Danio rerio

0 known processes

ext1a

exostoses (multiple) 1a

(Aliases: wu:fd07d06,fd07d06)

ext1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.571
Mouse
determination of bilateral symmetry GO:0009855 204 0.549
renal system development GO:0072001 94 0.445
cell projection organization GO:0030030 284 0.441
Zebrafish Mouse Fly
cellular component morphogenesis GO:0032989 336 0.390
Zebrafish Mouse Fly
signal transduction GO:0007165 455 0.390
Zebrafish Fly
convergent extension involved in gastrulation GO:0060027 71 0.363
digestive system development GO:0055123 289 0.316
Mouse Worm
regulation of multicellular organismal development GO:2000026 223 0.316
Zebrafish
convergent extension GO:0060026 118 0.311
neuron development GO:0048666 262 0.305
Zebrafish Mouse Fly
cell cell recognition GO:0009988 1 0.290
blood vessel development GO:0001568 246 0.258
wnt signaling pathway GO:0016055 80 0.254
Fly
determination of heart left right asymmetry GO:0061371 117 0.243
regulation of multicellular organismal process GO:0051239 277 0.234
Zebrafish
heart development GO:0007507 313 0.228
regulation of synapse organization GO:0050807 3 0.216
cell migration GO:0016477 237 0.215
Fly
negative regulation of response to stimulus GO:0048585 104 0.215
growth GO:0040007 174 0.214
Zebrafish
tube closure GO:0060606 1 0.206
larval development GO:0002164 2 0.204
regulation of cell communication GO:0010646 232 0.202
Zebrafish Fly
oocyte maturation GO:0001556 4 0.201
generation of neurons GO:0048699 385 0.201
Zebrafish Mouse Fly
localization of cell GO:0051674 244 0.200
Fly
stem cell maintenance GO:0019827 4 0.193
cellular component movement GO:0006928 335 0.193
Zebrafish Mouse Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.192
regulation of signal transduction GO:0009966 225 0.187
Zebrafish Fly
regulation of biological quality GO:0065008 263 0.170
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.169
Zebrafish Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.169
mesoderm development GO:0007498 88 0.166
Mouse
urogenital system development GO:0001655 97 0.165
multicellular organism growth GO:0035264 4 0.165
determination of left right symmetry GO:0007368 179 0.161
protein modification process GO:0036211 100 0.160
negative regulation of signal transduction GO:0009968 94 0.160
regulation of signaling GO:0023051 235 0.157
Zebrafish Fly
negative chemotaxis GO:0050919 1 0.154
locomotion GO:0040011 313 0.154
Zebrafish Mouse Fly
camera type eye development GO:0043010 222 0.152
cell projection morphogenesis GO:0048858 244 0.151
Zebrafish Mouse Fly
axon development GO:0061564 166 0.150
Zebrafish Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.147
Fly
embryonic heart tube development GO:0035050 133 0.146
embryonic heart tube morphogenesis GO:0003143 108 0.144
regulation of reproductive process GO:2000241 4 0.140
axonogenesis GO:0007409 152 0.139
Zebrafish Mouse Fly
negative regulation of protein phosphorylation GO:0001933 4 0.137
digestive tract morphogenesis GO:0048546 231 0.136
Mouse
regulation of developmental process GO:0050793 247 0.136
Zebrafish
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.134
neuron differentiation GO:0030182 353 0.127
Zebrafish Mouse Fly
gastrulation GO:0007369 208 0.124
Mouse
heart morphogenesis GO:0003007 156 0.123
regulation of multicellular organism growth GO:0040014 4 0.117
axis specification GO:0009798 43 0.116
regulation of erk1 and erk2 cascade GO:0070372 4 0.114
negative regulation of biological process GO:0048519 304 0.114
liver development GO:0001889 96 0.114
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.113
embryonic organ morphogenesis GO:0048562 274 0.112
heart looping GO:0001947 94 0.112
single organism metabolic process GO:0044710 217 0.110
Human Zebrafish Mouse Worm Fly
dorsal ventral pattern formation GO:0009953 125 0.110
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.105
morphogenesis of an epithelium GO:0002009 333 0.102
cellular protein modification process GO:0006464 100 0.101
regulation of stem cell differentiation GO:2000736 4 0.101
axon guidance GO:0007411 86 0.100
Zebrafish Mouse Fly
primary neural tube formation GO:0014020 1 0.100
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.100
Fly
cell migration involved in gastrulation GO:0042074 79 0.099
cell part morphogenesis GO:0032990 246 0.098
Zebrafish Mouse Fly
rhombomere boundary formation GO:0021654 10 0.097
