Danio rerio

17 known processes

lhx5

LIM homeobox 5

(Aliases: MGC109837,lim5)

lhx5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.989
chordate embryonic development GO:0043009 271 0.976
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.973
Mouse Fly
nucleic acid templated transcription GO:0097659 181 0.959
Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.955
Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.953
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.952
Mouse Fly
forebrain neuron fate commitment GO:0021877 1 0.951
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.951
Mouse Fly
rna biosynthetic process GO:0032774 181 0.947
Mouse Fly
neuron fate commitment GO:0048663 26 0.943
Zebrafish
brain development GO:0007420 293 0.942
aromatic compound biosynthetic process GO:0019438 217 0.941
Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.936
Mouse Fly
neural tube development GO:0021915 62 0.932
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.918
Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.906
Fly
biosynthetic process GO:0009058 294 0.899
Mouse Fly
central nervous system neuron differentiation GO:0021953 74 0.898
Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 213 0.893
Mouse Fly
larval development GO:0002164 2 0.882
Worm
organic substance biosynthetic process GO:1901576 289 0.879
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.878
Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.870
Mouse Fly
heterocycle metabolic process GO:0046483 290 0.868
Mouse Fly
neuron projection guidance GO:0097485 86 0.868
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.860
regulation of biosynthetic process GO:0009889 250 0.859
Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.848
Mouse Fly
diencephalon development GO:0021536 58 0.839
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.837
Mouse Fly
cell differentiation in spinal cord GO:0021515 40 0.830
Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.825
Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.811
ventral spinal cord development GO:0021517 35 0.806
Zebrafish
embryonic organ development GO:0048568 381 0.805
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.801
Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.791
Mouse Fly
forebrain development GO:0030900 96 0.789
axon guidance GO:0007411 86 0.780
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.779
Zebrafish
thalamus development GO:0021794 6 0.774
Zebrafish
head development GO:0060322 303 0.768
cellular biosynthetic process GO:0044249 286 0.762
Mouse Fly
neuron projection development GO:0031175 180 0.760
Zebrafish Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.753
Mouse Fly
neuron differentiation GO:0030182 353 0.753
Zebrafish Mouse Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.745
Mouse Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.731
regulation of transcription dna templated GO:0006355 213 0.728
Mouse Fly
neuron fate specification GO:0048665 20 0.723
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.715
cell fate specification GO:0001708 68 0.712
Zebrafish Worm
generation of neurons GO:0048699 385 0.703
Zebrafish Mouse Worm
regulation of rna metabolic process GO:0051252 224 0.693
Mouse Fly
gabaergic neuron differentiation GO:0097154 2 0.691
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.687
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.684
Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.682
Mouse Fly
ventral midline development GO:0007418 13 0.680
oligodendrocyte cell fate specification GO:0021778 4 0.671
negative regulation of biological process GO:0048519 304 0.666
Fly
digestive system development GO:0055123 289 0.663
Zebrafish
transcription dna templated GO:0006351 181 0.662
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.661
Mouse Fly
embryonic skeletal system development GO:0048706 97 0.651
