Danio rerio

6 known processes

pnocb

prepronociceptin b

(Aliases: pnoc,zgc:136385,MGC136385)

pnocb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 277 0.095
regulation of multicellular organismal process GO:0051239 277 0.070
maintenance of location GO:0051235 4 0.060
response to drug GO:0042493 3 0.055
adult behavior GO:0030534 2 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.053
synaptic growth at neuromuscular junction GO:0051124 2 0.051
regulation of cytokine production GO:0001817 3 0.048
axon ensheathment in central nervous system GO:0032291 2 0.048
regulation of establishment of protein localization GO:0070201 4 0.047
aging GO:0007568 2 0.047
nucleobase containing compound metabolic process GO:0006139 274 0.044
positive regulation of transport GO:0051050 2 0.043
sensory organ development GO:0007423 393 0.042
regulation of blood pressure GO:0008217 1 0.042
regulation of developmental process GO:0050793 247 0.042
regulation of multicellular organismal development GO:2000026 223 0.041
regulation of reproductive process GO:2000241 4 0.038
embryonic organ morphogenesis GO:0048562 274 0.038
glucose homeostasis GO:0042593 1 0.038
morphogenesis of an epithelium GO:0002009 333 0.038
regulation of biological quality GO:0065008 263 0.037
larval development GO:0002164 2 0.037
regulation of muscle contraction GO:0006937 3 0.037
neuron differentiation GO:0030182 353 0.036
chordate embryonic development GO:0043009 271 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.035
lipid storage GO:0019915 1 0.034
regulation of cell differentiation GO:0045595 142 0.034
cognition GO:0050890 1 0.033
single organism localization GO:1902578 225 0.032
positive regulation of cytokine production GO:0001819 2 0.032
camera type eye development GO:0043010 222 0.032
response to external stimulus GO:0009605 264 0.031
regulation of protein complex assembly GO:0043254 3 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
hormone transport GO:0009914 2 0.031
biosynthetic process GO:0009058 294 0.031
endocrine process GO:0050886 2 0.031
multicellular organism growth GO:0035264 4 0.031
specification of symmetry GO:0009799 204 0.030
blood circulation GO:0008015 87 0.030
guanosine containing compound metabolic process GO:1901068 4 0.030
embryonic organ development GO:0048568 381 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
cellular component biogenesis GO:0044085 178 0.030
system process GO:0003008 185 0.029
cellular component morphogenesis GO:0032989 336 0.028
regulation of systemic arterial blood pressure GO:0003073 1 0.028
protein polymerization GO:0051258 4 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
regulation of circadian rhythm GO:0042752 4 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
neuron development GO:0048666 262 0.027
sequestering of metal ion GO:0051238 3 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
response to stress GO:0006950 263 0.027
generation of neurons GO:0048699 385 0.027
heart development GO:0007507 313 0.027
positive regulation of blood circulation GO:1903524 2 0.027
gene expression GO:0010467 252 0.027
response to glucose GO:0009749 3 0.026
muscle cell development GO:0055001 115 0.026
carbohydrate homeostasis GO:0033500 1 0.026
cell part morphogenesis GO:0032990 246 0.026
cellular component movement GO:0006928 335 0.026
regulation of primary metabolic process GO:0080090 311 0.026
cell morphogenesis GO:0000902 289 0.026
segmentation GO:0035282 97 0.026
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.026
determination of left right symmetry GO:0007368 179 0.026
central nervous system development GO:0007417 387 0.026
compound eye development GO:0048749 2 0.026
heterocycle metabolic process GO:0046483 290 0.026
phagocytosis GO:0006909 3 0.026
hormone secretion GO:0046879 2 0.025
tube morphogenesis GO:0035239 349 0.025
determination of bilateral symmetry GO:0009855 204 0.025
cellular response to external stimulus GO:0071496 2 0.025
gtp catabolic process GO:0006184 2 0.025
positive regulation of catabolic process GO:0009896 4 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
regulation of epithelial cell proliferation GO:0050678 3 0.025
regulation of biosynthetic process GO:0009889 250 0.024
organic substance biosynthetic process GO:1901576 289 0.024
cellular component disassembly GO:0022411 1 0.024
single organism transport GO:0044765 206 0.024
embryonic skeletal system development GO:0048706 97 0.024
embryonic heart tube development GO:0035050 133 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
muscle structure development GO:0061061 196 0.024
transmembrane transport GO:0055085 120 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
sensory organ morphogenesis GO:0090596 200 0.023
retina development in camera type eye GO:0060041 146 0.023
regulation of blood vessel size GO:0050880 2 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
