Danio rerio

0 known processes

eml2

echinoderm microtubule associated protein like 2

(Aliases: wu:fq15f04,zgc:110445,MGC110445)

eml2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.862
cellular nitrogen compound metabolic process GO:0034641 290 0.634
ion transmembrane transport GO:0034220 91 0.514
transmembrane transport GO:0055085 120 0.291
nucleic acid metabolic process GO:0090304 244 0.268
embryonic organ development GO:0048568 381 0.265
oxoacid metabolic process GO:0043436 31 0.242
death GO:0016265 121 0.222
system process GO:0003008 185 0.216
aromatic compound biosynthetic process GO:0019438 217 0.214
central nervous system development GO:0007417 387 0.213
adult behavior GO:0030534 2 0.200
cellular aromatic compound metabolic process GO:0006725 295 0.192
establishment of localization GO:0051234 244 0.192
single organism organelle organization GO:1902589 199 0.190
regulation of ion transmembrane transporter activity GO:0032412 2 0.186
response to stress GO:0006950 263 0.185
regulation of programmed cell death GO:0043067 101 0.185
response to glucose GO:0009749 3 0.183
cellular response to chemical stimulus GO:0070887 157 0.181
transport GO:0006810 220 0.177
cation transmembrane transport GO:0098655 65 0.177
larval development GO:0002164 2 0.159
signal transduction GO:0007165 455 0.154
cell death GO:0008219 121 0.147
protein complex assembly GO:0006461 30 0.146
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.142
neuronal action potential GO:0019228 18 0.141
regulation of nitrogen compound metabolic process GO:0051171 251 0.134
organic cyclic compound metabolic process GO:1901360 301 0.134
response to oxygen containing compound GO:1901700 55 0.131
positive regulation of biological process GO:0048518 253 0.131
nitrogen compound metabolic process GO:0006807 319 0.126
response to carbohydrate GO:0009743 3 0.122
organic acid metabolic process GO:0006082 31 0.120
single organism localization GO:1902578 225 0.118
inorganic cation transmembrane transport GO:0098662 50 0.117
response to chemical GO:0042221 320 0.116
regulation of response to stimulus GO:0048583 269 0.116
small molecule metabolic process GO:0044281 77 0.114
regulation of nucleic acid templated transcription GO:1903506 213 0.112
hepaticobiliary system development GO:0061008 98 0.111
carboxylic acid metabolic process GO:0019752 22 0.111
single organism membrane organization GO:0044802 20 0.109
response to external stimulus GO:0009605 264 0.109
heterocycle metabolic process GO:0046483 290 0.102
regulation of cellular biosynthetic process GO:0031326 245 0.100
regulation of macromolecule biosynthetic process GO:0010556 225 0.097
regulation of apoptotic process GO:0042981 98 0.096
organelle localization GO:0051640 49 0.096
regulation of rna metabolic process GO:0051252 224 0.096
endothelial cell migration GO:0043542 19 0.095
multicellular organismal signaling GO:0035637 22 0.094
single organism metabolic process GO:0044710 217 0.093
regulation of transmembrane transporter activity GO:0022898 2 0.092
regulation of multicellular organismal process GO:0051239 277 0.090
protein dephosphorylation GO:0006470 3 0.086
retina morphogenesis in camera type eye GO:0060042 79 0.083
locomotion GO:0040011 313 0.083
regulation of signal transduction GO:0009966 225 0.083
organelle organization GO:0006996 227 0.082
cellular biosynthetic process GO:0044249 286 0.081
cellular amino acid metabolic process GO:0006520 7 0.079
cellular component morphogenesis GO:0032989 336 0.076
gland development GO:0048732 143 0.074
nucleobase containing compound metabolic process GO:0006139 274 0.073
regulation of cellular component organization GO:0051128 86 0.072
nuclear migration GO:0007097 3 0.069
macromolecular complex assembly GO:0065003 35 0.069
meiotic nuclear division GO:0007126 4 0.068
apoptotic process GO:0006915 116 0.068
cellular component assembly GO:0022607 170 0.065
programmed cell death GO:0012501 119 0.064
maintenance of location GO:0051235 4 0.064
cell projection organization GO:0030030 284 0.064
cell proliferation GO:0008283 80 0.064
response to monosaccharide GO:0034284 3 0.063
tube morphogenesis GO:0035239 349 0.060
embryonic heart tube development GO:0035050 133 0.059
