Danio rerio

0 known processes

elnb

elastin b

elnb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 333 0.512
larval development GO:0002164 2 0.508
embryonic organ development GO:0048568 381 0.436
embryonic organ morphogenesis GO:0048562 274 0.307
regulation of biological quality GO:0065008 263 0.291
inorganic ion transmembrane transport GO:0098660 57 0.208
maintenance of location GO:0051235 4 0.186
brain development GO:0007420 293 0.138
transmembrane transport GO:0055085 120 0.133
ion transmembrane transport GO:0034220 91 0.129
aromatic compound biosynthetic process GO:0019438 217 0.129
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.107
regulation of localization GO:0032879 104 0.103
locomotion GO:0040011 313 0.100
cation transmembrane transport GO:0098655 65 0.099
transport GO:0006810 220 0.095
single organism localization GO:1902578 225 0.093
regulation of metal ion transport GO:0010959 4 0.092
positive regulation of cellular process GO:0048522 201 0.088
system process GO:0003008 185 0.086
aging GO:0007568 2 0.086
detection of light stimulus involved in visual perception GO:0050908 7 0.086
chordate embryonic development GO:0043009 271 0.082
hormone transport GO:0009914 2 0.082
regulation of hormone secretion GO:0046883 2 0.082
calcium ion transmembrane transport GO:0070588 13 0.080
detection of light stimulus GO:0009583 12 0.079
inorganic cation transmembrane transport GO:0098662 50 0.070
regulation of cellular metabolic process GO:0031323 320 0.069
metal ion transport GO:0030001 58 0.068
cell cell signaling GO:0007267 52 0.067
heart development GO:0007507 313 0.067
cellular nitrogen compound metabolic process GO:0034641 290 0.066
regulation of multicellular organismal process GO:0051239 277 0.061
positive regulation of transport GO:0051050 2 0.060
embryonic heart tube morphogenesis GO:0003143 108 0.060
embryonic skeletal system development GO:0048706 97 0.059
neuron differentiation GO:0030182 353 0.057
regulation of metabolic process GO:0019222 359 0.056
rna metabolic process GO:0016070 219 0.056
determination of bilateral symmetry GO:0009855 204 0.056
detection of stimulus GO:0051606 29 0.056
heart morphogenesis GO:0003007 156 0.055
tube morphogenesis GO:0035239 349 0.054
nucleic acid templated transcription GO:0097659 181 0.053
positive regulation of biological process GO:0048518 253 0.053
hormone secretion GO:0046879 2 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
cellular response to oxygen levels GO:0071453 1 0.051
phototransduction GO:0007602 2 0.051
neuron projection development GO:0031175 180 0.050
cell migration GO:0016477 237 0.049
detection of abiotic stimulus GO:0009582 24 0.046
response to light stimulus GO:0009416 46 0.046
nucleobase containing compound metabolic process GO:0006139 274 0.046
cognition GO:0050890 1 0.046
organic cyclic compound metabolic process GO:1901360 301 0.045
phototransduction visible light GO:0007603 2 0.045
detection of visible light GO:0009584 12 0.045
single organism transport GO:0044765 206 0.044
endocrine process GO:0050886 2 0.043
signal transduction GO:0007165 455 0.042
response to stress GO:0006950 263 0.041
heterocycle biosynthetic process GO:0018130 215 0.041
regulation of tube size GO:0035150 2 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.039
vasculature development GO:0001944 278 0.039
heterocycle metabolic process GO:0046483 290 0.039
response to external stimulus GO:0009605 264 0.038
phagocytosis GO:0006909 3 0.038
myeloid cell homeostasis GO:0002262 56 0.038
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
immune system process GO:0002376 241 0.037
embryonic heart tube development GO:0035050 133 0.037
detection of external stimulus GO:0009581 24 0.036
blood vessel development GO:0001568 246 0.035
regulation of developmental process GO:0050793 247 0.035
cell morphogenesis GO:0000902 289 0.035
regulation of response to stimulus GO:0048583 269 0.035
epithelial tube morphogenesis GO:0060562 148 0.035
camera type eye development GO:0043010 222 0.035
organic substance biosynthetic process GO:1901576 289 0.035
amino acid transport GO:0006865 2 0.035
response to radiation GO:0009314 51 0.034
neuron neuron synaptic transmission GO:0007270 1 0.034
positive regulation of cell cycle GO:0045787 3 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.034
blood vessel morphogenesis GO:0048514 216 0.033
regulation of transport GO:0051049 45 0.033
regulation of calcium ion transport GO:0051924 2 0.033
sensory perception GO:0007600 39 0.032
negative regulation of biological process GO:0048519 304 0.032
stem cell proliferation GO:0072089 4 0.032
lipid storage GO:0019915 1 0.031
sensory organ development GO:0007423 393 0.031
homeostatic process GO:0042592 142 0.031
regulation of cell communication GO:0010646 232 0.031
gene expression GO:0010467 252 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.029
taxis GO:0042330 109 0.029
endocrine hormone secretion GO:0060986 2 0.028
regulation of nervous system development GO:0051960 90 0.028
response to other organism GO:0051707 97 0.028
release of sequestered calcium ion into cytosol GO:0051209 3 0.028
regulation of transcription dna templated GO:0006355 213 0.028
establishment of localization GO:0051234 244 0.028
muscle structure development GO:0061061 196 0.028
