Danio rerio

0 known processes

uncx4.1

Unc4.1 homeobox (C. elegans)

(Aliases: uncx)

uncx4.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular aromatic compound metabolic process GO:0006725 295 0.277
Worm
aromatic compound biosynthetic process GO:0019438 217 0.231
Worm
cellular biosynthetic process GO:0044249 286 0.221
Worm
rna biosynthetic process GO:0032774 181 0.212
Worm
biosynthetic process GO:0009058 294 0.198
Worm
regulation of biosynthetic process GO:0009889 250 0.193
Worm
cellular macromolecule metabolic process GO:0044260 391 0.186
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.176
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.173
Worm
nitrogen compound metabolic process GO:0006807 319 0.157
Worm
regulation of rna metabolic process GO:0051252 224 0.149
Worm
regulation of metabolic process GO:0019222 359 0.146
Mouse Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.132
Worm
transcription dna templated GO:0006351 181 0.124
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.123
Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.115
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.114
Worm
cell surface receptor signaling pathway GO:0007166 325 0.113
brain development GO:0007420 293 0.112
Mouse
signal transduction GO:0007165 455 0.112
regulation of primary metabolic process GO:0080090 311 0.108
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.108
Worm
organic cyclic compound metabolic process GO:1901360 301 0.108
Worm
macromolecule biosynthetic process GO:0009059 227 0.106
Worm
somite development GO:0061053 96 0.105
nucleic acid metabolic process GO:0090304 244 0.099
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.098
Worm
regulation of transcription dna templated GO:0006355 213 0.096
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.094
Worm
gene expression GO:0010467 252 0.091
Mouse Worm
heart development GO:0007507 313 0.090
regulation of macromolecule metabolic process GO:0060255 317 0.088
Mouse Worm
rna metabolic process GO:0016070 219 0.087
Worm
heterocycle biosynthetic process GO:0018130 215 0.082
Worm
muscle cell development GO:0055001 115 0.081
cellular macromolecule biosynthetic process GO:0034645 224 0.078
Worm
larval development GO:0002164 2 0.076
regulation of biological quality GO:0065008 263 0.074
regulation of developmental process GO:0050793 247 0.074
Mouse
chordate embryonic development GO:0043009 271 0.072
regulation of rna biosynthetic process GO:2001141 213 0.072
Worm
negative regulation of biological process GO:0048519 304 0.071
organic substance biosynthetic process GO:1901576 289 0.070
Worm
regulation of multicellular organismal process GO:0051239 277 0.070
Worm
nucleic acid templated transcription GO:0097659 181 0.068
Worm
regulation of multicellular organismal development GO:2000026 223 0.067
regionalization GO:0003002 274 0.067
mesenchyme development GO:0060485 127 0.065
locomotion GO:0040011 313 0.065
head development GO:0060322 303 0.065
Mouse
regulation of response to stimulus GO:0048583 269 0.064
muscle structure development GO:0061061 196 0.063
regulation of reproductive process GO:2000241 4 0.063
specification of symmetry GO:0009799 204 0.062
regulation of gene expression GO:0010468 265 0.060
Mouse Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.060
embryo development ending in birth or egg hatching GO:0009792 271 0.058
somitogenesis GO:0001756 87 0.057
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.056
heterocycle metabolic process GO:0046483 290 0.054
Worm
amine metabolic process GO:0009308 2 0.054
central nervous system development GO:0007417 387 0.053
Mouse
muscle organ development GO:0007517 101 0.053
cartilage development GO:0051216 96 0.052
Mouse
striated muscle cell development GO:0055002 108 0.051
cellular amine metabolic process GO:0044106 2 0.050
morphogenesis of an epithelium GO:0002009 333 0.050
muscle cell differentiation GO:0042692 139 0.050
bmp signaling pathway GO:0030509 52 0.050
regulation of cellular metabolic process GO:0031323 320 0.049
Worm
striated muscle tissue development GO:0014706 110 0.048
regulation of nucleic acid templated transcription GO:1903506 213 0.048
Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.047
regulation of cellular ketone metabolic process GO:0010565 7 0.046
cellular component morphogenesis GO:0032989 336 0.045
regulation of cellular amine metabolic process GO:0033238 0 0.044
skeletal muscle organ development GO:0060538 78 0.044
regulation of bmp signaling pathway GO:0030510 39 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
skeletal system development GO:0001501 181 0.044
Mouse
tube morphogenesis GO:0035239 349 0.043
maintenance of location GO:0051235 4 0.042
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.041
Worm
anterior posterior pattern specification GO:0009952 152 0.040
retina development in camera type eye GO:0060041 146 0.040
segmentation GO:0035282 97 0.039
cell morphogenesis GO:0000902 289 0.039