response to chemical GO:0042221 320 0.097
Zebrafish Mouse Fly
negative regulation of neuron projection regeneration GO:0070571 4 0.096
regulation of canonical wnt signaling pathway GO:0060828 34 0.095
regulation of rna biosynthetic process GO:2001141 213 0.094
kidney development GO:0001822 92 0.093
regulation of primary metabolic process GO:0080090 311 0.090
sensory organ development GO:0007423 393 0.089
regulation of anatomical structure morphogenesis GO:0022603 130 0.089
Zebrafish
cellular biosynthetic process GO:0044249 286 0.087
Human Zebrafish Mouse Worm Fly
synaptic target recognition GO:0008039 1 0.087
regulation of synapse assembly GO:0051963 3 0.086
phosphorus metabolic process GO:0006793 109 0.086
hepaticobiliary system development GO:0061008 98 0.086
establishment of protein localization to organelle GO:0072594 4 0.084
eye morphogenesis GO:0048592 144 0.083
cell motility GO:0048870 244 0.083
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.083
neuron projection extension GO:1990138 45 0.082
Zebrafish
negative regulation of wnt signaling pathway GO:0030178 30 0.081
transport GO:0006810 220 0.080
Fly
protein metabolic process GO:0019538 183 0.080
Human Zebrafish Mouse Worm Fly
epithelial tube formation GO:0072175 19 0.080
sexual reproduction GO:0019953 36 0.080
Fly
mesodermal cell fate specification GO:0007501 12 0.079
positive regulation of biological process GO:0048518 253 0.079
Zebrafish
neuron projection development GO:0031175 180 0.078
Zebrafish Mouse Fly
sensory organ morphogenesis GO:0090596 200 0.078
muscle tissue development GO:0060537 110 0.078
brain development GO:0007420 293 0.077
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.077
Zebrafish Mouse Fly
specification of symmetry GO:0009799 204 0.076
regulation of cellular metabolic process GO:0031323 320 0.075
cell morphogenesis GO:0000902 289 0.075
Zebrafish Mouse Fly
gene expression GO:0010467 252 0.075
regulation of growth GO:0040008 42 0.074
Zebrafish
negative regulation of collateral sprouting GO:0048671 2 0.074
cell surface receptor signaling pathway GO:0007166 325 0.073
Zebrafish Fly
digestive tract development GO:0048565 265 0.073
Mouse Worm
formation of primary germ layer GO:0001704 62 0.073
regulation of cellular component organization GO:0051128 86 0.072
Zebrafish
erk1 and erk2 cascade GO:0070371 4 0.071
positive regulation of stress activated mapk cascade GO:0032874 3 0.071
vasculature development GO:0001944 278 0.070
chemotaxis GO:0006935 104 0.069
Zebrafish Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.069
protein phosphorylation GO:0006468 47 0.068
embryonic organ development GO:0048568 381 0.068
taxis GO:0042330 109 0.068
Zebrafish Mouse Fly
negative regulation of stem cell differentiation GO:2000737 2 0.067
rna biosynthetic process GO:0032774 181 0.067
regulation of cell differentiation GO:0045595 142 0.066
Zebrafish
female sex differentiation GO:0046660 4 0.065
cellular protein metabolic process GO:0044267 129 0.064
regeneration GO:0031099 91 0.064
cellular aromatic compound metabolic process GO:0006725 295 0.063
single organism transport GO:0044765 206 0.063
Fly
regulation of wound healing GO:0061041 2 0.063
regulation of neurogenesis GO:0050767 87 0.062
Zebrafish
developmental growth GO:0048589 166 0.062
Zebrafish
response to fluid shear stress GO:0034405 2 0.062
retina development in camera type eye GO:0060041 146 0.062
adherens junction organization GO:0034332 4 0.060
biosynthetic process GO:0009058 294 0.059
Human Zebrafish Mouse Worm Fly
muscle structure development GO:0061061 196 0.059
negative regulation of cell communication GO:0010648 96 0.059
phosphorylation GO:0016310 69 0.059
developmental process involved in reproduction GO:0003006 27 0.058
positive regulation of synapse assembly GO:0051965 1 0.057
regulation of wnt signaling pathway GO:0030111 53 0.056
protein localization to nucleus GO:0034504 3 0.056
blood vessel morphogenesis GO:0048514 216 0.055
negative regulation of cellular process GO:0048523 283 0.055
negative regulation of map kinase activity GO:0043407 2 0.055
response to stress GO:0006950 263 0.055
head development GO:0060322 303 0.055
Mouse
single organism organelle organization GO:1902589 199 0.055
Fly
response to external stimulus GO:0009605 264 0.055
Zebrafish Mouse Fly
neural tube development GO:0021915 62 0.055
mesoderm formation GO:0001707 43 0.055
organic cyclic compound metabolic process GO:1901360 301 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.054
