Danio rerio

0 known processes

pin4

protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)

(Aliases: MGC110008,zgc:110008)

pin4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.097
aging GO:0007568 2 0.069
multicellular organism growth GO:0035264 4 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.045
organic substance biosynthetic process GO:1901576 289 0.038
nucleocytoplasmic transport GO:0006913 4 0.038
biosynthetic process GO:0009058 294 0.038
regulation of multicellular organism growth GO:0040014 4 0.037
establishment of protein localization to organelle GO:0072594 4 0.037
nitrogen compound metabolic process GO:0006807 319 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
modification dependent protein catabolic process GO:0019941 3 0.033
protein acetylation GO:0006473 2 0.032
positive regulation of transport GO:0051050 2 0.032
meiotic nuclear division GO:0007126 4 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.031
cellular protein catabolic process GO:0044257 4 0.031
autophagy GO:0006914 4 0.031
cellular biosynthetic process GO:0044249 286 0.031
maintenance of location GO:0051235 4 0.030
nuclear transport GO:0051169 4 0.030
regulation of meiotic cell cycle GO:0051445 1 0.030
lipid storage GO:0019915 1 0.029
protein localization to nucleus GO:0034504 3 0.029
heterocycle metabolic process GO:0046483 290 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
protein import GO:0017038 3 0.029
nucleic acid metabolic process GO:0090304 244 0.029
single organism nuclear import GO:1902593 3 0.028
amine metabolic process GO:0009308 2 0.028
protein targeting to nucleus GO:0044744 3 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
regulation of establishment of protein localization GO:0070201 4 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
regulation of protein transport GO:0051223 3 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
protein import into nucleus GO:0006606 3 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
cellular response to external stimulus GO:0071496 2 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
cellular response to nutrient levels GO:0031669 2 0.026
nuclear import GO:0051170 3 0.026
regulation of protein localization to nucleus GO:1900180 2 0.026
single organism metabolic process GO:0044710 217 0.026
aromatic compound biosynthetic process GO:0019438 217 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
cellular amine metabolic process GO:0044106 2 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
mitochondrion organization GO:0007005 4 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
regulation of cytokine production GO:0001817 3 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
positive regulation of catabolic process GO:0009896 4 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
regulation of protein targeting GO:1903533 2 0.024
gene expression GO:0010467 252 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
stem cell proliferation GO:0072089 4 0.024
generation of neurons GO:0048699 385 0.024
regulation of metabolic process GO:0019222 359 0.023
organelle fusion GO:0048284 3 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
positive regulation of cell cycle GO:0045787 3 0.023
protein acylation GO:0043543 3 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
regulation of autophagy GO:0010506 3 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
cellular response to starvation GO:0009267 1 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
gtp catabolic process GO:0006184 2 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of biosynthetic process GO:0009889 250 0.022
stem cell maintenance GO:0019827 4 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of protein complex assembly GO:0043254 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of binding GO:0051098 3 0.022
signal transduction GO:0007165 455 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
positive regulation of biological process GO:0048518 253 0.021
establishment of localization GO:0051234 244 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
meiotic cell cycle process GO:1903046 3 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
regulation of mrna splicing via spliceosome GO:0048024 3 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
response to drug GO:0042493 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
regulation of metal ion transport GO:0010959 4 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
regulation of stem cell proliferation GO:0072091 2 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
transcription dna templated GO:0006351 181 0.020
cognition GO:0050890 1 0.020
rna metabolic process GO:0016070 219 0.019
membrane fusion GO:0061025 2 0.019
cellular ketone metabolic process GO:0042180 11 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
protein metabolic process GO:0019538 183 0.019
locomotion GO:0040011 313 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
organic acid metabolic process GO:0006082 31 0.019
regulation of rna metabolic process GO:0051252 224 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
negative regulation of cytoplasmic transport GO:1903650 2 0.019
cellular protein metabolic process GO:0044267 129 0.019
small molecule metabolic process GO:0044281 77 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
negative regulation of kinase activity GO:0033673 4 0.018
endosomal transport GO:0016197 2 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
rna biosynthetic process GO:0032774 181 0.018
phagocytosis GO:0006909 3 0.018
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
oxoacid metabolic process GO:0043436 31 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
regulation of gene expression GO:0010468 265 0.018
regulation of protein catabolic process GO:0042176 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
regulation of primary metabolic process GO:0080090 311 0.018
