Danio rerio

14 known processes

aldh2b

aldehyde dehydrogenase 2b

(Aliases: zgc:85659,aldh2l,wu:fi26c02,cb154,aldh2)

aldh2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular aromatic compound metabolic process GO:0006725 295 0.213
Yeast
single organism biosynthetic process GO:0044711 71 0.148
Yeast
cell projection morphogenesis GO:0048858 244 0.144
eye development GO:0001654 277 0.135
Zebrafish
small molecule metabolic process GO:0044281 77 0.132
Yeast Zebrafish
aging GO:0007568 2 0.128
nitrogen compound metabolic process GO:0006807 319 0.112
Yeast
nucleoside phosphate metabolic process GO:0006753 28 0.111
Yeast
response to wounding GO:0009611 116 0.106
Zebrafish
signal transduction GO:0007165 455 0.106
Zebrafish
apoptotic process GO:0006915 116 0.100
Rat
regulation of multicellular organism growth GO:0040014 4 0.099
negative regulation of signal transduction GO:0009968 94 0.099
multicellular organism growth GO:0035264 4 0.093
pigmentation GO:0043473 85 0.093
response to chemical GO:0042221 320 0.092
cellular amino acid metabolic process GO:0006520 7 0.091
Yeast
maintenance of location GO:0051235 4 0.091
Worm
negative regulation of biological process GO:0048519 304 0.087
Rat
immune system process GO:0002376 241 0.086
adult behavior GO:0030534 2 0.083
single organism metabolic process GO:0044710 217 0.082
Human Yeast Zebrafish Rat
locomotion GO:0040011 313 0.082
establishment of protein localization to organelle GO:0072594 4 0.078
regulation of cell communication GO:0010646 232 0.078
retina development in camera type eye GO:0060041 146 0.076
positive regulation of catabolic process GO:0009896 4 0.074
autophagy GO:0006914 4 0.073
cellular amino acid biosynthetic process GO:0008652 2 0.071
Yeast
heterocycle metabolic process GO:0046483 290 0.071
Yeast
gtp catabolic process GO:0006184 2 0.070
response to amino acid GO:0043200 2 0.068
nucleobase containing small molecule metabolic process GO:0055086 32 0.067
Yeast
oxoacid metabolic process GO:0043436 31 0.066
Yeast
negative regulation of cellular process GO:0048523 283 0.059
Rat
oxidation reduction process GO:0055114 41 0.055
Human Yeast Rat
regulation of biological quality GO:0065008 263 0.054
Zebrafish Worm
cellular modified amino acid metabolic process GO:0006575 3 0.053
cellular ketone metabolic process GO:0042180 11 0.053
regulation of primary metabolic process GO:0080090 311 0.053
biosynthetic process GO:0009058 294 0.053
Yeast
nucleobase containing compound metabolic process GO:0006139 274 0.051
Yeast
response to nitrogen compound GO:1901698 19 0.051
Rat
organic cyclic compound metabolic process GO:1901360 301 0.051
Yeast
regulation of signal transduction GO:0009966 225 0.050
phosphate containing compound metabolic process GO:0006796 108 0.049
Yeast
toxin transport GO:1901998 2 0.049
transmembrane transport GO:0055085 120 0.048
camera type eye development GO:0043010 222 0.048
Zebrafish
response to vitamin b3 GO:0033552 2 0.046
organic acid metabolic process GO:0006082 31 0.046
Yeast
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.046
amine metabolic process GO:0009308 2 0.046
Yeast
positive regulation of cellular catabolic process GO:0031331 3 0.045
response to copper ion GO:0046688 13 0.045
hindbrain morphogenesis GO:0021575 22 0.044
Zebrafish
cell migration GO:0016477 237 0.044
neuron development GO:0048666 262 0.044
response to endogenous stimulus GO:0009719 83 0.044
Rat
positive regulation of secretion by cell GO:1903532 1 0.044
cellular response to organic substance GO:0071310 105 0.043
Rat
neuron differentiation GO:0030182 353 0.043
negative regulation of cellular catabolic process GO:0031330 3 0.043
blood vessel development GO:0001568 246 0.043
cellular amine metabolic process GO:0044106 2 0.042
Yeast
response to organic substance GO:0010033 153 0.042
Rat
leukocyte proliferation GO:0070661 1 0.042
programmed cell death GO:0012501 119 0.042
Rat
water homeostasis GO:0030104 4 0.042
response to nutrient GO:0007584 3 0.042
multicellular organismal signaling GO:0035637 22 0.042
Zebrafish
response to external stimulus GO:0009605 264 0.041
Rat
regulation of signaling GO:0023051 235 0.040
guanosine containing compound metabolic process GO:1901068 4 0.040
negative regulation of catabolic process GO:0009895 3 0.040
regeneration GO:0031099 91 0.040
Zebrafish
pancreas development GO:0031016 84 0.040
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.039
Yeast
response to drug GO:0042493 3 0.039
lipid storage GO:0019915 1 0.038
Worm
organonitrogen compound metabolic process GO:1901564 74 0.038
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
