Danio rerio

132 known processes

spast

spastin

(Aliases: zgc:85952,MGC85952)

spast biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.107
aging GO:0007568 2 0.107
ubiquitin dependent protein catabolic process GO:0006511 3 0.096
cortical actin cytoskeleton organization GO:0030866 1 0.096
cortical cytoskeleton organization GO:0030865 1 0.093
nitrogen compound metabolic process GO:0006807 319 0.092
Human Fly
macromolecule biosynthetic process GO:0009059 227 0.089
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.089
regulation of gene expression GO:0010468 265 0.085
modification dependent protein catabolic process GO:0019941 3 0.082
larval development GO:0002164 2 0.081
cellular protein catabolic process GO:0044257 4 0.076
establishment of localization GO:0051234 244 0.075
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.074
cellular macromolecule metabolic process GO:0044260 391 0.072
regulation of response to stimulus GO:0048583 269 0.068
muscle structure development GO:0061061 196 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.063
cell projection morphogenesis GO:0048858 244 0.062
positive regulation of cellular component biogenesis GO:0044089 3 0.061
Fly
response to chemical GO:0042221 320 0.061
positive regulation of transport GO:0051050 2 0.060
single organism organelle organization GO:1902589 199 0.058
regulation of macromolecule metabolic process GO:0060255 317 0.056
organic cyclic compound biosynthetic process GO:1901362 223 0.055
regulation of multicellular organism growth GO:0040014 4 0.055
cellular biosynthetic process GO:0044249 286 0.053
cellular component assembly involved in morphogenesis GO:0010927 107 0.053
anterior posterior pattern specification GO:0009952 152 0.053
regulation of metabolic process GO:0019222 359 0.053
regulation of macromolecule biosynthetic process GO:0010556 225 0.052
multicellular organism growth GO:0035264 4 0.052
proteasomal protein catabolic process GO:0010498 2 0.052
compound eye development GO:0048749 2 0.052
peptidyl serine phosphorylation GO:0018105 1 0.051
sensory organ development GO:0007423 393 0.051
cellular amine metabolic process GO:0044106 2 0.051
heterocycle biosynthetic process GO:0018130 215 0.050
stem cell proliferation GO:0072089 4 0.049
cell surface receptor signaling pathway GO:0007166 325 0.049
regulation of binding GO:0051098 3 0.049
single organism localization GO:1902578 225 0.049
Human
specification of symmetry GO:0009799 204 0.048
cellular aromatic compound metabolic process GO:0006725 295 0.048
Human Fly
morphogenesis of an epithelium GO:0002009 333 0.047
striated muscle cell development GO:0055002 108 0.046
regulation of cellular amine metabolic process GO:0033238 0 0.045
regulation of cellular amino acid metabolic process GO:0006521 0 0.045
glycoprotein metabolic process GO:0009100 23 0.045
blood vessel development GO:0001568 246 0.044
synaptic growth at neuromuscular junction GO:0051124 2 0.044
Fly
gene expression GO:0010467 252 0.044
cilium morphogenesis GO:0060271 85 0.043
amine metabolic process GO:0009308 2 0.043
muscle cell development GO:0055001 115 0.042
cellular component assembly GO:0022607 170 0.042
Human Fly
organonitrogen compound metabolic process GO:1901564 74 0.042
Human Fly
purine nucleoside monophosphate catabolic process GO:0009128 4 0.041
Human Fly
head development GO:0060322 303 0.041
oxoacid metabolic process GO:0043436 31 0.041
organelle localization GO:0051640 49 0.040
kupffer s vesicle development GO:0070121 50 0.040
negative regulation of protein phosphorylation GO:0001933 4 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.040
regulation of synapse organization GO:0050807 3 0.040
Fly
regulation of biological quality GO:0065008 263 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.039
hemopoiesis GO:0030097 183 0.038
Fly
oocyte anterior posterior axis specification GO:0007314 4 0.038
meiotic nuclear division GO:0007126 4 0.038
cellular component biogenesis GO:0044085 178 0.038
Human Fly
negative regulation of mitosis GO:0045839 3 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.037
cytokinesis GO:0000910 3 0.037
Human
organelle organization GO:0006996 227 0.037
cellular nitrogen compound metabolic process GO:0034641 290 0.037
Human Fly
chordate embryonic development GO:0043009 271 0.037
cellular ketone metabolic process GO:0042180 11 0.036
cell morphogenesis GO:0000902 289 0.036
determination of bilateral symmetry GO:0009855 204 0.036
regulation of rna metabolic process GO:0051252 224 0.036
immune system process GO:0002376 241 0.036
Fly
cellular component morphogenesis GO:0032989 336 0.036
ribonucleoside monophosphate catabolic process GO:0009158 4 0.036