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.054
Zebrafish
female gonad development GO:0008585 4 0.054
gland development GO:0048732 143 0.054
regulation of epithelial cell proliferation GO:0050678 3 0.053
regulation of response to stimulus GO:0048583 269 0.053
Zebrafish Fly
rna metabolic process GO:0016070 219 0.052
multicellular organism reproduction GO:0032504 35 0.052
Fly
heart jogging GO:0003146 40 0.052
small molecule metabolic process GO:0044281 77 0.051
Human Zebrafish Mouse Worm Fly
connective tissue development GO:0061448 99 0.051
Zebrafish
transcription dna templated GO:0006351 181 0.051
neuromuscular synaptic transmission GO:0007274 2 0.051
regulation of myotube differentiation GO:0010830 2 0.050
embryonic skeletal system morphogenesis GO:0048704 93 0.050
reproductive process GO:0022414 40 0.048
Fly
regulation of biosynthetic process GO:0009889 250 0.048
cellular response to external stimulus GO:0071496 2 0.048
macromolecule biosynthetic process GO:0009059 227 0.047
Human Zebrafish Mouse Worm Fly
inner ear development GO:0048839 126 0.047
organelle organization GO:0006996 227 0.047
Fly
cellular amine metabolic process GO:0044106 2 0.047
regulation of protein catabolic process GO:0042176 1 0.047
regulation of macromolecule metabolic process GO:0060255 317 0.047
cellular response to retinoic acid GO:0071300 1 0.046
forebrain development GO:0030900 96 0.045
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.045
organonitrogen compound biosynthetic process GO:1901566 47 0.044
Human Zebrafish Fly
regulation of cell development GO:0060284 100 0.044
Zebrafish
bmp signaling pathway GO:0030509 52 0.044
regulation of axonogenesis GO:0050770 32 0.044
Zebrafish
heterocycle metabolic process GO:0046483 290 0.044
intracellular signal transduction GO:0035556 85 0.043
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.043
tissue regeneration GO:0042246 74 0.043
neuron projection guidance GO:0097485 86 0.043
Zebrafish Mouse Fly
cellular protein catabolic process GO:0044257 4 0.043
forebrain anterior posterior pattern specification GO:0021797 3 0.042
death GO:0016265 121 0.042
negative regulation of gliogenesis GO:0014014 1 0.042
macromolecule modification GO:0043412 111 0.042
astrocyte differentiation GO:0048708 1 0.042
cell matrix adhesion GO:0007160 4 0.041
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.041
retina morphogenesis in camera type eye GO:0060042 79 0.041
determination of ventral identity GO:0048264 21 0.041
regulation of embryonic development GO:0045995 47 0.041
regulation of locomotion GO:0040012 55 0.040
negative regulation of axon regeneration GO:0048681 4 0.039
phosphate containing compound metabolic process GO:0006796 108 0.039
lipid storage GO:0019915 1 0.039
anterior posterior pattern specification GO:0009952 152 0.039
mesoderm morphogenesis GO:0048332 51 0.039
regulation of protein metabolic process GO:0051246 56 0.038
positive regulation of cellular process GO:0048522 201 0.038
Zebrafish
ameboidal type cell migration GO:0001667 143 0.038
multicellular organismal reproductive process GO:0048609 35 0.038
Fly
centrosome organization GO:0051297 1 0.038
negative regulation of multicellular organismal process GO:0051241 69 0.037
diencephalon development GO:0021536 58 0.037
morphogenesis of embryonic epithelium GO:0016331 30 0.037
negative regulation of signaling GO:0023057 96 0.037
regulation of metabolic process GO:0019222 359 0.037
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.036
hormone transport GO:0009914 2 0.036
response to carbohydrate GO:0009743 3 0.036
dna templated transcription initiation GO:0006352 1 0.036
negative regulation of mapk cascade GO:0043409 4 0.035
single organism localization GO:1902578 225 0.035
Fly
modification dependent protein catabolic process GO:0019941 3 0.035
regulation of tube size GO:0035150 2 0.035
regulation of macromolecule biosynthetic process GO:0010556 225 0.035
skeletal system development GO:0001501 181 0.035
Zebrafish Mouse
negative regulation of catabolic process GO:0009895 3 0.035
nerve development GO:0021675 45 0.034
regulation of circadian rhythm GO:0042752 4 0.034
positive regulation of cell adhesion GO:0045785 1 0.034
motor neuron axon guidance GO:0008045 23 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.034
Zebrafish Fly
response to organic substance GO:0010033 153 0.034
Zebrafish