generation of neurons GO:0048699 385 0.038
lipid metabolic process GO:0006629 52 0.037
Zebrafish
mononuclear cell proliferation GO:0032943 1 0.037
appendage development GO:0048736 80 0.037
Zebrafish
axon development GO:0061564 166 0.037
purine nucleotide metabolic process GO:0006163 27 0.037
synaptic growth at neuromuscular junction GO:0051124 2 0.036
determination of left right symmetry GO:0007368 179 0.035
Zebrafish
sensory organ development GO:0007423 393 0.035
Zebrafish
response to vitamin GO:0033273 3 0.035
cellular response to prostaglandin stimulus GO:0071379 3 0.034
ribonucleotide metabolic process GO:0009259 27 0.033
larval development GO:0002164 2 0.033
transcription from rna polymerase ii promoter GO:0006366 80 0.033
purine ribonucleotide metabolic process GO:0009150 27 0.032
positive regulation of secretion GO:0051047 1 0.032
organic substance transport GO:0071702 58 0.032
protein localization to nucleus GO:0034504 3 0.031
cellular response to nutrient levels GO:0031669 2 0.031
negative regulation of tor signaling GO:0032007 2 0.031
regulation of protein transport GO:0051223 3 0.031
heart development GO:0007507 313 0.031
establishment of localization GO:0051234 244 0.030
response to oxygen levels GO:0070482 25 0.030
Rat
lymphocyte proliferation GO:0046651 1 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
lipid catabolic process GO:0016042 4 0.028
carbohydrate derivative metabolic process GO:1901135 61 0.028
regulation of protein catabolic process GO:0042176 1 0.028
protein import into nucleus GO:0006606 3 0.028
regulation of cytokine production GO:0001817 3 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.027
gtp metabolic process GO:0046039 4 0.027
organic substance biosynthetic process GO:1901576 289 0.026
Yeast
regulation of cell activation GO:0050865 1 0.026
response to oxygen containing compound GO:1901700 55 0.026
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
immune response GO:0006955 28 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
electron transport chain GO:0022900 2 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
Yeast
protein localization GO:0008104 40 0.024
regulation of cellular component organization GO:0051128 86 0.024
superoxide metabolic process GO:0006801 2 0.023
regulation of dna replication GO:0006275 3 0.023
nucleoside metabolic process GO:0009116 11 0.023
response to stress GO:0006950 263 0.023
Yeast Zebrafish Rat
neuronal action potential GO:0019228 18 0.023
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.023
anion transport GO:0006820 38 0.023
organophosphate metabolic process GO:0019637 37 0.023
Yeast
regulation of membrane potential GO:0042391 23 0.022
Zebrafish
regulation of inflammatory response GO:0050727 2 0.022
system process GO:0003008 185 0.022
Zebrafish
positive regulation of transport GO:0051050 2 0.022
phosphorus metabolic process GO:0006793 109 0.022
Yeast
cell part morphogenesis GO:0032990 246 0.022
single organism nuclear import GO:1902593 3 0.022
phagocytosis GO:0006909 3 0.022
regulation of intracellular protein transport GO:0033157 3 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
negative regulation of hormone secretion GO:0046888 2 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
response to biotic stimulus GO:0009607 97 0.021
Rat
negative regulation of programmed cell death GO:0043069 58 0.021
Rat
single organism behavior GO:0044708 24 0.021
action potential GO:0001508 19 0.021
Zebrafish
cellular response to extracellular stimulus GO:0031668 2 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.020
protein targeting to nucleus GO:0044744 3 0.020
cell growth GO:0016049 57 0.020
neurological system process GO:0050877 62 0.020
Zebrafish
regulation of gene expression GO:0010468 265 0.020
digestive system development GO:0055123 289 0.020
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.020
tissue remodeling GO:0048771 4 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
regulation of gtpase activity GO:0043087 2 0.019
positive regulation of cell activation GO:0050867 1 0.019
negative regulation of epithelial cell proliferation GO:0050680 1 0.019
nuclear import GO:0051170 3 0.019
chloride transmembrane transport GO:1902476 4 0.019
growth GO:0040007 174 0.019
Zebrafish
cellular aldehyde metabolic process GO:0006081 4 0.019
gland development GO:0048732 143 0.019
Zebrafish Rat
protein secretion GO:0009306 1 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
negative regulation of nucleotide metabolic process GO:0045980 7 0.019