Human Fly
erythrocyte differentiation GO:0030218 54 0.035
negative regulation of nuclear division GO:0051784 3 0.035
aromatic compound biosynthetic process GO:0019438 217 0.035
maintenance of location GO:0051235 4 0.035
cellular component movement GO:0006928 335 0.035
Fly
regulation of chromosome segregation GO:0051983 1 0.034
brain development GO:0007420 293 0.034
eye development GO:0001654 277 0.034
determination of left right symmetry GO:0007368 179 0.034
phagocytosis GO:0006909 3 0.034
peptidyl serine modification GO:0018209 2 0.034
embryonic organ development GO:0048568 381 0.034
Fly
digestive system development GO:0055123 289 0.034
regulation of protein binding GO:0043393 3 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
mitotic cell cycle embryonic GO:0045448 2 0.033
microtubule based process GO:0007017 60 0.033
digestive tract development GO:0048565 265 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
rna metabolic process GO:0016070 219 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
Human Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
muscle cell differentiation GO:0042692 139 0.032
central nervous system development GO:0007417 387 0.032
regulation of rna biosynthetic process GO:2001141 213 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
neuroblast proliferation GO:0007405 2 0.031
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.031
regionalization GO:0003002 274 0.031
positive regulation of catabolic process GO:0009896 4 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
Human Fly
positive regulation of protein complex assembly GO:0031334 2 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
organic acid metabolic process GO:0006082 31 0.030
organic substance biosynthetic process GO:1901576 289 0.030
meiotic cell cycle process GO:1903046 3 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
digestive tract morphogenesis GO:0048546 231 0.030
chromosome organization GO:0051276 31 0.030
Fly
segmentation GO:0035282 97 0.030
cell part morphogenesis GO:0032990 246 0.030
cytokinetic process GO:0032506 2 0.030
Human
protein metabolic process GO:0019538 183 0.029
determination of heart left right asymmetry GO:0061371 117 0.029
response to carbohydrate GO:0009743 3 0.029
protein dephosphorylation GO:0006470 3 0.029
membrane fusion GO:0061025 2 0.029
regulation of transcription dna templated GO:0006355 213 0.029
regulation of metal ion transport GO:0010959 4 0.029
developmental growth GO:0048589 166 0.029
guanosine containing compound catabolic process GO:1901069 2 0.029
organelle assembly GO:0070925 110 0.029
heart development GO:0007507 313 0.029
locomotion GO:0040011 313 0.028
Fly
regulation of signal transduction GO:0009966 225 0.028
tube morphogenesis GO:0035239 349 0.028
cell projection assembly GO:0030031 64 0.028
heterocycle metabolic process GO:0046483 290 0.028
Human Fly
response to uv GO:0009411 3 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
phagocytosis engulfment GO:0006911 1 0.028
negative regulation of protein kinase activity GO:0006469 4 0.028
protein localization to plasma membrane GO:0072659 1 0.028
adult behavior GO:0030534 2 0.028
single fertilization GO:0007338 3 0.028
regulation of biosynthetic process GO:0009889 250 0.027
cellular response to organic substance GO:0071310 105 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
specification of axis polarity GO:0065001 4 0.027
gastrulation GO:0007369 208 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
regulation of signaling GO:0023051 235 0.027
Fly
rna biosynthetic process GO:0032774 181 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
membrane invagination GO:0010324 1 0.027
vasculature development GO:0001944 278 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
regulation of primary metabolic process GO:0080090 311 0.027
single organism metabolic process GO:0044710 217 0.027
Human Fly
regulation of developmental process GO:0050793 247 0.026
adherens junction organization GO:0034332 4 0.026
cilium organization GO:0044782 71 0.026
regulation of synapse assembly GO:0051963 3 0.026
Fly
regulation of protein catabolic process GO:0042176 1 0.026
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.026
nucleic acid metabolic process GO:0090304 244 0.025
mitochondrion organization GO:0007005 4 0.025
negative regulation of kinase activity GO:0033673 4 0.025
sensory organ morphogenesis GO:0090596 200 0.025
response to transition metal nanoparticle GO:1990267 28 0.025
cell migration GO:0016477 237 0.025
Fly
regulation of mitochondrion organization GO:0010821 1 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
