114 0.043
apoptotic signaling pathway GO:0097190 23 0.043
regulation of bmp signaling pathway GO:0030510 39 0.043
ensheathment of neurons GO:0007272 18 0.043
skeletal system development GO:0001501 181 0.043
Mouse
tube morphogenesis GO:0035239 349 0.042
Human
erk1 and erk2 cascade GO:0070371 4 0.042
response to glucocorticoid GO:0051384 1 0.042
negative regulation of axonogenesis GO:0050771 7 0.042
neuron death GO:0070997 21 0.042
cell matrix adhesion GO:0007160 4 0.041
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.041
regulation of nitrogen compound metabolic process GO:0051171 251 0.041
notochord development GO:0030903 54 0.041
photoreceptor cell fate commitment GO:0046552 1 0.041
somitogenesis GO:0001756 87 0.041
positive regulation of apoptotic signaling pathway GO:2001235 1 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.041
positive regulation of cytokine production GO:0001819 2 0.040
regulation of cellular protein catabolic process GO:1903362 1 0.040
osteoclast differentiation GO:0030316 1 0.040
protein modification process GO:0036211 100 0.040
negative regulation of cellular metabolic process GO:0031324 77 0.040
negative regulation of developmental process GO:0051093 65 0.040
nuclear import GO:0051170 3 0.040
positive regulation of biological process GO:0048518 253 0.040
Zebrafish Mouse
lateral mesoderm development GO:0048368 23 0.039
morphogenesis of an epithelial fold GO:0060571 1 0.039
morphogenesis of an epithelial sheet GO:0002011 49 0.039
mesodermal cell fate commitment GO:0001710 14 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
cell fate determination GO:0001709 7 0.038
keratinocyte differentiation GO:0030216 0 0.038
response to nitrogen compound GO:1901698 19 0.038
Mouse
nitric oxide metabolic process GO:0046209 2 0.038
heart looping GO:0001947 94 0.038
regulation of reactive oxygen species metabolic process GO:2000377 2 0.038
positive regulation of bmp signaling pathway GO:0030513 10 0.038
multicellular organismal reproductive process GO:0048609 35 0.038
response to inorganic substance GO:0010035 38 0.038
regulation of cysteine type endopeptidase activity GO:2000116 21 0.037
regulation of leukocyte migration GO:0002685 8 0.037
response to molecule of bacterial origin GO:0002237 14 0.037
positive regulation of myeloid cell differentiation GO:0045639 2 0.037
protein targeting to nucleus GO:0044744 3 0.036
regulation of proteolysis GO:0030162 24 0.036
single organismal cell cell adhesion GO:0016337 29 0.035
pronephros morphogenesis GO:0072114 14 0.035
determination of dorsal ventral asymmetry GO:0048262 34 0.035
response to other organism GO:0051707 97 0.035
Zebrafish
amine metabolic process GO:0009308 2 0.035
i kappab kinase nf kappab signaling GO:0007249 4 0.035
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.035
post anal tail morphogenesis GO:0036342 19 0.035
nerve development GO:0021675 45 0.035
negative regulation of epithelial cell proliferation GO:0050680 1 0.034
ectodermal cell fate specification GO:0001715 2 0.034
response to nutrient GO:0007584 3 0.034
glial cell proliferation GO:0014009 4 0.034
otolith morphogenesis GO:0032474 8 0.034
epidermal cell differentiation GO:0009913 36 0.034
single organism nuclear import GO:1902593 3 0.034
cellular response to nitrogen compound GO:1901699 6 0.034
Mouse
endothelial cell proliferation GO:0001935 11 0.033
positive regulation of cell communication GO:0010647 56 0.033
single organism metabolic process GO:0044710 217 0.033
Mouse
mechanoreceptor differentiation GO:0042490 37 0.033
regulation of endothelial cell proliferation GO:0001936 1 0.033
enzyme linked receptor protein signaling pathway GO:0007167 106 0.032
glomerulus development GO:0032835 27 0.032
habenula development GO:0021986 9 0.032
extracellular matrix organization GO:0030198 27 0.032
macromolecule localization GO:0033036 54 0.032
regulation of cell development GO:0060284 100 0.032
biosynthetic process GO:0009058 294 0.032
regulation of neuron projection development GO:0010975 40 0.032
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.032
response to metal ion GO:0010038 34 0.032
response to peptide GO:1901652 6 0.031
regulation of epithelial cell migration GO:0010632 5 0.031
response to glucose GO:0009749 3 0.031
skin development GO:0043588 54 0.031
response to alcohol GO:0097305 14 0.031
optic placode formation GO:0001743 4 0.031
intestinal cholesterol absorption GO:0030299 2 0.031
response to biotic stimulus GO:0009607 97 0.031
Zebrafish
pronephros development GO:0048793 69 0.030
digestive system development GO:0055123 289 0.030
Human
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.030
regulation of hormone secretion GO:0046883 2 0.030
regulation of cell cycle phase transition GO:1901987 8 0.030
negative regulation of endothelial cell migration GO:0010596 1 0.030
collagen metabolic process GO:0032963 2 0.030
Mouse
regulation of neuron differentiation GO:0045664 56 0.030
negative regulation of cellular component organization GO:0051129 16 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
positive regulation of catalytic activity GO:0043085 25 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.029
positive regulation of map kinase activity GO:0043406 3 0.029
activation of mapk activity GO:0000187 3 0.029
otic vesicle development GO:0071599 42 0.029
axon extension GO:0048675 45 0.029
developmental growth involved in morphogenesis GO:0060560 86 0.029
cellular response to estradiol stimulus GO:0071392 1 0.029
spermatid differentiation GO:0048515 2 0.029
organelle assembly GO:0070925 110 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
positive regulation of striated muscle cell differentiation GO:0051155 1 0.028
regulation of striated muscle tissue development GO:0016202 6 0.028
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.028
cell cell signaling involved in cell fate commitment GO:0045168 12 0.028
regulation of dna replication GO:0006275 3 0.028
regulation of cellular protein metabolic process GO:0032268 52 0.027
multi organism reproductive process GO:0044703 36 0.027
Mouse
regulation of biosynthetic process GO:0009889 250 0.027
cellular protein catabolic process GO:0044257 4 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
peptidyl serine phosphorylation GO:0018105 1 0.027
stem cell fate commitment GO:0048865 1 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.027
negative regulation of metabolic process GO:0009892 86 0.027
positive regulation of cell division GO:0051781 2 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.027
negative regulation of cellular component movement GO:0051271 18 0.027
response to monosaccharide GO:0034284 3 0.027

mmp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
charcot marie tooth disease type 4 DOID:0050541 0 0.027
neuromuscular disease DOID:440 0 0.027
charcot marie tooth disease DOID:10595 0 0.027