Danio rerio

0 known processes

mus81

MUS81 endonuclease homolog (yeast)

(Aliases: wu:fc26g01,zgc:91801,zgc:66489)

mus81 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via homologous recombination GO:0000724 1 0.327
meiotic nuclear division GO:0007126 4 0.308
recombinational repair GO:0000725 1 0.212
double strand break repair GO:0006302 3 0.200
cellular nitrogen compound metabolic process GO:0034641 290 0.195
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.171
cellular macromolecule metabolic process GO:0044260 391 0.169
telomere organization GO:0032200 1 0.127
organic cyclic compound metabolic process GO:1901360 301 0.124
positive regulation of cell cycle GO:0045787 3 0.122
meiosis i GO:0007127 1 0.117
spindle assembly involved in mitosis GO:0090307 1 0.114
female meiotic division GO:0007143 2 0.105
peptidyl serine phosphorylation GO:0018105 1 0.103
ribonucleoside monophosphate catabolic process GO:0009158 4 0.099
microtubule organizing center organization GO:0031023 1 0.097
meiotic cell cycle process GO:1903046 3 0.096
spindle assembly GO:0051225 2 0.094
positive regulation of dna metabolic process GO:0051054 1 0.091
organism emergence from protective structure GO:0071684 4 0.083
small molecule metabolic process GO:0044281 77 0.079
cell cycle g2 m phase transition GO:0044839 4 0.078
nitrogen compound metabolic process GO:0006807 319 0.073
nucleoside monophosphate catabolic process GO:0009125 4 0.071
purine nucleoside monophosphate catabolic process GO:0009128 4 0.070
chromosome organization GO:0051276 31 0.070
atp catabolic process GO:0006200 4 0.070
phosphorus metabolic process GO:0006793 109 0.068
regulation of nitrogen compound metabolic process GO:0051171 251 0.066
nucleic acid metabolic process GO:0090304 244 0.063
meiotic chromosome segregation GO:0045132 3 0.059
heterocycle metabolic process GO:0046483 290 0.059
signal transduction GO:0007165 455 0.058
male meiosis GO:0007140 2 0.057
atp metabolic process GO:0046034 5 0.057
single organism metabolic process GO:0044710 217 0.056
dna catabolic process GO:0006308 1 0.056
positive regulation of catabolic process GO:0009896 4 0.054
organonitrogen compound metabolic process GO:1901564 74 0.054
cellular aromatic compound metabolic process GO:0006725 295 0.053
positive regulation of cellular component biogenesis GO:0044089 3 0.051
nucleic acid templated transcription GO:0097659 181 0.050
telomere maintenance GO:0000723 1 0.050
positive regulation of cellular catabolic process GO:0031331 3 0.049
g2 m transition of mitotic cell cycle GO:0000086 4 0.049
larval development GO:0002164 2 0.048
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.048
macromolecule biosynthetic process GO:0009059 227 0.046
response to stress GO:0006950 263 0.045
negative regulation of nuclear division GO:0051784 3 0.045
reciprocal dna recombination GO:0035825 1 0.045
positive regulation of biological process GO:0048518 253 0.044
mitotic recombination GO:0006312 2 0.044
negative regulation of mitosis GO:0045839 3 0.043
specification of axis polarity GO:0065001 4 0.042
maintenance of location GO:0051235 4 0.042
mitotic cell cycle embryonic GO:0045448 2 0.040
nucleobase containing compound metabolic process GO:0006139 274 0.038
regulation of microtubule cytoskeleton organization GO:0070507 3 0.037
regulation of response to stimulus GO:0048583 269 0.036
organelle organization GO:0006996 227 0.036
aromatic compound biosynthetic process GO:0019438 217 0.036
regulation of biological quality GO:0065008 263 0.035
oocyte maturation GO:0001556 4 0.034
regulation of protein complex assembly GO:0043254 3 0.034
regulation of signal transduction GO:0009966 225 0.034
positive regulation of cellular process GO:0048522 201 0.033
regulation of chromosome segregation GO:0051983 1 0.033
purine ribonucleotide metabolic process GO:0009150 27 0.033
cellular response to dna damage stimulus GO:0006974 24 0.033
cell surface receptor signaling pathway GO:0007166 325 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
phosphate containing compound metabolic process GO:0006796 108 0.030
positive regulation of protein complex assembly GO:0031334 2 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
carboxylic acid metabolic process GO:0019752 22 0.030
regulation of binding GO:0051098 3 0.029
organic acid metabolic process GO:0006082 31 0.029
response to chemical GO:0042221 320 0.028
negative regulation of biological process GO:0048519 304 0.026
cellular biosynthetic process GO:0044249 286 0.026
centrosome cycle GO:0007098 1 0.026
cell cycle GO:0007049 93 0.026
mitotic nuclear division GO:0007067 18 0.026
nucleotide metabolic process GO:0009117 28 0.026
organic substance biosynthetic process GO:1901576 289 0.025
cellular component biogenesis GO:0044085 178 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
regulation of signaling GO:0023051 235 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
single organism organelle organization GO:1902589 199 0.024
peptidyl serine modification GO:0018209 2 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
response to drug GO:0042493 3 0.024
organelle fission GO:0048285 23 0.024
b cell activation GO:0042113 2 0.024
amine metabolic process GO:0009308 2 0.022
cell cycle arrest GO:0007050 1 0.022
lipid storage GO:0019915 1 0.022
ribose phosphate metabolic process GO:0019693 27 0.022
gtp catabolic process GO:0006184 2 0.022
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
aging GO:0007568 2 0.021
protein modification process GO:0036211 100 0.021
regulation of gene expression GO:0010468 265 0.021
regulation of cellular metabolic process GO:0031323 320 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
cellular component assembly GO:0022607 170 0.020
female gonad development GO:0008585 4 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
protein complex subunit organization GO:0071822 46 0.019
cellular amine metabolic process GO:0044106 2 0.019
oxoacid metabolic process GO:0043436 31 0.019
cellular response to radiation GO:0071478 4 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
developmental growth GO:0048589 166 0.019
purine nucleotide metabolic process GO:0006163 27 0.019
