Danio rerio

0 known processes

prkar1aa

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a

(Aliases: im:7047729,prkar1a,zgc:92515)

prkar1aa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.408
heterocycle biosynthetic process GO:0018130 215 0.369
regulation of macromolecule biosynthetic process GO:0010556 225 0.296
gene expression GO:0010467 252 0.281
autophagy GO:0006914 4 0.273
larval development GO:0002164 2 0.241
heterocycle metabolic process GO:0046483 290 0.223
aromatic compound biosynthetic process GO:0019438 217 0.222
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.208
cellular biosynthetic process GO:0044249 286 0.205
defense response to other organism GO:0098542 33 0.203
regulation of gene expression GO:0010468 265 0.190
regulation of biosynthetic process GO:0009889 250 0.186
cell surface receptor signaling pathway GO:0007166 325 0.171
nitrogen compound metabolic process GO:0006807 319 0.170
negative regulation of biological process GO:0048519 304 0.166
cellular macromolecule biosynthetic process GO:0034645 224 0.159
transcription dna templated GO:0006351 181 0.153
cellular component movement GO:0006928 335 0.152
regulation of nitrogen compound metabolic process GO:0051171 251 0.151
regulation of primary metabolic process GO:0080090 311 0.151
central nervous system development GO:0007417 387 0.150
organic cyclic compound metabolic process GO:1901360 301 0.147
response to external stimulus GO:0009605 264 0.146
hematopoietic or lymphoid organ development GO:0048534 191 0.146
positive regulation of biological process GO:0048518 253 0.126
rna biosynthetic process GO:0032774 181 0.123
phosphorus metabolic process GO:0006793 109 0.119
regulation of autophagy GO:0010506 3 0.118
regulation of metabolic process GO:0019222 359 0.114
regulation of cellular metabolic process GO:0031323 320 0.114
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.113
regulation of macromolecule metabolic process GO:0060255 317 0.107
nucleobase containing compound metabolic process GO:0006139 274 0.107
negative regulation of signal transduction GO:0009968 94 0.103
head development GO:0060322 303 0.101
response to biotic stimulus GO:0009607 97 0.101
cellular nitrogen compound biosynthetic process GO:0044271 218 0.100
regulation of transcription dna templated GO:0006355 213 0.099
cellular response to extracellular stimulus GO:0031668 2 0.090
signal transduction GO:0007165 455 0.088
ameboidal type cell migration GO:0001667 143 0.087
cellular response to external stimulus GO:0071496 2 0.086
convergent extension GO:0060026 118 0.086
nucleobase containing compound biosynthetic process GO:0034654 205 0.085
immune system development GO:0002520 191 0.082
phosphate containing compound metabolic process GO:0006796 108 0.080
digestive tract development GO:0048565 265 0.079
regulation of rna metabolic process GO:0051252 224 0.076
regulation of biological quality GO:0065008 263 0.075
single organism organelle organization GO:1902589 199 0.074
regulation of rna biosynthetic process GO:2001141 213 0.073
organonitrogen compound metabolic process GO:1901564 74 0.072
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.072
response to external biotic stimulus GO:0043207 97 0.072
response to other organism GO:0051707 97 0.072
cellular response to nutrient levels GO:0031669 2 0.072
cognition GO:0050890 1 0.072
locomotion GO:0040011 313 0.071
digestive tract morphogenesis GO:0048546 231 0.071
regulation of nucleic acid templated transcription GO:1903506 213 0.069
immune system process GO:0002376 241 0.068
protein localization to nucleus GO:0034504 3 0.067
cellular aromatic compound metabolic process GO:0006725 295 0.067
multi organism process GO:0051704 134 0.066
regulation of cellular ketone metabolic process GO:0010565 7 0.066
cellular protein catabolic process GO:0044257 4 0.065
maintenance of location GO:0051235 4 0.064
hemopoiesis GO:0030097 183 0.064
negative regulation of cellular process GO:0048523 283 0.062
negative regulation of autophagy GO:0010507 1 0.062
regulation of signal transduction GO:0009966 225 0.062
inositol lipid mediated signaling GO:0048017 2 0.061
negative regulation of signaling GO:0023057 96 0.061
neuron differentiation GO:0030182 353 0.060
epithelial tube morphogenesis GO:0060562 148 0.060
tube morphogenesis GO:0035239 349 0.060
localization of cell GO:0051674 244 0.057
regulation of cellular biosynthetic process GO:0031326 245 0.056
cellular amine metabolic process GO:0044106 2 0.056
positive regulation of cell killing GO:0031343 2 0.056
rna metabolic process GO:0016070 219 0.055
amine metabolic process GO:0009308 2 0.055
response to stress GO:0006950 263 0.054
biosynthetic process GO:0009058 294 0.054
cellular macromolecule metabolic process GO:0044260 391 0.053
liver development GO:0001889 96 0.051
heart development GO:0007507 313 0.051
regulation of cellular amine metabolic process GO:0033238 0 0.050
specification of symmetry GO:0009799 204 0.050
growth GO:0040007 174 0.049
embryonic heart tube development GO:0035050 133 0.049
single organism localization GO:1902578 225 0.049
regulation of response to stimulus GO:0048583 269 0.049
cellular response to starvation GO:0009267 1 0.048
somatic muscle development GO:0007525 4 0.048
phagocytosis GO:0006909 3 0.047
phosphorylation GO:0016310 69 0.047
aging GO:0007568 2 0.047
extrinsic apoptotic signaling pathway GO:0097191 3 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.045
