Danio rerio

10 known processes

otul

OTU like protein

otul biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiosis ii GO:0007135 1 0.443
regulation of multicellular organismal process GO:0051239 277 0.442
regulation of oocyte development GO:0060281 3 0.405
immune system development GO:0002520 191 0.249
oocyte maturation GO:0001556 4 0.248
meiotic nuclear division GO:0007126 4 0.247
regulation of developmental process GO:0050793 247 0.243
organelle fission GO:0048285 23 0.233
cellular biosynthetic process GO:0044249 286 0.205
regulation of cell development GO:0060284 100 0.203
regulation of signaling GO:0023051 235 0.198
regulation of meiotic cell cycle GO:0051445 1 0.193
regulation of cell maturation GO:1903429 1 0.189
positive regulation of cellular biosynthetic process GO:0031328 68 0.186
single organism organelle organization GO:1902589 199 0.183
negative regulation of dna recombination GO:0045910 2 0.177
regulation of primary metabolic process GO:0080090 311 0.171
regulation of metabolic process GO:0019222 359 0.164
hemopoiesis GO:0030097 183 0.162
nuclear division GO:0000280 23 0.147
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.119
digestive tract development GO:0048565 265 0.115
programmed cell death GO:0012501 119 0.112
regulation of response to stimulus GO:0048583 269 0.107
regionalization GO:0003002 274 0.099
regulation of phosphorus metabolic process GO:0051174 43 0.096
cellular macromolecule metabolic process GO:0044260 391 0.096
positive regulation of cellular metabolic process GO:0031325 94 0.095
regulation of mrna processing GO:0050684 3 0.095
sexual reproduction GO:0019953 36 0.095
immune system process GO:0002376 241 0.094
gamete generation GO:0007276 33 0.093
mitotic nuclear division GO:0007067 18 0.093
regulation of signal transduction GO:0009966 225 0.092
oocyte development GO:0048599 14 0.089
defense response to other organism GO:0098542 33 0.084
organic cyclic compound metabolic process GO:1901360 301 0.081
positive regulation of macromolecule metabolic process GO:0010604 93 0.079
regulation of multicellular organismal development GO:2000026 223 0.078
multicellular organismal reproductive process GO:0048609 35 0.078
organic cyclic compound biosynthetic process GO:1901362 223 0.077
positive regulation of cellular catabolic process GO:0031331 3 0.076
negative regulation of cell communication GO:0010648 96 0.076
negative regulation of response to stimulus GO:0048585 104 0.075
regulation of gene expression GO:0010468 265 0.075
organelle organization GO:0006996 227 0.074
pole plasm assembly GO:0007315 4 0.073
axis specification GO:0009798 43 0.072
anterior posterior pattern specification GO:0009952 152 0.071
multi organism process GO:0051704 134 0.071
heterocycle metabolic process GO:0046483 290 0.070
nucleic acid metabolic process GO:0090304 244 0.068
nitrogen compound metabolic process GO:0006807 319 0.067
segmentation GO:0035282 97 0.067
oocyte differentiation GO:0009994 14 0.065
multicellular organism reproduction GO:0032504 35 0.064
regulation of cell differentiation GO:0045595 142 0.064
regulation of mrna catabolic process GO:0061013 3 0.064
cell cycle process GO:0022402 53 0.064
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.063
meiosis i GO:0007127 1 0.063
regulation of cellular metabolic process GO:0031323 320 0.063
regulation of macromolecule biosynthetic process GO:0010556 225 0.062
smad protein complex assembly GO:0007183 1 0.062
spemann organizer formation GO:0060061 10 0.060
cell cycle GO:0007049 93 0.060
meiotic cell cycle process GO:1903046 3 0.058
signal transduction GO:0007165 455 0.057
regulation of protein metabolic process GO:0051246 56 0.056
nucleobase containing compound metabolic process GO:0006139 274 0.056
protein metabolic process GO:0019538 183 0.046
apoptotic process GO:0006915 116 0.046
bmp signaling pathway GO:0030509 52 0.045
mesoderm development GO:0007498 88 0.044
single organism metabolic process GO:0044710 217 0.043
rna biosynthetic process GO:0032774 181 0.042
regulation of transcription dna templated GO:0006355 213 0.042
regulation of phosphate metabolic process GO:0019220 43 0.042
embryonic organ morphogenesis GO:0048562 274 0.041
regulation of biosynthetic process GO:0009889 250 0.041
dna modification GO:0006304 8 0.040
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
single fertilization GO:0007338 3 0.039
regulation of cell activation GO:0050865 1 0.038
negative regulation of cellular process GO:0048523 283 0.037