enzyme linked receptor protein signaling pathway GO:0007167 106 0.059
negative regulation of biological process GO:0048519 304 0.058
response to abiotic stimulus GO:0009628 122 0.057
Zebrafish
regulation of ion transmembrane transport GO:0034765 18 0.055
microtubule based process GO:0007017 60 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.055
macromolecule biosynthetic process GO:0009059 227 0.054
heterocycle biosynthetic process GO:0018130 215 0.054
embryonic organ morphogenesis GO:0048562 274 0.054
regulation of hormone secretion GO:0046883 2 0.054
regulation of sodium ion transmembrane transporter activity GO:2000649 1 0.053
biosynthetic process GO:0009058 294 0.053
regulation of biological quality GO:0065008 263 0.052
ion transport GO:0006811 114 0.052
cellular response to oxygen containing compound GO:1901701 20 0.050
negative regulation of apoptotic process GO:0043066 55 0.050
transmission of nerve impulse GO:0019226 19 0.049
sensory organ morphogenesis GO:0090596 200 0.049
immune system development GO:0002520 191 0.049
cellular component biogenesis GO:0044085 178 0.049
response to hexose GO:0009746 3 0.048
heart development GO:0007507 313 0.047
response to organic substance GO:0010033 153 0.047
organic substance biosynthetic process GO:1901576 289 0.047
organic cyclic compound biosynthetic process GO:1901362 223 0.047
modification dependent protein catabolic process GO:0019941 3 0.047
regulation of metal ion transport GO:0010959 4 0.047
transcription dna templated GO:0006351 181 0.046
cell morphogenesis GO:0000902 289 0.045
organonitrogen compound metabolic process GO:1901564 74 0.045
brain development GO:0007420 293 0.045
cellular localization GO:0051641 97 0.044
peripheral nervous system neuron differentiation GO:0048934 28 0.044
positive regulation of signal transduction GO:0009967 56 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.043
cellular amide metabolic process GO:0043603 4 0.042
regulation of transporter activity GO:0032409 2 0.042
negative regulation of heart contraction GO:0045822 2 0.041
liver development GO:0001889 96 0.041
lipid digestion GO:0044241 3 0.041
determination of left right symmetry GO:0007368 179 0.041
cell surface receptor signaling pathway GO:0007166 325 0.040
regulation of cellular amine metabolic process GO:0033238 0 0.040
negative regulation of cell death GO:0060548 60 0.040
rna metabolic process GO:0016070 219 0.040
regulation of calcium ion transport GO:0051924 2 0.039
single organism transport GO:0044765 206 0.039
meiotic cell cycle process GO:1903046 3 0.039
regulation of rna biosynthetic process GO:2001141 213 0.039
muscle system process GO:0003012 20 0.038
regulation of signaling GO:0023051 235 0.038
regulation of multicellular organism growth GO:0040014 4 0.037
aging GO:0007568 2 0.037
neuron differentiation GO:0030182 353 0.037
organic hydroxy compound transport GO:0015850 14 0.037
muscle contraction GO:0006936 18 0.037
membrane organization GO:0061024 21 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.036
specification of symmetry GO:0009799 204 0.036
sprouting angiogenesis GO:0002040 53 0.035
regulation of cell communication GO:0010646 232 0.035
cation transport GO:0006812 81 0.035
guanosine containing compound metabolic process GO:1901068 4 0.035
blood vessel morphogenesis GO:0048514 216 0.035
gene expression GO:0010467 252 0.035
cell part morphogenesis GO:0032990 246 0.035
regulation of cell death GO:0010941 103 0.035
smooth muscle contraction GO:0006939 2 0.034
endomembrane system organization GO:0010256 13 0.033
protein stabilization GO:0050821 2 0.033
establishment of localization in cell GO:0051649 77 0.033
inorganic ion transmembrane transport GO:0098660 57 0.033
synaptic vesicle transport GO:0048489 1 0.033
exocytosis GO:0006887 1 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.033
regulation of gene expression GO:0010468 265 0.033
regulation of reproductive process GO:2000241 4 0.032
cellular response to organic substance GO:0071310 105 0.031
inner ear receptor cell development GO:0060119 20 0.031
macromolecule localization GO:0033036 54 0.031
regulation of transmembrane transport GO:0034762 18 0.031
morphogenesis of an epithelium GO:0002009 333 0.030
