Danio rerio

0 known processes

nlgn4b

neuroligin 4b

(Aliases: nlgn4a)

nlgn4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron neuron synaptic transmission GO:0007270 1 0.927
adult behavior GO:0030534 2 0.874
regulation of postsynaptic membrane potential GO:0060078 1 0.853
monoamine transport GO:0015844 1 0.772
membrane hyperpolarization GO:0060081 1 0.685
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.671
cellular component maintenance GO:0043954 3 0.621
regulation of synapse organization GO:0050807 3 0.515
glutamate receptor signaling pathway GO:0007215 1 0.505
regulation of glutamate receptor signaling pathway GO:1900449 1 0.503
ion transmembrane transport GO:0034220 91 0.494
regulation of dendrite development GO:0050773 3 0.418
regulation of transmembrane transporter activity GO:0022898 2 0.398
regulation of synaptic plasticity GO:0048167 1 0.390
regulation of inhibitory postsynaptic membrane potential GO:0060080 1 0.305
neuromuscular synaptic transmission GO:0007274 2 0.265
regulation of cell projection organization GO:0031344 44 0.235
postsynaptic membrane organization GO:0001941 3 0.227
regulation of transmembrane transport GO:0034762 18 0.213
regulation of receptor activity GO:0010469 2 0.176
regulation of synapse structure and activity GO:0050803 5 0.169
regulation of neurogenesis GO:0050767 87 0.164
synaptic transmission GO:0007268 35 0.160
cell projection organization GO:0030030 284 0.143
cell part morphogenesis GO:0032990 246 0.138
regulation of transporter activity GO:0032409 2 0.130
positive regulation of transport GO:0051050 2 0.127
visual behavior GO:0007632 10 0.125
locomotory behavior GO:0007626 34 0.118
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.114
embryonic limb morphogenesis GO:0030326 2 0.110
transmembrane transport GO:0055085 120 0.104
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.096
neuron projection development GO:0031175 180 0.094
hydrogen peroxide metabolic process GO:0042743 2 0.094
single organism localization GO:1902578 225 0.090
cellular macromolecule metabolic process GO:0044260 391 0.085
synaptic growth at neuromuscular junction GO:0051124 2 0.081
cell surface receptor signaling pathway GO:0007166 325 0.076
synaptic transmission glycinergic GO:0060012 1 0.074
regulation of metal ion transport GO:0010959 4 0.073
synapse assembly GO:0007416 9 0.070
eye development GO:0001654 277 0.070
pigment granule localization GO:0051875 25 0.069
neuron projection morphogenesis GO:0048812 161 0.067
glial cell differentiation GO:0010001 42 0.066
cell morphogenesis GO:0000902 289 0.065
regulation of ion transmembrane transporter activity GO:0032412 2 0.065
heterocycle metabolic process GO:0046483 290 0.063
cell cell signaling GO:0007267 52 0.061
regulation of ion transmembrane transport GO:0034765 18 0.053
cellular respiration GO:0045333 3 0.053
forebrain cell migration GO:0021885 1 0.052
nucleobase containing compound metabolic process GO:0006139 274 0.050
behavior GO:0007610 74 0.046
response to chemical GO:0042221 320 0.045
positive regulation of signaling GO:0023056 56 0.045
alternative mrna splicing via spliceosome GO:0000380 1 0.044
negative regulation of secretion by cell GO:1903531 2 0.043
nucleic acid metabolic process GO:0090304 244 0.042
synapse organization GO:0050808 21 0.042
stem cell fate commitment GO:0048865 1 0.042
regulation of mrna processing GO:0050684 3 0.041
purine ribonucleoside biosynthetic process GO:0046129 2 0.041
regulation of system process GO:0044057 40 0.040
gene expression GO:0010467 252 0.040
phagocytosis GO:0006909 3 0.039
nitrogen compound metabolic process GO:0006807 319 0.038
central nervous system neuron axonogenesis GO:0021955 18 0.038
modification dependent macromolecule catabolic process GO:0043632 3 0.038
cellular component assembly GO:0022607 170 0.038
regulation of multicellular organismal development GO:2000026 223 0.038
ubiquitin dependent protein catabolic process GO:0006511 3 0.037
neurological system process GO:0050877 62 0.037
regulation of cellular amine metabolic process GO:0033238 0 0.037
neuron differentiation GO:0030182 353 0.037
response to amine GO:0014075 1 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.036
regulation of mrna splicing via spliceosome GO:0048024 3 0.036
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.035
regeneration GO:0031099 91 0.035
negative chemotaxis GO:0050919 1 0.034
regulation of developmental process GO:0050793 247 0.033
regulation of cell differentiation GO:0045595 142 0.032
