Danio rerio

0 known processes

rabgef1

RAB guanine nucleotide exchange factor (GEF) 1

(Aliases: MGC65944,MGC173958,zgc:65944)

rabgef1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 3 0.133
cellular protein catabolic process GO:0044257 4 0.122
larval development GO:0002164 2 0.089
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.083
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.078
modification dependent macromolecule catabolic process GO:0043632 3 0.064
proteasomal protein catabolic process GO:0010498 2 0.063
ubiquitin dependent protein catabolic process GO:0006511 3 0.061
aging GO:0007568 2 0.056
transport GO:0006810 220 0.040
multicellular organism growth GO:0035264 4 0.036
regulation of protein complex assembly GO:0043254 3 0.034
establishment of synaptic vesicle localization GO:0097480 1 0.034
negative regulation of catabolic process GO:0009895 3 0.033
protein import GO:0017038 3 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.031
sensory organ development GO:0007423 393 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.029
epithelial tube morphogenesis GO:0060562 148 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
eye development GO:0001654 277 0.027
heart morphogenesis GO:0003007 156 0.027
cell migration GO:0016477 237 0.026
positive regulation of catabolic process GO:0009896 4 0.025
protein targeting to membrane GO:0006612 1 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
toxin transport GO:1901998 2 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
protein n linked glycosylation GO:0006487 1 0.025
regulation of synapse assembly GO:0051963 3 0.025
tube morphogenesis GO:0035239 349 0.024
cellular lipid catabolic process GO:0044242 3 0.023
heart development GO:0007507 313 0.023
regulation of developmental process GO:0050793 247 0.023
establishment of localization GO:0051234 244 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
heart looping GO:0001947 94 0.023
regulation of synapse organization GO:0050807 3 0.023
positive regulation of transport GO:0051050 2 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
fatty acid catabolic process GO:0009062 1 0.022
amine metabolic process GO:0009308 2 0.022
regulation of cell communication GO:0010646 232 0.022
immune system process GO:0002376 241 0.021
protein k48 linked ubiquitination GO:0070936 1 0.021
glycoprotein biosynthetic process GO:0009101 21 0.021
regulation of protein catabolic process GO:0042176 1 0.021
regulation of binding GO:0051098 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cellular response to oxygen levels GO:0071453 1 0.021
cellular response to hypoxia GO:0071456 1 0.020
cellular amine metabolic process GO:0044106 2 0.020
embryonic organ development GO:0048568 381 0.020
regulation of protein transport GO:0051223 3 0.020
cellular biosynthetic process GO:0044249 286 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
carboxylic acid catabolic process GO:0046395 3 0.020
regulation of reproductive process GO:2000241 4 0.019
positive regulation of chromatin modification GO:1903310 1 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
determination of left right symmetry GO:0007368 179 0.019
protein localization to plasma membrane GO:0072659 1 0.019
tube closure GO:0060606 1 0.019
response to organic substance GO:0010033 153 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
single organism metabolic process GO:0044710 217 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
adult behavior GO:0030534 2 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
synaptic vesicle transport GO:0048489 1 0.018
camera type eye development GO:0043010 222 0.018
negative regulation of response to cytokine stimulus GO:0060761 2 0.018
neuromast development GO:0048884 46 0.018
regulation of biological quality GO:0065008 263 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
mitochondrion organization GO:0007005 4 0.017
response to chemical GO:0042221 320 0.017
maintenance of location GO:0051235 4 0.017
negative regulation of kinase activity GO:0033673 4 0.017
response to drug GO:0042493 3 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
positive regulation of blood circulation GO:1903524 2 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.016
cell morphogenesis GO:0000902 289 0.016
retina development in camera type eye GO:0060041 146 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
negative regulation of defense response GO:0031348 2 0.016
specification of symmetry GO:0009799 204 0.016
synaptic vesicle localization GO:0097479 1 0.016
response to stress GO:0006950 263 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
lipid catabolic process GO:0016042 4 0.016
phagocytosis GO:0006909 3 0.016
response to vitamin GO:0033273 3 0.016
peptidyl threonine modification GO:0018210 1 0.016
lipid storage GO:0019915 1 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
organic substance biosynthetic process GO:1901576 289 0.015
nuclear import GO:0051170 3 0.015
primary neural tube formation GO:0014020 1 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
somatic muscle development GO:0007525 4 0.015
regulation of tube size GO:0035150 2 0.015
