Danio rerio

41 known processes

obscnl

obscurin like

obscnl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of synapse organization GO:0050807 3 0.102
sensory organ development GO:0007423 393 0.096
cell surface receptor signaling pathway GO:0007166 325 0.052
regulation of neural precursor cell proliferation GO:2000177 3 0.046
nuclear transport GO:0051169 4 0.044
larval development GO:0002164 2 0.044
cell matrix adhesion GO:0007160 4 0.044
transmission of nerve impulse GO:0019226 19 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.041
regulation of dendrite development GO:0050773 3 0.040
mitochondrion organization GO:0007005 4 0.040
mechanosensory behavior GO:0007638 2 0.038
regulation of protein transport GO:0051223 3 0.037
development of primary female sexual characteristics GO:0046545 4 0.037
protein heterooligomerization GO:0051291 1 0.036
cellular component morphogenesis GO:0032989 336 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
rna localization GO:0006403 4 0.033
circadian sleep wake cycle sleep GO:0050802 1 0.033
female gonad development GO:0008585 4 0.033
positive regulation of transport GO:0051050 2 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
muscle tissue development GO:0060537 110 0.032
single organism transport GO:0044765 206 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.032
regulation of stem cell proliferation GO:0072091 2 0.032
sleep GO:0030431 1 0.031
protein localization to nucleus GO:0034504 3 0.030
central nervous system development GO:0007417 387 0.030
neuromuscular synaptic transmission GO:0007274 2 0.029
nuclear import GO:0051170 3 0.029
aging GO:0007568 2 0.028
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
protein import GO:0017038 3 0.027
regulation of biosynthetic process GO:0009889 250 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
heterocycle metabolic process GO:0046483 290 0.026
neuronal action potential GO:0019228 18 0.026
regulation of multicellular organismal development GO:2000026 223 0.025
regulation of cytokine production GO:0001817 3 0.025
regulation of neurogenesis GO:0050767 87 0.025
regulation of cell development GO:0060284 100 0.025
phagocytosis GO:0006909 3 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
regulation of synapse assembly GO:0051963 3 0.024
cell part morphogenesis GO:0032990 246 0.024
single organism organelle organization GO:1902589 199 0.024
digestive tract development GO:0048565 265 0.024
adult behavior GO:0030534 2 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
regulation of protein targeting GO:1903533 2 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.023
female sex differentiation GO:0046660 4 0.023
convergent extension GO:0060026 118 0.023
locomotion GO:0040011 313 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
single organism nuclear import GO:1902593 3 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
generation of neurons GO:0048699 385 0.023
cell migration GO:0016477 237 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
intracellular mrna localization GO:0008298 1 0.022
protein import into nucleus GO:0006606 3 0.022
digestive tract morphogenesis GO:0048546 231 0.022
erythrocyte differentiation GO:0030218 54 0.022
meiotic nuclear division GO:0007126 4 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
single organism localization GO:1902578 225 0.021
erythrocyte homeostasis GO:0034101 55 0.021
cellular respiration GO:0045333 3 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
eye development GO:0001654 277 0.020
regulation of binding GO:0051098 3 0.020
tube morphogenesis GO:0035239 349 0.020
cellular amine metabolic process GO:0044106 2 0.020
multicellular organismal signaling GO:0035637 22 0.019
cell projection organization GO:0030030 284 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
cytoplasm organization GO:0007028 4 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
synaptic transmission cholinergic GO:0007271 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
negative regulation of protein kinase activity GO:0006469 4 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
locomotor rhythm GO:0045475 3 0.018
determination of bilateral symmetry GO:0009855 204 0.018
neurological system process GO:0050877 62 0.018
single organism metabolic process GO:0044710 217 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
regulation of cell projection assembly GO:0060491 4 0.018
protein targeting to nucleus GO:0044744 3 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
response to chemical GO:0042221 320 0.018
positive regulation of myeloid cell differentiation GO:0045639 2 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
peptidyl serine modification GO:0018209 2 0.017
heart morphogenesis GO:0003007 156 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of nervous system development GO:0051960 90 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
camera type eye morphogenesis GO:0048593 108 0.017
negative regulation of defense response GO:0031348 2 0.017
response to amino acid GO:0043200 2 0.016
camera type eye development GO:0043010 222 0.016
swimming behavior GO:0036269 8 0.016
signal transduction GO:0007165 455 0.016
circadian sleep wake cycle GO:0042745 2 0.016
neuron differentiation GO:0030182 353 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
ovulation cycle process GO:0022602 2 0.016
cell projection morphogenesis GO:0048858 244 0.015
regulation of transporter activity GO:0032409 2 0.015
embryonic organ development GO:0048568 381 0.015
stem cell proliferation GO:0072089 4 0.015
regulation of localization GO:0032879 104 0.015
regulation of receptor activity GO:0010469 2 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of protein complex assembly GO:0043254 3 0.015
