Danio rerio

0 known processes

wdhd1

WD repeat and HMG-box DNA binding protein 1

(Aliases: AND-1,wu:fa11f10,wu:fb77d12,zgc:92585)

wdhd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
recombinational repair GO:0000725 1 0.707
double strand break repair via homologous recombination GO:0000724 1 0.581
double strand break repair GO:0006302 3 0.555
cellular macromolecule metabolic process GO:0044260 391 0.471
centrosome cycle GO:0007098 1 0.399
dna biosynthetic process GO:0071897 3 0.388
response to stress GO:0006950 263 0.360
mitotic recombination GO:0006312 2 0.351
cellular macromolecule biosynthetic process GO:0034645 224 0.346
embryo development ending in birth or egg hatching GO:0009792 271 0.325
cellular nitrogen compound metabolic process GO:0034641 290 0.285
negative regulation of nuclear division GO:0051784 3 0.270
meiotic chromosome segregation GO:0045132 3 0.256
dna repair GO:0006281 6 0.248
meiotic cell cycle process GO:1903046 3 0.211
cellular aromatic compound metabolic process GO:0006725 295 0.210
regulation of meiotic cell cycle GO:0051445 1 0.208
modification dependent protein catabolic process GO:0019941 3 0.195
heterocycle metabolic process GO:0046483 290 0.191
organic cyclic compound metabolic process GO:1901360 301 0.181
negative regulation of cell cycle process GO:0010948 9 0.180
nucleobase containing compound metabolic process GO:0006139 274 0.180
immune system process GO:0002376 241 0.178
meiosis i GO:0007127 1 0.177
mitotic cell cycle process GO:1903047 48 0.173
regulation of chromosome segregation GO:0051983 1 0.169
cellular biosynthetic process GO:0044249 286 0.162
spindle assembly GO:0051225 2 0.161
regulation of dna recombination GO:0000018 2 0.160
nitrogen compound metabolic process GO:0006807 319 0.159
organic substance biosynthetic process GO:1901576 289 0.158
centrosome organization GO:0051297 1 0.157
single organism organelle organization GO:1902589 199 0.150
response to external stimulus GO:0009605 264 0.147
biosynthetic process GO:0009058 294 0.144
meiotic nuclear division GO:0007126 4 0.141
mitotic nuclear division GO:0007067 18 0.134
centrosome duplication GO:0051298 1 0.134
aging GO:0007568 2 0.129
mitotic dna integrity checkpoint GO:0044774 4 0.123
regulation of dna replication GO:0006275 3 0.109
larval development GO:0002164 2 0.108
rna metabolic process GO:0016070 219 0.107
organelle organization GO:0006996 227 0.107
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.104
deoxyribonucleotide metabolic process GO:0009262 1 0.103
organic cyclic compound biosynthetic process GO:1901362 223 0.101
locomotion GO:0040011 313 0.101
microtubule based process GO:0007017 60 0.096
dna metabolic process GO:0006259 27 0.096
double strand break repair via nonhomologous end joining GO:0006303 1 0.090
regulation of protein catabolic process GO:0042176 1 0.090
histone phosphorylation GO:0016572 2 0.089
regulation of cellular biosynthetic process GO:0031326 245 0.089
macromolecule biosynthetic process GO:0009059 227 0.087
non recombinational repair GO:0000726 2 0.086
regulation of mitotic cell cycle GO:0007346 25 0.085
nucleic acid metabolic process GO:0090304 244 0.083
transport GO:0006810 220 0.083
protein metabolic process GO:0019538 183 0.082
cellular component assembly GO:0022607 170 0.080
synapsis GO:0007129 1 0.080
establishment of localization GO:0051234 244 0.080
regulation of primary metabolic process GO:0080090 311 0.079
organelle fission GO:0048285 23 0.077
mitotic cell cycle GO:0000278 64 0.076
cellular component movement GO:0006928 335 0.075
mitotic g2 m transition checkpoint GO:0044818 3 0.072
multicellular organism growth GO:0035264 4 0.071
cellular response to stress GO:0033554 62 0.066
positive regulation of cell cycle GO:0045787 3 0.066
phosphorus metabolic process GO:0006793 109 0.065
g2 m transition of mitotic cell cycle GO:0000086 4 0.065
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.064
positive regulation of rna biosynthetic process GO:1902680 57 0.062
cellular macromolecule catabolic process GO:0044265 12 0.060
response to drug GO:0042493 3 0.059
dna catabolic process GO:0006308 1 0.058
positive regulation of catabolic process GO:0009896 4 0.057
maintenance of location GO:0051235 4 0.057