morphogenesis of an epithelium GO:0002009 333 0.650
Zebrafish
cell motility GO:0048870 244 0.635
Worm
regulation of gene expression GO:0010468 265 0.634
Zebrafish Mouse Fly
epidermal cell fate specification GO:0009957 4 0.630
locomotion GO:0040011 313 0.619
Zebrafish Worm
positive regulation of cellular metabolic process GO:0031325 94 0.617
Mouse Fly
positive regulation of biosynthetic process GO:0009891 68 0.606
Mouse Fly
eye development GO:0001654 277 0.600
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.593
cell migration GO:0016477 237 0.586
Worm
chemotaxis GO:0006935 104 0.580
Zebrafish
peripheral nervous system development GO:0007422 55 0.579
Zebrafish
fourth ventricle development GO:0021592 8 0.578
Zebrafish
forebrain regionalization GO:0021871 4 0.577
regulation of nitrogen compound metabolic process GO:0051171 251 0.571
Mouse Fly
regulation of metabolic process GO:0019222 359 0.566
Zebrafish Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.561
Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.560
Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.554
camera type eye development GO:0043010 222 0.552
Zebrafish
gene expression GO:0010467 252 0.550
Zebrafish Mouse Fly
forebrain generation of neurons GO:0021872 14 0.538
Mouse
axonogenesis GO:0007409 152 0.536
Zebrafish
regionalization GO:0003002 274 0.533
Zebrafish Fly
forebrain neuron differentiation GO:0021879 14 0.531
Mouse
mesenchymal cell development GO:0014031 78 0.529
embryonic camera type eye morphogenesis GO:0048596 19 0.529
Zebrafish
regulation of response to stimulus GO:0048583 269 0.528
sensory organ morphogenesis GO:0090596 200 0.515
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.508
Zebrafish Mouse Fly
optokinetic behavior GO:0007634 9 0.507
Zebrafish
cardiocyte differentiation GO:0035051 44 0.506
Zebrafish
dopaminergic neuron differentiation GO:0071542 14 0.501
rna metabolic process GO:0016070 219 0.496
Mouse Fly
digestive tract development GO:0048565 265 0.493
positive regulation of gene expression GO:0010628 71 0.481
Mouse Fly
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.481
taxis GO:0042330 109 0.472
Zebrafish
cell morphogenesis GO:0000902 289 0.470
Zebrafish
midbrain hindbrain boundary development GO:0030917 23 0.467
Zebrafish
ear development GO:0043583 127 0.457
Zebrafish
multicellular organism growth GO:0035264 4 0.451
pancreatic a cell development GO:0003322 2 0.450
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.449
Mouse Fly
ventricular system development GO:0021591 12 0.437
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.436
Mouse Fly
axon development GO:0061564 166 0.436
Zebrafish Worm
regulation of primary metabolic process GO:0080090 311 0.431
Mouse Fly
spinal cord development GO:0021510 46 0.429
Zebrafish Mouse
cell differentiation in hindbrain GO:0021533 5 0.416
Mouse
cell proliferation in forebrain GO:0021846 3 0.407
Mouse
glial cell fate specification GO:0021780 4 0.399
anterior posterior pattern specification GO:0009952 152 0.395
Zebrafish
cellular component movement GO:0006928 335 0.395
Zebrafish Worm
spinal cord motor neuron differentiation GO:0021522 26 0.392
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.389
embryonic camera type eye formation GO:0060900 10 0.373
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.373
abducens nucleus development GO:0021742 2 0.367
dorsal ventral pattern formation GO:0009953 125 0.361
positive regulation of nucleic acid templated transcription GO:1903508 57 0.353
Mouse Fly
sensory organ development GO:0007423 393 0.343
regulation of developmental process GO:0050793 247 0.339
Mouse Worm
photoreceptor cell fate commitment GO:0046552 1 0.333
ventral spinal cord interneuron differentiation GO:0021514 12 0.332
cardiac chamber formation GO:0003207 4 0.330
regulation of multicellular organismal process GO:0051239 277 0.325
Zebrafish Mouse Worm
rostrocaudal neural tube patterning GO:0021903 29 0.324
Zebrafish