nucleic acid metabolic process GO:0090304 244 0.015
organelle organization GO:0006996 227 0.015
regulation of developmental process GO:0050793 247 0.015
erythrocyte development GO:0048821 24 0.015
regulation of circadian rhythm GO:0042752 4 0.015
nuclear export GO:0051168 1 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
macromolecule modification GO:0043412 111 0.015
cell aging GO:0007569 2 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
astrocyte differentiation GO:0048708 1 0.015
regulation of cell projection organization GO:0031344 44 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
energy reserve metabolic process GO:0006112 2 0.014
vacuolar transport GO:0007034 2 0.014
specification of symmetry GO:0009799 204 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
regulation of postsynaptic membrane potential GO:0060078 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
cellular aldehyde metabolic process GO:0006081 4 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
cellular component assembly GO:0022607 170 0.014
meiotic cell cycle process GO:1903046 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
skeletal muscle organ development GO:0060538 78 0.014
response to light stimulus GO:0009416 46 0.014
regulation of cell differentiation GO:0045595 142 0.014
gene expression GO:0010467 252 0.014
regulation of transmembrane transport GO:0034762 18 0.014
heart development GO:0007507 313 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.013
cellular macromolecule metabolic process GO:0044260 391 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
response to stress GO:0006950 263 0.013
cellular component movement GO:0006928 335 0.013
myeloid cell homeostasis GO:0002262 56 0.013
lamellipodium organization GO:0097581 1 0.013
stem cell differentiation GO:0048863 117 0.013
amine metabolic process GO:0009308 2 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
larval behavior GO:0030537 5 0.013
cellular response to external stimulus GO:0071496 2 0.013
positive regulation of cytokine production GO:0001819 2 0.013
regulation of biological quality GO:0065008 263 0.013
cilium assembly GO:0042384 58 0.013
action potential GO:0001508 19 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
organic substance biosynthetic process GO:1901576 289 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
angiogenesis GO:0001525 158 0.013
organic acid metabolic process GO:0006082 31 0.013
skeletal muscle fiber development GO:0048741 35 0.013
cell projection assembly GO:0030031 64 0.013
sarcomerogenesis GO:0048769 4 0.013
cellular component disassembly GO:0022411 1 0.012
ion transmembrane transport GO:0034220 91 0.012
regulation of protein catabolic process GO:0042176 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
transport GO:0006810 220 0.012
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.012
lipid homeostasis GO:0055088 3 0.012
response to drug GO:0042493 3 0.012
small molecule metabolic process GO:0044281 77 0.012
stem cell maintenance GO:0019827 4 0.012
spermatid development GO:0007286 2 0.012
positive regulation of cell cycle GO:0045787 3 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of signaling GO:0023051 235 0.012
cellular protein catabolic process GO:0044257 4 0.012
response to external biotic stimulus GO:0043207 97 0.012
axonogenesis GO:0007409 152 0.012
mitochondrial transport GO:0006839 2 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
oxoacid metabolic process GO:0043436 31 0.012
biosynthetic process GO:0009058 294 0.011
negative regulation of protein transport GO:0051224 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cellular ketone metabolic process GO:0042180 11 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
centrosome organization GO:0051297 1 0.011
regulation of neuron migration GO:2001222 2 0.011
membrane invagination GO:0010324 1 0.011
peptidyl lysine methylation GO:0018022 3 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
protein localization to plasma membrane GO:0072659 1 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
regulation of neuron projection development GO:0010975 40 0.011
cell substrate junction assembly GO:0007044 2 0.011
histone h3 k4 methylation GO:0051568 2 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
endosomal transport GO:0016197 2 0.011
anterior posterior pattern specification GO:0009952 152 0.011
smooth muscle contraction GO:0006939 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.010
lipid catabolic process GO:0016042 4 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
rna metabolic process GO:0016070 219 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
regulation of inflammatory response GO:0050727 2 0.010
regulation of response to stimulus GO:0048583 269 0.010
negative regulation of catabolic process GO:0009895 3 0.010
protein dephosphorylation GO:0006470 3 0.010
regeneration GO:0031099 91 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
regulation of membrane potential GO:0042391 23 0.010
hydrogen peroxide metabolic process GO:0042743 2 0.010
glial cell proliferation GO:0014009 4 0.010
homeostasis of number of cells GO:0048872 62 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
muscle structure development GO:0061061 196 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
regulation of signal transduction GO:0009966 225 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of organelle assembly GO:1902115 4 0.010

obscnl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
nervous system disease DOID:863 0 0.039
musculoskeletal system disease DOID:17 0 0.022
cardiovascular system disease DOID:1287 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
immune system disease DOID:2914 0 0.011