signal transduction GO:0007165 455 0.032
gliogenesis GO:0042063 45 0.032
regulation of tube size GO:0035150 2 0.032
regulation of nervous system development GO:0051960 90 0.032
generation of neurons GO:0048699 385 0.031
regulation of cell morphogenesis GO:0022604 42 0.031
developmental maturation GO:0021700 34 0.031
response to amino acid GO:0043200 2 0.030
camera type eye development GO:0043010 222 0.030
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.030
modification dependent protein catabolic process GO:0019941 3 0.030
regulation of blood pressure GO:0008217 1 0.030
tube morphogenesis GO:0035239 349 0.030
cell projection morphogenesis GO:0048858 244 0.030
regulation of response to stimulus GO:0048583 269 0.030
cell migration GO:0016477 237 0.029
sensory organ development GO:0007423 393 0.029
transport GO:0006810 220 0.029
dendrite development GO:0016358 9 0.028
nucleotide metabolic process GO:0009117 28 0.028
negative regulation of neuron projection development GO:0010977 9 0.027
renal absorption GO:0070293 1 0.027
regulation of membrane potential GO:0042391 23 0.026
regulation of anatomical structure morphogenesis GO:0022603 130 0.026
dendrite guidance GO:0070983 0 0.026
regulation of biological quality GO:0065008 263 0.026
locomotion GO:0040011 313 0.025
response to radiation GO:0009314 51 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
organic acid catabolic process GO:0016054 3 0.025
response to light stimulus GO:0009416 46 0.025
regulation of inflammatory response GO:0050727 2 0.024
central nervous system neuron development GO:0021954 29 0.024
response to external stimulus GO:0009605 264 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.024
axonogenesis GO:0007409 152 0.023
developmental cell growth GO:0048588 52 0.023
response to food GO:0032094 1 0.023
response to abiotic stimulus GO:0009628 122 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
larval development GO:0002164 2 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
respiratory electron transport chain GO:0022904 2 0.022
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.022
brain development GO:0007420 293 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
dopamine metabolic process GO:0042417 2 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.021
oxidation reduction process GO:0055114 41 0.021
primitive erythrocyte differentiation GO:0060319 5 0.021
digestive system development GO:0055123 289 0.020
retinal ganglion cell axon guidance GO:0031290 35 0.020
negative regulation of hormone secretion GO:0046888 2 0.019
serotonin transport GO:0006837 1 0.019
regulation of neuron projection development GO:0010975 40 0.019
regulation of synaptic transmission GO:0050804 4 0.019
dendrite morphogenesis GO:0048813 5 0.019
response to amphetamine GO:0001975 1 0.019
taxis GO:0042330 109 0.019
positive regulation of signal transduction GO:0009967 56 0.019
multicellular organism growth GO:0035264 4 0.018
negative regulation of cellular process GO:0048523 283 0.018
cellular response to oxygen levels GO:0071453 1 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
meiotic nuclear division GO:0007126 4 0.017
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.017
regulation of signaling GO:0023051 235 0.017
amine metabolic process GO:0009308 2 0.017
regulation of calcium ion transport GO:0051924 2 0.017
neurotransmitter secretion GO:0007269 2 0.017
endocrine process GO:0050886 2 0.017
embryonic skeletal joint development GO:0072498 3 0.017
endocrine hormone secretion GO:0060986 2 0.017
protein homooligomerization GO:0051260 3 0.017
cellular amine metabolic process GO:0044106 2 0.016
small molecule catabolic process GO:0044282 3 0.016
positive regulation of cellular protein metabolic process GO:0032270 22 0.016
oxoacid metabolic process GO:0043436 31 0.016
organic acid metabolic process GO:0006082 31 0.016
neuron development GO:0048666 262 0.016
axon guidance GO:0007411 86 0.016
regulation of neuron differentiation GO:0045664 56 0.016
regulation of molecular function GO:0065009 70 0.016
regulation of cellular component organization GO:0051128 86 0.016
mitotic cell cycle embryonic GO:0045448 2 0.016
outflow tract morphogenesis GO:0003151 1 0.016
negative regulation of oxidative stress induced cell death GO:1903202 2 0.016
response to glucose GO:0009749 3 0.016
single organism membrane organization GO:0044802 20 0.016
cellular amino acid biosynthetic process GO:0008652 2 0.016