meiotic nuclear division GO:0007126 4 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
establishment of localization in cell GO:0051649 77 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
rna biosynthetic process GO:0032774 181 0.018
behavior GO:0007610 74 0.018
epithelial cell differentiation GO:0030855 116 0.018
negative regulation of signaling GO:0023057 96 0.018
ribose phosphate metabolic process GO:0019693 27 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of autophagy GO:0010506 3 0.018
response to inorganic substance GO:0010035 38 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
photoreceptor cell differentiation GO:0046530 55 0.018
negative regulation of neural precursor cell proliferation GO:2000178 1 0.018
axon ensheathment GO:0008366 18 0.018
Zebrafish
hemopoiesis GO:0030097 183 0.018
regulation of protein metabolic process GO:0051246 56 0.017
regulation of hormone secretion GO:0046883 2 0.017
regulation of apoptotic process GO:0042981 98 0.017
Rat
fin regeneration GO:0031101 51 0.017
Zebrafish
cellular response to endogenous stimulus GO:0071495 68 0.017
Rat
regulation of metabolic process GO:0019222 359 0.017
vasculature development GO:0001944 278 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
cellular hormone metabolic process GO:0034754 19 0.017
Zebrafish
somatic muscle development GO:0007525 4 0.017
protein acetylation GO:0006473 2 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
nucleic acid metabolic process GO:0090304 244 0.017
inorganic anion transport GO:0015698 25 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
protein stabilization GO:0050821 2 0.017
regulation of blood vessel size GO:0050880 2 0.017
positive regulation of cellular process GO:0048522 201 0.016
protein acylation GO:0043543 3 0.016
myelination GO:0042552 18 0.016
Zebrafish
lipid biosynthetic process GO:0008610 22 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
cellular catabolic process GO:0044248 27 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
epidermis development GO:0008544 48 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
blood vessel morphogenesis GO:0048514 216 0.016
protein import GO:0017038 3 0.016
stem cell division GO:0017145 1 0.016
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.016
negative regulation of dna replication GO:0008156 2 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
axon ensheathment in central nervous system GO:0032291 2 0.015
Zebrafish
negative regulation of protein kinase activity GO:0006469 4 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
double strand break repair GO:0006302 3 0.015
stem cell proliferation GO:0072089 4 0.015
pigment cell differentiation GO:0050931 38 0.015
intracellular receptor signaling pathway GO:0030522 30 0.015
Zebrafish
negative regulation of cell communication GO:0010648 96 0.015
cellular localization GO:0051641 97 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
nucleotide metabolic process GO:0009117 28 0.015
Yeast
fatty acid transport GO:0015908 1 0.015
response to fatty acid GO:0070542 5 0.015
Rat
retina morphogenesis in camera type eye GO:0060042 79 0.015
cell motility GO:0048870 244 0.015
regulation of hormone levels GO:0010817 21 0.015
Zebrafish
tor signaling GO:0031929 7 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
bicarbonate transport GO:0015701 4 0.014
chemotaxis GO:0006935 104 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
cell death GO:0008219 121 0.014
Rat
negative regulation of cell death GO:0060548 60 0.014
Rat
organophosphate biosynthetic process GO:0090407 23 0.014
regulation of protein modification process GO:0031399 29 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
negative regulation of gene expression GO:0010629 65 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
positive regulation of cell division GO:0051781 2 0.014
negative regulation of apoptotic signaling pathway GO:2001234 10 0.014
transcription dna templated GO:0006351 181 0.014
cell morphogenesis GO:0000902 289 0.014
developmental growth GO:0048589 166 0.014
Zebrafish
cellular respiration GO:0045333 3 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
negative regulation of defense response GO:0031348 2 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
stem cell maintenance GO:0019827 4 0.014
respiratory electron transport chain GO:0022904 2 0.014
ensheathment of neurons GO:0007272 18 0.014
Zebrafish
ion transmembrane transport GO:0034220 91 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
response to external biotic stimulus GO:0043207 97 0.014
Rat
chordate embryonic development GO:0043009 271 0.013