epidermal cell differentiation GO:0009913 36 0.321
Zebrafish
positive regulation of cellular process GO:0048522 201 0.321
Mouse Fly
neuron projection morphogenesis GO:0048812 161 0.321
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.317
Mouse Fly
mesodermal cell fate specification GO:0007501 12 0.303
anterior commissure morphogenesis GO:0021960 3 0.296
embryonic eye morphogenesis GO:0048048 30 0.292
Zebrafish
negative regulation of nucleic acid templated transcription GO:1903507 45 0.292
Fly
inner ear morphogenesis GO:0042472 63 0.291
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.291
Mouse Fly
embryonic organ morphogenesis GO:0048562 274 0.284
Zebrafish
regulation of cell differentiation GO:0045595 142 0.282
Worm
tube morphogenesis GO:0035239 349 0.276
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.272
Zebrafish
ear morphogenesis GO:0042471 64 0.268
Zebrafish
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.265
Fly
mesenchymal cell differentiation GO:0048762 87 0.264
neuroblast fate determination GO:0007400 1 0.256
neural tube patterning GO:0021532 33 0.255
Zebrafish
cell fate commitment GO:0045165 99 0.253
Zebrafish Worm
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.252
Zebrafish
pancreas development GO:0031016 84 0.248
Zebrafish
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.247
Fly
central nervous system neuron axonogenesis GO:0021955 18 0.238
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.235
Zebrafish
neuromast mantle cell differentiation GO:0048888 1 0.231
response to organic substance GO:0010033 153 0.231
cell projection organization GO:0030030 284 0.225
Zebrafish Worm
hindbrain development GO:0030902 91 0.224
Zebrafish Mouse
optomotor response GO:0071632 1 0.223
Zebrafish
ventral spinal cord interneuron fate commitment GO:0060579 3 0.218
notochord development GO:0030903 54 0.213
pharyngeal muscle development GO:0043282 4 0.213
response to external stimulus GO:0009605 264 0.208
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.204
positive regulation of biological process GO:0048518 253 0.202
Mouse Worm Fly
specification of symmetry GO:0009799 204 0.199
positive regulation of rna biosynthetic process GO:1902680 57 0.196
Mouse Fly
inner ear development GO:0048839 126 0.195
Zebrafish
negative regulation of rna metabolic process GO:0051253 48 0.195
Fly
maintenance of location GO:0051235 4 0.194
response to stress GO:0006950 263 0.194
regulation of mechanoreceptor differentiation GO:0045631 1 0.193
stem cell differentiation GO:0048863 117 0.192
sympathetic nervous system development GO:0048485 3 0.191
proximal distal pattern formation GO:0009954 1 0.190
Fly
skeletal system development GO:0001501 181 0.186
glial cell fate commitment GO:0021781 6 0.183
heart development GO:0007507 313 0.183
Zebrafish
type b pancreatic cell differentiation GO:0003309 8 0.182
Zebrafish
regulation of neurogenesis GO:0050767 87 0.179
negative regulation of metabolic process GO:0009892 86 0.179
Fly
regulation of multicellular organismal development GO:2000026 223 0.178
Mouse Worm
pancreatic d cell differentiation GO:0003311 2 0.178
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.176
Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.169
Fly
central nervous system myelin formation GO:0032289 1 0.168
cardiac muscle cell differentiation GO:0055007 30 0.162
Zebrafish
ectoderm formation GO:0001705 2 0.162
mammillary body development GO:0021767 4 0.162
mechanoreceptor differentiation GO:0042490 37 0.159
Zebrafish
neuron development GO:0048666 262 0.159
Zebrafish Worm
negative regulation of gene expression GO:0010629 65 0.158
Fly
cell part morphogenesis GO:0032990 246 0.157
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.155
Fly
neuroblast differentiation GO:0014016 1 0.155
endocrine pancreas development GO:0031018 27 0.154
Zebrafish
regulation of cardiac chamber formation GO:1901210 2 0.152
mesenchyme development GO:0060485 127 0.151