myeloid cell differentiation GO:0030099 86 0.030
multicellular organism growth GO:0035264 4 0.030
calcium mediated signaling GO:0019722 2 0.030
positive regulation of response to stimulus GO:0048584 80 0.030
endosomal transport GO:0016197 2 0.030
protein localization to plasma membrane GO:0072659 1 0.030
negative regulation of cellular process GO:0048523 283 0.030
positive regulation of transport GO:0051050 2 0.030
proteasomal protein catabolic process GO:0010498 2 0.029
negative regulation of metabolic process GO:0009892 86 0.029
positive regulation of apoptotic signaling pathway GO:2001235 1 0.029
regulation of cell motility GO:2000145 46 0.029
regulation of ion transport GO:0043269 22 0.029
metal ion transport GO:0030001 58 0.029
organelle assembly GO:0070925 110 0.028
single organism membrane fusion GO:0044801 2 0.028
response to radiation GO:0009314 51 0.027
Zebrafish
digestive tract mesoderm development GO:0007502 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
regulation of cellular ph GO:0030641 1 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
positive regulation of metabolic process GO:0009893 108 0.027
amine metabolic process GO:0009308 2 0.027
hemopoiesis GO:0030097 183 0.027
phagocytosis GO:0006909 3 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
neurotransmitter transport GO:0006836 2 0.027
single organism cellular localization GO:1902580 46 0.027
positive regulation of catabolic process GO:0009896 4 0.026
positive regulation of multicellular organismal process GO:0051240 52 0.026
gliogenesis GO:0042063 45 0.026
cellular protein complex assembly GO:0043623 19 0.026
rna biosynthetic process GO:0032774 181 0.026
oligodendrocyte differentiation GO:0048709 23 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
spermatid development GO:0007286 2 0.025
localization of cell GO:0051674 244 0.025
central nervous system neuron differentiation GO:0021953 74 0.025
neurological system process GO:0050877 62 0.025
regulation of cell migration GO:0030334 40 0.025
auditory receptor cell differentiation GO:0042491 15 0.025
mechanoreceptor differentiation GO:0042490 37 0.025
establishment of synaptic vesicle localization GO:0097480 1 0.025
camera type eye development GO:0043010 222 0.025
neuron development GO:0048666 262 0.025
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.025
developmental maturation GO:0021700 34 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
cytoskeleton organization GO:0007010 96 0.024
intracellular signal transduction GO:0035556 85 0.024
hormone transport GO:0009914 2 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
membrane invagination GO:0010324 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
positive regulation of developmental process GO:0051094 50 0.024
membrane lipid metabolic process GO:0006643 10 0.024
ensheathment of neurons GO:0007272 18 0.023
regulation of sodium ion transport GO:0002028 2 0.023
cell cycle g2 m phase transition GO:0044839 4 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
cellular response to dna damage stimulus GO:0006974 24 0.023
regulation of biosynthetic process GO:0009889 250 0.023
macrophage chemotaxis GO:0048246 3 0.022
protein complex biogenesis GO:0070271 30 0.022
purine ribonucleoside biosynthetic process GO:0046129 2 0.022
organic substance transport GO:0071702 58 0.022
determination of bilateral symmetry GO:0009855 204 0.022
positive regulation of cell communication GO:0010647 56 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
regulation of locomotion GO:0040012 55 0.021
lipid catabolic process GO:0016042 4 0.021
cellular response to prostaglandin stimulus GO:0071379 3 0.021
multi organism process GO:0051704 134 0.021
Worm
peptidyl serine phosphorylation GO:0018105 1 0.021
spindle assembly GO:0051225 2 0.021
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.021
regulation of cytokine production GO:0001817 3 0.021
b cell activation GO:0042113 2 0.021
dorsal ventral pattern formation GO:0009953 125 0.021
retina development in camera type eye GO:0060041 146 0.021
response to endogenous stimulus GO:0009719 83 0.020
establishment of organelle localization GO:0051656 45 0.020
organelle fission GO:0048285 23 0.020
regulation of sodium ion transmembrane transport GO:1902305 1 0.020
