Danio rerio

0 known processes

zgc:113625

zgc:113625

zgc:113625 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of ion transmembrane transporter activity GO:0032412 2 0.136
regulation of muscle contraction GO:0006937 3 0.130
atp catabolic process GO:0006200 4 0.093
regulation of purine nucleotide catabolic process GO:0033121 2 0.087
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.085
ribonucleoside monophosphate catabolic process GO:0009158 4 0.085
establishment of protein localization to plasma membrane GO:0090002 1 0.080
regulation of nucleotide catabolic process GO:0030811 2 0.080
nucleoside monophosphate catabolic process GO:0009125 4 0.078
regulation of nucleoside metabolic process GO:0009118 2 0.073
protein polymerization GO:0051258 4 0.071
regulation of binding GO:0051098 3 0.069
purine nucleoside monophosphate catabolic process GO:0009128 4 0.068
cytokinesis GO:0000910 3 0.064
regulation of metal ion transport GO:0010959 4 0.064
actomyosin structure organization GO:0031032 53 0.063
heart process GO:0003015 71 0.062
striated muscle tissue development GO:0014706 110 0.061
muscle tissue development GO:0060537 110 0.059
cardiac muscle cell development GO:0055013 20 0.056
maintenance of location GO:0051235 4 0.055
regulation of biological quality GO:0065008 263 0.053
larval development GO:0002164 2 0.053
actin polymerization or depolymerization GO:0008154 2 0.052
positive regulation of transport GO:0051050 2 0.051
regulation of cell projection assembly GO:0060491 4 0.050
muscle cell development GO:0055001 115 0.049
cellular component disassembly GO:0022411 1 0.047
regulation of metabolic process GO:0019222 359 0.047
aging GO:0007568 2 0.046
regulation of protein polymerization GO:0032271 2 0.046
lamellipodium assembly GO:0030032 1 0.044
system process GO:0003008 185 0.044
regulation of blood circulation GO:1903522 32 0.044
muscle structure development GO:0061061 196 0.044
circulatory system process GO:0003013 87 0.044
sequestering of metal ion GO:0051238 3 0.043
heart development GO:0007507 313 0.043
regulation of protein complex assembly GO:0043254 3 0.043
cellular component assembly involved in morphogenesis GO:0010927 107 0.042
cardiac myofibril assembly GO:0055003 9 0.042
blood circulation GO:0008015 87 0.042
cardiac atrium morphogenesis GO:0003209 2 0.042
ventricular cardiac muscle tissue development GO:0003229 3 0.041
cellular component morphogenesis GO:0032989 336 0.041
negative regulation of biological process GO:0048519 304 0.041
rna localization GO:0006403 4 0.040
regulation of protein binding GO:0043393 3 0.039
regulation of neural precursor cell proliferation GO:2000177 3 0.038
regulation of transporter activity GO:0032409 2 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
cardiac atrium development GO:0003230 4 0.038
macromolecular complex disassembly GO:0032984 1 0.037
regulation of protein depolymerization GO:1901879 1 0.036
negative regulation of cellular process GO:0048523 283 0.036
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.036
fertilization GO:0009566 3 0.035
regulation of blood pressure GO:0008217 1 0.035
small molecule metabolic process GO:0044281 77 0.034
cellular component assembly GO:0022607 170 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.034
protein localization to plasma membrane GO:0072659 1 0.034
inorganic cation transmembrane transport GO:0098662 50 0.032
protein stabilization GO:0050821 2 0.032
cellular component biogenesis GO:0044085 178 0.032
regulation of developmental process GO:0050793 247 0.032
muscle cell differentiation GO:0042692 139 0.032
cardiac muscle tissue development GO:0048738 48 0.032
regulation of striated muscle contraction GO:0006942 2 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.031
cardiac muscle cell differentiation GO:0055007 30 0.031
cognition GO:0050890 1 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
cell cycle g1 s phase transition GO:0044843 1 0.031
intracellular mrna localization GO:0008298 1 0.031
actin filament polymerization GO:0030041 2 0.031
striated muscle cell development GO:0055002 108 0.030
regulation of cell shape GO:0008360 1 0.030
regulation of circadian rhythm GO:0042752 4 0.030
heart contraction GO:0060047 71 0.030
somatic muscle development GO:0007525 4 0.030
protein targeting to nucleus GO:0044744 3 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.029
cell projection organization GO:0030030 284 0.029
striated muscle contraction GO:0006941 12 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
protein complex disassembly GO:0043241 1 0.028
gene expression GO:0010467 252 0.028
regulation of transmembrane transporter activity GO:0022898 2 0.027
single organism metabolic process GO:0044710 217 0.027
myofibril assembly GO:0030239 48 0.027
circadian sleep wake cycle sleep GO:0050802 1 0.026
regulation of system process GO:0044057 40 0.026
organelle assembly GO:0070925 110 0.026
lipid storage GO:0019915 1 0.026
calcium ion transport into cytosol GO:0060402 3 0.026
generation of neurons GO:0048699 385 0.026
single organism organelle organization GO:1902589 199 0.025
organic acid metabolic process GO:0006082 31 0.025
spermatid development GO:0007286 2 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
striated muscle cell differentiation GO:0051146 129 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
oocyte anterior posterior axis specification GO:0007314 4 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
small molecule catabolic process GO:0044282 3 0.025
gtp catabolic process GO:0006184 2 0.025
protein import into nucleus GO:0006606 3 0.024
heart morphogenesis GO:0003007 156 0.024
sequestering of calcium ion GO:0051208 3 0.024