stem cell fate determination GO:0048867 1 0.149
enteroendocrine cell differentiation GO:0035883 9 0.148
Zebrafish
somite development GO:0061053 96 0.147
determination of bilateral symmetry GO:0009855 204 0.145
heart looping GO:0001947 94 0.145
pituitary gland development GO:0021983 16 0.144
retina morphogenesis in camera type eye GO:0060042 79 0.142
pigmentation GO:0043473 85 0.142
auditory receptor cell development GO:0060117 8 0.142
Zebrafish
muscle structure development GO:0061061 196 0.139
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.138
hair cell differentiation GO:0035315 32 0.136
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.134
positive regulation of transcription dna templated GO:0045893 57 0.134
Mouse Fly
negative regulation of biosynthetic process GO:0009890 55 0.133
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.133
Fly
mesodermal cell fate commitment GO:0001710 14 0.133
ectodermal placode formation GO:0060788 26 0.132
cell projection morphogenesis GO:0048858 244 0.131
Zebrafish
neural crest cell differentiation GO:0014033 72 0.131
facial nucleus development GO:0021754 7 0.130
cell proliferation in hindbrain GO:0021534 4 0.129
type b pancreatic cell development GO:0003323 4 0.129
Zebrafish
growth GO:0040007 174 0.128
Zebrafish
skin development GO:0043588 54 0.127
Zebrafish
catechol containing compound biosynthetic process GO:0009713 2 0.127
regulation of inner ear receptor cell differentiation GO:2000980 1 0.126
gland development GO:0048732 143 0.125
dna templated transcription initiation GO:0006352 1 0.122
endoderm development GO:0007492 49 0.121
positive regulation of gastrulation GO:2000543 2 0.119
stem cell development GO:0048864 82 0.119
single organism localization GO:1902578 225 0.117
negative regulation of macromolecule metabolic process GO:0010605 76 0.115
Fly
mesoderm morphogenesis GO:0048332 51 0.115
retina development in camera type eye GO:0060041 146 0.114
Zebrafish
anterior head development GO:0097065 2 0.112
multi organism process GO:0051704 134 0.112
Worm
regulation of cell communication GO:0010646 232 0.112
negative regulation of rna biosynthetic process GO:1902679 45 0.110
Fly
inner ear receptor cell differentiation GO:0060113 29 0.110
Zebrafish
developmental growth GO:0048589 166 0.109
Zebrafish
regulation of cell development GO:0060284 100 0.109
auditory receptor cell fate commitment GO:0009912 4 0.108
brain morphogenesis GO:0048854 18 0.107
behavior GO:0007610 74 0.106
Zebrafish Worm
localization of cell GO:0051674 244 0.105
Worm
neural precursor cell proliferation GO:0061351 20 0.104
Mouse
gastrulation GO:0007369 208 0.101
regulation of stem cell proliferation GO:0072091 2 0.101
apoptotic process involved in development GO:1902742 2 0.097
axial mesodermal cell fate specification GO:0048327 3 0.097
regulation of anterior head development GO:2000742 2 0.095
embryonic camera type eye development GO:0031076 29 0.094
Zebrafish
formation of primary germ layer GO:0001704 62 0.094
developmental programmed cell death GO:0010623 4 0.093
cerebellar cortex development GO:0021695 5 0.093
Mouse
limbic system development GO:0021761 16 0.089
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.089
atrioventricular valve formation GO:0003190 3 0.089
endocrine process GO:0050886 2 0.088
central nervous system myelination GO:0022010 2 0.088
pancreatic a cell differentiation GO:0003310 6 0.088
Zebrafish
wound healing GO:0042060 90 0.087
regulation of multicellular organism growth GO:0040014 4 0.087
regulation of response to nutrient levels GO:0032107 1 0.086
autonomic nervous system development GO:0048483 19 0.086
lipid storage GO:0019915 1 0.084
nucleocytoplasmic transport GO:0006913 4 0.083
neural plate pattern specification GO:0060896 12 0.083
motor neuron axon guidance GO:0008045 23 0.082
stem cell proliferation GO:0072089 4 0.082
regulation of neural precursor cell proliferation GO:2000177 3 0.081
Mouse