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.020
homeostatic process GO:0042592 142 0.020
single organism biosynthetic process GO:0044711 71 0.020
establishment of spindle localization GO:0051293 12 0.020
membrane lipid biosynthetic process GO:0046467 2 0.020
convergent extension involved in organogenesis GO:0060029 10 0.020
cellular macromolecular complex assembly GO:0034622 24 0.020
axon development GO:0061564 166 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
regulation of cell shape GO:0008360 1 0.019
hair cell differentiation GO:0035315 32 0.019
nucleus localization GO:0051647 8 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
single organism intracellular transport GO:1902582 25 0.019
leukocyte proliferation GO:0070661 1 0.019
negative regulation of sequestering of calcium ion GO:0051283 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
response to ketone GO:1901654 1 0.019
regulation of molecular function GO:0065009 70 0.018
cellular response to external stimulus GO:0071496 2 0.018
establishment of spindle orientation GO:0051294 10 0.018
peptidyl serine modification GO:0018209 2 0.018
specification of axis polarity GO:0065001 4 0.018
synaptic vesicle localization GO:0097479 1 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
nucleoside triphosphate biosynthetic process GO:0009142 2 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
protein complex subunit organization GO:0071822 46 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
cell projection morphogenesis GO:0048858 244 0.018
tissue migration GO:0090130 37 0.018
regulation of transcription dna templated GO:0006355 213 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of signaling GO:0023056 56 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
developmental growth GO:0048589 166 0.017
female meiotic division GO:0007143 2 0.017
negative regulation of dna metabolic process GO:0051053 4 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
sodium ion transmembrane transport GO:0035725 21 0.017
inner ear receptor cell differentiation GO:0060113 29 0.017
regulation of cell differentiation GO:0045595 142 0.017
chordate embryonic development GO:0043009 271 0.017
response to oxidative stress GO:0006979 11 0.017
embryonic hemopoiesis GO:0035162 53 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
calcium ion transmembrane transport GO:0070588 13 0.017
autophagy GO:0006914 4 0.017
nuclear division GO:0000280 23 0.017
regulation of primary metabolic process GO:0080090 311 0.017
regulation of blood pressure GO:0008217 1 0.017
cellular response to nutrient levels GO:0031669 2 0.016
response to nitrogen compound GO:1901698 19 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
glial cell differentiation GO:0010001 42 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
regulation of developmental process GO:0050793 247 0.016
axon ensheathment in central nervous system GO:0032291 2 0.016
sensory perception of mechanical stimulus GO:0050954 16 0.016
stem cell proliferation GO:0072089 4 0.016
action potential GO:0001508 19 0.016
response to drug GO:0042493 3 0.016
cellular catabolic process GO:0044248 27 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
negative chemotaxis GO:0050919 1 0.016
regulation of binding GO:0051098 3 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
regulation of membrane potential GO:0042391 23 0.015
immunoglobulin mediated immune response GO:0016064 3 0.015
growth GO:0040007 174 0.015
meiotic chromosome segregation GO:0045132 3 0.015
embryonic skeletal joint morphogenesis GO:0060272 3 0.015
lipid metabolic process GO:0006629 52 0.015
regulation of gtpase activity GO:0043087 2 0.015
cell cycle process GO:0022402 53 0.015
blood circulation GO:0008015 87 0.015
cytokinesis GO:0000910 3 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
hatching GO:0035188 4 0.015
angiogenesis GO:0001525 158 0.014
regulation of glial cell differentiation GO:0045685 4 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
cytoskeleton dependent intracellular transport GO:0030705 10 0.014
cellular component movement GO:0006928 335 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
