Danio rerio

0 known processes

pdp1

pyruvate dehyrogenase phosphatase catalytic subunit 1

(Aliases: im:7157162,zgc:174908)

pdp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.064
aging GO:0007568 2 0.049
cognition GO:0050890 1 0.035
multicellular organism growth GO:0035264 4 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
positive regulation of transport GO:0051050 2 0.034
maintenance of location GO:0051235 4 0.033
regulation of multicellular organism growth GO:0040014 4 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
modification dependent protein catabolic process GO:0019941 3 0.030
amine metabolic process GO:0009308 2 0.029
cellular protein catabolic process GO:0044257 4 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
positive regulation of cell cycle GO:0045787 3 0.026
cellular amine metabolic process GO:0044106 2 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
nitrogen compound metabolic process GO:0006807 319 0.026
meiotic nuclear division GO:0007126 4 0.025
phagocytosis GO:0006909 3 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
protein acetylation GO:0006473 2 0.025
nuclear transport GO:0051169 4 0.025
regulation of mrna processing GO:0050684 3 0.025
endosomal transport GO:0016197 2 0.025
stem cell maintenance GO:0019827 4 0.025
meiotic cell cycle process GO:1903046 3 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
positive regulation of catabolic process GO:0009896 4 0.024
autophagy GO:0006914 4 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
protein localization to nucleus GO:0034504 3 0.024
response to chemical GO:0042221 320 0.023
mitochondrion organization GO:0007005 4 0.023
protein import GO:0017038 3 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
compound eye development GO:0048749 2 0.023
regulation of protein catabolic process GO:0042176 1 0.023
exocytosis GO:0006887 1 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
protein import into nucleus GO:0006606 3 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
stem cell proliferation GO:0072089 4 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
lipid storage GO:0019915 1 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
cellular ketone metabolic process GO:0042180 11 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
signal transduction GO:0007165 455 0.022
regulation of protein transport GO:0051223 3 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
response to carbohydrate GO:0009743 3 0.022
regulation of metal ion transport GO:0010959 4 0.021
heterocycle metabolic process GO:0046483 290 0.021
adult behavior GO:0030534 2 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
system process GO:0003008 185 0.021
gtp catabolic process GO:0006184 2 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of reproductive process GO:2000241 4 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
regulation of synapse organization GO:0050807 3 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
internal protein amino acid acetylation GO:0006475 2 0.020
golgi vesicle transport GO:0048193 3 0.020
eye development GO:0001654 277 0.020
regulation of cytokine production GO:0001817 3 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
atp catabolic process GO:0006200 4 0.020
response to drug GO:0042493 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of cell activation GO:0050865 1 0.020
generation of neurons GO:0048699 385 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
negative regulation of biological process GO:0048519 304 0.019
gene expression GO:0010467 252 0.019
cell part morphogenesis GO:0032990 246 0.019
organic substance biosynthetic process GO:1901576 289 0.019
small molecule metabolic process GO:0044281 77 0.019
gtp metabolic process GO:0046039 4 0.019
regulation of protein complex assembly GO:0043254 3 0.019
organelle organization GO:0006996 227 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
protein acylation GO:0043543 3 0.019
immune system process GO:0002376 241 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
single fertilization GO:0007338 3 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
cytokinesis GO:0000910 3 0.019
organelle fusion GO:0048284 3 0.019
cellular component movement GO:0006928 335 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
protein polyubiquitination GO:0000209 4 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
negative regulation of catabolic process GO:0009895 3 0.019
cellular biosynthetic process GO:0044249 286 0.018
sensory organ development GO:0007423 393 0.018
nuclear import GO:0051170 3 0.018
cell projection organization GO:0030030 284 0.018
regulation of response to stimulus GO:0048583 269 0.018
secondary metabolic process GO:0019748 3 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
cellular response to nutrient levels GO:0031669 2 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
homeostatic process GO:0042592 142 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
protein targeting to nucleus GO:0044744 3 0.018
rna localization GO:0006403 4 0.018
positive regulation of cell activation GO:0050867 1 0.018
adherens junction organization GO:0034332 4 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
regulation of binding GO:0051098 3 0.018
organic acid metabolic process GO:0006082 31 0.018
single organism nuclear import GO:1902593 3 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
regulation of autophagy GO:0010506 3 0.018
regulation of multicellular organismal process GO:0051239 277 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of metabolic process GO:0019222 359 0.017
regulation of gene expression GO:0010468 265 0.017
cellular component morphogenesis GO:0032989 336 0.017