epithelial cell migration GO:0010631 25 0.081
nephron tubule epithelial cell differentiation GO:0072160 1 0.081
positive regulation of stem cell proliferation GO:2000648 1 0.078
retina layer formation GO:0010842 24 0.078
oligodendrocyte cell fate commitment GO:0021779 5 0.078
regulation of signal transduction GO:0009966 225 0.077
axon extension GO:0048675 45 0.077
Zebrafish
segmentation GO:0035282 97 0.076
regulation of stem cell differentiation GO:2000736 4 0.076
muscle cell differentiation GO:0042692 139 0.073
Zebrafish
telencephalon development GO:0021537 14 0.073
Zebrafish Mouse
epithelial to mesenchymal transition GO:0001837 21 0.072
water homeostasis GO:0030104 4 0.071
system process GO:0003008 185 0.071
Zebrafish
somitogenesis GO:0001756 87 0.070
semicircular canal development GO:0060872 24 0.068
Zebrafish
embryonic heart tube development GO:0035050 133 0.068
neural tube formation GO:0001841 16 0.068
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.068
single organism nuclear import GO:1902593 3 0.068
connective tissue development GO:0061448 99 0.067
neural crest cell development GO:0014032 62 0.067
positive regulation of neuron migration GO:2001224 2 0.067
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.067
negative regulation of cellular process GO:0048523 283 0.067
Fly
determination of heart left right asymmetry GO:0061371 117 0.066
immune system process GO:0002376 241 0.066
cellular component morphogenesis GO:0032989 336 0.066
Zebrafish
exocrine pancreas development GO:0031017 28 0.066
Zebrafish
epithelial cell differentiation GO:0030855 116 0.065
Zebrafish
pancreatic d cell development GO:0003324 1 0.065
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.065
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.065
midbrain development GO:0030901 28 0.063
epithalamus development GO:0021538 10 0.062
regulation of heart morphogenesis GO:2000826 17 0.060
angiogenesis GO:0001525 158 0.060
regulation of nervous system development GO:0051960 90 0.060
Mouse
nephron tubule morphogenesis GO:0072078 1 0.059
retinal cell programmed cell death GO:0046666 2 0.059
forebrain neuron development GO:0021884 7 0.059
negative regulation of response to stimulus GO:0048585 104 0.058
adult behavior GO:0030534 2 0.058
visual behavior GO:0007632 10 0.058
Zebrafish
glandular epithelial cell differentiation GO:0002067 9 0.058
Zebrafish
glial cell fate determination GO:0007403 1 0.058
negative regulation of mesodermal cell fate specification GO:0042662 3 0.057
protein import into nucleus GO:0006606 3 0.056
neural plate anterior posterior regionalization GO:0021999 8 0.055
habenula development GO:0021986 9 0.055
regulation of neuron differentiation GO:0045664 56 0.055
regulation of mesoderm development GO:2000380 11 0.054
regulation of epithelial cell proliferation GO:0050678 3 0.054
neuroblast fate commitment GO:0014017 1 0.054
nuclear import GO:0051170 3 0.053
neural crest cell migration GO:0001755 42 0.053
keratinocyte differentiation GO:0030216 0 0.053
regulation of biological quality GO:0065008 263 0.053
regulation of cell proliferation GO:0042127 37 0.053
Mouse
muscle tissue development GO:0060537 110 0.053
Zebrafish
peripheral nervous system neuron differentiation GO:0048934 28 0.053
Zebrafish
response to wounding GO:0009611 116 0.052
forebrain dorsal ventral pattern formation GO:0021798 1 0.052
signal transduction GO:0007165 455 0.051
apoptotic process involved in morphogenesis GO:0060561 2 0.051
embryonic heart tube morphogenesis GO:0003143 108 0.051
forebrain morphogenesis GO:0048853 6 0.051
determination of left right symmetry GO:0007368 179 0.050
aging GO:0007568 2 0.050
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.050
determination of dorsal ventral asymmetry GO:0048262 34 0.049
glial cell migration GO:0008347 3 0.049
response to external biotic stimulus GO:0043207 97 0.049
female sex differentiation GO:0046660 4 0.049
negative regulation of cell communication GO:0010648 96 0.048
