Danio rerio

0 known processes

psmd11a

proteasome (prosome, macropain) 216S subunit, non-ATPase, 11a

(Aliases: wu:fb44g10,wu:fc16c05,im:7148232)

psmd11a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.513
Human Worm
larval development GO:0002164 2 0.343
Worm
protein metabolic process GO:0019538 183 0.278
Human Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.274
Human Worm
cellular protein catabolic process GO:0044257 4 0.269
Human Worm
aging GO:0007568 2 0.262
Worm
modification dependent macromolecule catabolic process GO:0043632 3 0.246
Human Worm
ubiquitin dependent protein catabolic process GO:0006511 3 0.212
Human Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.182
regulation of cellular biosynthetic process GO:0031326 245 0.175
cellular macromolecule metabolic process GO:0044260 391 0.140
Human Worm
maintenance of location GO:0051235 4 0.139
organic substance biosynthetic process GO:1901576 289 0.128
biosynthetic process GO:0009058 294 0.128
cellular macromolecule biosynthetic process GO:0034645 224 0.125
proteasomal protein catabolic process GO:0010498 2 0.121
regulation of primary metabolic process GO:0080090 311 0.104
cellular protein metabolic process GO:0044267 129 0.101
Human Worm
gene expression GO:0010467 252 0.100
nucleobase containing compound metabolic process GO:0006139 274 0.092
signal transduction GO:0007165 455 0.088
protein modification process GO:0036211 100 0.082
regulation of metabolic process GO:0019222 359 0.079
mitochondrion organization GO:0007005 4 0.079
response to stress GO:0006950 263 0.076
Worm
negative regulation of biological process GO:0048519 304 0.072
macromolecule biosynthetic process GO:0009059 227 0.069
positive regulation of cell cycle GO:0045787 3 0.068
regulation of gene expression GO:0010468 265 0.067
rna metabolic process GO:0016070 219 0.067
embryo development ending in birth or egg hatching GO:0009792 271 0.066
Worm
cellular protein modification process GO:0006464 100 0.064
regulation of multicellular organism growth GO:0040014 4 0.063
regulation of biosynthetic process GO:0009889 250 0.061
macromolecule modification GO:0043412 111 0.061
heterocycle biosynthetic process GO:0018130 215 0.060
ribonucleoside monophosphate catabolic process GO:0009158 4 0.060
programmed cell death GO:0012501 119 0.057
Worm
nucleoside monophosphate catabolic process GO:0009125 4 0.055
lipid storage GO:0019915 1 0.054
cellular component morphogenesis GO:0032989 336 0.053
regulation of protein catabolic process GO:0042176 1 0.052
single organism metabolic process GO:0044710 217 0.052
organelle organization GO:0006996 227 0.050
multicellular organism growth GO:0035264 4 0.050
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.049
negative regulation of signal transduction GO:0009968 94 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.047
regulation of cell death GO:0010941 103 0.047
death GO:0016265 121 0.046
Worm
protein localization to plasma membrane GO:0072659 1 0.045
cellular biosynthetic process GO:0044249 286 0.043
positive regulation of biological process GO:0048518 253 0.043
cellular nitrogen compound metabolic process GO:0034641 290 0.043
lateral inhibition GO:0046331 1 0.042
nitrogen compound metabolic process GO:0006807 319 0.042
regulation of programmed cell death GO:0043067 101 0.042
rna biosynthetic process GO:0032774 181 0.041
aromatic compound biosynthetic process GO:0019438 217 0.041
regulation of protein ubiquitination GO:0031396 3 0.041
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.041
cell cycle g1 s phase transition GO:0044843 1 0.040
organic cyclic compound biosynthetic process GO:1901362 223 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.040
organic substance catabolic process GO:1901575 28 0.040
Human Worm
proteolysis GO:0006508 38 0.040
Human Worm Fly
negative regulation of cell communication GO:0010648 96 0.039
regulation of cellular metabolic process GO:0031323 320 0.039
microtubule organizing center organization GO:0031023 1 0.038
regulation of rna metabolic process GO:0051252 224 0.038
generation of neurons GO:0048699 385 0.037
cellular component assembly GO:0022607 170 0.037
Human Worm
organic cyclic compound metabolic process GO:1901360 301 0.036
nucleic acid metabolic process GO:0090304 244 0.036
regulation of response to stimulus GO:0048583 269 0.035
g1 s transition of mitotic cell cycle GO:0000082 1 0.035
cell death GO:0008219 121 0.035