neuron differentiation GO:0030182 353 0.018
regulation of reproductive process GO:2000241 4 0.018
single organism membrane fusion GO:0044801 2 0.018
positive regulation of dna metabolic process GO:0051054 1 0.017
organic acid catabolic process GO:0016054 3 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
negative regulation of protein transport GO:0051224 3 0.017
atp catabolic process GO:0006200 4 0.017
regulation of synapse organization GO:0050807 3 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
translational initiation GO:0006413 3 0.017
response to stress GO:0006950 263 0.017
regulation of mrna processing GO:0050684 3 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of transporter activity GO:0032409 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
meiotic chromosome segregation GO:0045132 3 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
lipid catabolic process GO:0016042 4 0.017
negative regulation of biological process GO:0048519 304 0.017
peptide metabolic process GO:0006518 1 0.017
transport GO:0006810 220 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
negative regulation of intracellular transport GO:0032387 3 0.016
cytokinesis GO:0000910 3 0.016
female sex differentiation GO:0046660 4 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
cellular component movement GO:0006928 335 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
nucleic acid templated transcription GO:0097659 181 0.016
sensory organ development GO:0007423 393 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
immune system process GO:0002376 241 0.016
response to carbohydrate GO:0009743 3 0.016
cellular amide metabolic process GO:0043603 4 0.016
regulation of developmental process GO:0050793 247 0.016
compound eye development GO:0048749 2 0.016
positive regulation of cytokine production GO:0001819 2 0.016
b cell activation GO:0042113 2 0.016
regulation of cell activation GO:0050865 1 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
cellular component disassembly GO:0022411 1 0.016
secondary metabolic process GO:0019748 3 0.016
protein secretion GO:0009306 1 0.016
fertilization GO:0009566 3 0.016
membrane invagination GO:0010324 1 0.016
regulation of sodium ion transport GO:0002028 2 0.015
cell projection morphogenesis GO:0048858 244 0.015
rna localization GO:0006403 4 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
response to external stimulus GO:0009605 264 0.015
response to chemical GO:0042221 320 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of signaling GO:0023051 235 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
eye development GO:0001654 277 0.015
negative regulation of cellular process GO:0048523 283 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
tube morphogenesis GO:0035239 349 0.015
lymphocyte proliferation GO:0046651 1 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
vasculature development GO:0001944 278 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
regulation of protein binding GO:0043393 3 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
apoptotic process GO:0006915 116 0.015
neurotransmitter transport GO:0006836 2 0.015
positive regulation of immune effector process GO:0002699 3 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
cellular component assembly GO:0022607 170 0.014
primary neural tube formation GO:0014020 1 0.014
protein complex disassembly GO:0043241 1 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
leukocyte proliferation GO:0070661 1 0.014
positive regulation of translation GO:0045727 1 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
chordate embryonic development GO:0043009 271 0.014
macromolecular complex disassembly GO:0032984 1 0.014
interspecies interaction between organisms GO:0044419 4 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
chemosensory behavior GO:0007635 1 0.014
single organism localization GO:1902578 225 0.014
response to monosaccharide GO:0034284 3 0.014
centrosome organization GO:0051297 1 0.014
cell projection organization GO:0030030 284 0.014
rna transport GO:0050658 2 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of transcription dna templated GO:0006355 213 0.014
nuclear export GO:0051168 1 0.014
response to nutrient GO:0007584 3 0.014
neuroblast proliferation GO:0007405 2 0.014
organelle organization GO:0006996 227 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
protein localization to plasma membrane GO:0072659 1 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.013
phagocytosis engulfment GO:0006911 1 0.013
regionalization GO:0003002 274 0.013
macroautophagy GO:0016236 1 0.013
cell morphogenesis GO:0000902 289 0.013
cellular component morphogenesis GO:0032989 336 0.013
small molecule catabolic process GO:0044282 3 0.013
cell part morphogenesis GO:0032990 246 0.013
embryonic organ development GO:0048568 381 0.013
head development GO:0060322 303 0.013
cell substrate adhesion GO:0031589 4 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
regulation of response to stimulus GO:0048583 269 0.013
positive regulation of cell activation GO:0050867 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
peptidyl serine modification GO:0018209 2 0.013
blood vessel development GO:0001568 246 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
growth GO:0040007 174 0.013
negative regulation of cytokine production GO:0001818 1 0.013
response to glucose GO:0009749 3 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
golgi vesicle transport GO:0048193 3 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
response to uv GO:0009411 3 0.013
nucleic acid transport GO:0050657 2 0.013
female gonad development GO:0008585 4 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
regulation of cell communication GO:0010646 232 0.013
locomotor rhythm GO:0045475 3 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
adult behavior GO:0030534 2 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