skeletal system morphogenesis GO:0048705 102 0.038
Mouse
neuron development GO:0048666 262 0.038
embryonic skeletal system development GO:0048706 97 0.035
small molecule metabolic process GO:0044281 77 0.035
regulation of stem cell differentiation GO:2000736 4 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
regulation of mrna processing GO:0050684 3 0.034
single organism metabolic process GO:0044710 217 0.034
gastrulation GO:0007369 208 0.034
cardiac chamber development GO:0003205 19 0.034
protein metabolic process GO:0019538 183 0.033
cellular ketone metabolic process GO:0042180 11 0.033
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.033
regulation of signaling GO:0023051 235 0.033
digestive tract morphogenesis GO:0048546 231 0.033
determination of left right symmetry GO:0007368 179 0.032
cellular component movement GO:0006928 335 0.032
muscle tissue development GO:0060537 110 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.031
stem cell differentiation GO:0048863 117 0.030
response to chemical GO:0042221 320 0.030
cognition GO:0050890 1 0.030
heart morphogenesis GO:0003007 156 0.030
aging GO:0007568 2 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
neuron differentiation GO:0030182 353 0.029
Mouse
immune system development GO:0002520 191 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
stem cell development GO:0048864 82 0.029
oocyte maturation GO:0001556 4 0.029
digestive tract development GO:0048565 265 0.029
regulation of cell differentiation GO:0045595 142 0.029
Mouse
somite specification GO:0001757 12 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
cellular protein metabolic process GO:0044267 129 0.028
central nervous system myelination GO:0022010 2 0.028
post embryonic organ development GO:0048569 4 0.028
epidermal cell fate specification GO:0009957 4 0.027
embryonic organ development GO:0048568 381 0.027
regulation of cell development GO:0060284 100 0.027
oxoacid metabolic process GO:0043436 31 0.027
determination of bilateral symmetry GO:0009855 204 0.027
post anal tail morphogenesis GO:0036342 19 0.027
positive regulation of biological process GO:0048518 253 0.026
Worm
cell projection morphogenesis GO:0048858 244 0.026
localization of cell GO:0051674 244 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
heart looping GO:0001947 94 0.026
axon ensheathment in central nervous system GO:0032291 2 0.026
cellular component assembly involved in morphogenesis GO:0010927 107 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.025
connective tissue development GO:0061448 99 0.025
Mouse
ectodermal placode development GO:0071696 37 0.025
negative regulation of cellular process GO:0048523 283 0.024
regulation of mrna splicing via spliceosome GO:0048024 3 0.024
negative regulation of gene expression GO:0010629 65 0.024
dorsal ventral pattern formation GO:0009953 125 0.023
neuroblast proliferation GO:0007405 2 0.023
apoptotic process involved in development GO:1902742 2 0.023
endoderm formation GO:0001706 29 0.023
positive regulation of blood circulation GO:1903524 2 0.023
gland development GO:0048732 143 0.023
positive regulation of cell cycle GO:0045787 3 0.023
cell projection organization GO:0030030 284 0.023
sensory organ development GO:0007423 393 0.023
olfactory lobe development GO:0021988 4 0.023
Mouse
hemopoiesis GO:0030097 183 0.023
phagocytosis GO:0006909 3 0.023
response to stress GO:0006950 263 0.023
digestive system development GO:0055123 289 0.023
negative regulation of signal transduction GO:0009968 94 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.023
neuron projection morphogenesis GO:0048812 161 0.022
positive regulation of biosynthetic process GO:0009891 68 0.022
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.022
single organism organelle organization GO:1902589 199 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
somatic muscle development GO:0007525 4 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
regulation of signal transduction GO:0009966 225 0.021
stem cell maintenance GO:0019827 4 0.021
enzyme linked receptor protein signaling pathway GO:0007167 106 0.021
developmental growth GO:0048589 166 0.021
transmission of nerve impulse GO:0019226 19 0.021
system process GO:0003008 185 0.021
Worm
carbohydrate biosynthetic process GO:0016051 1 0.021
developmental programmed cell death GO:0010623 4 0.021
immune system process GO:0002376 241 0.021
negative regulation of response to stimulus GO:0048585 104 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.021
tissue remodeling GO:0048771 4 0.021
phosphatidylinositol mediated signaling GO:0048015 2 0.020
striated muscle cell differentiation GO:0051146 129 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
pronephros development GO:0048793 69 0.020
cell migration GO:0016477 237 0.020
skeletal muscle tissue development GO:0007519 67 0.020
ear development GO:0043583 127 0.020
muscle fiber development GO:0048747 52 0.020
mesenchymal cell differentiation GO:0048762 87 0.020