protein acylation GO:0043543 3 0.024
single organism membrane fusion GO:0044801 2 0.024
regulation of cell communication GO:0010646 232 0.024
Fly
cytoskeleton organization GO:0007010 96 0.024
small molecule metabolic process GO:0044281 77 0.024
Human Fly
mitochondrial transport GO:0006839 2 0.024
cell motility GO:0048870 244 0.024
Fly
protein acetylation GO:0006473 2 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
regulation of protein transport GO:0051223 3 0.023
transcription dna templated GO:0006351 181 0.023
muscle organ development GO:0007517 101 0.023
generation of neurons GO:0048699 385 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
axonogenesis GO:0007409 152 0.022
stem cell maintenance GO:0019827 4 0.022
positive regulation of biological process GO:0048518 253 0.022
cytoskeleton dependent cytokinesis GO:0061640 3 0.022
response to stress GO:0006950 263 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
regulation of cell shape GO:0008360 1 0.021
somitogenesis GO:0001756 87 0.021
cell projection organization GO:0030030 284 0.021
striated muscle cell differentiation GO:0051146 129 0.021
response to external stimulus GO:0009605 264 0.021
positive regulation of signal transduction GO:0009967 56 0.021
response to drug GO:0042493 3 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.021
Human Fly
regulation of mrna processing GO:0050684 3 0.021
nuclear import GO:0051170 3 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
response to monosaccharide GO:0034284 3 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
myofibril assembly GO:0030239 48 0.020
response to corticosteroid GO:0031960 1 0.020
cilium assembly GO:0042384 58 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
Human Fly
homeostasis of number of cells GO:0048872 62 0.020
tissue remodeling GO:0048771 4 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
mitotic dna integrity checkpoint GO:0044774 4 0.020
homeostatic process GO:0042592 142 0.020
regulation of cell substrate adhesion GO:0010810 1 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
cell matrix adhesion GO:0007160 4 0.020
transport GO:0006810 220 0.020
Human
gtp metabolic process GO:0046039 4 0.020
regulation of protein complex assembly GO:0043254 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
fertilization GO:0009566 3 0.019
glycoprotein biosynthetic process GO:0009101 21 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
positive regulation of gtpase activity GO:0043547 1 0.019
camera type eye development GO:0043010 222 0.019
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.019
neuron projection morphogenesis GO:0048812 161 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
Fly
biosynthetic process GO:0009058 294 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
macromolecule modification GO:0043412 111 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
axis specification GO:0009798 43 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
cellular component disassembly GO:0022411 1 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
nuclear migration GO:0007097 3 0.019
sequestering of metal ion GO:0051238 3 0.019
sequestering of calcium ion GO:0051208 3 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
blood vessel morphogenesis GO:0048514 216 0.019
neuron differentiation GO:0030182 353 0.018
ion transmembrane transport GO:0034220 91 0.018
protein localization to nucleus GO:0034504 3 0.018
organelle fusion GO:0048284 3 0.018
protein import GO:0017038 3 0.018
convergent extension GO:0060026 118 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
embryonic pattern specification GO:0009880 44 0.018
mitotic g2 dna damage checkpoint GO:0007095 3 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
chemosensory behavior GO:0007635 1 0.018
somite development GO:0061053 96 0.018
heart morphogenesis GO:0003007 156 0.018
regulation of organelle organization GO:0033043 29 0.018
regulation of cell differentiation GO:0045595 142 0.018
phosphorus metabolic process GO:0006793 109 0.018
Human Fly
positive regulation of secretion by cell GO:1903532 1 0.018
single organism transport GO:0044765 206 0.018
Human
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
programmed cell death GO:0012501 119 0.017
negative regulation of biological process GO:0048519 304 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
autophagy GO:0006914 4 0.017
response to glucocorticoid GO:0051384 1 0.017
exocytosis GO:0006887 1 0.017
negative regulation of cellular process GO:0048523 283 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