regulation of inflammatory response GO:0050727 2 0.015
regulation of blood vessel size GO:0050880 2 0.015
cell substrate adhesion GO:0031589 4 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
oxoacid metabolic process GO:0043436 31 0.015
forebrain cell migration GO:0021885 1 0.015
protein stabilization GO:0050821 2 0.015
regulation of response to stimulus GO:0048583 269 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
dna templated transcription initiation GO:0006352 1 0.015
protein import into nucleus GO:0006606 3 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
regulation of transporter activity GO:0032409 2 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
digestive tract development GO:0048565 265 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
vasculature development GO:0001944 278 0.014
small molecule catabolic process GO:0044282 3 0.014
fatty acid beta oxidation GO:0006635 1 0.014
regulation of organ growth GO:0046620 3 0.014
axon development GO:0061564 166 0.014
multicellular organismal metabolic process GO:0044236 2 0.014
positive regulation of epithelial cell proliferation GO:0050679 1 0.014
monocarboxylic acid catabolic process GO:0072329 3 0.014
dicarboxylic acid transport GO:0006835 1 0.014
digestive tract mesoderm development GO:0007502 1 0.014
protein targeting to nucleus GO:0044744 3 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
response to amino acid GO:0043200 2 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
biosynthetic process GO:0009058 294 0.014
myeloid cell development GO:0061515 32 0.013
cellular response to nutrient levels GO:0031669 2 0.013
regulation of gtpase activity GO:0043087 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
response to hexose GO:0009746 3 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
signal transduction GO:0007165 455 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
regulation of oocyte development GO:0060281 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
response to nutrient GO:0007584 3 0.013
response to glucose GO:0009749 3 0.013
cellular macromolecule metabolic process GO:0044260 391 0.013
protein metabolic process GO:0019538 183 0.013
protein homooligomerization GO:0051260 3 0.013
glycoprotein metabolic process GO:0009100 23 0.013
membrane organization GO:0061024 21 0.013
blood vessel development GO:0001568 246 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
carbohydrate derivative biosynthetic process GO:1901137 43 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
macromolecule glycosylation GO:0043413 9 0.013
negative regulation of immune response GO:0050777 2 0.013
gtp metabolic process GO:0046039 4 0.013
positive regulation of cell cycle GO:0045787 3 0.012
regulation of signaling GO:0023051 235 0.012
response to carbohydrate GO:0009743 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of cell shape GO:0008360 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
gtp catabolic process GO:0006184 2 0.012
homeostatic process GO:0042592 142 0.012
olfactory lobe development GO:0021988 4 0.012
tissue remodeling GO:0048771 4 0.012
nuclear transport GO:0051169 4 0.012
regulation of synaptic plasticity GO:0048167 1 0.011
lipid oxidation GO:0034440 1 0.011
amino acid transport GO:0006865 2 0.011
b cell activation GO:0042113 2 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of mrna processing GO:0050684 3 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
meiotic nuclear division GO:0007126 4 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
brain development GO:0007420 293 0.011
regulation of protein targeting GO:1903533 2 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
oxidation reduction process GO:0055114 41 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
erythrocyte differentiation GO:0030218 54 0.011
catabolic process GO:0009056 32 0.011
macromolecule catabolic process GO:0009057 15 0.011
meiotic cell cycle process GO:1903046 3 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
small molecule metabolic process GO:0044281 77 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
positive regulation of histone modification GO:0031058 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of translation GO:0045727 1 0.011
localization of cell GO:0051674 244 0.011
transmembrane transport GO:0055085 120 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
carbohydrate metabolic process GO:0005975 12 0.010
sensory perception of smell GO:0007608 2 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
cellular protein metabolic process GO:0044267 129 0.010
negative regulation of biological process GO:0048519 304 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
response to monosaccharide GO:0034284 3 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.010
blood vessel morphogenesis GO:0048514 216 0.010
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
single organism transport GO:0044765 206 0.010
positive regulation of oocyte development GO:0060282 1 0.010
single organism nuclear import GO:1902593 3 0.010
eye morphogenesis GO:0048592 144 0.010

rabgef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.011