Danio rerio

0 known processes

gclc

glutamate-cysteine ligase, catalytic subunit

(Aliases: fe36e11,wu:fe36e11,cb1049)

gclc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular modified amino acid metabolic process GO:0006575 3 0.695
Human Mouse
cellular amide metabolic process GO:0043603 4 0.635
Human Mouse
regulation of metabolic process GO:0019222 359 0.566
Human Mouse
positive regulation of biological process GO:0048518 253 0.501
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.480
Human
positive regulation of cellular process GO:0048522 201 0.445
Mouse
sulfur compound metabolic process GO:0006790 13 0.435
Human Mouse
small molecule metabolic process GO:0044281 77 0.385
Human Mouse
regulation of metal ion transport GO:0010959 4 0.383
heterocycle metabolic process GO:0046483 290 0.380
Human
response to external stimulus GO:0009605 264 0.363
cellular nitrogen compound biosynthetic process GO:0044271 218 0.357
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.347
Human
mitochondrial transport GO:0006839 2 0.329
signal transduction GO:0007165 455 0.324
Mouse
regulation of signal transduction GO:0009966 225 0.307
Mouse
regulation of cellular metabolic process GO:0031323 320 0.281
Human Mouse
larval development GO:0002164 2 0.278
nitrogen compound metabolic process GO:0006807 319 0.270
Human Mouse
hemopoiesis GO:0030097 183 0.259
transport GO:0006810 220 0.246
multicellular organism growth GO:0035264 4 0.236
negative regulation of cellular process GO:0048523 283 0.234
Human Mouse
single organism metabolic process GO:0044710 217 0.220
Human Mouse
establishment of protein localization to organelle GO:0072594 4 0.217
establishment of localization GO:0051234 244 0.216
regulation of multicellular organismal process GO:0051239 277 0.215
aging GO:0007568 2 0.212
cellular response to external stimulus GO:0071496 2 0.211
protein targeting to nucleus GO:0044744 3 0.209
peptide metabolic process GO:0006518 1 0.204
Human Mouse
response to nutrient GO:0007584 3 0.202
response to stress GO:0006950 263 0.201
Human
biosynthetic process GO:0009058 294 0.197
Human Mouse
regulation of response to stimulus GO:0048583 269 0.196
Mouse
nucleocytoplasmic transport GO:0006913 4 0.188
organonitrogen compound metabolic process GO:1901564 74 0.176
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.167
Human Mouse
immune system development GO:0002520 191 0.159
nucleobase containing compound metabolic process GO:0006139 274 0.157
Human
immune system process GO:0002376 241 0.153
protein import GO:0017038 3 0.150
regulation of intracellular protein transport GO:0033157 3 0.150
regulation of cell communication GO:0010646 232 0.145
Mouse
dicarboxylic acid metabolic process GO:0043648 1 0.142
Human
regulation of primary metabolic process GO:0080090 311 0.139
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.139
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.130
Human Mouse
regulation of tube size GO:0035150 2 0.127
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.125
regulation of cellular biosynthetic process GO:0031326 245 0.121
Human
cellular response to nutrient levels GO:0031669 2 0.119
response to drug GO:0042493 3 0.119
defense response GO:0006952 47 0.118
nuclear import GO:0051170 3 0.118
regulation of nucleoside metabolic process GO:0009118 2 0.117
aromatic compound biosynthetic process GO:0019438 217 0.116
Human
positive regulation of transport GO:0051050 2 0.115
nuclear transport GO:0051169 4 0.114
cellular localization GO:0051641 97 0.113
intracellular signal transduction GO:0035556 85 0.111
enzyme linked receptor protein signaling pathway GO:0007167 106 0.109
death GO:0016265 121 0.107
Human Mouse
leukocyte differentiation GO:0002521 25 0.104
cell proliferation GO:0008283 80 0.104
regulation of multicellular organism growth GO:0040014 4 0.103
carboxylic acid metabolic process GO:0019752 22 0.102
Human Mouse
transmembrane transport GO:0055085 120 0.101
guanosine containing compound metabolic process GO:1901068 4 0.100
positive regulation of metabolic process GO:0009893 108 0.099
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.097
cellular response to extracellular stimulus GO:0031668 2 0.096
single organism nuclear import GO:1902593 3 0.096
regulation of transcription dna templated GO:0006355 213 0.094
Human