cell death in response to oxidative stress GO:0036473 2 0.016
regulation of cellular response to oxidative stress GO:1900407 2 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.015
cation transmembrane transport GO:0098655 65 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
cellular protein catabolic process GO:0044257 4 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of protein complex assembly GO:0043254 3 0.015
erythrocyte differentiation GO:0030218 54 0.015
oocyte maturation GO:0001556 4 0.014
growth GO:0040007 174 0.014
sleep GO:0030431 1 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
regulation of circadian rhythm GO:0042752 4 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
positive regulation of synapse assembly GO:0051965 1 0.014
catecholamine metabolic process GO:0006584 2 0.014
cell motility GO:0048870 244 0.014
positive regulation of biological process GO:0048518 253 0.014
establishment of localization GO:0051234 244 0.014
axon midline choice point recognition GO:0016199 4 0.014
electron transport chain GO:0022900 2 0.014
proteasomal protein catabolic process GO:0010498 2 0.013
negative regulation of cellular component movement GO:0051271 18 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of transport GO:0051049 45 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
regulation of localization GO:0032879 104 0.013
regulation of hormone secretion GO:0046883 2 0.013
mechanosensory behavior GO:0007638 2 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
biosynthetic process GO:0009058 294 0.013
response to hexose GO:0009746 3 0.013
startle response GO:0001964 4 0.013
hormone transport GO:0009914 2 0.013
regulation of locomotion GO:0040012 55 0.013
regulation of protein catabolic process GO:0042176 1 0.012
ion transport GO:0006811 114 0.012
regulation of endocrine process GO:0044060 2 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
negative regulation of protein kinase b signaling GO:0051898 2 0.012
regulation of oxidative stress induced cell death GO:1903201 2 0.012
posterior lateral line system development GO:0048915 46 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
spliceosomal complex assembly GO:0000245 1 0.012
positive regulation of cell communication GO:0010647 56 0.012
response to vitamin b3 GO:0033552 2 0.012
gonadotropin secretion GO:0032274 1 0.012
organic hydroxy compound transport GO:0015850 14 0.012
response to unfolded protein GO:0006986 2 0.012
regulation of neurological system process GO:0031644 2 0.012
purine ribonucleotide metabolic process GO:0009150 27 0.012
protein secretion GO:0009306 1 0.012
negative regulation of protein transport GO:0051224 3 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
glucocorticoid metabolic process GO:0008211 2 0.012
regulation of cytokine production GO:0001817 3 0.012
female gonad development GO:0008585 4 0.011
protein sumoylation GO:0016925 2 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
regulation of rna metabolic process GO:0051252 224 0.011
lipid catabolic process GO:0016042 4 0.011
regulation of blood vessel size GO:0050880 2 0.011
erythrocyte homeostasis GO:0034101 55 0.011
axon development GO:0061564 166 0.011
regulation of cell communication GO:0010646 232 0.011
embryonic organ development GO:0048568 381 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
aging GO:0007568 2 0.011
positive regulation of camp biosynthetic process GO:0030819 2 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.011
regulation of gonadotropin secretion GO:0032276 1 0.011
rrna catabolic process GO:0016075 1 0.011
multi organism process GO:0051704 134 0.010
single organism behavior GO:0044708 24 0.010
neuroblast differentiation GO:0014016 1 0.010
axon choice point recognition GO:0016198 5 0.010
phosphorylation GO:0016310 69 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
cognition GO:0050890 1 0.010
organ regeneration GO:0031100 1 0.010
negative regulation of gliogenesis GO:0014014 1 0.010

nlgn4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
autistic disorder DOID:12849 0 0.878
pervasive developmental disorder DOID:0060040 0 0.878
autism spectrum disorder DOID:0060041 0 0.878
disease of mental health DOID:150 0 0.878
developmental disorder of mental health DOID:0060037 0 0.878
disease of anatomical entity DOID:7 0 0.021
synucleinopathy DOID:0050890 0 0.016
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
nervous system disease DOID:863 0 0.016
parkinson s disease DOID:14330 0 0.012