cellular response to dna damage stimulus GO:0006974 24 0.056
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
cellular response to external stimulus GO:0071496 2 0.054
negative regulation of mitosis GO:0045839 3 0.054
regulation of cellular amine metabolic process GO:0033238 0 0.053
regulation of multicellular organism growth GO:0040014 4 0.052
cell cycle GO:0007049 93 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.051
negative regulation of cell division GO:0051782 4 0.051
g1 s transition of mitotic cell cycle GO:0000082 1 0.050
nucleobase containing compound biosynthetic process GO:0034654 205 0.050
cellular protein catabolic process GO:0044257 4 0.048
apoptotic process GO:0006915 116 0.048
negative regulation of mitotic cell cycle GO:0045930 11 0.048
immune system development GO:0002520 191 0.047
cell migration GO:0016477 237 0.046
reciprocal dna recombination GO:0035825 1 0.045
amine metabolic process GO:0009308 2 0.045
cell proliferation GO:0008283 80 0.045
dna recombination GO:0006310 5 0.045
microtubule cytoskeleton organization GO:0000226 33 0.045
sensory organ development GO:0007423 393 0.044
reciprocal meiotic recombination GO:0007131 1 0.044
mitotic dna damage checkpoint GO:0044773 4 0.043
single organism biosynthetic process GO:0044711 71 0.043
regulation of gene silencing GO:0060968 1 0.043
response to abiotic stimulus GO:0009628 122 0.043
regulation of cell cycle GO:0051726 52 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.041
regulation of transcription dna templated GO:0006355 213 0.041
gene expression GO:0010467 252 0.040
cellular amine metabolic process GO:0044106 2 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
cell cycle g1 s phase transition GO:0044843 1 0.038
lipid catabolic process GO:0016042 4 0.038
cell cycle g2 m phase transition GO:0044839 4 0.037
regulation of gene expression GO:0010468 265 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.036
cell cycle process GO:0022402 53 0.036
reproduction GO:0000003 40 0.036
chromosome organization GO:0051276 31 0.035
deoxyribonucleotide biosynthetic process GO:0009263 1 0.035
cytoskeleton organization GO:0007010 96 0.035
peptidyl threonine phosphorylation GO:0018107 1 0.035
negative regulation of cellular process GO:0048523 283 0.035
localization of cell GO:0051674 244 0.034
sex determination GO:0007530 1 0.034
aromatic compound biosynthetic process GO:0019438 217 0.033
regulation of protein ubiquitination GO:0031396 3 0.033
pronuclear migration GO:0035046 1 0.033
regulation of protein import into nucleus GO:0042306 2 0.033
regulation of metabolic process GO:0019222 359 0.033
programmed cell death GO:0012501 119 0.033
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.033
response to light stimulus GO:0009416 46 0.033
dna templated transcription elongation GO:0006354 3 0.033
negative regulation of biosynthetic process GO:0009890 55 0.032
protein modification process GO:0036211 100 0.032
phosphorylation GO:0016310 69 0.032
regulation of mitotic cell cycle phase transition GO:1901990 8 0.032
regulation of cellular metabolic process GO:0031323 320 0.031
response to alkaloid GO:0043279 2 0.031
cell death GO:0008219 121 0.031
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.031
negative regulation of dna metabolic process GO:0051053 4 0.031
single organism metabolic process GO:0044710 217 0.030
mononuclear cell proliferation GO:0032943 1 0.030
vasculature development GO:0001944 278 0.030
negative regulation of biological process GO:0048519 304 0.029
positive regulation of dna metabolic process GO:0051054 1 0.029
single organism reproductive process GO:0044702 40 0.029
protein acetylation GO:0006473 2 0.029
phosphate containing compound metabolic process GO:0006796 108 0.028
mitotic metaphase plate congression GO:0007080 1 0.028
mitotic cell cycle phase transition GO:0044772 9 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
heterocycle biosynthetic process GO:0018130 215 0.027
regulation of rna metabolic process GO:0051252 224 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
negative regulation of catabolic process GO:0009895 3 0.027
male meiosis GO:0007140 2 0.027
cellular protein modification process GO:0006464 100 0.027