mitotic cell cycle GO:0000278 64 0.036
male gamete generation GO:0048232 7 0.036
mitochondrion organization GO:0007005 4 0.035
phosphate containing compound metabolic process GO:0006796 108 0.035
microtubule organizing center organization GO:0031023 1 0.035
positive regulation of biosynthetic process GO:0009891 68 0.034
striated muscle cell development GO:0055002 108 0.034
negative regulation of feeding behavior GO:2000252 2 0.034
gastrulation GO:0007369 208 0.033
negative regulation of biological process GO:0048519 304 0.033
positive regulation of gene expression GO:0010628 71 0.033
regulation of chromosome segregation GO:0051983 1 0.033
determination of left right asymmetry in nervous system GO:0035545 4 0.032
female meiotic division GO:0007143 2 0.032
regulation of immune system process GO:0002682 34 0.032
mitotic cell cycle process GO:1903047 48 0.031
positive regulation of cellular process GO:0048522 201 0.031
positive regulation of defense response GO:0031349 9 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
regulation of reproductive process GO:2000241 4 0.030
positive regulation of metabolic process GO:0009893 108 0.029
peptidyl lysine methylation GO:0018022 3 0.029
positive regulation of catabolic process GO:0009896 4 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
spemann organizer formation at the embryonic shield GO:0060063 2 0.029
muscle cell development GO:0055001 115 0.028
positive regulation of protein metabolic process GO:0051247 23 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
liver development GO:0001889 96 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
nucleic acid templated transcription GO:0097659 181 0.028
defense response GO:0006952 47 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.027
rna stabilization GO:0043489 4 0.027
negative regulation of signal transduction GO:0009968 94 0.027
positive regulation of biological process GO:0048518 253 0.027
cell projection organization GO:0030030 284 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
positive regulation of cell cycle GO:0045787 3 0.026
aging GO:0007568 2 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
positive regulation of mrna metabolic process GO:1903313 2 0.025
activation of mapk activity GO:0000187 3 0.025
vasculature development GO:0001944 278 0.025
cellular component morphogenesis GO:0032989 336 0.025
biosynthetic process GO:0009058 294 0.024
regulation of cytokine production GO:0001817 3 0.024
apoptotic process involved in development GO:1902742 2 0.024
germ cell migration GO:0008354 8 0.024
camera type eye morphogenesis GO:0048593 108 0.024
translational initiation GO:0006413 3 0.023
spermatogenesis GO:0007283 7 0.023
digestive tract morphogenesis GO:0048546 231 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
determination of dorsal identity GO:0048263 13 0.023
regulation of gene expression epigenetic GO:0040029 11 0.023
spindle assembly involved in female meiosis GO:0007056 1 0.023
single organism reproductive process GO:0044702 40 0.023
epithelial cell differentiation GO:0030855 116 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
regulation of innate immune response GO:0045088 11 0.023
male meiosis GO:0007140 2 0.023
centrosome organization GO:0051297 1 0.022
response to chemical GO:0042221 320 0.022
positive regulation of developmental process GO:0051094 50 0.022
meiotic chromosome segregation GO:0045132 3 0.022
dna alkylation GO:0006305 8 0.022
response to biotic stimulus GO:0009607 97 0.022
cellular protein metabolic process GO:0044267 129 0.022
3 utr mediated mrna stabilization GO:0070935 3 0.021
response to stress GO:0006950 263 0.021
response to external stimulus GO:0009605 264 0.021
cellular localization GO:0051641 97 0.021
maintenance of location GO:0051235 4 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of defense response GO:0031347 14 0.021
fin regeneration GO:0031101 51 0.021
phosphorylation GO:0016310 69 0.020
negative regulation of kinase activity GO:0033673 4 0.020
hepaticobiliary system development GO:0061008 98 0.020
negative regulation of gene silencing GO:0060969 1 0.020
regulation of cell death GO:0010941 103 0.020
negative regulation of gene expression GO:0010629 65 0.020
positive regulation of translation GO:0045727 1 0.019
regulation of cell cycle process GO:0010564 20 0.019
gene expression GO:0010467 252 0.019
phosphorus metabolic process GO:0006793 109 0.019
positive regulation of cell division GO:0051781 2 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