lipid storage GO:0019915 1 0.044
small molecule metabolic process GO:0044281 77 0.043
negative regulation of defense response GO:0031348 2 0.043
single organism metabolic process GO:0044710 217 0.043
cellular ketone metabolic process GO:0042180 11 0.043
cellular protein metabolic process GO:0044267 129 0.042
intracellular signal transduction GO:0035556 85 0.042
determination of left right symmetry GO:0007368 179 0.042
erythrocyte homeostasis GO:0034101 55 0.042
homeostatic process GO:0042592 142 0.041
synaptic target recognition GO:0008039 1 0.041
protein metabolic process GO:0019538 183 0.040
negative regulation of response to stimulus GO:0048585 104 0.040
organic substance biosynthetic process GO:1901576 289 0.040
embryonic organ morphogenesis GO:0048562 274 0.040
morphogenesis of an epithelium GO:0002009 333 0.039
multicellular organism growth GO:0035264 4 0.039
developmental cell growth GO:0048588 52 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.039
positive regulation of cellular process GO:0048522 201 0.039
negative regulation of metabolic process GO:0009892 86 0.039
nucleic acid templated transcription GO:0097659 181 0.039
nuclear transport GO:0051169 4 0.038
heart morphogenesis GO:0003007 156 0.038
rna transport GO:0050658 2 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
protein import GO:0017038 3 0.037
generation of neurons GO:0048699 385 0.037
regulation of protein catabolic process GO:0042176 1 0.037
defense response GO:0006952 47 0.037
developmental growth GO:0048589 166 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.036
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.036
myeloid cell differentiation GO:0030099 86 0.035
brain development GO:0007420 293 0.035
digestive system development GO:0055123 289 0.035
negative regulation of cellular metabolic process GO:0031324 77 0.035
nucleocytoplasmic transport GO:0006913 4 0.035
embryonic organ development GO:0048568 381 0.035
regulation of cytokine production GO:0001817 3 0.034
negative regulation of cell communication GO:0010648 96 0.033
regulation of signaling GO:0023051 235 0.033
transport GO:0006810 220 0.033
regulation of phosphorus metabolic process GO:0051174 43 0.033
positive regulation of gene expression GO:0010628 71 0.033
determination of bilateral symmetry GO:0009855 204 0.033
macroautophagy GO:0016236 1 0.033
establishment of localization GO:0051234 244 0.033
single organism nuclear import GO:1902593 3 0.032
muscle organ development GO:0007517 101 0.032
neuron neuron synaptic transmission GO:0007270 1 0.032
regulation of developmental process GO:0050793 247 0.032
organelle organization GO:0006996 227 0.032
protein modification process GO:0036211 100 0.031
axis elongation GO:0003401 31 0.031
organophosphate metabolic process GO:0019637 37 0.031
gland development GO:0048732 143 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
homeostasis of number of cells GO:0048872 62 0.030
hormone transport GO:0009914 2 0.029
regulation of nervous system development GO:0051960 90 0.029
oxoacid metabolic process GO:0043436 31 0.029
cell substrate adhesion GO:0031589 4 0.028
enzyme linked receptor protein signaling pathway GO:0007167 106 0.028
cellular response to organic substance GO:0071310 105 0.028
response to bacterium GO:0009617 58 0.028
phosphatidylinositol mediated signaling GO:0048015 2 0.027
programmed cell death GO:0012501 119 0.027
response to hexose GO:0009746 3 0.027
immune effector process GO:0002252 23 0.026
cell motility GO:0048870 244 0.026
cell killing GO:0001906 2 0.026
muscle structure development GO:0061061 196 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
regulation of multicellular organismal development GO:2000026 223 0.026
endosomal transport GO:0016197 2 0.026
regulation of bone mineralization GO:0030500 2 0.025
macromolecule modification GO:0043412 111 0.025
developmental growth involved in morphogenesis GO:0060560 86 0.025
regulation of cell killing GO:0031341 2 0.025
single organism transport GO:0044765 206 0.025
nucleotide metabolic process GO:0009117 28 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.024
g protein coupled receptor signaling pathway GO:0007186 74 0.024
connective tissue development GO:0061448 99 0.024
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.024
cell morphogenesis GO:0000902 289 0.023
actin filament based movement GO:0030048 1 0.023
regulation of immune system process GO:0002682 34 0.023
regulation of response to extracellular stimulus GO:0032104 1 0.023
cellular amino acid metabolic process GO:0006520 7 0.022
negative regulation of rna biosynthetic process GO:1902679 45 0.022
positive regulation of transport GO:0051050 2 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
regulation of defense response to virus GO:0050688 2 0.022
regulation of reproductive process GO:2000241 4 0.022
outflow tract morphogenesis GO:0003151 1 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
cellular response to growth factor stimulus GO:0071363 39 0.022
gastrulation GO:0007369 208 0.021
nucleic acid metabolic process GO:0090304 244 0.021
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.021
regulation of rac protein signal transduction GO:0035020 1 0.021
leukocyte activation GO:0045321 12 0.021
cell death GO:0008219 121 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
regionalization GO:0003002 274 0.021
response to light stimulus GO:0009416 46 0.020
