Danio rerio

0 known processes

tfam

transcription factor A, mitochondrial

(Aliases: MGC153358,zgc:153358)

tfam biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic dna integrity checkpoint GO:0044774 4 0.393
mitotic g2 dna damage checkpoint GO:0007095 3 0.352
mitotic dna damage checkpoint GO:0044773 4 0.271
mitotic g2 m transition checkpoint GO:0044818 3 0.195
organic cyclic compound biosynthetic process GO:1901362 223 0.191
g2 dna damage checkpoint GO:0031572 3 0.183
organic cyclic compound metabolic process GO:1901360 301 0.178
cellular macromolecule metabolic process GO:0044260 391 0.165
larval development GO:0002164 2 0.160
cellular nitrogen compound biosynthetic process GO:0044271 218 0.136
cytoskeleton organization GO:0007010 96 0.131
aromatic compound biosynthetic process GO:0019438 217 0.127
nucleoside monophosphate catabolic process GO:0009125 4 0.122
negative regulation of cellular process GO:0048523 283 0.120
purine nucleoside monophosphate catabolic process GO:0009128 4 0.120
nucleic acid metabolic process GO:0090304 244 0.107
nucleobase containing compound biosynthetic process GO:0034654 205 0.101
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.096
heterocycle biosynthetic process GO:0018130 215 0.089
cellular aromatic compound metabolic process GO:0006725 295 0.089
cellular nitrogen compound metabolic process GO:0034641 290 0.088
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.085
regulation of macromolecule metabolic process GO:0060255 317 0.084
organic substance biosynthetic process GO:1901576 289 0.081
negative regulation of metabolic process GO:0009892 86 0.081
biosynthetic process GO:0009058 294 0.081
cellular biosynthetic process GO:0044249 286 0.079
transcription dna templated GO:0006351 181 0.078
modification dependent protein catabolic process GO:0019941 3 0.078
negative regulation of biological process GO:0048519 304 0.074
ribonucleoside monophosphate catabolic process GO:0009158 4 0.071
regulation of macromolecule biosynthetic process GO:0010556 225 0.070
nitrogen compound metabolic process GO:0006807 319 0.070
digestive tract development GO:0048565 265 0.067
regulation of nitrogen compound metabolic process GO:0051171 251 0.066
cell surface receptor signaling pathway GO:0007166 325 0.066
regulation of nucleic acid templated transcription GO:1903506 213 0.065
negative regulation of macromolecule metabolic process GO:0010605 76 0.064
regulation of rna biosynthetic process GO:2001141 213 0.063
single organism nuclear import GO:1902593 3 0.062
regulation of cellular metabolic process GO:0031323 320 0.061
meiotic chromosome segregation GO:0045132 3 0.059
regulation of primary metabolic process GO:0080090 311 0.059
regulation of transcription dna templated GO:0006355 213 0.055
rna biosynthetic process GO:0032774 181 0.055
regulation of metabolic process GO:0019222 359 0.054
protein localization to nucleus GO:0034504 3 0.053
nuclear transport GO:0051169 4 0.052
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.051
response to stress GO:0006950 263 0.050
immune system process GO:0002376 241 0.050
regulation of reproductive process GO:2000241 4 0.050
lateral inhibition GO:0046331 1 0.048
nucleic acid templated transcription GO:0097659 181 0.048
cellular component assembly involved in morphogenesis GO:0010927 107 0.047
meiotic cell cycle process GO:1903046 3 0.047
modification dependent macromolecule catabolic process GO:0043632 3 0.047
protein targeting to nucleus GO:0044744 3 0.046
rna metabolic process GO:0016070 219 0.046
protein import into nucleus GO:0006606 3 0.045
negative regulation of protein kinase activity GO:0006469 4 0.044
protein complex localization GO:0031503 1 0.043
lipid storage GO:0019915 1 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.042
cell cycle g1 s phase transition GO:0044843 1 0.041
head development GO:0060322 303 0.041
organelle organization GO:0006996 227 0.040
cellular response to dna damage stimulus GO:0006974 24 0.040
single organism organelle organization GO:1902589 199 0.039
sensory organ development GO:0007423 393 0.038
mitotic cell cycle checkpoint GO:0007093 5 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.037
regulation of cell projection assembly GO:0060491 4 0.037
regulation of gene expression GO:0010468 265 0.036
determination of bilateral symmetry GO:0009855 204 0.036
establishment of protein localization to organelle GO:0072594 4 0.035
regulation of binding GO:0051098 3 0.035
regulation of biological quality GO:0065008 263 0.035
gene expression GO:0010467 252 0.035
g1 s transition of mitotic cell cycle GO:0000082 1 0.035
adult behavior GO:0030534 2 0.034
negative regulation of gene expression GO:0010629 65 0.034