cellular response to retinoic acid GO:0071300 1 0.014
inner ear development GO:0048839 126 0.014
regulation of ph GO:0006885 3 0.014
lipid storage GO:0019915 1 0.014
regulation of cell development GO:0060284 100 0.014
myeloid leukocyte mediated immunity GO:0002444 1 0.014
intracellular transport GO:0046907 32 0.013
vasculature development GO:0001944 278 0.013
regulation of cellular component movement GO:0051270 55 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
detection of external stimulus GO:0009581 24 0.013
regulation of blood vessel endothelial cell migration GO:0043535 5 0.013
erythrocyte homeostasis GO:0034101 55 0.013
leukocyte activation GO:0045321 12 0.013
cell cycle arrest GO:0007050 1 0.013
striated muscle cell proliferation GO:0014855 7 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
regulation of metabolic process GO:0019222 359 0.013
lymphocyte proliferation GO:0046651 1 0.013
digestive tract morphogenesis GO:0048546 231 0.013
mononuclear cell proliferation GO:0032943 1 0.013
pyruvate metabolic process GO:0006090 1 0.013
adherens junction maintenance GO:0034334 2 0.013
sphingolipid metabolic process GO:0006665 9 0.013
regulation of cytokine mediated signaling pathway GO:0001959 3 0.013
cellular component maintenance GO:0043954 3 0.012
urogenital system development GO:0001655 97 0.012
actin cytoskeleton organization GO:0030036 63 0.012
positive regulation of cellular process GO:0048522 201 0.012
cortical granule exocytosis GO:0060471 1 0.012
ectodermal placode development GO:0071696 37 0.012
organism emergence from protective structure GO:0071684 4 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
response to hydrogen peroxide GO:0042542 3 0.012
ribonucleotide metabolic process GO:0009259 27 0.012
neuron projection development GO:0031175 180 0.012
ribonucleoside biosynthetic process GO:0042455 2 0.012
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
axon cargo transport GO:0008088 2 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
osteoclast development GO:0036035 1 0.012
pigmentation GO:0043473 85 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of cell activation GO:0050865 1 0.012
meiotic spindle organization GO:0000212 1 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
neurotransmitter secretion GO:0007269 2 0.012
epithelial cell differentiation GO:0030855 116 0.011
positive regulation of cell differentiation GO:0045597 30 0.011
astrocyte differentiation GO:0048708 1 0.011
glial cell development GO:0021782 20 0.011
regulation of catalytic activity GO:0050790 55 0.011
lymphocyte activation GO:0046649 10 0.011
apoptotic signaling pathway GO:0097190 23 0.011
heart contraction GO:0060047 71 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
axonogenesis GO:0007409 152 0.011
nucleic acid templated transcription GO:0097659 181 0.011
protein targeting to membrane GO:0006612 1 0.011
very long chain fatty acid metabolic process GO:0000038 4 0.011
cell cell signaling GO:0007267 52 0.011
b cell mediated immunity GO:0019724 3 0.011
phagosome maturation GO:0090382 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
membrane fusion GO:0061025 2 0.011
cellular response to lipid GO:0071396 39 0.011
circulatory system process GO:0003013 87 0.011
regulation of alcohol biosynthetic process GO:1902930 1 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
microglia differentiation GO:0014004 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
medulla oblongata development GO:0021550 4 0.010
regulation of protein transport GO:0051223 3 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
microtubule cytoskeleton organization GO:0000226 33 0.010
positive regulation of neural retina development GO:0061075 1 0.010
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.010
sensory perception GO:0007600 39 0.010
myeloid cell homeostasis GO:0002262 56 0.010
organophosphate metabolic process GO:0019637 37 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
negative regulation of phosphate metabolic process GO:0045936 13 0.010
epithelial cell migration GO:0010631 25 0.010

eml2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.171
disease of anatomical entity DOID:7 0 0.171
hematopoietic system disease DOID:74 0 0.171