biosynthetic process GO:0009058 294 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
embryonic organ development GO:0048568 381 0.017
neuron differentiation GO:0030182 353 0.017
protein localization to plasma membrane GO:0072659 1 0.017
leukocyte proliferation GO:0070661 1 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
cell projection morphogenesis GO:0048858 244 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
regulation of signaling GO:0023051 235 0.017
single organism transport GO:0044765 206 0.017
membrane fusion GO:0061025 2 0.017
cellular component disassembly GO:0022411 1 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of cell shape GO:0008360 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
peptidyl serine modification GO:0018209 2 0.016
response to uv GO:0009411 3 0.016
regulation of biological quality GO:0065008 263 0.016
response to monosaccharide GO:0034284 3 0.016
chemosensory behavior GO:0007635 1 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
lipid homeostasis GO:0055088 3 0.016
response to hexose GO:0009746 3 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
positive regulation of secretion GO:0051047 1 0.016
cell morphogenesis GO:0000902 289 0.016
sequestering of calcium ion GO:0051208 3 0.016
protein dephosphorylation GO:0006470 3 0.016
neuroblast proliferation GO:0007405 2 0.016
establishment of localization GO:0051234 244 0.016
nucleic acid metabolic process GO:0090304 244 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of synapse assembly GO:0051963 3 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
nucleic acid templated transcription GO:0097659 181 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
fertilization GO:0009566 3 0.016
response to external stimulus GO:0009605 264 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
cell substrate adhesion GO:0031589 4 0.015
regulation of signal transduction GO:0009966 225 0.015
stem cell division GO:0017145 1 0.015
regulation of primary metabolic process GO:0080090 311 0.015
cell migration GO:0016477 237 0.015
tissue remodeling GO:0048771 4 0.015
single organism organelle organization GO:1902589 199 0.015
hemopoiesis GO:0030097 183 0.015
single organism membrane fusion GO:0044801 2 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
rna metabolic process GO:0016070 219 0.015
head development GO:0060322 303 0.015
negative regulation of nuclear division GO:0051784 3 0.015
regulation of sequestering of calcium ion GO:0051282 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
protein secretion GO:0009306 1 0.015
negative regulation of cellular process GO:0048523 283 0.015
transcription dna templated GO:0006351 181 0.015
regulation of cell communication GO:0010646 232 0.015
regulation of rna metabolic process GO:0051252 224 0.015
regulation of dendrite development GO:0050773 3 0.015
negative regulation of sequestering of calcium ion GO:0051283 4 0.015
cellular component assembly GO:0022607 170 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.014
carbohydrate homeostasis GO:0033500 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
response to glucose GO:0009749 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
mononuclear cell proliferation GO:0032943 1 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
response to stress GO:0006950 263 0.014
positive regulation of cytokine production GO:0001819 2 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
spermatid development GO:0007286 2 0.014
developmental growth GO:0048589 166 0.014
meiotic chromosome segregation GO:0045132 3 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
protein metabolic process GO:0019538 183 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
rna biosynthetic process GO:0032774 181 0.014
rna 3 end processing GO:0031123 2 0.014
double strand break repair GO:0006302 3 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
microtubule organizing center organization GO:0031023 1 0.014
b cell activation GO:0042113 2 0.014
intracellular mrna localization GO:0008298 1 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
tube morphogenesis GO:0035239 349 0.014
regulation of developmental process GO:0050793 247 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
heart development GO:0007507 313 0.014
neuron development GO:0048666 262 0.014
membrane invagination GO:0010324 1 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
female meiotic division GO:0007143 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
germ line stem cell maintenance GO:0030718 2 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
spermatid differentiation GO:0048515 2 0.013
regulation of blood pressure GO:0008217 1 0.013
central nervous system development GO:0007417 387 0.013
lymphocyte proliferation GO:0046651 1 0.013
regulation of transporter activity GO:0032409 2 0.013
single organism localization GO:1902578 225 0.013
mitochondrial transport GO:0006839 2 0.013
regulation of calcium ion transport GO:0051924 2 0.013
cellular response to radiation GO:0071478 4 0.013
response to organic substance GO:0010033 153 0.013
sequestering of metal ion GO:0051238 3 0.013
nuclear export GO:0051168 1 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
blood vessel development GO:0001568 246 0.013
regionalization GO:0003002 274 0.013
protein heterooligomerization GO:0051291 1 0.013
regulation of protein targeting GO:1903533 2 0.013
locomotion GO:0040011 313 0.013
cellular component biogenesis GO:0044085 178 0.013
primary neural tube formation GO:0014020 1 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
double strand break repair via homologous recombination GO:0000724 1 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