regulation of biosynthetic process GO:0009889 250 0.034
actin filament based process GO:0030029 64 0.033
regulation of nuclease activity GO:0032069 1 0.033
actin cytoskeleton organization GO:0030036 63 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
organonitrogen compound metabolic process GO:1901564 74 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
cytokinesis GO:0000910 3 0.031
regionalization GO:0003002 274 0.031
central nervous system development GO:0007417 387 0.030
actomyosin structure organization GO:0031032 53 0.030
nuclear import GO:0051170 3 0.030
amine metabolic process GO:0009308 2 0.030
negative regulation of catabolic process GO:0009895 3 0.030
negative regulation of kinase activity GO:0033673 4 0.029
regulation of endothelial cell proliferation GO:0001936 1 0.029
cellular macromolecular complex assembly GO:0034622 24 0.029
macromolecule biosynthetic process GO:0009059 227 0.029
negative regulation of cell cycle phase transition GO:1901988 5 0.028
signal transduction GO:0007165 455 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.027
heterocycle metabolic process GO:0046483 290 0.027
protein modification by small protein removal GO:0070646 1 0.027
single organism transport GO:0044765 206 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
peptidyl lysine acetylation GO:0018394 2 0.027
myotube cell development GO:0014904 35 0.026
chromosome organization involved in meiosis GO:0070192 1 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of filopodium assembly GO:0051489 2 0.026
i kappab kinase nf kappab signaling GO:0007249 4 0.026
single organism metabolic process GO:0044710 217 0.026
cellular response to stress GO:0033554 62 0.025
programmed cell death GO:0012501 119 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.025
death GO:0016265 121 0.025
protein metabolic process GO:0019538 183 0.025
response to biotic stimulus GO:0009607 97 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
protein stabilization GO:0050821 2 0.024
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.023
negative regulation of cellular catabolic process GO:0031330 3 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
muscle cell differentiation GO:0042692 139 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
myofibril assembly GO:0030239 48 0.023
mitochondrion organization GO:0007005 4 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
dna integrity checkpoint GO:0031570 6 0.022
cellular protein catabolic process GO:0044257 4 0.022
meiotic nuclear division GO:0007126 4 0.021
protein acylation GO:0043543 3 0.021
maintenance of location GO:0051235 4 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.021
regulation of receptor activity GO:0010469 2 0.021
oxoacid metabolic process GO:0043436 31 0.021
inorganic ion transmembrane transport GO:0098660 57 0.021
cell migration GO:0016477 237 0.020
regulation of rna metabolic process GO:0051252 224 0.020
cell death GO:0008219 121 0.020
chordate embryonic development GO:0043009 271 0.020
muscle cell development GO:0055001 115 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
digestive system development GO:0055123 289 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
inner ear receptor cell fate commitment GO:0060120 4 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
muscle tissue development GO:0060537 110 0.019
cellular component assembly GO:0022607 170 0.018
response to nitrogen compound GO:1901698 19 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
muscle structure development GO:0061061 196 0.018
negative regulation of rna metabolic process GO:0051253 48 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
locomotion GO:0040011 313 0.018
developmental process involved in reproduction GO:0003006 27 0.018
protein acetylation GO:0006473 2 0.018
positive regulation of myeloid cell differentiation GO:0045639 2 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
negative regulation of nucleic acid templated transcription GO:1903507 45 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
dna damage checkpoint GO:0000077 6 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
multicellular organism growth GO:0035264 4 0.018
positive regulation of jnk cascade GO:0046330 3 0.018
peptide transport GO:0015833 1 0.018
mitotic sister chromatid cohesion GO:0007064 2 0.017
antimicrobial humoral response GO:0019730 2 0.017
locomotory behavior GO:0007626 34 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
response to chemical GO:0042221 320 0.017
sister chromatid cohesion GO:0007062 2 0.017
striated muscle cell differentiation GO:0051146 129 0.017
behavior GO:0007610 74 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