negative regulation of protein phosphorylation GO:0001933 4 0.093
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.093
Human
rna metabolic process GO:0016070 219 0.091
Human
protein import into nucleus GO:0006606 3 0.089
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.088
sulfur compound transport GO:0072348 3 0.087
regulation of blood vessel size GO:0050880 2 0.087
Human
single organism localization GO:1902578 225 0.085
phosphorus metabolic process GO:0006793 109 0.084
embryo development ending in birth or egg hatching GO:0009792 271 0.084
guanosine containing compound catabolic process GO:1901069 2 0.084
regulation of intracellular signal transduction GO:1902531 57 0.082
organic acid metabolic process GO:0006082 31 0.082
Human Mouse
maintenance of location GO:0051235 4 0.081
regulation of nucleocytoplasmic transport GO:0046822 2 0.081
cellular amino acid metabolic process GO:0006520 7 0.081
Human Mouse
system process GO:0003008 185 0.081
Human
gtp metabolic process GO:0046039 4 0.081
response to chemical GO:0042221 320 0.080
Human Mouse
intracellular transport GO:0046907 32 0.079
regulation of nucleotide catabolic process GO:0030811 2 0.079
regulation of cell death GO:0010941 103 0.078
Human Mouse
response to copper ion GO:0046688 13 0.077
cellular macromolecule metabolic process GO:0044260 391 0.077
Human Mouse
negative regulation of biological process GO:0048519 304 0.076
Human Mouse
gtp catabolic process GO:0006184 2 0.075
regulation of biological quality GO:0065008 263 0.075
Human Mouse
cellular biosynthetic process GO:0044249 286 0.074
Human Mouse
regulation of establishment of protein localization GO:0070201 4 0.074
ion transport GO:0006811 114 0.073
growth GO:0040007 174 0.073
er nucleus signaling pathway GO:0006984 2 0.071
phosphate containing compound metabolic process GO:0006796 108 0.070
regulation of signaling GO:0023051 235 0.070
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.069
regulation of nitrogen compound metabolic process GO:0051171 251 0.069
Human
transcription dna templated GO:0006351 181 0.068
Human
production of molecular mediator of immune response GO:0002440 2 0.068
organic cyclic compound biosynthetic process GO:1901362 223 0.068
Human
cellular response to starvation GO:0009267 1 0.068
alpha amino acid metabolic process GO:1901605 3 0.066
Human
protein localization to nucleus GO:0034504 3 0.064
response to abiotic stimulus GO:0009628 122 0.063
Human
regulation of protein import into nucleus GO:0042306 2 0.061
oxidation reduction process GO:0055114 41 0.061
carboxylic acid catabolic process GO:0046395 3 0.061
positive regulation of cellular catabolic process GO:0031331 3 0.060
Mouse
regulation of protein targeting GO:1903533 2 0.057
oxalate transport GO:0019532 1 0.057
monovalent inorganic cation transport GO:0015672 42 0.056
positive regulation of nucleotide catabolic process GO:0030813 1 0.056
response to oxidative stress GO:0006979 11 0.056
Human
response to topologically incorrect protein GO:0035966 2 0.056
positive regulation of macromolecule metabolic process GO:0010604 93 0.055
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.055
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.055
phosphorylation GO:0016310 69 0.055
nucleic acid metabolic process GO:0090304 244 0.053
Human
ion homeostasis GO:0050801 41 0.053
Mouse
oxoacid metabolic process GO:0043436 31 0.053
Human Mouse
nucleotide biosynthetic process GO:0009165 21 0.053
regulation of localization GO:0032879 104 0.052
amide biosynthetic process GO:0043604 1 0.051
Human Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.051
Human
sodium ion transmembrane transport GO:0035725 21 0.050
cellular protein metabolic process GO:0044267 129 0.050
Mouse
antimicrobial humoral response GO:0019730 2 0.050
purine nucleotide metabolic process GO:0006163 27 0.050
regulation of membrane potential GO:0042391 23 0.048
Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.048
regulation of calcium ion transport GO:0051924 2 0.047
cell death GO:0008219 121 0.047
Human Mouse
negative regulation of response to stimulus GO:0048585 104 0.047
Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.047
regulation of sodium ion transport GO:0002028 2 0.047
regulation of macromolecule biosynthetic process GO:0010556 225 0.046
Human