Worm
regulation of nucleocytoplasmic transport GO:0046822 2 0.034
meiotic nuclear division GO:0007126 4 0.034
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
locomotion GO:0040011 313 0.033
regulation of cell communication GO:0010646 232 0.032
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.032
specification of symmetry GO:0009799 204 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
membrane fusion GO:0061025 2 0.031
protein polyubiquitination GO:0000209 4 0.031
negative regulation of multicellular organismal process GO:0051241 69 0.030
single fertilization GO:0007338 3 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
mitotic cell cycle GO:0000278 64 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
positive regulation of protein complex assembly GO:0031334 2 0.030
transcription dna templated GO:0006351 181 0.029
negative regulation of protein transport GO:0051224 3 0.029
positive regulation of catabolic process GO:0009896 4 0.029
autophagy GO:0006914 4 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
negative regulation of cytoplasmic transport GO:1903650 2 0.029
cytokinesis GO:0000910 3 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
neuron development GO:0048666 262 0.028
developmental growth GO:0048589 166 0.028
neuron projection morphogenesis GO:0048812 161 0.028
compound eye development GO:0048749 2 0.028
cell part morphogenesis GO:0032990 246 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
negative regulation of signaling GO:0023057 96 0.027
single organism transport GO:0044765 206 0.026
positive regulation of metabolic process GO:0009893 108 0.026
determination of bilateral symmetry GO:0009855 204 0.026
response to chemical GO:0042221 320 0.026
regulation of protein transport GO:0051223 3 0.026
apoptotic process GO:0006915 116 0.026
Worm
purine nucleoside monophosphate catabolic process GO:0009128 4 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
regulation of establishment of protein localization GO:0070201 4 0.025
cell morphogenesis GO:0000902 289 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
reproduction GO:0000003 40 0.025
Worm
regulation of apoptotic process GO:0042981 98 0.025
negative regulation of intracellular protein transport GO:0090317 3 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
single organism membrane fusion GO:0044801 2 0.024
neuron differentiation GO:0030182 353 0.024
protein dephosphorylation GO:0006470 3 0.024
regionalization GO:0003002 274 0.024
establishment of localization in cell GO:0051649 77 0.024
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.023
negative regulation of mitosis GO:0045839 3 0.023
gtp metabolic process GO:0046039 4 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
regulation of cell shape GO:0008360 1 0.023
response to topologically incorrect protein GO:0035966 2 0.023
macromolecular complex disassembly GO:0032984 1 0.022
cellular component movement GO:0006928 335 0.022
cellular component disassembly GO:0022411 1 0.022
determination of left right symmetry GO:0007368 179 0.022
rna modification GO:0009451 2 0.022
stem cell division GO:0017145 1 0.022
spindle assembly GO:0051225 2 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
peptidyl lysine acetylation GO:0018394 2 0.021
regulation of biological quality GO:0065008 263 0.021
regulation of protein complex assembly GO:0043254 3 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
regulation of gtp catabolic process GO:0033124 2 0.021
cell projection morphogenesis GO:0048858 244 0.021
catabolic process GO:0009056 32 0.021
Human Worm
regulation of nucleoside metabolic process GO:0009118 2 0.021
regulation of transcription dna templated GO:0006355 213 0.021
protein acetylation GO:0006473 2 0.020
regulation of cytokine production GO:0001817 3 0.020
negative regulation of nuclear division GO:0051784 3 0.020
taxis GO:0042330 109 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.020
regulation of locomotion GO:0040012 55 0.020
protein k63 linked ubiquitination GO:0070534 2 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
eye development GO:0001654 277 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
sensory organ development GO:0007423 393 0.020
atp catabolic process GO:0006200 4 0.020
cytoskeleton organization GO:0007010 96 0.020
dna templated transcription initiation GO:0006352 1 0.019
regulation of cellular protein catabolic process GO:1903362 1 0.019