homeostatic process GO:0042592 142 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
wound healing GO:0042060 90 0.023
cellular response to organic substance GO:0071310 105 0.023
synaptic vesicle transport GO:0048489 1 0.023
small molecule metabolic process GO:0044281 77 0.023
ion transmembrane transport GO:0034220 91 0.023
signal transduction GO:0007165 455 0.023
regulation of multicellular organism growth GO:0040014 4 0.022
regulation of tube size GO:0035150 2 0.022
response to abiotic stimulus GO:0009628 122 0.022
response to external biotic stimulus GO:0043207 97 0.022
rna localization GO:0006403 4 0.022
skeletal system morphogenesis GO:0048705 102 0.022
g protein coupled receptor signaling pathway GO:0007186 74 0.021
cellular biosynthetic process GO:0044249 286 0.021
positive regulation of secretion GO:0051047 1 0.021
regulation of protein polymerization GO:0032271 2 0.021
regulation of metabolic process GO:0019222 359 0.021
circulatory system process GO:0003013 87 0.021
neurotransmitter transport GO:0006836 2 0.021
sequestering of calcium ion GO:0051208 3 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
cellular response to biotic stimulus GO:0071216 3 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
golgi vesicle transport GO:0048193 3 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
cell projection organization GO:0030030 284 0.020
gtp metabolic process GO:0046039 4 0.020
meiotic nuclear division GO:0007126 4 0.020
response to carbohydrate GO:0009743 3 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
cellular amide metabolic process GO:0043603 4 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
regulation of hormone secretion GO:0046883 2 0.020
nucleic acid metabolic process GO:0090304 244 0.020
regulation of autophagy GO:0010506 3 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
synaptic vesicle localization GO:0097479 1 0.020
stem cell proliferation GO:0072089 4 0.020
somitogenesis GO:0001756 87 0.020
response to monosaccharide GO:0034284 3 0.020
head development GO:0060322 303 0.019
striated muscle cell development GO:0055002 108 0.019
inorganic anion transport GO:0015698 25 0.019
regulation of sequestering of calcium ion GO:0051282 4 0.019
regulation of neurogenesis GO:0050767 87 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
transport GO:0006810 220 0.019
single organism behavior GO:0044708 24 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
regulation of epidermis development GO:0045682 2 0.019
kidney development GO:0001822 92 0.019
rna biosynthetic process GO:0032774 181 0.018
neurological system process GO:0050877 62 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
pronephros development GO:0048793 69 0.018
multi organism process GO:0051704 134 0.018
single organism membrane fusion GO:0044801 2 0.018
regulation of nervous system development GO:0051960 90 0.018
production of molecular mediator of immune response GO:0002440 2 0.018
cell projection morphogenesis GO:0048858 244 0.018
negative regulation of biological process GO:0048519 304 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
heart contraction GO:0060047 71 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
development of primary female sexual characteristics GO:0046545 4 0.017
response to hexose GO:0009746 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
urogenital system development GO:0001655 97 0.017
stem cell maintenance GO:0019827 4 0.017
sensory perception of pain GO:0019233 1 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
protein metabolic process GO:0019538 183 0.017
membrane fusion GO:0061025 2 0.017
protein localization to plasma membrane GO:0072659 1 0.017
regulation of metal ion transport GO:0010959 4 0.017
response to topologically incorrect protein GO:0035966 2 0.017
autophagy GO:0006914 4 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
peptide transport GO:0015833 1 0.017
response to amino acid GO:0043200 2 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.016
exocytosis GO:0006887 1 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
establishment of localization GO:0051234 244 0.016
response to other organism GO:0051707 97 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
ion transport GO:0006811 114 0.016
spermatid differentiation GO:0048515 2 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
somite development GO:0061053 96 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
mitochondrion organization GO:0007005 4 0.016
endocrine hormone secretion GO:0060986 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
regulation of wound healing GO:0061041 2 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
female gonad development GO:0008585 4 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
epidermis development GO:0008544 48 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