lipid storage GO:0019915 1 0.046
central nervous system development GO:0007417 387 0.046
single organism intracellular transport GO:1902582 25 0.046
regulation of gtpase activity GO:0043087 2 0.044
locomotion GO:0040011 313 0.044
establishment of localization in cell GO:0051649 77 0.044
regulation of reproductive process GO:2000241 4 0.044
regulation of rna biosynthetic process GO:2001141 213 0.043
Human
positive regulation of catabolic process GO:0009896 4 0.043
Mouse
positive regulation of cytokine production GO:0001819 2 0.043
single organism transport GO:0044765 206 0.043
regulation of gene expression GO:0010468 265 0.042
Human
regulation of binding GO:0051098 3 0.042
nucleoside phosphate metabolic process GO:0006753 28 0.042
response to other organism GO:0051707 97 0.041
cell projection organization GO:0030030 284 0.041
programmed cell death GO:0012501 119 0.041
Human Mouse
regulation of response to stress GO:0080134 36 0.041
regulation of gtp catabolic process GO:0033124 2 0.040
nucleoside phosphate biosynthetic process GO:1901293 21 0.040
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.040
negative regulation of kinase activity GO:0033673 4 0.040
cellular response to organic substance GO:0071310 105 0.040
erythrocyte homeostasis GO:0034101 55 0.040
lipid catabolic process GO:0016042 4 0.040
regulation of protein localization to nucleus GO:1900180 2 0.039
heterocycle biosynthetic process GO:0018130 215 0.039
Human
neuron development GO:0048666 262 0.039
negative regulation of mapk cascade GO:0043409 4 0.039
regulation of cytokine production GO:0001817 3 0.039
organelle organization GO:0006996 227 0.039
Mouse
response to organic substance GO:0010033 153 0.038
Human
gene expression GO:0010467 252 0.038
Human
endoplasmic reticulum unfolded protein response GO:0030968 2 0.038
macromolecule modification GO:0043412 111 0.037
Mouse
cellular response to molecule of bacterial origin GO:0071219 3 0.037
response to biotic stimulus GO:0009607 97 0.037
ribonucleoside metabolic process GO:0009119 11 0.037
regulation of ion transmembrane transporter activity GO:0032412 2 0.037
cellular carbohydrate metabolic process GO:0044262 4 0.036
response to inorganic substance GO:0010035 38 0.036
positive regulation of nucleoside metabolic process GO:0045979 1 0.036
homeostasis of number of cells GO:0048872 62 0.036
ribonucleoside monophosphate catabolic process GO:0009158 4 0.036
myeloid cell differentiation GO:0030099 86 0.036
hydrogen peroxide metabolic process GO:0042743 2 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.036
protein complex localization GO:0031503 1 0.035
nucleobase containing small molecule metabolic process GO:0055086 32 0.035
regulation of programmed cell death GO:0043067 101 0.035
Human Mouse
purine nucleotide biosynthetic process GO:0006164 20 0.035
long chain fatty acid metabolic process GO:0001676 1 0.035
regulation of apoptotic process GO:0042981 98 0.034
Human Mouse
cation transport GO:0006812 81 0.034
rna biosynthetic process GO:0032774 181 0.034
Human
cation transmembrane transport GO:0098655 65 0.034
regulation of phosphorus metabolic process GO:0051174 43 0.034
reproduction GO:0000003 40 0.033
embryonic pattern specification GO:0009880 44 0.033
ion transmembrane transport GO:0034220 91 0.033
regionalization GO:0003002 274 0.033
regulation of dna templated transcription in response to stress GO:0043620 0 0.033
erk1 and erk2 cascade GO:0070371 4 0.032
cellular response to chemical stimulus GO:0070887 157 0.032
mitochondrion organization GO:0007005 4 0.031
Mouse
organophosphate metabolic process GO:0019637 37 0.031
neurological system process GO:0050877 62 0.031
leukocyte proliferation GO:0070661 1 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
purine nucleoside monophosphate catabolic process GO:0009128 4 0.031
compound eye development GO:0048749 2 0.031
nucleic acid templated transcription GO:0097659 181 0.030
Human
positive regulation of cellular amine metabolic process GO:0033240 0 0.030
cellular amino acid biosynthetic process GO:0008652 2 0.030
Human Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.030
stem cell development GO:0048864 82 0.030
regulation of transport GO:0051049 45 0.029
lipid metabolic process GO:0006629 52 0.029
immune effector process GO:0002252 23 0.029