regulation of cellular response to growth factor stimulus GO:0090287 35 0.017
cellular amide metabolic process GO:0043603 4 0.017
transmembrane transport GO:0055085 120 0.017
cellular protein modification process GO:0006464 100 0.017
nephron epithelium morphogenesis GO:0072088 1 0.017
ion transport GO:0006811 114 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
Human Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
protein targeting to nucleus GO:0044744 3 0.017
cognition GO:0050890 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
nucleic acid templated transcription GO:0097659 181 0.017
golgi vesicle transport GO:0048193 3 0.017
Human
peptidyl lysine acetylation GO:0018394 2 0.016
regulation of axonogenesis GO:0050770 32 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
angiogenesis GO:0001525 158 0.016
localization of cell GO:0051674 244 0.016
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
peptidyl lysine methylation GO:0018022 3 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
embryonic hemopoiesis GO:0035162 53 0.016
Fly
female meiotic division GO:0007143 2 0.016
microtubule based movement GO:0007018 33 0.016
cell substrate adhesion GO:0031589 4 0.016
positive regulation of synapse assembly GO:0051965 1 0.016
Fly
protein modification process GO:0036211 100 0.016
convergent extension involved in gastrulation GO:0060027 71 0.016
negative regulation of signaling GO:0023057 96 0.016
Fly
embryonic heart tube development GO:0035050 133 0.016
sensory perception of touch GO:0050975 2 0.016
negative regulation of cytokine production GO:0001818 1 0.016
regulation of exocytosis GO:0017157 1 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
Fly
cytoplasm organization GO:0007028 4 0.016
oxidative phosphorylation GO:0006119 1 0.016
endosomal transport GO:0016197 2 0.016
immune system development GO:0002520 191 0.016
Fly
myeloid cell differentiation GO:0030099 86 0.016
system process GO:0003008 185 0.016
lamellipodium assembly GO:0030032 1 0.016
positive regulation of signaling GO:0023056 56 0.016
Fly
positive regulation of cell cycle GO:0045787 3 0.016
gtp catabolic process GO:0006184 2 0.016
sulfur compound biosynthetic process GO:0044272 9 0.016
atp catabolic process GO:0006200 4 0.015
Human Fly
muscle tissue development GO:0060537 110 0.015
regulation of cell matrix adhesion GO:0001952 1 0.015
release of sequestered calcium ion into cytosol GO:0051209 3 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
Human Fly
embryonic limb morphogenesis GO:0030326 2 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
striated muscle tissue development GO:0014706 110 0.015
establishment of localization in cell GO:0051649 77 0.015
Human
muscle fiber development GO:0048747 52 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
inner ear development GO:0048839 126 0.015
regulation of cell projection organization GO:0031344 44 0.015
cell cycle GO:0007049 93 0.015
Human Fly
nuclear transport GO:0051169 4 0.015
regulation of cell development GO:0060284 100 0.015
stem cell division GO:0017145 1 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.015
pronuclear migration GO:0035046 1 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
regulation of cellular component organization GO:0051128 86 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
neural tube patterning GO:0021532 33 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
erythrocyte homeostasis GO:0034101 55 0.015
melanin metabolic process GO:0006582 2 0.015
response to organic substance GO:0010033 153 0.014
regulation of localization GO:0032879 104 0.014
skeletal muscle organ development GO:0060538 78 0.014
synaptic vesicle localization GO:0097479 1 0.014
negative regulation of signal transduction GO:0009968 94 0.014
neuron projection development GO:0031175 180 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
single organism cellular localization GO:1902580 46 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
primitive hemopoiesis GO:0060215 27 0.014
regulation of myotube differentiation GO:0010830 2 0.014
positive regulation of ras protein signal transduction GO:0046579 1 0.014
carbohydrate homeostasis GO:0033500 1 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
developmental growth involved in morphogenesis GO:0060560 86 0.014
macromolecular complex disassembly GO:0032984 1 0.014
skeletal muscle tissue development GO:0007519 67 0.014
positive regulation of striated muscle tissue development GO:0045844 1 0.014
mediolateral intercalation GO:0060031 3 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
Fly
secondary metabolic process GO:0019748 3 0.014
regulation of cytokine production GO:0001817 3 0.014
