Danio rerio

0 known processes

guf1

GUF1 GTPase homolog (S. cerevisiae)

(Aliases: im:6906935,wu:fc88c11)

guf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.077
aging GO:0007568 2 0.055
maintenance of location GO:0051235 4 0.041
regulation of multicellular organism growth GO:0040014 4 0.038
multicellular organism growth GO:0035264 4 0.037
lipid storage GO:0019915 1 0.037
meiotic nuclear division GO:0007126 4 0.036
regulation of mrna processing GO:0050684 3 0.036
positive regulation of transport GO:0051050 2 0.035
phagocytosis GO:0006909 3 0.033
nuclear transport GO:0051169 4 0.032
nucleocytoplasmic transport GO:0006913 4 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
nitrogen compound metabolic process GO:0006807 319 0.029
regulation of mrna splicing via spliceosome GO:0048024 3 0.029
regulation of cytokine production GO:0001817 3 0.029
regulation of protein transport GO:0051223 3 0.029
amine metabolic process GO:0009308 2 0.028
stem cell maintenance GO:0019827 4 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
endosomal transport GO:0016197 2 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
cellular amine metabolic process GO:0044106 2 0.027
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.027
meiotic cell cycle process GO:1903046 3 0.025
cellular protein catabolic process GO:0044257 4 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
proteasomal protein catabolic process GO:0010498 2 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
autophagy GO:0006914 4 0.024
protein import GO:0017038 3 0.024
positive regulation of catabolic process GO:0009896 4 0.024
protein acetylation GO:0006473 2 0.024
regulation of protein catabolic process GO:0042176 1 0.024
rna localization GO:0006403 4 0.024
mitochondrion organization GO:0007005 4 0.024
regulation of meiotic cell cycle GO:0051445 1 0.023
heterocycle metabolic process GO:0046483 290 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
response to drug GO:0042493 3 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
cellular ketone metabolic process GO:0042180 11 0.022
single organism nuclear import GO:1902593 3 0.022
peptidyl lysine acetylation GO:0018394 2 0.022
signal transduction GO:0007165 455 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
regulation of cell activation GO:0050865 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
internal protein amino acid acetylation GO:0006475 2 0.021
regulation of gene expression GO:0010468 265 0.021
gtp metabolic process GO:0046039 4 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
protein localization to nucleus GO:0034504 3 0.021
regulation of protein complex assembly GO:0043254 3 0.021
nuclear import GO:0051170 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
single organism membrane fusion GO:0044801 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
cellular component disassembly GO:0022411 1 0.021
gene expression GO:0010467 252 0.021
positive regulation of cell cycle GO:0045787 3 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
protein import into nucleus GO:0006606 3 0.020
microtubule organizing center organization GO:0031023 1 0.020
membrane fusion GO:0061025 2 0.020
gtp catabolic process GO:0006184 2 0.020
stem cell proliferation GO:0072089 4 0.020
cytokinesis GO:0000910 3 0.020
protein acylation GO:0043543 3 0.020
atp catabolic process GO:0006200 4 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
rna metabolic process GO:0016070 219 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of cell shape GO:0008360 1 0.019
response to uv GO:0009411 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
spermatid development GO:0007286 2 0.019
regulation of metabolic process GO:0019222 359 0.019
positive regulation of secretion GO:0051047 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
response to stress GO:0006950 263 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
response to chemical GO:0042221 320 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
cellular response to nutrient levels GO:0031669 2 0.018
leukocyte proliferation GO:0070661 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
nucleic acid metabolic process GO:0090304 244 0.018
cellular response to starvation GO:0009267 1 0.018
female sex differentiation GO:0046660 4 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cellular biosynthetic process GO:0044249 286 0.018
positive regulation of translation GO:0045727 1 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
transport GO:0006810 220 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of binding GO:0051098 3 0.018
organelle fusion GO:0048284 3 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
nuclear export GO:0051168 1 0.018
positive regulation of cytokine production GO:0001819 2 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
double strand break repair GO:0006302 3 0.018
protein polymerization GO:0051258 4 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
tissue remodeling GO:0048771 4 0.018
regulation of protein targeting GO:1903533 2 0.018
protein localization to plasma membrane GO:0072659 1 0.018
protein secretion GO:0009306 1 0.017
single organism metabolic process GO:0044710 217 0.017
cellular response to radiation GO:0071478 4 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