double strand break repair GO:0006302 3 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
regulation of cell shape GO:0008360 1 0.013
programmed cell death GO:0012501 119 0.013
protein polyubiquitination GO:0000209 4 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
glucose homeostasis GO:0042593 1 0.012
microtubule organizing center organization GO:0031023 1 0.012
exocytosis GO:0006887 1 0.012
camera type eye development GO:0043010 222 0.012
viral process GO:0016032 1 0.012
response to hexose GO:0009746 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
neurotransmitter secretion GO:0007269 2 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
positive regulation of cellular process GO:0048522 201 0.012
adherens junction organization GO:0034332 4 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
regulation of dna replication GO:0006275 3 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
spermatid development GO:0007286 2 0.012
nucleobase containing compound transport GO:0015931 2 0.012
dna templated transcription elongation GO:0006354 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
protein homooligomerization GO:0051260 3 0.012
mononuclear cell proliferation GO:0032943 1 0.012
single organism organelle organization GO:1902589 199 0.012
central nervous system development GO:0007417 387 0.012
cytoplasm organization GO:0007028 4 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
heart development GO:0007507 313 0.012
cell migration GO:0016477 237 0.012
cell death GO:0008219 121 0.012
regulation of calcium ion transport GO:0051924 2 0.012
peptide transport GO:0015833 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
spermatid differentiation GO:0048515 2 0.012
regulation of chromosome segregation GO:0051983 1 0.012
organism emergence from protective structure GO:0071684 4 0.012
antimicrobial humoral response GO:0019730 2 0.012
regulation of synapse assembly GO:0051963 3 0.012
regulation of cell development GO:0060284 100 0.012
establishment of rna localization GO:0051236 3 0.012
tube closure GO:0060606 1 0.012
single fertilization GO:0007338 3 0.012
macromolecule modification GO:0043412 111 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
mitochondrial transport GO:0006839 2 0.011
somatic stem cell maintenance GO:0035019 1 0.011
developmental programmed cell death GO:0010623 4 0.011
cellular component biogenesis GO:0044085 178 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
alcohol biosynthetic process GO:0046165 2 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
angiogenesis GO:0001525 158 0.011
tissue remodeling GO:0048771 4 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
cell matrix adhesion GO:0007160 4 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of cell differentiation GO:0045595 142 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
neuron development GO:0048666 262 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
homeostatic process GO:0042592 142 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
lateral inhibition GO:0046331 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cellular response to radiation GO:0071478 4 0.011
single organism transport GO:0044765 206 0.011
startle response GO:0001964 4 0.011
retina development in camera type eye GO:0060041 146 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
response to abiotic stimulus GO:0009628 122 0.011
cell aging GO:0007569 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
protein heterooligomerization GO:0051291 1 0.011
hemopoiesis GO:0030097 183 0.011
response to corticosteroid GO:0031960 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
b cell mediated immunity GO:0019724 3 0.011
cellular protein modification process GO:0006464 100 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
regulation of jak stat cascade GO:0046425 3 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
protein stabilization GO:0050821 2 0.010
brain development GO:0007420 293 0.010
somite development GO:0061053 96 0.010
xenobiotic metabolic process GO:0006805 4 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
regulation of biological quality GO:0065008 263 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
regulation of dendrite development GO:0050773 3 0.010
somatic muscle development GO:0007525 4 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
intracellular mrna localization GO:0008298 1 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
monocarboxylic acid catabolic process GO:0072329 3 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
lipid oxidation GO:0034440 1 0.010
regulation of cellular component organization GO:0051128 86 0.010
localization of cell GO:0051674 244 0.010
rna modification GO:0009451 2 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
meiosis i GO:0007127 1 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
protein dephosphorylation GO:0006470 3 0.010
sequestering of calcium ion GO:0051208 3 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
positive regulation of multi organism process GO:0043902 3 0.010
vacuolar transport GO:0007034 2 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
digestive system development GO:0055123 289 0.010
sequestering of metal ion GO:0051238 3 0.010
centrosome cycle GO:0007098 1 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
cellular respiration GO:0045333 3 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010

pin4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
musculoskeletal system disease DOID:17 0 0.022
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.018
immune system disease DOID:2914 0 0.013
muscular disease DOID:0080000 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
muscle tissue disease DOID:66 0 0.012
myopathy DOID:423 0 0.011
cardiovascular system disease DOID:1287 0 0.010
heart disease DOID:114 0 0.010
cardiomyopathy DOID:0050700 0 0.010
intrinsic cardiomyopathy DOID:0060036 0 0.010