cellular response to endogenous stimulus GO:0071495 68 0.048
tissue regeneration GO:0042246 74 0.048
peripheral nervous system neuron development GO:0048935 22 0.048
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.047
heart morphogenesis GO:0003007 156 0.047
paraxial mesoderm development GO:0048339 8 0.047
stem cell fate commitment GO:0048865 1 0.046
gliogenesis GO:0042063 45 0.046
cell proliferation GO:0008283 80 0.046
Mouse
catecholamine biosynthetic process GO:0042423 2 0.045
convergent extension GO:0060026 118 0.045
central nervous system neuron development GO:0021954 29 0.045
hatching gland development GO:0048785 3 0.045
oligodendrocyte differentiation GO:0048709 23 0.045
pons development GO:0021548 11 0.044
epidermis development GO:0008544 48 0.044
Zebrafish
ventral spinal cord interneuron specification GO:0021521 3 0.044
cell proliferation in midbrain GO:0033278 4 0.043
endocrine system development GO:0035270 65 0.043
Zebrafish
primary neural tube formation GO:0014020 1 0.042
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.042
nuclear transport GO:0051169 4 0.042
inner ear receptor cell fate commitment GO:0060120 4 0.042
neuron migration GO:0001764 22 0.042
negative regulation of stem cell differentiation GO:2000737 2 0.042
neuron projection extension GO:1990138 45 0.042
Zebrafish
positive regulation of cell proliferation GO:0008284 15 0.041
Mouse
positive regulation of catabolic process GO:0009896 4 0.041
bmp signaling pathway GO:0030509 52 0.040
regulation of bmp signaling pathway GO:0030510 39 0.040
forebrain anterior posterior pattern specification GO:0021797 3 0.040
paraxial mesoderm morphogenesis GO:0048340 2 0.040
axis specification GO:0009798 43 0.040
regulation of cardiac chamber morphogenesis GO:1901219 2 0.039
cardiac muscle tissue development GO:0048738 48 0.039
Zebrafish
stem cell maintenance GO:0019827 4 0.039
diencephalon morphogenesis GO:0048852 5 0.038
regulation of cellular protein metabolic process GO:0032268 52 0.038
response to other organism GO:0051707 97 0.037
neural nucleus development GO:0048857 15 0.037
optic placode formation GO:0001743 4 0.037
nephron epithelium morphogenesis GO:0072088 1 0.036
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.036
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.036
Fly
embryonic hemopoiesis GO:0035162 53 0.036
motor neuron migration GO:0097475 4 0.036
canonical wnt signaling pathway GO:0060070 48 0.036
post anal tail morphogenesis GO:0036342 19 0.035
otic placode formation GO:0043049 23 0.035
phenol containing compound biosynthetic process GO:0046189 4 0.035
protein targeting to nucleus GO:0044744 3 0.035
cellular response to chemical stimulus GO:0070887 157 0.034
regulation of cellular component organization GO:0051128 86 0.034
optic nerve development GO:0021554 15 0.034
Zebrafish
negative regulation of wnt signaling pathway GO:0030178 30 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
programmed cell death GO:0012501 119 0.034
regulation of organ morphogenesis GO:2000027 35 0.033
morphogenesis of embryonic epithelium GO:0016331 30 0.033
Zebrafish
urogenital system development GO:0001655 97 0.032
Zebrafish
blood circulation GO:0008015 87 0.032
Zebrafish
spinal cord motor neuron cell fate specification GO:0021520 8 0.032
single organism reproductive process GO:0044702 40 0.032
vasculature development GO:0001944 278 0.032
positive regulation of embryonic development GO:0040019 3 0.032
foregut morphogenesis GO:0007440 4 0.032
protein metabolic process GO:0019538 183 0.031
central nervous system projection neuron axonogenesis GO:0021952 15 0.031
cardiac cell fate commitment GO:0060911 1 0.031
regulation of localization GO:0032879 104 0.031
Worm
convergent extension involved in organogenesis GO:0060029 10 0.031
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.031
regulation of binding GO:0051098 3 0.031
lateral line ganglion development GO:0048890 2 0.031