response to unfolded protein GO:0006986 2 0.029
response to alkaloid GO:0043279 2 0.029
developmental growth GO:0048589 166 0.029
regulation of rna metabolic process GO:0051252 224 0.029
Human
single organism biosynthetic process GO:0044711 71 0.029
Human Mouse
regulation of cell motility GO:2000145 46 0.029
organonitrogen compound biosynthetic process GO:1901566 47 0.029
Human Mouse
regulation of molecular function GO:0065009 70 0.028
cellular response to stress GO:0033554 62 0.028
microtubule based process GO:0007017 60 0.028
i kappab kinase nf kappab signaling GO:0007249 4 0.028
immune response regulating signaling pathway GO:0002764 5 0.028
regulation of transporter activity GO:0032409 2 0.027
regulation of erk1 and erk2 cascade GO:0070372 4 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
Human Mouse
brain development GO:0007420 293 0.027
regulation of immune response GO:0050776 14 0.027
calcium ion transport into cytosol GO:0060402 3 0.027
b cell activation GO:0042113 2 0.027
organic substance transport GO:0071702 58 0.027
anion transport GO:0006820 38 0.026
cellular response to biotic stimulus GO:0071216 3 0.026
negative regulation of apoptotic process GO:0043066 55 0.026
Human Mouse
macromolecule localization GO:0033036 54 0.026
peptide transport GO:0015833 1 0.026
negative regulation of cell communication GO:0010648 96 0.026
Mouse
apoptotic process GO:0006915 116 0.026
Human Mouse
ovulation cycle GO:0042698 2 0.026
negative regulation of intracellular signal transduction GO:1902532 22 0.026
negative regulation of signaling GO:0023057 96 0.026
Mouse
blood circulation GO:0008015 87 0.026
Human
cellular response to topologically incorrect protein GO:0035967 2 0.025
carbohydrate derivative metabolic process GO:1901135 61 0.025
response to vitamin b3 GO:0033552 2 0.025
regulation of carbohydrate metabolic process GO:0006109 4 0.025
androgen metabolic process GO:0008209 2 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
Human
inorganic cation transmembrane transport GO:0098662 50 0.024
regulation of sodium ion transmembrane transporter activity GO:2000649 1 0.024
cellular response to unfolded protein GO:0034620 2 0.024
response to glucose GO:0009749 3 0.024
response to metal ion GO:0010038 34 0.024
negative regulation of blood circulation GO:1903523 2 0.024
positive regulation of immune effector process GO:0002699 3 0.024
leukocyte mediated cytotoxicity GO:0001909 1 0.024
inositol lipid mediated signaling GO:0048017 2 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.024
Human
cell surface receptor signaling pathway GO:0007166 325 0.024
Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.024
Human Mouse
nucleoside metabolic process GO:0009116 11 0.023
development of primary female sexual characteristics GO:0046545 4 0.023
regulation of purine nucleotide metabolic process GO:1900542 17 0.023
amine metabolic process GO:0009308 2 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
mapk cascade GO:0000165 18 0.022
neuron differentiation GO:0030182 353 0.022
response to external biotic stimulus GO:0043207 97 0.022
mononuclear cell proliferation GO:0032943 1 0.022
cytoplasm organization GO:0007028 4 0.022
stem cell proliferation GO:0072089 4 0.022
regulation of nucleotide metabolic process GO:0006140 17 0.022
positive regulation of blood circulation GO:1903524 2 0.022
positive regulation of gene expression GO:0010628 71 0.022
organic acid catabolic process GO:0016054 3 0.022
cell projection morphogenesis GO:0048858 244 0.022
regulation of sodium ion transmembrane transport GO:1902305 1 0.022
atp catabolic process GO:0006200 4 0.021
blood vessel morphogenesis GO:0048514 216 0.021
generation of neurons GO:0048699 385 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
Mouse
positive regulation of response to stimulus GO:0048584 80 0.021
nucleoside biosynthetic process GO:0009163 2 0.021
regulation of immune system process GO:0002682 34 0.021
response to vitamin GO:0033273 3 0.021
small molecule catabolic process GO:0044282 3 0.021
response to transition metal nanoparticle GO:1990267 28 0.021
neurotransmitter secretion GO:0007269 2 0.021
ribose phosphate metabolic process GO:0019693 27 0.021
multi organism process GO:0051704 134 0.021
cellular protein localization GO:0034613 20 0.021
protein targeting to membrane GO:0006612 1 0.021