cell death GO:0008219 121 0.019
regulation of apoptotic process GO:0042981 98 0.018
cellular component biogenesis GO:0044085 178 0.018
regulation of programmed cell death GO:0043067 101 0.018
blood vessel morphogenesis GO:0048514 216 0.018
cellular protein modification process GO:0006464 100 0.018
multicellular organism growth GO:0035264 4 0.018
developmental maturation GO:0021700 34 0.018
regulation of phosphorylation GO:0042325 26 0.017
macromolecule modification GO:0043412 111 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
germ cell development GO:0007281 22 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
oocyte construction GO:0007308 5 0.017
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.017
regulation of cell communication GO:0010646 232 0.017
angiogenesis GO:0001525 158 0.016
dorsal ventral axis specification GO:0009950 14 0.016
developmental growth GO:0048589 166 0.016
axon extension GO:0048675 45 0.016
chromatin organization GO:0006325 22 0.016
positive regulation of transcription dna templated GO:0045893 57 0.016
posttranscriptional gene silencing by rna GO:0035194 3 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
germ line stem cell maintenance GO:0030718 2 0.015
rna metabolic process GO:0016070 219 0.015
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.015
cellular component movement GO:0006928 335 0.015
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.015
protein modification process GO:0036211 100 0.015
cell morphogenesis GO:0000902 289 0.015
skeletal system development GO:0001501 181 0.015
mrna stabilization GO:0048255 4 0.014
regulation of protein catabolic process GO:0042176 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
determination of bilateral symmetry GO:0009855 204 0.014
response to bacterium GO:0009617 58 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
system process GO:0003008 185 0.014
death GO:0016265 121 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
heterocycle biosynthetic process GO:0018130 215 0.013
multi organism reproductive process GO:0044703 36 0.013
response to other organism GO:0051707 97 0.013
determination of left right symmetry GO:0007368 179 0.013
regulation of dna recombination GO:0000018 2 0.013
determination of dorsal ventral asymmetry GO:0048262 34 0.013
negative regulation of cell death GO:0060548 60 0.013
spermatid development GO:0007286 2 0.013
endodermal cell fate determination GO:0007493 2 0.013
stem cell maintenance GO:0019827 4 0.012
regulation of hormone levels GO:0010817 21 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
female sex differentiation GO:0046660 4 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.012
mesenchyme development GO:0060485 127 0.012
spindle assembly GO:0051225 2 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
methylation GO:0032259 22 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
reciprocal meiotic recombination GO:0007131 1 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
transcription dna templated GO:0006351 181 0.012
localization of cell GO:0051674 244 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
cell motility GO:0048870 244 0.011
reproduction GO:0000003 40 0.011
regulation of embryonic development GO:0045995 47 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
locomotion GO:0040011 313 0.011
regulation of inflammatory response GO:0050727 2 0.011
muscle cell differentiation GO:0042692 139 0.011
cell aging GO:0007569 2 0.011
muscle structure development GO:0061061 196 0.011
epiboly GO:0090504 41 0.011
hepatic duct development GO:0061011 2 0.011
defense response to bacterium GO:0042742 22 0.011
germ line stem cell division GO:0042078 1 0.011
growth GO:0040007 174 0.010
regulation of endodermal cell fate specification GO:0042663 15 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.010
intracellular mrna localization GO:0008298 1 0.010
pigment granule organization GO:0048753 4 0.010
meiotic cell cycle GO:0051321 5 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
dna methylation GO:0006306 8 0.010

otul disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.078
reproductive system disease DOID:15 0 0.078
congenital hypoplastic anemia DOID:1342 0 0.035
immune system disease DOID:2914 0 0.035
aplastic anemia DOID:12449 0 0.035
bone marrow disease DOID:4961 0 0.035
anemia DOID:2355 0 0.035
hematopoietic system disease DOID:74 0 0.035
nervous system disease DOID:863 0 0.010