regulation of system process GO:0044057 40 0.027
regulation of blood vessel size GO:0050880 2 0.027
growth GO:0040007 174 0.027
response to chemical GO:0042221 320 0.027
regulation of primary metabolic process GO:0080090 311 0.027
cell projection morphogenesis GO:0048858 244 0.027
negative regulation of sequestering of calcium ion GO:0051283 4 0.027
cell motility GO:0048870 244 0.026
cellular component movement GO:0006928 335 0.026
regulation of gene expression GO:0010468 265 0.026
regulation of inflammatory response GO:0050727 2 0.026
regulation of neurogenesis GO:0050767 87 0.026
response to glucose GO:0009749 3 0.026
regulation of anatomical structure size GO:0090066 33 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
axon development GO:0061564 166 0.025
regulation of reproductive process GO:2000241 4 0.025
sensory perception of light stimulus GO:0050953 19 0.025
biosynthetic process GO:0009058 294 0.024
rhodopsin mediated signaling pathway GO:0016056 1 0.024
neuron projection morphogenesis GO:0048812 161 0.024
regulation of ion transport GO:0043269 22 0.024
skeletal muscle organ development GO:0060538 78 0.024
response to monosaccharide GO:0034284 3 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.023
regulation of signaling GO:0023051 235 0.023
cation transport GO:0006812 81 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
motor neuron axon guidance GO:0008045 23 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
muscle organ development GO:0007517 101 0.022
determination of left right symmetry GO:0007368 179 0.022
apoptotic process GO:0006915 116 0.022
epithelial cell development GO:0002064 42 0.022
negative regulation of defense response GO:0031348 2 0.022
cell part morphogenesis GO:0032990 246 0.022
regulation of cell shape GO:0008360 1 0.022
positive regulation of nervous system development GO:0051962 25 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
negative regulation of cellular process GO:0048523 283 0.021
muscle tissue development GO:0060537 110 0.021
adult behavior GO:0030534 2 0.021
gastrulation GO:0007369 208 0.021
light induced release of internally sequestered calcium ion GO:0008377 1 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.020
glucose homeostasis GO:0042593 1 0.020
transcription dna templated GO:0006351 181 0.020
carbohydrate biosynthetic process GO:0016051 1 0.020
chemotaxis GO:0006935 104 0.020
response to carbohydrate GO:0009743 3 0.020
response to hexose GO:0009746 3 0.020
embryonic skeletal system morphogenesis GO:0048704 93 0.019
peptide transport GO:0015833 1 0.019
skeletal system morphogenesis GO:0048705 102 0.019
regulation of blood pressure GO:0008217 1 0.019
specification of symmetry GO:0009799 204 0.019
mesenchyme development GO:0060485 127 0.019
regulation of cell development GO:0060284 100 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
nucleic acid metabolic process GO:0090304 244 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.018
regulation of cell differentiation GO:0045595 142 0.018
developmental growth GO:0048589 166 0.018
heart looping GO:0001947 94 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
regulation of protein catabolic process GO:0042176 1 0.017
chemosensory behavior GO:0007635 1 0.017
multicellular organism growth GO:0035264 4 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
response to vitamin GO:0033273 3 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
response to oxygen levels GO:0070482 25 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
g protein coupled receptor signaling pathway GO:0007186 74 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
regulation of dendrite development GO:0050773 3 0.016
skeletal system development GO:0001501 181 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
single organism membrane fusion GO:0044801 2 0.016
lipid catabolic process GO:0016042 4 0.016
response to bacterium GO:0009617 58 0.016
stem cell maintenance GO:0019827 4 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.016
cellular response to decreased oxygen levels GO:0036294 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
stem cell fate commitment GO:0048865 1 0.016
regulation of hormone levels GO:0010817 21 0.016
digestive system development GO:0055123 289 0.016
intracellular signal transduction GO:0035556 85 0.015
regulation of rna metabolic process GO:0051252 224 0.015
rna biosynthetic process GO:0032774 181 0.015
nuclear transport GO:0051169 4 0.015
regulation of transmembrane transport GO:0034762 18 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
negative regulation of secretion by cell GO:1903531 2 0.015
regulation of membrane potential GO:0042391 23 0.015
positive regulation of secretion GO:0051047 1 0.015
synaptic vesicle transport GO:0048489 1 0.015
axonogenesis GO:0007409 152 0.015
death GO:0016265 121 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
neuroblast proliferation GO:0007405 2 0.014
interspecies interaction between organisms GO:0044419 4 0.014
sensory perception of mechanical stimulus GO:0050954 16 0.014
carbohydrate homeostasis GO:0033500 1 0.014
exocytosis GO:0006887 1 0.014
regulation of dna replication GO:0006275 3 0.014
response to metal ion GO:0010038 34 0.014