purine containing compound metabolic process GO:0072521 29 0.021
regulation of protein complex assembly GO:0043254 3 0.021
regulation of protein transport GO:0051223 3 0.021
response to bacterium GO:0009617 58 0.021
protein metabolic process GO:0019538 183 0.020
Mouse
ovulation cycle process GO:0022602 2 0.020
positive regulation of signal transduction GO:0009967 56 0.020
positive regulation of nucleotide metabolic process GO:0045981 9 0.020
regulation of neurotransmitter secretion GO:0046928 1 0.020
regulation of transmembrane transporter activity GO:0022898 2 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.020
Mouse
synaptic transmission cholinergic GO:0007271 4 0.020
negative regulation of locomotion GO:0040013 18 0.020
single organism organelle organization GO:1902589 199 0.020
response to amine GO:0014075 1 0.020
sodium ion transport GO:0006814 24 0.020
response to organic cyclic compound GO:0014070 51 0.020
positive regulation of gtpase activity GO:0043547 1 0.019
toll like receptor signaling pathway GO:0002224 4 0.019
response to monosaccharide GO:0034284 3 0.019
regulation of sequestering of calcium ion GO:0051282 4 0.019
activation of immune response GO:0002253 9 0.019
regulation of biosynthetic process GO:0009889 250 0.019
Human
lymphocyte proliferation GO:0046651 1 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
Human Mouse
negative regulation of phosphorylation GO:0042326 6 0.019
reproductive process GO:0022414 40 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
sensory perception of pain GO:0019233 1 0.018
regulation of anatomical structure size GO:0090066 33 0.018
Human
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
inorganic ion transmembrane transport GO:0098660 57 0.018
negative regulation of signal transduction GO:0009968 94 0.018
Mouse
immune response GO:0006955 28 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of response to biotic stimulus GO:0002831 2 0.018
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.018
regulation of hydrolase activity GO:0051336 28 0.018
positive regulation of immune response GO:0050778 11 0.017
response to carbohydrate GO:0009743 3 0.017
lipid oxidation GO:0034440 1 0.017
oocyte anterior posterior axis specification GO:0007314 4 0.017
single organism carbohydrate metabolic process GO:0044723 12 0.017
Mouse
iron ion homeostasis GO:0055072 4 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
chordate embryonic development GO:0043009 271 0.017
head development GO:0060322 303 0.017
negative regulation of cell death GO:0060548 60 0.017
Human Mouse
positive regulation of hydrolase activity GO:0051345 13 0.016
cellular amine metabolic process GO:0044106 2 0.016
response to hydrogen peroxide GO:0042542 3 0.016
female sex differentiation GO:0046660 4 0.016
cellular catabolic process GO:0044248 27 0.016
Mouse
amide transport GO:0042886 12 0.016
cellular component morphogenesis GO:0032989 336 0.016
cell killing GO:0001906 2 0.016
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
steroid hormone mediated signaling pathway GO:0043401 9 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
Human
positive regulation of camp metabolic process GO:0030816 2 0.016
synaptic transmission GO:0007268 35 0.016
urogenital system development GO:0001655 97 0.016
positive regulation of developmental process GO:0051094 50 0.015
female gonad development GO:0008585 4 0.015
response to hexose GO:0009746 3 0.015
synaptic vesicle localization GO:0097479 1 0.015
regulation of cardiac muscle contraction GO:0055117 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
Human
regulation of locomotion GO:0040012 55 0.015
fatty acid beta oxidation GO:0006635 1 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
protein localization to plasma membrane GO:0072659 1 0.015
fatty acid biosynthetic process GO:0006633 4 0.015
circulatory system process GO:0003013 87 0.015
Human
negative regulation of protein complex assembly GO:0031333 1 0.015
centrosome cycle GO:0007098 1 0.015
hormone secretion GO:0046879 2 0.015
negative regulation of phosphate metabolic process GO:0045936 13 0.015
positive regulation of catalytic activity GO:0043085 25 0.015
regulation of hormone secretion GO:0046883 2 0.015
response to oxygen containing compound GO:1901700 55 0.015
nucleotide metabolic process GO:0009117 28 0.014