cellular respiration GO:0045333 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
chordate embryonic development GO:0043009 271 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
tube closure GO:0060606 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
cell matrix adhesion GO:0007160 4 0.013
positive regulation of immune effector process GO:0002699 3 0.013
centrosome organization GO:0051297 1 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
gastrulation GO:0007369 208 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
positive regulation of biological process GO:0048518 253 0.012
female sex differentiation GO:0046660 4 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
small molecule catabolic process GO:0044282 3 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
cellular response to oxygen levels GO:0071453 1 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of exocytosis GO:0017157 1 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
phagocytosis engulfment GO:0006911 1 0.012
peptide transport GO:0015833 1 0.012
locomotor rhythm GO:0045475 3 0.012
lateral inhibition GO:0046331 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
centrosome duplication GO:0051298 1 0.012
brain development GO:0007420 293 0.012
lipid catabolic process GO:0016042 4 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
immune system development GO:0002520 191 0.012
cellular response to starvation GO:0009267 1 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
localization of cell GO:0051674 244 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
antimicrobial humoral response GO:0019730 2 0.012
transport GO:0006810 220 0.012
protein modification process GO:0036211 100 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
camera type eye development GO:0043010 222 0.012
cellular response to light stimulus GO:0071482 4 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
synaptic vesicle transport GO:0048489 1 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of jak stat cascade GO:0046425 3 0.012
macromolecular complex disassembly GO:0032984 1 0.012
muscle structure development GO:0061061 196 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
protein homooligomerization GO:0051260 3 0.012
sensory perception of pain GO:0019233 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
mrna 3 end processing GO:0031124 2 0.012
cellular response to organic substance GO:0071310 105 0.012
organic acid catabolic process GO:0016054 3 0.012
organism emergence from protective structure GO:0071684 4 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
digestive system development GO:0055123 289 0.012
protein stabilization GO:0050821 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
negative regulation of cytokine production GO:0001818 1 0.011
peptide metabolic process GO:0006518 1 0.011
digestive tract morphogenesis GO:0048546 231 0.011
positive regulation of histone modification GO:0031058 1 0.011
response to corticosteroid GO:0031960 1 0.011
protein complex disassembly GO:0043241 1 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
cilium morphogenesis GO:0060271 85 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
sleep GO:0030431 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
cytoplasm organization GO:0007028 4 0.011
centrosome cycle GO:0007098 1 0.011
cellular protein metabolic process GO:0044267 129 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of transcription dna templated GO:0006355 213 0.011
negative regulation of defense response GO:0031348 2 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
vacuolar transport GO:0007034 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
positive regulation of translation GO:0045727 1 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
cellular response to hypoxia GO:0071456 1 0.011
regulation of blood vessel size GO:0050880 2 0.011
negative regulation of secretion GO:0051048 2 0.011
neurotransmitter secretion GO:0007269 2 0.011
post embryonic organ development GO:0048569 4 0.011
regulation of circadian rhythm GO:0042752 4 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
alcohol biosynthetic process GO:0046165 2 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
regulation of receptor activity GO:0010469 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
retina development in camera type eye GO:0060041 146 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
female gonad development GO:0008585 4 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
hormone secretion GO:0046879 2 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
growth GO:0040007 174 0.010
cellular amide metabolic process GO:0043603 4 0.010
regulation of dna replication GO:0006275 3 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
muscle cell development GO:0055001 115 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
mitotic cytokinesis GO:0000281 3 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
actin filament polymerization GO:0030041 2 0.010
eye morphogenesis GO:0048592 144 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
phosphatidylinositol mediated signaling GO:0048015 2 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
response to external biotic stimulus GO:0043207 97 0.010
neuron projection development GO:0031175 180 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
response to hydrogen peroxide GO:0042542 3 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010

pdp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.020
musculoskeletal system disease DOID:17 0 0.016
inherited metabolic disorder DOID:655 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011