Danio rerio

0 known processes

themis

thymocyte selection associated

(Aliases: im:7138580,tsepa)

themis biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.094
signal transduction GO:0007165 455 0.058
cellular macromolecule metabolic process GO:0044260 391 0.051
phagocytosis GO:0006909 3 0.049
nitrogen compound metabolic process GO:0006807 319 0.047
aging GO:0007568 2 0.047
biosynthetic process GO:0009058 294 0.045
organic substance biosynthetic process GO:1901576 289 0.044
cell surface receptor signaling pathway GO:0007166 325 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.043
maintenance of location GO:0051235 4 0.042
negative regulation of biological process GO:0048519 304 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.040
regulation of cellular metabolic process GO:0031323 320 0.040
positive regulation of transport GO:0051050 2 0.040
regulation of metabolic process GO:0019222 359 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
cellular protein catabolic process GO:0044257 4 0.038
rna metabolic process GO:0016070 219 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
generation of neurons GO:0048699 385 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
cell motility GO:0048870 244 0.035
cellular biosynthetic process GO:0044249 286 0.035
lipid storage GO:0019915 1 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
heterocycle metabolic process GO:0046483 290 0.034
nucleobase containing compound metabolic process GO:0006139 274 0.034
nucleic acid templated transcription GO:0097659 181 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.033
response to stress GO:0006950 263 0.033
cellular macromolecule biosynthetic process GO:0034645 224 0.033
regulation of developmental process GO:0050793 247 0.033
ubiquitin dependent protein catabolic process GO:0006511 3 0.033
single organism metabolic process GO:0044710 217 0.032
regulation of cell activation GO:0050865 1 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
locomotion GO:0040011 313 0.032
organic cyclic compound metabolic process GO:1901360 301 0.032
stem cell maintenance GO:0019827 4 0.031
transport GO:0006810 220 0.031
central nervous system development GO:0007417 387 0.031
regulation of biological quality GO:0065008 263 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
immune system process GO:0002376 241 0.031
regulation of multicellular organismal process GO:0051239 277 0.030
regulation of biosynthetic process GO:0009889 250 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
cell migration GO:0016477 237 0.030
localization of cell GO:0051674 244 0.030
positive regulation of catabolic process GO:0009896 4 0.030
neuron differentiation GO:0030182 353 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
regulation of response to stimulus GO:0048583 269 0.029
regulation of gene expression GO:0010468 265 0.029
cellular component morphogenesis GO:0032989 336 0.029
nucleic acid metabolic process GO:0090304 244 0.029
regionalization GO:0003002 274 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
proteasomal protein catabolic process GO:0010498 2 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
amine metabolic process GO:0009308 2 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
regulation of signal transduction GO:0009966 225 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
regulation of primary metabolic process GO:0080090 311 0.028
gene expression GO:0010467 252 0.028
regulation of cytokine production GO:0001817 3 0.028
transcription dna templated GO:0006351 181 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
regulation of rna metabolic process GO:0051252 224 0.027
protein acetylation GO:0006473 2 0.027
regulation of protein catabolic process GO:0042176 1 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
digestive system development GO:0055123 289 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
female sex differentiation GO:0046660 4 0.027
mononuclear cell proliferation GO:0032943 1 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
tube morphogenesis GO:0035239 349 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
leukocyte proliferation GO:0070661 1 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of signaling GO:0023051 235 0.026
response to external stimulus GO:0009605 264 0.026
sensory organ development GO:0007423 393 0.025
nuclear transport GO:0051169 4 0.025
centrosome organization GO:0051297 1 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
positive regulation of cellular process GO:0048522 201 0.025
neuron development GO:0048666 262 0.025
protein localization to nucleus GO:0034504 3 0.025
nuclear import GO:0051170 3 0.025
head development GO:0060322 303 0.025
protein metabolic process GO:0019538 183 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.024
protein acylation GO:0043543 3 0.024
rna biosynthetic process GO:0032774 181 0.024
cellular amine metabolic process GO:0044106 2 0.024
cell part morphogenesis GO:0032990 246 0.024
internal protein amino acid acetylation GO:0006475 2 0.024
regulation of protein transport GO:0051223 3 0.024
peptidyl lysine acetylation GO:0018394 2 0.024
cellular component movement GO:0006928 335 0.024
establishment of localization GO:0051234 244 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
brain development GO:0007420 293 0.024
regulation of protein localization to nucleus GO:1900180 2 0.023
protein import GO:0017038 3 0.023
positive regulation of cell activation GO:0050867 1 0.023
regulation of meiotic cell cycle GO:0051445 1 0.023
cell morphogenesis GO:0000902 289 0.023
positive regulation of cytokine production GO:0001819 2 0.023
meiotic nuclear division GO:0007126 4 0.023
development of primary female sexual characteristics GO:0046545 4 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.023