negative regulation of gene expression GO:0010629 65 0.034
regulation of mesoderm development GO:2000380 11 0.034
nuclear transport GO:0051169 4 0.033
regulation of establishment of planar polarity GO:0090175 4 0.033
synapse organization GO:0050808 21 0.033
Fly
single organism cell adhesion GO:0098602 29 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
Human Zebrafish Fly
cellular macromolecule metabolic process GO:0044260 391 0.033
Human Zebrafish Mouse Worm Fly
cellular response to decreased oxygen levels GO:0036294 1 0.033
regulation of nucleic acid templated transcription GO:1903506 213 0.032
regulation of molecular function GO:0065009 70 0.032
negative regulation of developmental process GO:0051093 65 0.032
positive regulation of cell activation GO:0050867 1 0.032
positive regulation of cytokine production GO:0001819 2 0.032
regulation of oocyte development GO:0060281 3 0.032
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.032
cellular carbohydrate metabolic process GO:0044262 4 0.032
Human Fly
cellular response to biotic stimulus GO:0071216 3 0.031
myotube cell development GO:0014904 35 0.031
germ cell development GO:0007281 22 0.031
determination of dorsal ventral asymmetry GO:0048262 34 0.031
regulation of protein localization to nucleus GO:1900180 2 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
neural tube formation GO:0001841 16 0.030
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.030
negative regulation of smoothened signaling pathway GO:0045879 6 0.030
carboxylic acid metabolic process GO:0019752 22 0.029
regulation of translational initiation GO:0006446 1 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
anatomical structure arrangement GO:0048532 2 0.029
regulation of nervous system development GO:0051960 90 0.029
Zebrafish
hemopoiesis GO:0030097 183 0.029
proteolysis GO:0006508 38 0.029
regulation of cell proliferation GO:0042127 37 0.028
specification of axis polarity GO:0065001 4 0.028
negative regulation of cell fate specification GO:0009996 11 0.028
angiogenesis GO:0001525 158 0.028
centrosome cycle GO:0007098 1 0.028
cell adhesion GO:0007155 40 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
muscle cell differentiation GO:0042692 139 0.028
regulation of gene expression GO:0010468 265 0.028
muscle organ development GO:0007517 101 0.028
single organism reproductive process GO:0044702 40 0.028
Fly
maintenance of location GO:0051235 4 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.027
development of primary female sexual characteristics GO:0046545 4 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
melanin metabolic process GO:0006582 2 0.027
negative regulation of chemotaxis GO:0050922 4 0.027
pronephros development GO:0048793 69 0.027
negative regulation of cellular biosynthetic process GO:0031327 55 0.027
establishment of localization GO:0051234 244 0.026
Fly
centrosome duplication GO:0051298 1 0.026
regulation of phosphate metabolic process GO:0019220 43 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
negative regulation of reproductive process GO:2000242 3 0.026
rhombomere development GO:0021546 19 0.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
apoptotic process involved in development GO:1902742 2 0.026
cellular response to starvation GO:0009267 1 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
regulation of protein phosphorylation GO:0001932 18 0.025
smoothened signaling pathway GO:0007224 30 0.025
Fly
positive regulation of secretion by cell GO:1903532 1 0.025
germ line stem cell maintenance GO:0030718 2 0.025
positive regulation of developmental process GO:0051094 50 0.025
negative regulation of translational initiation GO:0045947 1 0.025
mesodermal cell differentiation GO:0048333 21 0.025
regulation of cell cell adhesion GO:0022407 13 0.025
regulation of neuron projection regeneration GO:0070570 7 0.025
positive regulation of multi organism process GO:0043902 3 0.024
negative regulation of cellular component organization GO:0051129 16 0.024
regulation of blood vessel size GO:0050880 2 0.024
negative regulation of embryonic development GO:0045992 11 0.024
nucleic acid metabolic process GO:0090304 244 0.024
non canonical wnt signaling pathway GO:0035567 13 0.024
regulation of gastrulation GO:0010470 24 0.024
eye development GO:0001654 277 0.024
regulation of cellular protein metabolic process GO:0032268 52 0.024
cellular response to organic substance GO:0071310 105 0.024
