Danio rerio

2 known processes

ugt1ab

UDP glucuronosyltransferase 1 family a, b

(Aliases: zgc:123097,zgc:66393,Ugt1a3)

ugt1ab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.077
aging GO:0007568 2 0.072
single organism metabolic process GO:0044710 217 0.066
organic cyclic compound metabolic process GO:1901360 301 0.062
positive regulation of transport GO:0051050 2 0.061
response to chemical GO:0042221 320 0.060
small molecule metabolic process GO:0044281 77 0.052
multicellular organism growth GO:0035264 4 0.050
maintenance of location GO:0051235 4 0.050
nitrogen compound metabolic process GO:0006807 319 0.048
regulation of biological quality GO:0065008 263 0.047
regulation of cellular metabolic process GO:0031323 320 0.046
signal transduction GO:0007165 455 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.044
response to stress GO:0006950 263 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.042
response to external stimulus GO:0009605 264 0.041
carboxylic acid catabolic process GO:0046395 3 0.041
positive regulation of biological process GO:0048518 253 0.040
response to drug GO:0042493 3 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.040
organic substance biosynthetic process GO:1901576 289 0.040
regulation of metabolic process GO:0019222 359 0.039
response to nutrient GO:0007584 3 0.038
single organism localization GO:1902578 225 0.038
biosynthetic process GO:0009058 294 0.038
heterocycle metabolic process GO:0046483 290 0.037
lipid storage GO:0019915 1 0.037
transport GO:0006810 220 0.036
cellular macromolecule metabolic process GO:0044260 391 0.036
guanosine containing compound catabolic process GO:1901069 2 0.035
lipid homeostasis GO:0055088 3 0.035
response to external biotic stimulus GO:0043207 97 0.033
gtp metabolic process GO:0046039 4 0.033
lipid catabolic process GO:0016042 4 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.032
lipid oxidation GO:0034440 1 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
cellular response to external stimulus GO:0071496 2 0.031
oxoacid metabolic process GO:0043436 31 0.031
stem cell proliferation GO:0072089 4 0.030
regulation of developmental process GO:0050793 247 0.029
nuclear transport GO:0051169 4 0.029
response to organic substance GO:0010033 153 0.029
generation of neurons GO:0048699 385 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
protein import into nucleus GO:0006606 3 0.029
fatty acid oxidation GO:0019395 1 0.029
regulation of cytoplasmic transport GO:1903649 4 0.028
negative regulation of biological process GO:0048519 304 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
negative regulation of cellular process GO:0048523 283 0.028
response to biotic stimulus GO:0009607 97 0.028
nucleic acid metabolic process GO:0090304 244 0.028
single organism transport GO:0044765 206 0.028
regulation of biosynthetic process GO:0009889 250 0.028
organic acid metabolic process GO:0006082 31 0.027
regulation of tube size GO:0035150 2 0.027
positive regulation of catabolic process GO:0009896 4 0.027
gtp catabolic process GO:0006184 2 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
phagocytosis GO:0006909 3 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
locomotion GO:0040011 313 0.027
response to carbohydrate GO:0009743 3 0.027
cellular ketone metabolic process GO:0042180 11 0.027
regulation of cytokine production GO:0001817 3 0.026
gene expression GO:0010467 252 0.026
rna metabolic process GO:0016070 219 0.026
regulation of epithelial cell proliferation GO:0050678 3 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
protein import GO:0017038 3 0.026
cell substrate adhesion GO:0031589 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
regulation of primary metabolic process GO:0080090 311 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
positive regulation of secretion GO:0051047 1 0.025
system process GO:0003008 185 0.025
cellular component movement GO:0006928 335 0.025
regulation of inflammatory response GO:0050727 2 0.025
regulation of blood vessel size GO:0050880 2 0.025
response to monosaccharide GO:0034284 3 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
immune system process GO:0002376 241 0.024
establishment of localization GO:0051234 244 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
protein localization to nucleus GO:0034504 3 0.024
regulation of gene expression GO:0010468 265 0.024
regulation of establishment of protein localization GO:0070201 4 0.023
homeostatic process GO:0042592 142 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
neuroblast proliferation GO:0007405 2 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
ion transport GO:0006811 114 0.023
hormone transport GO:0009914 2 0.023
regulation of hormone secretion GO:0046883 2 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
rna biosynthetic process GO:0032774 181 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
protein targeting to nucleus GO:0044744 3 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
multi organism process GO:0051704 134 0.022
small molecule catabolic process GO:0044282 3 0.022
nuclear import GO:0051170 3 0.022
response to other organism GO:0051707 97 0.022
regulation of metal ion transport GO:0010959 4 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
stem cell maintenance GO:0019827 4 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
transmembrane transport GO:0055085 120 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
positive regulation of cell cycle GO:0045787 3 0.022
transcription dna templated GO:0006351 181 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cellular biosynthetic process GO:0044249 286 0.021