regulation of multicellular organism growth GO:0040014 4 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
female gonad development GO:0008585 4 0.022
response to chemical GO:0042221 320 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
negative regulation of cellular process GO:0048523 283 0.022
hemopoiesis GO:0030097 183 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
regulation of cell communication GO:0010646 232 0.022
meiotic cell cycle process GO:1903046 3 0.022
lymphocyte proliferation GO:0046651 1 0.022
regulation of transcription dna templated GO:0006355 213 0.022
gtp metabolic process GO:0046039 4 0.022
alternative mrna splicing via spliceosome GO:0000380 1 0.021
cellular response to external stimulus GO:0071496 2 0.021
cellular amide metabolic process GO:0043603 4 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
positive regulation of biological process GO:0048518 253 0.021
single organism organelle organization GO:1902589 199 0.021
chordate embryonic development GO:0043009 271 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
embryonic organ development GO:0048568 381 0.020
response to drug GO:0042493 3 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
single organism transport GO:0044765 206 0.020
cell projection organization GO:0030030 284 0.020
small molecule metabolic process GO:0044281 77 0.020
cell projection morphogenesis GO:0048858 244 0.020
oxoacid metabolic process GO:0043436 31 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
single organism localization GO:1902578 225 0.020
ameboidal type cell migration GO:0001667 143 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.019
cellular ketone metabolic process GO:0042180 11 0.019
cellular protein metabolic process GO:0044267 129 0.019
cellular component assembly GO:0022607 170 0.019
regulation of cell shape GO:0008360 1 0.019
gastrulation GO:0007369 208 0.019
determination of bilateral symmetry GO:0009855 204 0.019
digestive tract development GO:0048565 265 0.019
regulation of binding GO:0051098 3 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
positive regulation of immune effector process GO:0002699 3 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
compound eye development GO:0048749 2 0.019
organelle organization GO:0006996 227 0.019
system process GO:0003008 185 0.019
translational initiation GO:0006413 3 0.019
organic acid metabolic process GO:0006082 31 0.019
immune system development GO:0002520 191 0.018
single organism nuclear import GO:1902593 3 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
eye development GO:0001654 277 0.018
meiotic chromosome segregation GO:0045132 3 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
gtp catabolic process GO:0006184 2 0.018
response to monosaccharide GO:0034284 3 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
response to hexose GO:0009746 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
growth GO:0040007 174 0.017
protein secretion GO:0009306 1 0.017
positive regulation of translation GO:0045727 1 0.017
autophagy GO:0006914 4 0.017
regulation of protein targeting GO:1903533 2 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
response to glucose GO:0009749 3 0.017
cognition GO:0050890 1 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
cytokinesis GO:0000910 3 0.017
regulation of metal ion transport GO:0010959 4 0.016
negative regulation of nuclear division GO:0051784 3 0.016
regulation of inflammatory response GO:0050727 2 0.016
blood vessel development GO:0001568 246 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
specification of symmetry GO:0009799 204 0.016
macromolecule modification GO:0043412 111 0.016
phagocytosis engulfment GO:0006911 1 0.016
regulation of reproductive process GO:2000241 4 0.016
mitochondrion organization GO:0007005 4 0.016
protein targeting to nucleus GO:0044744 3 0.016
negative regulation of cytokine production GO:0001818 1 0.016
convergent extension GO:0060026 118 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
retina development in camera type eye GO:0060041 146 0.016
protein import into nucleus GO:0006606 3 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
microtubule organizing center organization GO:0031023 1 0.016
b cell activation GO:0042113 2 0.016
peptide transport GO:0015833 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
hormone transport GO:0009914 2 0.015
anterior posterior pattern specification GO:0009952 152 0.015
protein stabilization GO:0050821 2 0.015
glucose homeostasis GO:0042593 1 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
positive regulation of cell cycle GO:0045787 3 0.015
meiosis i GO:0007127 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
lipid homeostasis GO:0055088 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
antimicrobial humoral response GO:0019730 2 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
determination of left right symmetry GO:0007368 179 0.015
response to other organism GO:0051707 97 0.015
response to carbohydrate GO:0009743 3 0.015
digestive tract morphogenesis GO:0048546 231 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular component disassembly GO:0022411 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
toll like receptor signaling pathway GO:0002224 4 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
camera type eye development GO:0043010 222 0.014
regulation of hormone secretion GO:0046883 2 0.014
cellular response to starvation GO:0009267 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
carbohydrate homeostasis GO:0033500 1 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
protein polymerization GO:0051258 4 0.014
phosphorus metabolic process GO:0006793 109 0.014
regulation of chromosome segregation GO:0051983 1 0.014