immunoglobulin mediated immune response GO:0016064 3 0.018
negative regulation of cellular process GO:0048523 283 0.018
cytokinesis GO:0000910 3 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
reciprocal meiotic recombination GO:0007131 1 0.018
regulation of cellular component organization GO:0051128 86 0.018
rna localization GO:0006403 4 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
nucleoside phosphate metabolic process GO:0006753 28 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
ribonucleotide metabolic process GO:0009259 27 0.018
cell cycle process GO:0022402 53 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
regulation of gene silencing GO:0060968 1 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
spermatid development GO:0007286 2 0.017
multicellular organism growth GO:0035264 4 0.017
regulation of cell cycle GO:0051726 52 0.017
response to organic substance GO:0010033 153 0.017
central nervous system development GO:0007417 387 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
microtubule based process GO:0007017 60 0.016
cell migration GO:0016477 237 0.016
cellular component morphogenesis GO:0032989 336 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
somatic cell dna recombination GO:0016444 1 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
cell motility GO:0048870 244 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
gene expression GO:0010467 252 0.015
protein metabolic process GO:0019538 183 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
negative regulation of signal transduction GO:0009968 94 0.015
dna recombination GO:0006310 5 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
negative regulation of nucleic acid templated transcription GO:1903507 45 0.015
purine containing compound metabolic process GO:0072521 29 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
cellular ketone metabolic process GO:0042180 11 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
specification of symmetry GO:0009799 204 0.015
cellular response to stress GO:0033554 62 0.015
cellular protein metabolic process GO:0044267 129 0.015
guanosine containing compound metabolic process GO:1901068 4 0.014
regulation of molecular function GO:0065009 70 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
hatching GO:0035188 4 0.014
centrosome organization GO:0051297 1 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
ras protein signal transduction GO:0007265 7 0.014
transcription dna templated GO:0006351 181 0.014
wnt signaling pathway GO:0016055 80 0.014
spermatid differentiation GO:0048515 2 0.014
cell substrate adhesion GO:0031589 4 0.013
immune system process GO:0002376 241 0.013
homologous chromosome segregation GO:0045143 1 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
cellular nitrogen compound catabolic process GO:0044270 15 0.013
organelle assembly GO:0070925 110 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
regionalization GO:0003002 274 0.013
intracellular mrna localization GO:0008298 1 0.013
female sex differentiation GO:0046660 4 0.013
mitotic cell cycle GO:0000278 64 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
biosynthetic process GO:0009058 294 0.013
negative regulation of response to stimulus GO:0048585 104 0.012
response to uv GO:0009411 3 0.012
regulation of cell communication GO:0010646 232 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.012
sister chromatid segregation GO:0000819 6 0.012
rna biosynthetic process GO:0032774 181 0.012
cell morphogenesis GO:0000902 289 0.012
dna metabolic process GO:0006259 27 0.012
macromolecule modification GO:0043412 111 0.012
cleavage furrow formation GO:0036089 2 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
digestive tract morphogenesis GO:0048546 231 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
cellular localization GO:0051641 97 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
b cell mediated immunity GO:0019724 3 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
mitotic cell cycle process GO:1903047 48 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
growth GO:0040007 174 0.012
intracellular signal transduction GO:0035556 85 0.012
protein polymerization GO:0051258 4 0.011
homeostatic process GO:0042592 142 0.011
macromolecule localization GO:0033036 54 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
immune system development GO:0002520 191 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
regulation of gtpase activity GO:0043087 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
head development GO:0060322 303 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
positive regulation of jun kinase activity GO:0043507 2 0.011
regulation of transcription dna templated GO:0006355 213 0.011
gtp metabolic process GO:0046039 4 0.011
regulation of dna recombination GO:0000018 2 0.011
leukocyte proliferation GO:0070661 1 0.011
cellular protein modification process GO:0006464 100 0.011
regulation of cell activation GO:0050865 1 0.011
tube morphogenesis GO:0035239 349 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.010
digestive system development GO:0055123 289 0.010
positive regulation of cell activation GO:0050867 1 0.010
regulation of cell maturation GO:1903429 1 0.010
positive regulation of nuclease activity GO:0032075 1 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
nuclear division GO:0000280 23 0.010
neuron development GO:0048666 262 0.010
cellular component disassembly GO:0022411 1 0.010
regulation of protein catabolic process GO:0042176 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
nucleobase containing compound catabolic process GO:0034655 15 0.010
regulation of organelle assembly GO:1902115 4 0.010
gastrulation GO:0007369 208 0.010
establishment of rna localization GO:0051236 3 0.010
regulation of metabolic process GO:0019222 359 0.010
mitotic cytokinesis GO:0000281 3 0.010

mus81 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.050
disease of cellular proliferation DOID:14566 0 0.050
thoracic cancer DOID:5093 0 0.040
organ system cancer DOID:0050686 0 0.040
breast cancer DOID:1612 0 0.029
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.011