heart contraction GO:0060047 71 0.031
Zebrafish
post embryonic morphogenesis GO:0009886 4 0.030
Fly
death GO:0016265 121 0.030
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.030
sensory epithelium regeneration GO:0070654 14 0.030
otic vesicle formation GO:0030916 27 0.030
developmental growth involved in morphogenesis GO:0060560 86 0.029
Zebrafish
regulation of cell morphogenesis GO:0022604 42 0.029
regulation of gastrulation GO:0010470 24 0.029
mesoderm formation GO:0001707 43 0.029
spinal cord association neuron differentiation GO:0021527 1 0.029
Mouse
negative regulation of gliogenesis GO:0014014 1 0.029
otic vesicle development GO:0071599 42 0.029
regulation of epithelial to mesenchymal transition GO:0010717 3 0.029
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.029
neuron fate determination GO:0048664 2 0.028
compound eye development GO:0048749 2 0.028
Fly
amine metabolic process GO:0009308 2 0.028
dorsal aorta development GO:0035907 4 0.028
negative regulation of multicellular organismal process GO:0051241 69 0.028
protein import GO:0017038 3 0.028
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.028
retinal ganglion cell axon guidance GO:0031290 35 0.028
Zebrafish
post embryonic development GO:0009791 7 0.028
Worm Fly
cell fate specification involved in pattern specification GO:0060573 3 0.027
determination of dorsal identity GO:0048263 13 0.027
eye morphogenesis GO:0048592 144 0.027
Zebrafish
circulatory system process GO:0003013 87 0.027
Zebrafish
single organism membrane fusion GO:0044801 2 0.026
oxoacid metabolic process GO:0043436 31 0.026
regulation of heart contraction GO:0008016 32 0.026
Zebrafish
positive regulation of developmental process GO:0051094 50 0.026
Mouse Worm
ameboidal type cell migration GO:0001667 143 0.026
radial glial cell differentiation GO:0060019 2 0.026
membrane fusion GO:0061025 2 0.026
feeding behavior GO:0007631 5 0.026
regulation of embryonic development GO:0045995 47 0.025
optic placode formation involved in camera type eye formation GO:0046619 3 0.025
regulation of mesenchymal cell proliferation GO:0010464 1 0.025
brain segmentation GO:0035284 6 0.025
axial mesoderm development GO:0048318 10 0.024
regulation of signaling GO:0023051 235 0.024
regulation of protein metabolic process GO:0051246 56 0.024
regulation of endodermal cell fate specification GO:0042663 15 0.024
pronephric glomerulus development GO:0039021 13 0.023
Zebrafish
atrial cardiac muscle cell differentiation GO:0055011 5 0.023
Zebrafish
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.023
positive regulation of neural precursor cell proliferation GO:2000179 1 0.023
Mouse
dorsal aorta morphogenesis GO:0035912 3 0.023
astrocyte differentiation GO:0048708 1 0.022
striated muscle cell differentiation GO:0051146 129 0.022
Zebrafish
dendrite development GO:0016358 9 0.022
response to oxygen containing compound GO:1901700 55 0.022
cell fate commitment involved in pattern specification GO:0060581 6 0.022
negative regulation of signaling GO:0023057 96 0.022
positive regulation of epithelial cell differentiation GO:0030858 2 0.022
posterior lateral line system development GO:0048915 46 0.022
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.022
peptidyl lysine acetylation GO:0018394 2 0.022
regulation of neuron migration GO:2001222 2 0.022
floor plate formation GO:0021508 12 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of cell death GO:0010941 103 0.022
peripheral nervous system neuron axonogenesis GO:0048936 13 0.022
Zebrafish
catabolic process GO:0009056 32 0.022
negative regulation of cell differentiation GO:0045596 46 0.022
circadian rhythm GO:0007623 19 0.021
reproduction GO:0000003 40 0.021
Worm

lhx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.042
disease of anatomical entity DOID:7 0 0.042
eye and adnexa disease DOID:1492 0 0.042
nervous system disease DOID:863 0 0.042
eye disease DOID:5614 0 0.042