nuclear division GO:0000280 23 0.026
cellular lipid catabolic process GO:0044242 3 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
lymphocyte proliferation GO:0046651 1 0.026
positive regulation of histone modification GO:0031058 1 0.026
hatching GO:0035188 4 0.026
cellular component biogenesis GO:0044085 178 0.026
chromosome organization involved in meiosis GO:0070192 1 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
cytokinesis GO:0000910 3 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.025
maintenance of dna repeat elements GO:0043570 2 0.025
oocyte maturation GO:0001556 4 0.025
establishment of protein localization to organelle GO:0072594 4 0.024
regulation of biosynthetic process GO:0009889 250 0.024
cell motility GO:0048870 244 0.024
leukocyte proliferation GO:0070661 1 0.024
regulation of cell cycle phase transition GO:1901987 8 0.023
macromolecule modification GO:0043412 111 0.023
negative regulation of cell cycle GO:0045786 14 0.023
intra s dna damage checkpoint GO:0031573 1 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
response to yeast GO:0001878 23 0.023
regulation of proteolysis GO:0030162 24 0.023
lens development in camera type eye GO:0002088 22 0.023
heart development GO:0007507 313 0.023
oxoacid metabolic process GO:0043436 31 0.023
protein polyubiquitination GO:0000209 4 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
death GO:0016265 121 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
signal transduction GO:0007165 455 0.022
carboxylic acid metabolic process GO:0019752 22 0.021
negative regulation of gene expression GO:0010629 65 0.021
regulation of dna templated transcription in response to stress GO:0043620 0 0.021
negative regulation of rna metabolic process GO:0051253 48 0.021
transcription dna templated GO:0006351 181 0.021
mitotic sister chromatid segregation GO:0000070 6 0.021
hepatocyte differentiation GO:0070365 1 0.021
blood vessel development GO:0001568 246 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
proteolysis GO:0006508 38 0.020
reproductive process GO:0022414 40 0.020
multi organism process GO:0051704 134 0.020
macromolecule catabolic process GO:0009057 15 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
negative regulation of metabolic process GO:0009892 86 0.019
immunoglobulin mediated immune response GO:0016064 3 0.019
negative regulation of histone methylation GO:0031061 1 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
g2 dna damage checkpoint GO:0031572 3 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
protein phosphorylation GO:0006468 47 0.019
b cell activation GO:0042113 2 0.019
single fertilization GO:0007338 3 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
zymogen activation GO:0031638 3 0.018
cellular ketone metabolic process GO:0042180 11 0.018
chromatin organization GO:0006325 22 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
lipid metabolic process GO:0006629 52 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
rna biosynthetic process GO:0032774 181 0.017
response to external biotic stimulus GO:0043207 97 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.017
negative regulation of meiotic cell cycle GO:0051447 1 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.017
nuclear import GO:0051170 3 0.016
regulation of lipid catabolic process GO:0050994 2 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
positive regulation of chromatin modification GO:1903310 1 0.016
immunoglobulin production GO:0002377 1 0.016
intrinsic apoptotic signaling pathway GO:0097193 20 0.016
cell cycle phase transition GO:0044770 9 0.016
phagocytosis GO:0006909 3 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
signal transduction by p53 class mediator GO:0072331 13 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
collateral sprouting in absence of injury GO:0048669 4 0.015
negative regulation of cell cycle phase transition GO:1901988 5 0.015
developmental process involved in reproduction GO:0003006 27 0.015
vesicle mediated transport GO:0016192 22 0.015
apoptotic signaling pathway GO:0097190 23 0.015
regulation of protein targeting GO:1903533 2 0.015
dna replication GO:0006260 6 0.015