epithelial cell differentiation GO:0030855 116 0.014
gtp metabolic process GO:0046039 4 0.014
protein metabolic process GO:0019538 183 0.014
cellular biosynthetic process GO:0044249 286 0.014
calcium mediated signaling GO:0019722 2 0.014
digestive tract morphogenesis GO:0048546 231 0.014
behavior GO:0007610 74 0.014
detection of light stimulus involved in sensory perception GO:0050962 7 0.014
sequestering of calcium ion GO:0051208 3 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
cell death GO:0008219 121 0.013
defense response to bacterium GO:0042742 22 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
regulation of behavior GO:0050795 24 0.013
single organism metabolic process GO:0044710 217 0.013
defense response GO:0006952 47 0.013
neuromuscular process controlling balance GO:0050885 3 0.013
calcium ion import GO:0070509 4 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
synaptic vesicle localization GO:0097479 1 0.013
regulation of signal transduction GO:0009966 225 0.013
cell substrate adhesion GO:0031589 4 0.013
notochord development GO:0030903 54 0.013
response to decreased oxygen levels GO:0036293 25 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
regulation of biosynthetic process GO:0009889 250 0.013
renal system development GO:0072001 94 0.013
cellular response to light stimulus GO:0071482 4 0.013
cellular localization GO:0051641 97 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
defense response to other organism GO:0098542 33 0.013
cell cycle GO:0007049 93 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
visual perception GO:0007601 17 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
cellular response to reactive oxygen species GO:0034614 2 0.012
regulation of cell cycle GO:0051726 52 0.012
ion transport GO:0006811 114 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
embryonic skeletal joint development GO:0072498 3 0.012
meiotic nuclear division GO:0007126 4 0.012
negative regulation of dna replication GO:0008156 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of cytokine production GO:0001817 3 0.012
regulation of apoptotic process GO:0042981 98 0.012
monocarboxylic acid catabolic process GO:0072329 3 0.012
multicellular organismal response to stress GO:0033555 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
protein homooligomerization GO:0051260 3 0.012
swim bladder development GO:0048794 19 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
organelle fusion GO:0048284 3 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.011
eye development GO:0001654 277 0.011
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.011
establishment of localization in cell GO:0051649 77 0.011
tube closure GO:0060606 1 0.011
regulation of cell activation GO:0050865 1 0.011
cell projection organization GO:0030030 284 0.011
regulation of jak stat cascade GO:0046425 3 0.011
regulation of neuron projection development GO:0010975 40 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
l amino acid transport GO:0015807 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
defense response to gram negative bacterium GO:0050829 8 0.011
response to external biotic stimulus GO:0043207 97 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cellular protein catabolic process GO:0044257 4 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
fatty acid catabolic process GO:0009062 1 0.011
regulation of cell growth GO:0001558 29 0.011
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.011
cellular component biogenesis GO:0044085 178 0.011
type b pancreatic cell development GO:0003323 4 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
ameboidal type cell migration GO:0001667 143 0.011
cellular response to radiation GO:0071478 4 0.011
meiotic cell cycle process GO:1903046 3 0.011
negative regulation of signaling GO:0023057 96 0.011
positive regulation of cell activation GO:0050867 1 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
positive regulation of catabolic process GO:0009896 4 0.011
cell aging GO:0007569 2 0.011
localization of cell GO:0051674 244 0.011
ribose phosphate biosynthetic process GO:0046390 20 0.011
neurotransmitter transport GO:0006836 2 0.011
regulation of transporter activity GO:0032409 2 0.011
protein secretion GO:0009306 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
erythrocyte differentiation GO:0030218 54 0.010
regulation of lipid transport GO:0032368 4 0.010
regulation of programmed cell death GO:0043067 101 0.010
myotube differentiation GO:0014902 45 0.010
outflow tract morphogenesis GO:0003151 1 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
purine nucleotide biosynthetic process GO:0006164 20 0.010
neuroblast differentiation GO:0014016 1 0.010
positive regulation of cell division GO:0051781 2 0.010
multicellular organismal macromolecule metabolic process GO:0044259 2 0.010
positive regulation of lipase activity GO:0060193 1 0.010
muscle fiber development GO:0048747 52 0.010

elnb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
musculoskeletal system disease DOID:17 0 0.029
disease of metabolism DOID:0014667 0 0.020
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.015
nervous system disease DOID:863 0 0.013
cardiovascular system disease DOID:1287 0 0.011