regulation of cell differentiation GO:0045595 142 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
regulation of organelle assembly GO:1902115 4 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
positive regulation of metabolic process GO:0009893 108 0.014
interspecies interaction between organisms GO:0044419 4 0.014
vasculature development GO:0001944 278 0.014
adult behavior GO:0030534 2 0.014
locomotor rhythm GO:0045475 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
response to external biotic stimulus GO:0043207 97 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
membrane invagination GO:0010324 1 0.013
golgi vesicle transport GO:0048193 3 0.013
segmentation GO:0035282 97 0.013
heart development GO:0007507 313 0.013
gland development GO:0048732 143 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
blood circulation GO:0008015 87 0.013
cellular protein modification process GO:0006464 100 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
response to wounding GO:0009611 116 0.013
regulation of jun kinase activity GO:0043506 3 0.013
endosomal transport GO:0016197 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
cellular response to nutrient levels GO:0031669 2 0.013
hormone secretion GO:0046879 2 0.013
negative regulation of defense response GO:0031348 2 0.013
regulation of immune system process GO:0002682 34 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
atp catabolic process GO:0006200 4 0.013
spermatid development GO:0007286 2 0.013
spermatid differentiation GO:0048515 2 0.013
neuron projection development GO:0031175 180 0.013
cellular component biogenesis GO:0044085 178 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
rna localization GO:0006403 4 0.013
negative regulation of metabolic process GO:0009892 86 0.013
stem cell proliferation GO:0072089 4 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
regulation of gtpase activity GO:0043087 2 0.012
homeostatic process GO:0042592 142 0.012
regulation of blood pressure GO:0008217 1 0.012
tissue remodeling GO:0048771 4 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
sensory organ morphogenesis GO:0090596 200 0.012
response to biotic stimulus GO:0009607 97 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
cell substrate adhesion GO:0031589 4 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
protein localization to plasma membrane GO:0072659 1 0.012
regulation of localization GO:0032879 104 0.012
somitogenesis GO:0001756 87 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
sequestering of metal ion GO:0051238 3 0.012
mitotic cytokinesis GO:0000281 3 0.012
regulation of synapse assembly GO:0051963 3 0.012
regulation of autophagy GO:0010506 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
eye morphogenesis GO:0048592 144 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
circulatory system process GO:0003013 87 0.012
positive regulation of chromosome organization GO:2001252 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of synapse organization GO:0050807 3 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
response to uv GO:0009411 3 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
protein complex disassembly GO:0043241 1 0.011
spindle assembly GO:0051225 2 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of dna replication GO:0006275 3 0.011
cellular response to radiation GO:0071478 4 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
b cell differentiation GO:0030183 1 0.011
axon development GO:0061564 166 0.011
multi organism process GO:0051704 134 0.011
sequestering of calcium ion GO:0051208 3 0.011
macromolecular complex disassembly GO:0032984 1 0.011
neurological system process GO:0050877 62 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
regulation of neurogenesis GO:0050767 87 0.011
protein heterooligomerization GO:0051291 1 0.011
cellular response to organic substance GO:0071310 105 0.011
adherens junction organization GO:0034332 4 0.011
myeloid cell differentiation GO:0030099 86 0.011
somatic stem cell maintenance GO:0035019 1 0.011
ovulation cycle GO:0042698 2 0.011
actin filament polymerization GO:0030041 2 0.011
lamellipodium organization GO:0097581 1 0.011
cell cycle GO:0007049 93 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
exocytosis GO:0006887 1 0.011
muscle structure development GO:0061061 196 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
death GO:0016265 121 0.011
positive regulation of histone modification GO:0031058 1 0.010
membrane fusion GO:0061025 2 0.010
negative regulation of secretion GO:0051048 2 0.010
negative regulation of signaling GO:0023057 96 0.010
angiogenesis GO:0001525 158 0.010
wnt signaling pathway GO:0016055 80 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
cell matrix adhesion GO:0007160 4 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
somite development GO:0061053 96 0.010
response to organic substance GO:0010033 153 0.010
regulation of tube size GO:0035150 2 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
double strand break repair GO:0006302 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
cell death GO:0008219 121 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
response to nutrient GO:0007584 3 0.010
negative regulation of cell communication GO:0010648 96 0.010
neuron projection morphogenesis GO:0048812 161 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
developmental growth GO:0048589 166 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
negative regulation of multi organism process GO:0043901 3 0.010
activation of mapk activity GO:0000187 3 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010

themis disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.012
organ system cancer DOID:0050686 0 0.011