cardiac cell development GO:0055006 21 0.024
regionalization GO:0003002 274 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
response to glucocorticoid GO:0051384 1 0.023
regulation of sequestering of calcium ion GO:0051282 4 0.023
locomotion GO:0040011 313 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
regulation of molecular function GO:0065009 70 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
eye development GO:0001654 277 0.022
cytoplasm organization GO:0007028 4 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
heterocycle metabolic process GO:0046483 290 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
multicellular organism growth GO:0035264 4 0.022
meiotic nuclear division GO:0007126 4 0.022
actin filament based movement GO:0030048 1 0.022
regulation of membrane potential GO:0042391 23 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
sleep GO:0030431 1 0.021
regulation of neurotransmitter secretion GO:0046928 1 0.021
inositol lipid mediated signaling GO:0048017 2 0.021
cellular response to starvation GO:0009267 1 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
muscle system process GO:0003012 20 0.021
regulation of dendrite development GO:0050773 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
protein import GO:0017038 3 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
neurotransmitter secretion GO:0007269 2 0.021
amine metabolic process GO:0009308 2 0.021
cellular response to nutrient levels GO:0031669 2 0.021
regulation of calcium ion transport GO:0051924 2 0.020
phagocytosis engulfment GO:0006911 1 0.020
regulation of cytokine production GO:0001817 3 0.020
chemosensory behavior GO:0007635 1 0.020
nuclear transport GO:0051169 4 0.020
cellular component movement GO:0006928 335 0.020
single organism nuclear import GO:1902593 3 0.020
response to corticosteroid GO:0031960 1 0.020
regulation of cellular component organization GO:0051128 86 0.020
spermatid differentiation GO:0048515 2 0.020
protein localization to nucleus GO:0034504 3 0.020
regulation of protein complex disassembly GO:0043244 1 0.020
establishment of localization GO:0051234 244 0.020
lipid homeostasis GO:0055088 3 0.020
cytoskeleton dependent cytokinesis GO:0061640 3 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
myotube differentiation GO:0014902 45 0.020
cell part morphogenesis GO:0032990 246 0.020
regulation of cardiac muscle contraction GO:0055117 2 0.020
oxoacid metabolic process GO:0043436 31 0.020
cell morphogenesis GO:0000902 289 0.019
post embryonic morphogenesis GO:0009886 4 0.019
stem cell proliferation GO:0072089 4 0.019
skeletal muscle tissue development GO:0007519 67 0.019
phagocytosis GO:0006909 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
lamellipodium organization GO:0097581 1 0.019
dna templated transcription elongation GO:0006354 3 0.019
nuclear import GO:0051170 3 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
anterior posterior pattern specification GO:0009952 152 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.019
mitochondrion organization GO:0007005 4 0.019
locomotor rhythm GO:0045475 3 0.019
membrane fusion GO:0061025 2 0.019
b cell activation GO:0042113 2 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
regulation of gene expression GO:0010468 265 0.018
somitogenesis GO:0001756 87 0.018
regulation of heart contraction GO:0008016 32 0.018
actin mediated cell contraction GO:0070252 1 0.018
sarcomere organization GO:0045214 26 0.018
neuron differentiation GO:0030182 353 0.018
actin filament based process GO:0030029 64 0.018
response to drug GO:0042493 3 0.018
cellular response to external stimulus GO:0071496 2 0.018
positive regulation of catabolic process GO:0009896 4 0.018
adult behavior GO:0030534 2 0.018
regulation of neurotransmitter transport GO:0051588 1 0.018
sensory organ development GO:0007423 393 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
homeostatic process GO:0042592 142 0.017
cellular ketone metabolic process GO:0042180 11 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
organelle organization GO:0006996 227 0.017
response to organic substance GO:0010033 153 0.017
gtp metabolic process GO:0046039 4 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
cytoskeleton organization GO:0007010 96 0.017
regulation of cell morphogenesis GO:0022604 42 0.017
response to stress GO:0006950 263 0.017
regulation of synapse organization GO:0050807 3 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
response to external stimulus GO:0009605 264 0.017
pole plasm assembly GO:0007315 4 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
single fertilization GO:0007338 3 0.016
regulation of reproductive process GO:2000241 4 0.016
regulation of synapse assembly GO:0051963 3 0.016
regulation of rho protein signal transduction GO:0035023 2 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
calcium mediated signaling GO:0019722 2 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.016
response to chemical GO:0042221 320 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
cation transmembrane transport GO:0098655 65 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
regulation of gtpase activity GO:0043087 2 0.016
organic substance biosynthetic process GO:1901576 289 0.016
cellular amine metabolic process GO:0044106 2 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
signal transduction GO:0007165 455 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
stem cell maintenance GO:0019827 4 0.016
segmentation GO:0035282 97 0.016
positive regulation of cell adhesion GO:0045785 1 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
multi organism process GO:0051704 134 0.015