organic acid metabolic process GO:0006082 31 0.019
localization within membrane GO:0051668 1 0.019
carbohydrate homeostasis GO:0033500 1 0.019
regulation of stem cell differentiation GO:2000736 4 0.019
protein n linked glycosylation GO:0006487 1 0.019
cell cycle process GO:0022402 53 0.019
negative regulation of cellular process GO:0048523 283 0.019
positive regulation of cellular process GO:0048522 201 0.019
response to monosaccharide GO:0034284 3 0.019
growth GO:0040007 174 0.019
regulation of synapse organization GO:0050807 3 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of chromosome segregation GO:0051983 1 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
cellular ketone metabolic process GO:0042180 11 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
vasculature development GO:0001944 278 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
gtp catabolic process GO:0006184 2 0.017
synaptic vesicle localization GO:0097479 1 0.017
protein polymerization GO:0051258 4 0.017
meiosis i GO:0007127 1 0.017
response to glucose GO:0009749 3 0.017
regulation of cell activation GO:0050865 1 0.017
homeostatic process GO:0042592 142 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of developmental process GO:0050793 247 0.017
cell motility GO:0048870 244 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
heterocycle metabolic process GO:0046483 290 0.017
cell projection organization GO:0030030 284 0.017
positive regulation of transport GO:0051050 2 0.017
neuron projection development GO:0031175 180 0.017
oxoacid metabolic process GO:0043436 31 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
regulation of mrna processing GO:0050684 3 0.017
mitochondrial transport GO:0006839 2 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
phosphorus metabolic process GO:0006793 109 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
single organism localization GO:1902578 225 0.017
protein modification by small protein conjugation or removal GO:0070647 14 0.016
response to external stimulus GO:0009605 264 0.016
protein complex disassembly GO:0043241 1 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
centrosome organization GO:0051297 1 0.016
stem cell maintenance GO:0019827 4 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
nucleic acid templated transcription GO:0097659 181 0.016
cellular response to nutrient levels GO:0031669 2 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
cellular amine metabolic process GO:0044106 2 0.016
cellular macromolecular complex assembly GO:0034622 24 0.015
Human Worm
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
sister chromatid cohesion GO:0007062 2 0.015
cellular catabolic process GO:0044248 27 0.015
Human Worm
response to wounding GO:0009611 116 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
amine metabolic process GO:0009308 2 0.015
organism emergence from protective structure GO:0071684 4 0.015
response to abiotic stimulus GO:0009628 122 0.015
regulation of cell differentiation GO:0045595 142 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of autophagy GO:0010506 3 0.015
protein acylation GO:0043543 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
regulation of protein metabolic process GO:0051246 56 0.015
regulation of localization GO:0032879 104 0.015
germ line stem cell maintenance GO:0030718 2 0.014
single organism biosynthetic process GO:0044711 71 0.014
response to drug GO:0042493 3 0.014
rna localization GO:0006403 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
brain development GO:0007420 293 0.014
axon development GO:0061564 166 0.014
somatic muscle development GO:0007525 4 0.014
synaptic vesicle transport GO:0048489 1 0.014
protein secretion GO:0009306 1 0.014
cellular response to organic substance GO:0071310 105 0.014
negative regulation of response to dna damage stimulus GO:2001021 3 0.014
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.014
organelle assembly GO:0070925 110 0.014
transport GO:0006810 220 0.014
protein catabolic process GO:0030163 7 0.014
Human Worm
protein complex localization GO:0031503 1 0.014
regulation of gtpase activity GO:0043087 2 0.013
protein modification by small protein removal GO:0070646 1 0.013
rna export from nucleus GO:0006405 1 0.013
cranial nerve morphogenesis GO:0021602 15 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
fertilization GO:0009566 3 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