embryonic heart tube morphogenesis GO:0003143 108 0.020
organic acid metabolic process GO:0006082 31 0.020
lymph vessel development GO:0001945 27 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
embryonic cranial skeleton morphogenesis GO:0048701 90 0.019
branchiomotor neuron axon guidance GO:0021785 1 0.019
cellular component biogenesis GO:0044085 178 0.019
camera type eye development GO:0043010 222 0.019
stem cell proliferation GO:0072089 4 0.019
negative regulation of map kinase activity GO:0043407 2 0.019
regulation of organ growth GO:0046620 3 0.019
regulation of synapse assembly GO:0051963 3 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
negative regulation of kinase activity GO:0033673 4 0.019
cell motility GO:0048870 244 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.019
growth GO:0040007 174 0.019
negative regulation of developmental process GO:0051093 65 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
negative regulation of cell communication GO:0010648 96 0.019
retina morphogenesis in camera type eye GO:0060042 79 0.019
regulation of cytokine production GO:0001817 3 0.018
endoderm development GO:0007492 49 0.018
regulation of cell shape GO:0008360 1 0.018
organelle assembly GO:0070925 110 0.018
regulation of dendrite development GO:0050773 3 0.018
compound eye development GO:0048749 2 0.018
urogenital system development GO:0001655 97 0.018
circulatory system process GO:0003013 87 0.018
cellular response to organic substance GO:0071310 105 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
regulation of stem cell proliferation GO:0072091 2 0.017
vasculature development GO:0001944 278 0.017
generation of neurons GO:0048699 385 0.017
Mouse
nephron tubule morphogenesis GO:0072078 1 0.017
renal tubule morphogenesis GO:0061333 1 0.017
multicellular organism growth GO:0035264 4 0.017
adult behavior GO:0030534 2 0.017
cell part morphogenesis GO:0032990 246 0.017
female gonad development GO:0008585 4 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
cranial nerve development GO:0021545 42 0.017
positive regulation of gene expression GO:0010628 71 0.017
negative regulation of metabolic process GO:0009892 86 0.017
myofibril assembly GO:0030239 48 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
cranial ganglion development GO:0061550 3 0.016
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
axon development GO:0061564 166 0.016
regulation of binding GO:0051098 3 0.016
regulation of cell activation GO:0050865 1 0.016
regulation of oocyte development GO:0060281 3 0.016
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.016
olfactory bulb development GO:0021772 4 0.016
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
myotube cell development GO:0014904 35 0.016
adherens junction organization GO:0034332 4 0.016
neuronal action potential GO:0019228 18 0.016
negative regulation of chemotaxis GO:0050922 4 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
negative regulation of stem cell differentiation GO:2000737 2 0.015
positive regulation of striated muscle cell differentiation GO:0051155 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
notochord development GO:0030903 54 0.015
leukocyte proliferation GO:0070661 1 0.015
positive regulation of transport GO:0051050 2 0.015
Worm
protein dephosphorylation GO:0006470 3 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
single organism localization GO:1902578 225 0.015
Worm
hindbrain development GO:0030902 91 0.015
regulation of muscle contraction GO:0006937 3 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
skeletal muscle fiber development GO:0048741 35 0.015
histone h3 k4 methylation GO:0051568 2 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
regulation of jak stat cascade GO:0046425 3 0.015
alcohol biosynthetic process GO:0046165 2 0.015
lipid storage GO:0019915 1 0.015
regulation of cellular component organization GO:0051128 86 0.014
eye morphogenesis GO:0048592 144 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
behavior GO:0007610 74 0.014
astrocyte differentiation GO:0048708 1 0.014
response to external stimulus GO:0009605 264 0.014
nephron morphogenesis GO:0072028 2 0.014
negative regulation of activin receptor signaling pathway GO:0032926 5 0.014
renal system development GO:0072001 94 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.014
female sex differentiation GO:0046660 4 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
cytokinesis GO:0000910 3 0.014
positive regulation of metabolic process GO:0009893 108 0.014
gastrulation with mouth forming second GO:0001702 44 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
regulation of inflammatory response GO:0050727 2 0.014
negative regulation of reproductive process GO:2000242 3 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.013
cellular component assembly GO:0022607 170 0.013
regulation of cell projection assembly GO:0060491 4 0.013
hematopoietic progenitor cell differentiation GO:0002244 23 0.013