locomotor rhythm GO:0045475 3 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
positive regulation of cell activation GO:0050867 1 0.017
organelle organization GO:0006996 227 0.017
stem cell division GO:0017145 1 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
b cell activation GO:0042113 2 0.017
central nervous system development GO:0007417 387 0.017
regulation of rna metabolic process GO:0051252 224 0.017
protein dephosphorylation GO:0006470 3 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
small molecule metabolic process GO:0044281 77 0.016
regulation of organelle assembly GO:1902115 4 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
phagocytosis engulfment GO:0006911 1 0.016
cellular component movement GO:0006928 335 0.016
establishment of localization GO:0051234 244 0.016
spermatid differentiation GO:0048515 2 0.016
regulation of biological quality GO:0065008 263 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
biosynthetic process GO:0009058 294 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
regulation of cell communication GO:0010646 232 0.016
response to external stimulus GO:0009605 264 0.016
organic substance biosynthetic process GO:1901576 289 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
centrosome organization GO:0051297 1 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
female gonad development GO:0008585 4 0.015
regulation of biosynthetic process GO:0009889 250 0.015
golgi vesicle transport GO:0048193 3 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
transcription dna templated GO:0006351 181 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
response to carbohydrate GO:0009743 3 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
response to topologically incorrect protein GO:0035966 2 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
negative regulation of biological process GO:0048519 304 0.015
negative regulation of cytokine production GO:0001818 1 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
regulation of primary metabolic process GO:0080090 311 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
mononuclear cell proliferation GO:0032943 1 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
protein complex disassembly GO:0043241 1 0.015
neuron differentiation GO:0030182 353 0.015
positive regulation of immune effector process GO:0002699 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
membrane invagination GO:0010324 1 0.015
cognition GO:0050890 1 0.015
regulation of autophagy GO:0010506 3 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
peptidyl serine modification GO:0018209 2 0.014
protein metabolic process GO:0019538 183 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of response to stimulus GO:0048583 269 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
generation of neurons GO:0048699 385 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
cell migration GO:0016477 237 0.014
macromolecular complex disassembly GO:0032984 1 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
single organism organelle organization GO:1902589 199 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
secondary metabolic process GO:0019748 3 0.014
single fertilization GO:0007338 3 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
lymphocyte proliferation GO:0046651 1 0.014
cellular respiration GO:0045333 3 0.014
carbohydrate homeostasis GO:0033500 1 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of jun kinase activity GO:0043506 3 0.014
regulation of reproductive process GO:2000241 4 0.014
regulation of gtpase activity GO:0043087 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
adult behavior GO:0030534 2 0.014
meiotic chromosome segregation GO:0045132 3 0.013
single organism transport GO:0044765 206 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
locomotion GO:0040011 313 0.013
actin filament polymerization GO:0030041 2 0.013
negative regulation of kinase activity GO:0033673 4 0.013
response to hexose GO:0009746 3 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
cellular component morphogenesis GO:0032989 336 0.013
protein polyubiquitination GO:0000209 4 0.013
immune system process GO:0002376 241 0.013
nucleic acid templated transcription GO:0097659 181 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
cellular component biogenesis GO:0044085 178 0.013
regulation of blood pressure GO:0008217 1 0.013
interspecies interaction between organisms GO:0044419 4 0.013
sensory organ development GO:0007423 393 0.013
nucleobase containing compound transport GO:0015931 2 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of circadian rhythm GO:0042752 4 0.013
cellular response to light stimulus GO:0071482 4 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
rna transport GO:0050658 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
peptide transport GO:0015833 1 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
localization of cell GO:0051674 244 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
regulation of muscle contraction GO:0006937 3 0.013
cellular amide metabolic process GO:0043603 4 0.013
cellular protein metabolic process GO:0044267 129 0.013
compound eye development GO:0048749 2 0.013
brain development GO:0007420 293 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