cytoplasm organization GO:0007028 4 0.015
response to hydrogen peroxide GO:0042542 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of cell shape GO:0008360 1 0.015
muscle cell differentiation GO:0042692 139 0.015
regulation of protein transport GO:0051223 3 0.015
glial cell migration GO:0008347 3 0.015
cell fate commitment GO:0045165 99 0.015
entrainment of circadian clock GO:0009649 2 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
organic substance transport GO:0071702 58 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
organelle assembly GO:0070925 110 0.015
establishment of localization in cell GO:0051649 77 0.015
chemosensory behavior GO:0007635 1 0.015
regulation of cell projection assembly GO:0060491 4 0.015
protein acetylation GO:0006473 2 0.015
response to biotic stimulus GO:0009607 97 0.014
activation of mapk activity GO:0000187 3 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
cranial nerve development GO:0021545 42 0.014
neurotransmitter secretion GO:0007269 2 0.014
response to alkaloid GO:0043279 2 0.014
regulation of localization GO:0032879 104 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
response to chemical GO:0042221 320 0.014
smooth muscle contraction GO:0006939 2 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
neuron projection morphogenesis GO:0048812 161 0.014
regulation of gene expression GO:0010468 265 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
macromolecule modification GO:0043412 111 0.014
spermatid development GO:0007286 2 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
immune effector process GO:0002252 23 0.014
central nervous system myelination GO:0022010 2 0.014
response to nutrient GO:0007584 3 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
negative regulation of cellular process GO:0048523 283 0.014
negative regulation of catabolic process GO:0009895 3 0.014
cellular response to starvation GO:0009267 1 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of protein catabolic process GO:0042176 1 0.014
nucleocytoplasmic transport GO:0006913 4 0.013
cranial ganglion development GO:0061550 3 0.013
action potential GO:0001508 19 0.013
regulation of binding GO:0051098 3 0.013
vasculature development GO:0001944 278 0.013
negative regulation of kinase activity GO:0033673 4 0.013
rna metabolic process GO:0016070 219 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
epidermal cell fate specification GO:0009957 4 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
muscle organ development GO:0007517 101 0.013
striated muscle tissue development GO:0014706 110 0.013
organic acid metabolic process GO:0006082 31 0.013
cellular localization GO:0051641 97 0.013
cellular component assembly GO:0022607 170 0.013
germ line stem cell maintenance GO:0030718 2 0.013
organism emergence from protective structure GO:0071684 4 0.013
protein acylation GO:0043543 3 0.013
post embryonic organ development GO:0048569 4 0.013
lateral inhibition GO:0046331 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
macromolecular complex disassembly GO:0032984 1 0.013
fatty acid transport GO:0015908 1 0.013
rhombomere 5 development GO:0021571 4 0.013
female sex differentiation GO:0046660 4 0.013
keratinocyte differentiation GO:0030216 0 0.013
dicarboxylic acid transport GO:0006835 1 0.013
protein complex disassembly GO:0043241 1 0.013
anterior posterior pattern specification GO:0009952 152 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
nephron morphogenesis GO:0072028 2 0.013
tissue remodeling GO:0048771 4 0.013
nuclear export GO:0051168 1 0.012
developmental programmed cell death GO:0010623 4 0.012
angiogenesis GO:0001525 158 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
nuclear transport GO:0051169 4 0.012
cellular amine metabolic process GO:0044106 2 0.012
amino acid transport GO:0006865 2 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
intracellular mrna localization GO:0008298 1 0.012
response to wounding GO:0009611 116 0.012
small molecule catabolic process GO:0044282 3 0.012
cytokinesis GO:0000910 3 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
b cell activation GO:0042113 2 0.012
sympathetic nervous system development GO:0048485 3 0.012
sensory perception of smell GO:0007608 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
eye photoreceptor cell differentiation GO:0001754 45 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
axon development GO:0061564 166 0.012
cell substrate adhesion GO:0031589 4 0.012
type b pancreatic cell development GO:0003323 4 0.012
protein homooligomerization GO:0051260 3 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
regionalization GO:0003002 274 0.012
fertilization GO:0009566 3 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
locomotion GO:0040011 313 0.012
camera type eye morphogenesis GO:0048593 108 0.012