cellular component morphogenesis GO:0032989 336 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
carboxylic acid metabolic process GO:0019752 22 0.016
muscle organ development GO:0007517 101 0.016
actin filament polymerization GO:0030041 2 0.016
mitotic cell cycle GO:0000278 64 0.016
neuron differentiation GO:0030182 353 0.016
spermatid differentiation GO:0048515 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
negative regulation of dna metabolic process GO:0051053 4 0.015
transmembrane transport GO:0055085 120 0.015
protein import GO:0017038 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
cellular component biogenesis GO:0044085 178 0.015
homeostatic process GO:0042592 142 0.015
negative regulation of protein transport GO:0051224 3 0.015
atp catabolic process GO:0006200 4 0.015
negative regulation of chromosome organization GO:2001251 1 0.014
embryonic organ development GO:0048568 381 0.014
organic acid metabolic process GO:0006082 31 0.014
cellular amine metabolic process GO:0044106 2 0.014
regulation of cytokine production GO:0001817 3 0.014
cell projection assembly GO:0030031 64 0.014
cellular component movement GO:0006928 335 0.014
aging GO:0007568 2 0.014
positive regulation of cell division GO:0051781 2 0.014
cell cycle checkpoint GO:0000075 7 0.014
skeletal muscle tissue development GO:0007519 67 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
cell motility GO:0048870 244 0.013
protein modification process GO:0036211 100 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
gtp metabolic process GO:0046039 4 0.013
ion transmembrane transport GO:0034220 91 0.013
b cell differentiation GO:0030183 1 0.013
cell projection organization GO:0030030 284 0.012
response to other organism GO:0051707 97 0.012
regulation of programmed cell death GO:0043067 101 0.012
regulation of autophagy GO:0010506 3 0.012
negative regulation of histone modification GO:0031057 1 0.012
spermatid development GO:0007286 2 0.012
organelle assembly GO:0070925 110 0.012
regulation of response to stimulus GO:0048583 269 0.012
positive regulation of biological process GO:0048518 253 0.012
intracellular signal transduction GO:0035556 85 0.012
macromolecular complex assembly GO:0065003 35 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
regulation of heart growth GO:0060420 2 0.012
regulation of cell death GO:0010941 103 0.012
apoptotic process GO:0006915 116 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
rna 3 end processing GO:0031123 2 0.012
regulation of erythrocyte differentiation GO:0045646 2 0.012
brain development GO:0007420 293 0.012
regulation of protein complex assembly GO:0043254 3 0.012
cellular protein modification process GO:0006464 100 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
immune system development GO:0002520 191 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
auditory receptor cell fate commitment GO:0009912 4 0.011
regulation of blood vessel size GO:0050880 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
skeletal muscle fiber development GO:0048741 35 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.011
reciprocal dna recombination GO:0035825 1 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
fatty acid transport GO:0015908 1 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
adherens junction assembly GO:0034333 1 0.011
autophagy GO:0006914 4 0.011
positive regulation of transport GO:0051050 2 0.011
multi organism process GO:0051704 134 0.011
fertilization GO:0009566 3 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
response to external biotic stimulus GO:0043207 97 0.011
carbohydrate homeostasis GO:0033500 1 0.010
localization of cell GO:0051674 244 0.010
muscle fiber development GO:0048747 52 0.010
megakaryocyte differentiation GO:0030219 1 0.010
mononuclear cell proliferation GO:0032943 1 0.010
establishment of localization GO:0051234 244 0.010
heme metabolic process GO:0042168 9 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
protein polymerization GO:0051258 4 0.010
specification of symmetry GO:0009799 204 0.010
regulation of dna replication GO:0006275 3 0.010
response to uv GO:0009411 3 0.010
protein localization to membrane GO:0072657 9 0.010
response to endogenous stimulus GO:0009719 83 0.010
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010

tfam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
muscular disease DOID:0080000 0 0.016
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016
myopathy DOID:423 0 0.014
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012
cardiovascular system disease DOID:1287 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011