amine metabolic process GO:0009308 2 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
single organism nuclear import GO:1902593 3 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
regulation of protein complex assembly GO:0043254 3 0.020
mitochondrion organization GO:0007005 4 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
heart development GO:0007507 313 0.020
adult behavior GO:0030534 2 0.020
regulation of cell differentiation GO:0045595 142 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
response to hexose GO:0009746 3 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of response to stimulus GO:0048583 269 0.020
vasculature development GO:0001944 278 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
organelle organization GO:0006996 227 0.020
positive regulation of immune effector process GO:0002699 3 0.020
cellular lipid catabolic process GO:0044242 3 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of cell activation GO:0050865 1 0.020
positive regulation of cellular process GO:0048522 201 0.020
positive regulation of cell activation GO:0050867 1 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
peptide transport GO:0015833 1 0.020
phosphatidylinositol mediated signaling GO:0048015 2 0.019
regulation of binding GO:0051098 3 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of blood pressure GO:0008217 1 0.019
response to bacterium GO:0009617 58 0.019
determination of bilateral symmetry GO:0009855 204 0.019
cell migration GO:0016477 237 0.019
regulation of signal transduction GO:0009966 225 0.018
regulation of protein transport GO:0051223 3 0.018
monocarboxylic acid catabolic process GO:0072329 3 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.018
nucleic acid templated transcription GO:0097659 181 0.018
programmed cell death GO:0012501 119 0.018
growth GO:0040007 174 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
specification of symmetry GO:0009799 204 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
central nervous system development GO:0007417 387 0.018
intracellular signal transduction GO:0035556 85 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
inositol lipid mediated signaling GO:0048017 2 0.018
hormone secretion GO:0046879 2 0.017
regulation of transcription dna templated GO:0006355 213 0.017
neuron differentiation GO:0030182 353 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
negative regulation of catabolic process GO:0009895 3 0.017
localization of cell GO:0051674 244 0.017
regulation of synapse organization GO:0050807 3 0.017
autophagy GO:0006914 4 0.017
regulation of protein catabolic process GO:0042176 1 0.017
alcohol biosynthetic process GO:0046165 2 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
head development GO:0060322 303 0.017
regulation of gtpase activity GO:0043087 2 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
regulation of cell communication GO:0010646 232 0.016
apoptotic process GO:0006915 116 0.016
meiotic cell cycle process GO:1903046 3 0.016
secondary metabolic process GO:0019748 3 0.016
protein metabolic process GO:0019538 183 0.016
cytokinesis GO:0000910 3 0.016
cellular protein catabolic process GO:0044257 4 0.016
glucose homeostasis GO:0042593 1 0.016
brain development GO:0007420 293 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
cellular response to organic substance GO:0071310 105 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
hepaticobiliary system development GO:0061008 98 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
blood vessel development GO:0001568 246 0.016
regulation of reproductive process GO:2000241 4 0.016
response to vitamin GO:0033273 3 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
membrane fusion GO:0061025 2 0.016
acylglycerol homeostasis GO:0055090 2 0.016
response to corticosteroid GO:0031960 1 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
positive regulation of cytokine production GO:0001819 2 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of protein targeting GO:1903533 2 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
oxidation reduction process GO:0055114 41 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
embryonic organ development GO:0048568 381 0.015
phosphorus metabolic process GO:0006793 109 0.015
digestive system development GO:0055123 289 0.015
eye development GO:0001654 277 0.015
neuron development GO:0048666 262 0.015
protein localization to plasma membrane GO:0072659 1 0.015
cellular component morphogenesis GO:0032989 336 0.015
cellular protein metabolic process GO:0044267 129 0.015
blood circulation GO:0008015 87 0.015
cellular response to starvation GO:0009267 1 0.015
response to abiotic stimulus GO:0009628 122 0.015
response to wounding GO:0009611 116 0.015
tube morphogenesis GO:0035239 349 0.015
triglyceride homeostasis GO:0070328 2 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
interspecies interaction between organisms GO:0044419 4 0.015
cognition GO:0050890 1 0.015
fatty acid catabolic process GO:0009062 1 0.015
meiotic nuclear division GO:0007126 4 0.015
single organism organelle organization GO:1902589 199 0.015
regulation of cell shape GO:0008360 1 0.014
developmental growth GO:0048589 166 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
immune system development GO:0002520 191 0.014
protein acetylation GO:0006473 2 0.014
response to endogenous stimulus GO:0009719 83 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of signaling GO:0023051 235 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
multicellular organismal metabolic process GO:0044236 2 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
gland development GO:0048732 143 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