regulation of synapse organization GO:0050807 3 0.012
detection of chemical stimulus GO:0009593 4 0.012
alcohol biosynthetic process GO:0046165 2 0.012
actomyosin structure organization GO:0031032 53 0.012
regulation of cellular component organization GO:0051128 86 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
hindbrain development GO:0030902 91 0.012
water homeostasis GO:0030104 4 0.012
dicarboxylic acid metabolic process GO:0043648 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
regulation of rna metabolic process GO:0051252 224 0.012
regulation of oocyte development GO:0060281 3 0.012
brain development GO:0007420 293 0.012
regulation of lipid transport GO:0032368 4 0.012
regulation of inflammatory response GO:0050727 2 0.012
regulation of mrna processing GO:0050684 3 0.012
protein localization to nucleus GO:0034504 3 0.011
regulation of endocrine process GO:0044060 2 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
blood vessel development GO:0001568 246 0.011
cell migration GO:0016477 237 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of response to stimulus GO:0048583 269 0.011
muscle fiber development GO:0048747 52 0.011
membrane hyperpolarization GO:0060081 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of cell development GO:0060284 100 0.011
response to oxygen containing compound GO:1901700 55 0.011
macromolecule localization GO:0033036 54 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
positive regulation of heart contraction GO:0045823 2 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
translational initiation GO:0006413 3 0.011
somatic stem cell maintenance GO:0035019 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
endosomal transport GO:0016197 2 0.011
myofibril assembly GO:0030239 48 0.011
neuroblast proliferation GO:0007405 2 0.011
striated muscle cell differentiation GO:0051146 129 0.011
ameboidal type cell migration GO:0001667 143 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
cellular response to nutrient levels GO:0031669 2 0.011
epithelial cell differentiation GO:0030855 116 0.011
response to light stimulus GO:0009416 46 0.011
single organism organelle organization GO:1902589 199 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
secondary metabolic process GO:0019748 3 0.011
nerve development GO:0021675 45 0.011
meiotic chromosome segregation GO:0045132 3 0.011
regulation of lyase activity GO:0051339 12 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
taxis GO:0042330 109 0.011
hatching GO:0035188 4 0.011
locomotory behavior GO:0007626 34 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
regulation of transcription dna templated GO:0006355 213 0.011
cation transport GO:0006812 81 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
cell fate specification GO:0001708 68 0.011
steroid hormone secretion GO:0035929 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
nitrogen compound transport GO:0071705 23 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
response to organic substance GO:0010033 153 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
skeletal muscle organ development GO:0060538 78 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
positive regulation of reproductive process GO:2000243 2 0.011
membrane invagination GO:0010324 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
phototransduction GO:0007602 2 0.010
morphogenesis of an epithelial sheet GO:0002011 49 0.010
atp catabolic process GO:0006200 4 0.010
single fertilization GO:0007338 3 0.010
antimicrobial humoral response GO:0019730 2 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
organelle organization GO:0006996 227 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
cellular ketone metabolic process GO:0042180 11 0.010
mesenchyme development GO:0060485 127 0.010
cellular response to endogenous stimulus GO:0071495 68 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
positive regulation of epithelial cell differentiation GO:0030858 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
digestive system development GO:0055123 289 0.010
cellular response to radiation GO:0071478 4 0.010
regulation of striated muscle contraction GO:0006942 2 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
regulation of synapse assembly GO:0051963 3 0.010
leukocyte proliferation GO:0070661 1 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
pole plasm assembly GO:0007315 4 0.010
mechanosensory behavior GO:0007638 2 0.010
hemopoiesis GO:0030097 183 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010

pnocb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.078
nervous system disease DOID:863 0 0.029
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.012
immune system disease DOID:2914 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
musculoskeletal system disease DOID:17 0 0.010