antimicrobial humoral response GO:0019730 2 0.013
exocytosis GO:0006887 1 0.013
negative regulation of nuclear division GO:0051784 3 0.013
establishment of rna localization GO:0051236 3 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of protein polymerization GO:0032271 2 0.013
regulation of metal ion transport GO:0010959 4 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
regulation of signaling GO:0023051 235 0.012
regulation of developmental process GO:0050793 247 0.012
eye development GO:0001654 277 0.012
meiosis i GO:0007127 1 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
system process GO:0003008 185 0.012
glucose homeostasis GO:0042593 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
rna export from nucleus GO:0006405 1 0.012
cell projection morphogenesis GO:0048858 244 0.012
cell projection organization GO:0030030 284 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of signal transduction GO:0009966 225 0.012
response to glucose GO:0009749 3 0.012
lamellipodium assembly GO:0030032 1 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
vasculature development GO:0001944 278 0.012
macroautophagy GO:0016236 1 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
cell part morphogenesis GO:0032990 246 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
protein heterooligomerization GO:0051291 1 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
chemosensory behavior GO:0007635 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
head development GO:0060322 303 0.012
negative regulation of catabolic process GO:0009895 3 0.012
growth GO:0040007 174 0.012
response to nutrient GO:0007584 3 0.012
nucleic acid transport GO:0050657 2 0.012
single organism localization GO:1902578 225 0.012
endosome organization GO:0007032 2 0.012
viral process GO:0016032 1 0.012
immune system development GO:0002520 191 0.012
mitotic cytokinesis GO:0000281 3 0.012
vacuolar transport GO:0007034 2 0.012
cell substrate adhesion GO:0031589 4 0.011
negative regulation of secretion GO:0051048 2 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of jak stat cascade GO:0046425 3 0.011
negative regulation of defense response GO:0031348 2 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
cell motility GO:0048870 244 0.011
neuron development GO:0048666 262 0.011
somatic stem cell maintenance GO:0035019 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
cell substrate junction assembly GO:0007044 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
negative regulation of cellular process GO:0048523 283 0.011
multi organism cellular process GO:0044764 2 0.011
activation of mapk activity GO:0000187 3 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
cellular component assembly GO:0022607 170 0.011
lipid homeostasis GO:0055088 3 0.011
primary neural tube formation GO:0014020 1 0.011
cellular protein modification process GO:0006464 100 0.011
digestive system development GO:0055123 289 0.011
translational initiation GO:0006413 3 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
blood vessel development GO:0001568 246 0.011
protein stabilization GO:0050821 2 0.011
lamellipodium organization GO:0097581 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
cell death GO:0008219 121 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
macromolecule modification GO:0043412 111 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
dna templated transcription elongation GO:0006354 3 0.011
negative regulation of protein transport GO:0051224 3 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
mrna transport GO:0051028 2 0.011
cell matrix adhesion GO:0007160 4 0.011
tube morphogenesis GO:0035239 349 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
tube closure GO:0060606 1 0.011
hemopoiesis GO:0030097 183 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
spindle assembly GO:0051225 2 0.011
post embryonic organ development GO:0048569 4 0.011
developmental programmed cell death GO:0010623 4 0.011
embryonic organ development GO:0048568 381 0.011
developmental growth GO:0048589 166 0.011
protein modification process GO:0036211 100 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
positive regulation of multi organism process GO:0043902 3 0.010
protein homooligomerization GO:0051260 3 0.010
apoptotic process GO:0006915 116 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
cell aging GO:0007569 2 0.010
fertilization GO:0009566 3 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
regulation of cell projection assembly GO:0060491 4 0.010
camera type eye development GO:0043010 222 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
germ line stem cell maintenance GO:0030718 2 0.010
mitochondrial transport GO:0006839 2 0.010
response to organic substance GO:0010033 153 0.010
regulation of transporter activity GO:0032409 2 0.010
regulation of organ growth GO:0046620 3 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
death GO:0016265 121 0.010
positive regulation of cellular process GO:0048522 201 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
cilium movement GO:0003341 26 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010

guf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012
cardiovascular system disease DOID:1287 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
myopathy DOID:423 0 0.011