positive regulation of cell communication GO:0010647 56 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
single organism transport GO:0044765 206 0.013
Worm
neuron fate determination GO:0048664 2 0.013
cardiac ventricle development GO:0003231 9 0.013
cardiac atrium development GO:0003230 4 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
cell proliferation GO:0008283 80 0.013
Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.013
positive regulation of cellular process GO:0048522 201 0.013
single organism nuclear import GO:1902593 3 0.013
kidney development GO:0001822 92 0.013
atp catabolic process GO:0006200 4 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
tyrosine phosphorylation of stat protein GO:0007260 1 0.012
activin receptor signaling pathway GO:0032924 8 0.012
action potential GO:0001508 19 0.012
establishment of localization GO:0051234 244 0.012
Worm
regulation of activin receptor signaling pathway GO:0032925 5 0.012
response to organic substance GO:0010033 153 0.012
regulation of protein complex assembly GO:0043254 3 0.012
mesoderm development GO:0007498 88 0.012
regulation of ph GO:0006885 3 0.012
actin filament based movement GO:0030048 1 0.012
biological adhesion GO:0022610 40 0.012
negative regulation of cytokine production GO:0001818 1 0.012
regulation of nervous system development GO:0051960 90 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
response to wounding GO:0009611 116 0.012
regulation of filopodium assembly GO:0051489 2 0.012
smooth muscle contraction GO:0006939 2 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
regulation of heart growth GO:0060420 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
response to carbohydrate GO:0009743 3 0.012
cellular component disassembly GO:0022411 1 0.012
nuclear transport GO:0051169 4 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of neuron differentiation GO:0045664 56 0.012
auditory receptor cell fate commitment GO:0009912 4 0.012
eye development GO:0001654 277 0.012
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
protein homooligomerization GO:0051260 3 0.011
regulation of blood vessel size GO:0050880 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
embryonic heart tube development GO:0035050 133 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
auditory receptor cell fate determination GO:0042668 2 0.011
positive regulation of histone modification GO:0031058 1 0.011
mitochondrion organization GO:0007005 4 0.011
positive regulation of cell differentiation GO:0045597 30 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
axon guidance GO:0007411 86 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
positive regulation of jak stat cascade GO:0046427 2 0.011
small molecule catabolic process GO:0044282 3 0.011
regulation of cell communication GO:0010646 232 0.011
nerve development GO:0021675 45 0.011
mesenchymal cell development GO:0014031 78 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
axonogenesis GO:0007409 152 0.011
homeostatic process GO:0042592 142 0.011
response to hexose GO:0009746 3 0.011
regulation of tube size GO:0035150 2 0.011
organelle organization GO:0006996 227 0.011
cellular protein catabolic process GO:0044257 4 0.011
cardiac muscle fiber development GO:0048739 3 0.011
positive regulation of catabolic process GO:0009896 4 0.011
septum transversum development GO:0003343 4 0.011
blood circulation GO:0008015 87 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
negative regulation of signaling GO:0023057 96 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
convergent extension GO:0060026 118 0.011
centrosome organization GO:0051297 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
membrane fusion GO:0061025 2 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
smoothened signaling pathway GO:0007224 30 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
protein stabilization GO:0050821 2 0.010
negative regulation of defense response GO:0031348 2 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
positive regulation of muscle tissue development GO:1901863 1 0.010
response to vitamin GO:0033273 3 0.010
heart contraction GO:0060047 71 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
regulation of wound healing GO:0061041 2 0.010
chondrocyte development GO:0002063 4 0.010
negative regulation of gliogenesis GO:0014014 1 0.010
regulation of localization GO:0032879 104 0.010
Worm
facial nerve morphogenesis GO:0021610 1 0.010
facial nerve development GO:0021561 3 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
mitotic cell cycle GO:0000278 64 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
myeloid cell development GO:0061515 32 0.010

uncx4.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
nervous system disease DOID:863 0 0.020
eye disease DOID:5614 0 0.020
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.017
musculoskeletal system disease DOID:17 0 0.016
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
myopathy DOID:423 0 0.011