Zebrafish
striated muscle tissue development GO:0014706 110 0.024
cellular response to nutrient levels GO:0031669 2 0.024
regulation of cardiac muscle tissue development GO:0055024 1 0.023
pancreas development GO:0031016 84 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
neural plate regionalization GO:0060897 10 0.023
positive regulation of catabolic process GO:0009896 4 0.023
adult behavior GO:0030534 2 0.023
positive regulation of jnk cascade GO:0046330 3 0.023
cell recognition GO:0008037 19 0.023
anterior posterior axis specification GO:0009948 20 0.023
neuroblast proliferation GO:0007405 2 0.023
organic acid metabolic process GO:0006082 31 0.023
Human Zebrafish Mouse Worm Fly
spinal cord anterior posterior patterning GO:0021512 1 0.023
regulation of hormone secretion GO:0046883 2 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
Zebrafish
determination of left right asymmetry in nervous system GO:0035545 4 0.023
ear morphogenesis GO:0042471 64 0.023
cell morphogenesis involved in differentiation GO:0000904 195 0.022
Zebrafish Mouse Fly
positive regulation of molecular function GO:0044093 33 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
germ line stem cell division GO:0042078 1 0.022
paraxial mesoderm morphogenesis GO:0048340 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
positive regulation of transport GO:0051050 2 0.022
positive regulation of immune effector process GO:0002699 3 0.022
protein stabilization GO:0050821 2 0.021
positive regulation of cell cycle GO:0045787 3 0.021
positive regulation of cell communication GO:0010647 56 0.021
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.021
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
regulation of developmental growth GO:0048638 38 0.021
Zebrafish
regulation of glial cell differentiation GO:0045685 4 0.021
striated muscle cell development GO:0055002 108 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
negative regulation of cell differentiation GO:0045596 46 0.021
macromolecule localization GO:0033036 54 0.021
regulation of skeletal muscle tissue development GO:0048641 4 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
aging GO:0007568 2 0.021
autophagy GO:0006914 4 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
regulation of metal ion transport GO:0010959 4 0.020
negative regulation of gastrulation GO:2000542 11 0.020
carbohydrate metabolic process GO:0005975 12 0.020
Human Fly
cellular localization GO:0051641 97 0.020
Fly
developmental cell growth GO:0048588 52 0.020
Zebrafish
regulation of neuronal synaptic plasticity GO:0048168 1 0.020
ear development GO:0043583 127 0.020
gamete generation GO:0007276 33 0.020
Fly
determination of left right asymmetry in diencephalon GO:0035462 4 0.020
organic substance biosynthetic process GO:1901576 289 0.020
Human Zebrafish Mouse Worm Fly
regulation of neurological system process GO:0031644 2 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
protein complex subunit organization GO:0071822 46 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
negative regulation of neuron projection development GO:0010977 9 0.020
oocyte development GO:0048599 14 0.020
nucleocytoplasmic transport GO:0006913 4 0.019
cellular component assembly GO:0022607 170 0.019
determination of dorsal identity GO:0048263 13 0.019
sulfur compound metabolic process GO:0006790 13 0.019
Human Zebrafish Mouse Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.019
Human Zebrafish Mouse Worm Fly
camera type eye morphogenesis GO:0048593 108 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
negative regulation of myeloid cell differentiation GO:0045638 1 0.019
regulation of muscle organ development GO:0048634 9 0.019
macroautophagy GO:0016236 1 0.019
single organismal cell cell adhesion GO:0016337 29 0.019
synaptic transmission GO:0007268 35 0.019
Fly
peripheral nervous system development GO:0007422 55 0.019
dorsal convergence GO:0060030 14 0.019
type b pancreatic cell proliferation GO:0044342 1 0.019
regulation of endothelial cell proliferation GO:0001936 1 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
response to monosaccharide GO:0034284 3 0.019
neurotransmitter transport GO:0006836 2 0.019
actin cytoskeleton organization GO:0030036 63 0.018
amine metabolic process GO:0009308 2 0.018
microtubule organizing center organization GO:0031023 1 0.018
negative regulation of bmp signaling pathway GO:0030514 13 0.018