response to chemical GO:0042221 320 0.015
antimicrobial humoral response GO:0019730 2 0.015
regulation of cell cycle process GO:0010564 20 0.014
nucleic acid templated transcription GO:0097659 181 0.014
response to biotic stimulus GO:0009607 97 0.014
rna dependent dna replication GO:0006278 2 0.014
hematopoietic stem cell migration GO:0035701 4 0.014
growth GO:0040007 174 0.014
sister chromatid cohesion GO:0007062 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
b cell mediated immunity GO:0019724 3 0.014
dna alkylation GO:0006305 8 0.014
protein targeting to nucleus GO:0044744 3 0.014
protein import GO:0017038 3 0.014
regulation of programmed cell death GO:0043067 101 0.014
positive regulation of cell division GO:0051781 2 0.014
histone h3 k36 methylation GO:0010452 2 0.013
positive regulation of lipid catabolic process GO:0050996 1 0.013
golgi organization GO:0007030 1 0.013
somatic cell dna recombination GO:0016444 1 0.013
cellular response to radiation GO:0071478 4 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.013
cell division GO:0051301 20 0.013
pyrimidine containing compound metabolic process GO:0072527 3 0.013
microtubule organizing center organization GO:0031023 1 0.013
regulation of protein metabolic process GO:0051246 56 0.013
intracellular signal transduction GO:0035556 85 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
response to amino acid GO:0043200 2 0.013
spindle assembly involved in mitosis GO:0090307 1 0.013
response to fungus GO:0009620 25 0.013
hemopoiesis GO:0030097 183 0.012
eye development GO:0001654 277 0.012
nuclear transport GO:0051169 4 0.012
cellular catabolic process GO:0044248 27 0.012
organic acid metabolic process GO:0006082 31 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
dna integrity checkpoint GO:0031570 6 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
peptidyl serine modification GO:0018209 2 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of cell cycle g2 m phase transition GO:1902749 4 0.012
histone h3 k4 methylation GO:0051568 2 0.012
chromosome segregation GO:0007059 12 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of circadian rhythm GO:0042752 4 0.012
cellular component disassembly GO:0022411 1 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
lateral inhibition GO:0046331 1 0.012
peptidyl threonine modification GO:0018210 1 0.011
fertilization GO:0009566 3 0.011
regulation of mitosis GO:0007088 9 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.011
protein heterooligomerization GO:0051291 1 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.011
cell aging GO:0007569 2 0.011
developmental growth GO:0048589 166 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
positive regulation of biological process GO:0048518 253 0.011
small molecule metabolic process GO:0044281 77 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
angiogenesis GO:0001525 158 0.011
stem cell maintenance GO:0019827 4 0.011
positive regulation of chromosome segregation GO:0051984 1 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
protein import into nucleus GO:0006606 3 0.011
regulation of apoptotic process GO:0042981 98 0.011
gene silencing GO:0016458 4 0.011
mitotic g2 dna damage checkpoint GO:0007095 3 0.010
mitotic cell cycle checkpoint GO:0007093 5 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
muscle cell development GO:0055001 115 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
cellular response to organic substance GO:0071310 105 0.010
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 1 0.010
cellular response to light stimulus GO:0071482 4 0.010
dna replication checkpoint GO:0000076 1 0.010
organism emergence from protective structure GO:0071684 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010

wdhd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.053
disease of cellular proliferation DOID:14566 0 0.053
disease of anatomical entity DOID:7 0 0.052
organ system cancer DOID:0050686 0 0.034
large intestine cancer DOID:5672 0 0.019
gastrointestinal system cancer DOID:3119 0 0.019
intestinal cancer DOID:10155 0 0.019
colorectal cancer DOID:9256 0 0.014
thoracic cancer DOID:5093 0 0.014
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.010