liver development GO:0001889 96 0.014
single organism biosynthetic process GO:0044711 71 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
exocytosis GO:0006887 1 0.014
hemopoiesis GO:0030097 183 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
camera type eye development GO:0043010 222 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
cellular component assembly GO:0022607 170 0.014
cell projection morphogenesis GO:0048858 244 0.014
response to hormone GO:0009725 48 0.014
carbohydrate homeostasis GO:0033500 1 0.014
digestive tract morphogenesis GO:0048546 231 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
positive regulation of blood circulation GO:1903524 2 0.013
sensory organ development GO:0007423 393 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
neurotransmitter transport GO:0006836 2 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
death GO:0016265 121 0.013
determination of left right symmetry GO:0007368 179 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
response to alkaloid GO:0043279 2 0.013
cellular component disassembly GO:0022411 1 0.013
adherens junction organization GO:0034332 4 0.013
lipid metabolic process GO:0006629 52 0.013
cellular component biogenesis GO:0044085 178 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of rna metabolic process GO:0051252 224 0.013
protein polymerization GO:0051258 4 0.013
regulation of cell development GO:0060284 100 0.013
cell motility GO:0048870 244 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
defense response GO:0006952 47 0.013
positive regulation of metabolic process GO:0009893 108 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
membrane invagination GO:0010324 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
macromolecule modification GO:0043412 111 0.013
protein complex disassembly GO:0043241 1 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
cation transport GO:0006812 81 0.012
protein acylation GO:0043543 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
response to glucose GO:0009749 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
mononuclear cell proliferation GO:0032943 1 0.012
b cell activation GO:0042113 2 0.012
cellular response to oxygen levels GO:0071453 1 0.012
circulatory system process GO:0003013 87 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
cell death GO:0008219 121 0.012
fat soluble vitamin metabolic process GO:0006775 4 0.012
defense response to other organism GO:0098542 33 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
single organism membrane fusion GO:0044801 2 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
cellular response to steroid hormone stimulus GO:0071383 31 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
response to lipid GO:0033993 60 0.012
regulation of cell projection assembly GO:0060491 4 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
organic acid catabolic process GO:0016054 3 0.012
rna localization GO:0006403 4 0.012
spermatid differentiation GO:0048515 2 0.012
regulation of programmed cell death GO:0043067 101 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
negative regulation of metabolic process GO:0009892 86 0.011
tissue remodeling GO:0048771 4 0.011
regulation of apoptotic process GO:0042981 98 0.011
wound healing GO:0042060 90 0.011
response to steroid hormone GO:0048545 35 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
antimicrobial humoral response GO:0019730 2 0.011
response to organic cyclic compound GO:0014070 51 0.011
multicellular organismal response to stress GO:0033555 2 0.011
gastrulation GO:0007369 208 0.011
chemical homeostasis GO:0048878 49 0.011
negative regulation of defense response GO:0031348 2 0.011
actin filament based movement GO:0030048 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
cell part morphogenesis GO:0032990 246 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
angiogenesis GO:0001525 158 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
blood vessel morphogenesis GO:0048514 216 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
fertilization GO:0009566 3 0.011
germ line stem cell maintenance GO:0030718 2 0.011
cellular response to stress GO:0033554 62 0.011
negative regulation of kinase activity GO:0033673 4 0.011
cell projection organization GO:0030030 284 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
fatty acid transport GO:0015908 1 0.011
negative regulation of cytokine production GO:0001818 1 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
post embryonic organ development GO:0048569 4 0.011
cellular response to hypoxia GO:0071456 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
spermatid development GO:0007286 2 0.011
anion transport GO:0006820 38 0.011
endocrine process GO:0050886 2 0.011
phagocytosis engulfment GO:0006911 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
multicellular organismal macromolecule metabolic process GO:0044259 2 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
heart process GO:0003015 71 0.010
cellular response to lipid GO:0071396 39 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
stem cell division GO:0017145 1 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
hormone biosynthetic process GO:0042446 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
smooth muscle contraction GO:0006939 2 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
cellular lipid metabolic process GO:0044255 36 0.010
epithelial tube morphogenesis GO:0060562 148 0.010

ugt1ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
disease of metabolism DOID:0014667 0 0.019
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
inherited metabolic disorder DOID:655 0 0.013