regulation of collateral sprouting in absence of injury GO:0048696 4 0.018
cognition GO:0050890 1 0.018
response to hypoxia GO:0001666 25 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
peptidyl serine modification GO:0018209 2 0.018
negative regulation of protein transport GO:0051224 3 0.018
positive regulation of secretion GO:0051047 1 0.018
negative regulation of kinase activity GO:0033673 4 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.018
activin receptor signaling pathway GO:0032924 8 0.018
skeletal muscle organ development GO:0060538 78 0.018
somatic stem cell maintenance GO:0035019 1 0.018
multi organism process GO:0051704 134 0.018
Fly
oocyte differentiation GO:0009994 14 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
canonical wnt signaling pathway GO:0060070 48 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
ceramide biosynthetic process GO:0046513 1 0.018
regulation of neuron differentiation GO:0045664 56 0.018
Zebrafish
regulation of smoothened signaling pathway GO:0008589 18 0.018
Fly
nucleic acid templated transcription GO:0097659 181 0.017
response to hexose GO:0009746 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
Human Zebrafish Mouse Worm Fly
collateral sprouting of intact axon in response to injury GO:0048673 2 0.017
rhombomere morphogenesis GO:0021593 17 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
chordate embryonic development GO:0043009 271 0.017
Mouse
response to glucose GO:0009749 3 0.017
secondary metabolic process GO:0019748 3 0.017
regulation of cell projection organization GO:0031344 44 0.017
Zebrafish
apoptotic process GO:0006915 116 0.017
neural plate pattern specification GO:0060896 12 0.017
phagocytosis engulfment GO:0006911 1 0.017
metal ion transport GO:0030001 58 0.017
cell growth GO:0016049 57 0.017
Zebrafish
regulation of cell death GO:0010941 103 0.017
muscle cell development GO:0055001 115 0.016
zymogen activation GO:0031638 3 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
regulation of organ morphogenesis GO:2000027 35 0.016
regionalization GO:0003002 274 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
viral process GO:0016032 1 0.016
skeletal system morphogenesis GO:0048705 102 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of catalytic activity GO:0050790 55 0.016
response to endogenous stimulus GO:0009719 83 0.016
Zebrafish
female gamete generation GO:0007292 14 0.016
regulation of response to nutrient levels GO:0032107 1 0.016
regulation of protein modification process GO:0031399 29 0.016
translational initiation GO:0006413 3 0.016
hormone biosynthetic process GO:0042446 3 0.016
sex determination GO:0007530 1 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
Mouse
cell proliferation GO:0008283 80 0.016
optic placode formation GO:0001743 4 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
central nervous system development GO:0007417 387 0.016
Mouse
actin filament based process GO:0030029 64 0.016
regulation of cell morphogenesis GO:0022604 42 0.016
Zebrafish
negative regulation of mitosis GO:0045839 3 0.016
appendage development GO:0048736 80 0.016
Zebrafish
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
type b pancreatic cell development GO:0003323 4 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
Human Zebrafish Fly
positive regulation of metabolic process GO:0009893 108 0.015
vestibular receptor cell development GO:0060118 3 0.015
otic vesicle morphogenesis GO:0071600 34 0.015
synaptic vesicle localization GO:0097479 1 0.015
Fly
cilium morphogenesis GO:0060271 85 0.015
pigmentation GO:0043473 85 0.015
cellular component biogenesis GO:0044085 178 0.015
nuclear import GO:0051170 3 0.015
positive regulation of cellular protein metabolic process GO:0032270 22 0.015
negative regulation of developmental growth GO:0048640 9 0.015
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
protein import GO:0017038 3 0.015
rhombomere formation GO:0021594 12 0.015
endoderm formation GO:0001706 29 0.015
regulation of response to stress GO:0080134 36 0.015
regulation of bmp signaling pathway GO:0030510 39 0.015
cell proliferation in hindbrain GO:0021534 4 0.015
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.015

ext1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
Human
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.017
Human
disease of cellular proliferation DOID:14566 0 0.017
Human