regulation of primary metabolic process GO:0080090 311 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
smooth muscle contraction GO:0006939 2 0.015
cardiac muscle cell contraction GO:0086003 1 0.015
localization of cell GO:0051674 244 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
actin cytoskeleton organization GO:0030036 63 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
interspecies interaction between organisms GO:0044419 4 0.015
cardiac muscle contraction GO:0060048 6 0.015
regulation of organ growth GO:0046620 3 0.015
regulation of response to biotic stimulus GO:0002831 2 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
digestive tract development GO:0048565 265 0.014
transport GO:0006810 220 0.014
metal ion transport GO:0030001 58 0.014
release of sequestered calcium ion into cytosol GO:0051209 3 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
intestinal absorption GO:0050892 2 0.014
embryonic organ development GO:0048568 381 0.014
regulation of protein transport GO:0051223 3 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
circadian sleep wake cycle process GO:0022410 2 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
neuroblast proliferation GO:0007405 2 0.014
response to hormone GO:0009725 48 0.014
somite development GO:0061053 96 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
single organism localization GO:1902578 225 0.014
cardiac muscle fiber development GO:0048739 3 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
cytokinetic process GO:0032506 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
membrane invagination GO:0010324 1 0.013
transmembrane transport GO:0055085 120 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
lipid catabolic process GO:0016042 4 0.013
organophosphate metabolic process GO:0019637 37 0.013
cell cycle GO:0007049 93 0.013
neuron development GO:0048666 262 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
single organism transport GO:0044765 206 0.013
protein metabolic process GO:0019538 183 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
regulation of organelle assembly GO:1902115 4 0.012
neurotransmitter transport GO:0006836 2 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
circadian sleep wake cycle GO:0042745 2 0.012
growth GO:0040007 174 0.012
cellular protein complex disassembly GO:0043624 1 0.012
regulation of filopodium assembly GO:0051489 2 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
action potential GO:0001508 19 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
regulation of hydrolase activity GO:0051336 28 0.012
regulation of blood vessel size GO:0050880 2 0.012
synaptic vesicle localization GO:0097479 1 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
regulation of actin filament based movement GO:1903115 1 0.012
directional locomotion GO:0033058 1 0.012
vasculature development GO:0001944 278 0.012
regulation of response to stimulus GO:0048583 269 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
muscle contraction GO:0006936 18 0.012
nucleic acid metabolic process GO:0090304 244 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of heart rate GO:0002027 5 0.012
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
synaptic vesicle transport GO:0048489 1 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of cell development GO:0060284 100 0.011
apical junction assembly GO:0043297 1 0.011
cell substrate adhesion GO:0031589 4 0.011
ion homeostasis GO:0050801 41 0.011
cardiac chamber development GO:0003205 19 0.011
negative regulation of blood circulation GO:1903523 2 0.011
purine containing compound metabolic process GO:0072521 29 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
aromatic compound catabolic process GO:0019439 15 0.011
secondary metabolic process GO:0019748 3 0.011
startle response GO:0001964 4 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cell cycle arrest GO:0007050 1 0.011
membrane repolarization GO:0086009 2 0.011
biosynthetic process GO:0009058 294 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
protein depolymerization GO:0051261 1 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
positive regulation of immune effector process GO:0002699 3 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010
leukocyte proliferation GO:0070661 1 0.010
tissue remodeling GO:0048771 4 0.010
behavior GO:0007610 74 0.010
inorganic ion transmembrane transport GO:0098660 57 0.010
protein homooligomerization GO:0051260 3 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
multi organism cellular process GO:0044764 2 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
heart looping GO:0001947 94 0.010
regulation of localization GO:0032879 104 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
cardiocyte differentiation GO:0035051 44 0.010
single organism membrane fusion GO:0044801 2 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
cellular biosynthetic process GO:0044249 286 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
mechanosensory behavior GO:0007638 2 0.010
long chain fatty acid metabolic process GO:0001676 1 0.010
cell motility GO:0048870 244 0.010

zgc:113625 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.144
musculoskeletal system disease DOID:17 0 0.144
muscular disease DOID:0080000 0 0.078
myopathy DOID:423 0 0.075
muscle tissue disease DOID:66 0 0.075
cardiovascular system disease DOID:1287 0 0.035
heart disease DOID:114 0 0.033
cardiomyopathy DOID:0050700 0 0.033
distal arthrogryposis DOID:0050646 0 0.022
intrinsic cardiomyopathy DOID:0060036 0 0.018
hypertrophic cardiomyopathy DOID:11984 0 0.016
nervous system disease DOID:863 0 0.010