regulation of ion transport GO:0043269 22 0.014
negative regulation of cell motility GO:2000146 17 0.014
organic anion transport GO:0015711 15 0.014
ribonucleotide metabolic process GO:0009259 27 0.014
negative regulation of gene expression GO:0010629 65 0.014
Human
protein localization GO:0008104 40 0.014
cellular response to oxygen levels GO:0071453 1 0.014
neurotransmitter transport GO:0006836 2 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
reactive oxygen species biosynthetic process GO:1903409 1 0.014
negative regulation of rna metabolic process GO:0051253 48 0.014
Human
cellular component biogenesis GO:0044085 178 0.014
sensory perception GO:0007600 39 0.014
intracellular mrna localization GO:0008298 1 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
Mouse
organic substance catabolic process GO:1901575 28 0.014
Mouse
endosomal transport GO:0016197 2 0.014
regulation of growth GO:0040008 42 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
Human
tissue remodeling GO:0048771 4 0.014
protein stabilization GO:0050821 2 0.014
behavior GO:0007610 74 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.013
cellular nitrogen compound catabolic process GO:0044270 15 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
cellular component movement GO:0006928 335 0.013
hydrogen transport GO:0006818 7 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
Human Mouse
organic cyclic compound catabolic process GO:1901361 15 0.013
regulation of blood circulation GO:1903522 32 0.013
axis specification GO:0009798 43 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
single organism cellular localization GO:1902580 46 0.013
pole plasm assembly GO:0007315 4 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
nitrogen compound transport GO:0071705 23 0.013
protein modification process GO:0036211 100 0.013
Mouse
response to lipid GO:0033993 60 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
Mouse
cellular response to radiation GO:0071478 4 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
adult behavior GO:0030534 2 0.012
regulation of jun kinase activity GO:0043506 3 0.012
regulation of phosphorylation GO:0042325 26 0.012
negative regulation of heart contraction GO:0045822 2 0.012
blood vessel development GO:0001568 246 0.012
anterior posterior pattern specification GO:0009952 152 0.012
purine ribonucleoside metabolic process GO:0046128 10 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
hemoglobin biosynthetic process GO:0042541 8 0.012
regulation of collagen metabolic process GO:0010712 2 0.012
regulation of blood pressure GO:0008217 1 0.012
peptidyl serine modification GO:0018209 2 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
metal ion homeostasis GO:0055065 26 0.012
epithelial cell differentiation GO:0030855 116 0.012
cell morphogenesis GO:0000902 289 0.012
vasculature development GO:0001944 278 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
cellular response to oxygen radical GO:0071450 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
regulation of protein metabolic process GO:0051246 56 0.012
Mouse
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
rna localization GO:0006403 4 0.012
negative regulation of molecular function GO:0044092 23 0.012
response to extracellular stimulus GO:0009991 10 0.012
myeloid cell homeostasis GO:0002262 56 0.011
positive regulation of multi organism process GO:0043902 3 0.011
removal of superoxide radicals GO:0019430 2 0.011
aromatic compound catabolic process GO:0019439 15 0.011
apoptotic signaling pathway GO:0097190 23 0.011
Mouse
oligopeptide transport GO:0006857 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
regulation of developmental growth GO:0048638 38 0.011
response to nicotine GO:0035094 2 0.011
calcium mediated signaling GO:0019722 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
digestive tract mesoderm development GO:0007502 1 0.011
oxidoreduction coenzyme metabolic process GO:0006733 1 0.011

gclc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
sensory system disease DOID:0050155 0 0.042
eye and adnexa disease DOID:1492 0 0.042
nervous system disease DOID:863 0 0.042
eye disease DOID:5614 0 0.042
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
organ system cancer DOID:0050686 0 0.012