actomyosin structure organization GO:0031032 53 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
negative regulation of catabolic process GO:0009895 3 0.014
cilium movement GO:0003341 26 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.013
neuron development GO:0048666 262 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
axon development GO:0061564 166 0.013
establishment of organelle localization GO:0051656 45 0.013
skeletal system development GO:0001501 181 0.013
cellular response to nutrient levels GO:0031669 2 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
leukocyte homeostasis GO:0001776 2 0.013
metal ion transport GO:0030001 58 0.013
cell substrate junction assembly GO:0007044 2 0.013
response to abiotic stimulus GO:0009628 122 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
heparan sulfate proteoglycan biosynthetic process GO:0015012 5 0.013
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.013
actin filament polymerization GO:0030041 2 0.013
fin regeneration GO:0031101 51 0.013
positive regulation of histone modification GO:0031058 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
liver development GO:0001889 96 0.013
mitotic nuclear division GO:0007067 18 0.013
Fly
regulation of neuron differentiation GO:0045664 56 0.013
mitotic cytokinesis GO:0000281 3 0.013
embryonic digestive tract development GO:0048566 4 0.013
regulation of dna replication GO:0006275 3 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
myeloid cell homeostasis GO:0002262 56 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
renal tubule morphogenesis GO:0061333 1 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
actin cytoskeleton organization GO:0030036 63 0.013
nephron tubule morphogenesis GO:0072078 1 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
negative regulation of defense response GO:0031348 2 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.013
regulation of canonical wnt signaling pathway GO:0060828 34 0.013
hormone secretion GO:0046879 2 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
otolith development GO:0048840 32 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
lamellipodium organization GO:0097581 1 0.012
ear development GO:0043583 127 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
spindle localization GO:0051653 12 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
positive regulation of reproductive process GO:2000243 2 0.012
death GO:0016265 121 0.012
negative regulation of metabolic process GO:0009892 86 0.012
glucose homeostasis GO:0042593 1 0.012
otic vesicle morphogenesis GO:0071600 34 0.012
alcohol biosynthetic process GO:0046165 2 0.012
establishment or maintenance of cell polarity GO:0007163 29 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
neuron projection guidance GO:0097485 86 0.012
hormone transport GO:0009914 2 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
wnt signaling pathway GO:0016055 80 0.012
cell aging GO:0007569 2 0.012
cellular localization GO:0051641 97 0.012
Human
negative regulation of biosynthetic process GO:0009890 55 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
protein polymerization GO:0051258 4 0.012
growth GO:0040007 174 0.012
regulation of transport GO:0051049 45 0.012
nephron morphogenesis GO:0072028 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
extracellular matrix assembly GO:0085029 1 0.012
negative regulation of catalytic activity GO:0043086 21 0.012
heart looping GO:0001947 94 0.012
hindbrain development GO:0030902 91 0.012
regulation of anterior head development GO:2000742 2 0.012
phosphorylation GO:0016310 69 0.012
rna modification GO:0009451 2 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.012
regulation of erythrocyte differentiation GO:0045646 2 0.011
regulation of growth rate GO:0040009 1 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
histone h3 k4 methylation GO:0051568 2 0.011
regulation of cell death GO:0010941 103 0.011
cellular response to radiation GO:0071478 4 0.011
cellular response to external stimulus GO:0071496 2 0.011
neurotransmitter transport GO:0006836 2 0.011
developmental programmed cell death GO:0010623 4 0.011
histone phosphorylation GO:0016572 2 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
organic substance transport GO:0071702 58 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
positive regulation of chromatin modification GO:1903310 1 0.011

spast disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.017
Human
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.013
Human
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013