response to corticosteroid GO:0031960 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
establishment of rna localization GO:0051236 3 0.013
regulation of cell development GO:0060284 100 0.013
regulation of hormone secretion GO:0046883 2 0.013
wound healing GO:0042060 90 0.013
protein import GO:0017038 3 0.013
nuclear transport GO:0051169 4 0.013
cellular response to starvation GO:0009267 1 0.013
positive regulation of secretion GO:0051047 1 0.013
negative regulation of developmental process GO:0051093 65 0.013
chordate embryonic development GO:0043009 271 0.013
lipid homeostasis GO:0055088 3 0.013
regulation of inflammatory response GO:0050727 2 0.013
mrna export from nucleus GO:0006406 1 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
regulation of reproductive process GO:2000241 4 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.012
response to hexose GO:0009746 3 0.012
female sex differentiation GO:0046660 4 0.012
translational initiation GO:0006413 3 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
nuclear export GO:0051168 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
peptide transport GO:0015833 1 0.012
tissue remodeling GO:0048771 4 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
regulation of protein localization to plasma membrane GO:1903076 1 0.012
blood vessel development GO:0001568 246 0.012
exocytosis GO:0006887 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
optic nerve morphogenesis GO:0021631 6 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
chemotaxis GO:0006935 104 0.012
glial cell migration GO:0008347 3 0.012
pole plasm assembly GO:0007315 4 0.012
cellular component biogenesis GO:0044085 178 0.012
Human Worm
ovulation cycle GO:0042698 2 0.012
cell substrate adhesion GO:0031589 4 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of synapse assembly GO:0051963 3 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
single organism organelle organization GO:1902589 199 0.012
organelle fusion GO:0048284 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.012
ras protein signal transduction GO:0007265 7 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.011
microtubule based process GO:0007017 60 0.011
regulation of molecular function GO:0065009 70 0.011
cell migration GO:0016477 237 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
small molecule metabolic process GO:0044281 77 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of transport GO:0051049 45 0.011
adult behavior GO:0030534 2 0.011
hatching GO:0035188 4 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
apoptotic signaling pathway GO:0097190 23 0.011
regulation of translational initiation GO:0006446 1 0.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.011
male meiosis GO:0007140 2 0.011
phagocytosis GO:0006909 3 0.011
defense response GO:0006952 47 0.011
female gonad development GO:0008585 4 0.011
multi organism process GO:0051704 134 0.011
cellular macromolecule catabolic process GO:0044265 12 0.011
Human Worm
macromolecular complex subunit organization GO:0043933 74 0.011
Human Worm
response to glucocorticoid GO:0051384 1 0.011
glucose homeostasis GO:0042593 1 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
tissue regeneration GO:0042246 74 0.011
regulation of glial cell differentiation GO:0045685 4 0.010
locomotor rhythm GO:0045475 3 0.010
response to organic substance GO:0010033 153 0.010
cellular protein complex assembly GO:0043623 19 0.010
Human Worm
localization of cell GO:0051674 244 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
protein k48 linked ubiquitination GO:0070936 1 0.010
central nervous system development GO:0007417 387 0.010
regulation of protein targeting GO:1903533 2 0.010
muscle cell differentiation GO:0042692 139 0.010
establishment of localization GO:0051234 244 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
angiogenesis GO:0001525 158 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
cell matrix adhesion GO:0007160 4 0.010
cellular response to external stimulus GO:0071496 2 0.010
cell cycle GO:0007049 93 0.010
regulation of cellular component organization GO:0051128 86 0.010
regulation of mitochondrion organization GO:0010821 1 0.010
cellular response to stress GO:0033554 62 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010

psmd11a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of metabolism DOID:0014667 0 0.017