Zebrafish
dicarboxylic acid metabolic process GO:0043648 1 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
long chain fatty acid transport GO:0015909 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
tube morphogenesis GO:0035239 349 0.013
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.013
positive regulation of biological process GO:0048518 253 0.013
cellular response to radiation GO:0071478 4 0.013
neuron projection development GO:0031175 180 0.013
ear development GO:0043583 127 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
cell proliferation GO:0008283 80 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
cation transport GO:0006812 81 0.013
purine nucleotide biosynthetic process GO:0006164 20 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
organic acid catabolic process GO:0016054 3 0.013
androgen metabolic process GO:0008209 2 0.013
carboxylic acid biosynthetic process GO:0046394 12 0.013
Yeast
regulation of intracellular signal transduction GO:1902531 57 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
protein localization to vacuole GO:0072665 1 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of cytoplasmic transport GO:1903649 4 0.012
tissue regeneration GO:0042246 74 0.012
Zebrafish
regulation of catalytic activity GO:0050790 55 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
Rat
embryonic skeletal system morphogenesis GO:0048704 93 0.012
Zebrafish
nucleoside monophosphate catabolic process GO:0009125 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
cellular biosynthetic process GO:0044249 286 0.012
Yeast
regulation of phosphate metabolic process GO:0019220 43 0.012
response to carbohydrate GO:0009743 3 0.012
digestive tract development GO:0048565 265 0.012
Zebrafish
regulation of cellular protein catabolic process GO:1903362 1 0.012
regulation of tube size GO:0035150 2 0.012
small molecule biosynthetic process GO:0044283 16 0.012
Yeast
neuroblast proliferation GO:0007405 2 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
response to acid chemical GO:0001101 17 0.012
Rat
response to other organism GO:0051707 97 0.012
Rat
carboxylic acid catabolic process GO:0046395 3 0.012
localization of cell GO:0051674 244 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
response to abiotic stimulus GO:0009628 122 0.012
Yeast Rat
macromolecule biosynthetic process GO:0009059 227 0.011
small molecule catabolic process GO:0044282 3 0.011
positive regulation of cell cycle GO:0045787 3 0.011
nuclear transport GO:0051169 4 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
glucose homeostasis GO:0042593 1 0.011
cellular component disassembly GO:0022411 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
intracellular signal transduction GO:0035556 85 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
Zebrafish
axonogenesis GO:0007409 152 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
response to prostaglandin GO:0034694 5 0.011
hormone transport GO:0009914 2 0.011
macromolecule modification GO:0043412 111 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
organ regeneration GO:0031100 1 0.011
regulation of biosynthetic process GO:0009889 250 0.011
neural crest cell development GO:0014032 62 0.011
response to organonitrogen compound GO:0010243 12 0.011
Rat
transmission of nerve impulse GO:0019226 19 0.011
Zebrafish
immune system development GO:0002520 191 0.011
single organism localization GO:1902578 225 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
cellular response to stress GO:0033554 62 0.011
retinoid metabolic process GO:0001523 15 0.010
Zebrafish
positive regulation of dna metabolic process GO:0051054 1 0.010
intrinsic apoptotic signaling pathway GO:0097193 20 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
ameboidal type cell migration GO:0001667 143 0.010
macromolecule localization GO:0033036 54 0.010
Worm
internal peptidyl lysine acetylation GO:0018393 2 0.010
response to bacterium GO:0009617 58 0.010
Rat
regulation of cell cycle GO:0051726 52 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
regulation of cell migration GO:0030334 40 0.010
glycosyl compound metabolic process GO:1901657 11 0.010
regulation of response to stimulus GO:0048583 269 0.010
single organism transport GO:0044765 206 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
chemosensory behavior GO:0007635 1 0.010
homeostatic process GO:0042592 142 0.010
Worm
negative regulation of protein phosphorylation GO:0001933 4 0.010
death GO:0016265 121 0.010
Rat

aldh2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.011