response to glucose GO:0009749 3 0.020
peptide transport GO:0015833 1 0.020
cellular component biogenesis GO:0044085 178 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
positive regulation of immune effector process GO:0002699 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
heart looping GO:0001947 94 0.020
neuromuscular process controlling balance GO:0050885 3 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of cell differentiation GO:0045595 142 0.020
myeloid cell homeostasis GO:0002262 56 0.019
protein dephosphorylation GO:0006470 3 0.019
embryonic limb morphogenesis GO:0030326 2 0.019
cell growth GO:0016049 57 0.019
convergent extension involved in axis elongation GO:0060028 26 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
sequestering of calcium ion GO:0051208 3 0.019
chordate embryonic development GO:0043009 271 0.019
cell projection organization GO:0030030 284 0.019
regulation of growth GO:0040008 42 0.019
regulation of synaptic plasticity GO:0048167 1 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
compound eye development GO:0048749 2 0.018
defense response to virus GO:0051607 10 0.018
cell migration GO:0016477 237 0.018
system process GO:0003008 185 0.018
death GO:0016265 121 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
cellular transition metal ion homeostasis GO:0046916 3 0.018
regulation of cell development GO:0060284 100 0.017
response to chemical GO:0042221 320 0.017
cellular protein modification process GO:0006464 100 0.017
muscle tissue development GO:0060537 110 0.017
erythrocyte differentiation GO:0030218 54 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
primary neural tube formation GO:0014020 1 0.017
regulation of neurogenesis GO:0050767 87 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
female gonad development GO:0008585 4 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
vasculature development GO:0001944 278 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
non canonical wnt signaling pathway GO:0035567 13 0.017
positive regulation of cellular biosynthetic process GO:0031328 68 0.017
multicellular organismal metabolic process GO:0044236 2 0.016
hindbrain development GO:0030902 91 0.016
leukocyte mediated cytotoxicity GO:0001909 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
neuron projection guidance GO:0097485 86 0.016
regulation of cell communication GO:0010646 232 0.016
regulation of response to nutrient levels GO:0032107 1 0.016
ribosomal small subunit biogenesis GO:0042274 2 0.016
regulation of locomotion GO:0040012 55 0.016
inorganic cation transmembrane transport GO:0098662 50 0.016
protein import into nucleus GO:0006606 3 0.016
negative regulation of catabolic process GO:0009895 3 0.016
protein targeting to nucleus GO:0044744 3 0.016
positive regulation of rac protein signal transduction GO:0035022 1 0.016
nuclear import GO:0051170 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
positive regulation of catabolic process GO:0009896 4 0.015
response to monosaccharide GO:0034284 3 0.015
organic acid metabolic process GO:0006082 31 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
positive regulation of rna metabolic process GO:0051254 59 0.015
somite development GO:0061053 96 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
glutamate receptor signaling pathway GO:0007215 1 0.015
regulation of epidermis development GO:0045682 2 0.015
carbohydrate homeostasis GO:0033500 1 0.014
entrainment of circadian clock by photoperiod GO:0043153 1 0.014
germ line stem cell maintenance GO:0030718 2 0.014
membrane organization GO:0061024 21 0.014
regulation of hormone secretion GO:0046883 2 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
cell part morphogenesis GO:0032990 246 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
neuron projection morphogenesis GO:0048812 161 0.014
regulation of defense response GO:0031347 14 0.014
cytokinesis GO:0000910 3 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
endocrine hormone secretion GO:0060986 2 0.013
iron ion homeostasis GO:0055072 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
regulation of molecular function GO:0065009 70 0.013
negative regulation of blood circulation GO:1903523 2 0.013
regulation of blood circulation GO:1903522 32 0.013
regulation of cellular component size GO:0032535 30 0.013
insulin like growth factor receptor signaling pathway GO:0048009 4 0.013
chemotaxis GO:0006935 104 0.013
regulation of localization GO:0032879 104 0.013
response to radiation GO:0009314 51 0.013
myeloid cell development GO:0061515 32 0.013
blood circulation GO:0008015 87 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of growth rate GO:0040009 1 0.012
hormone secretion GO:0046879 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.012
response to abiotic stimulus GO:0009628 122 0.012
mononuclear cell proliferation GO:0032943 1 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
neuron development GO:0048666 262 0.012
hepaticobiliary system development GO:0061008 98 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
response to wounding GO:0009611 116 0.011
rho protein signal transduction GO:0007266 5 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
camera type eye morphogenesis GO:0048593 108 0.011
regulation of erythrocyte differentiation GO:0045646 2 0.011
negative regulation of kinase activity GO:0033673 4 0.011
phagocytosis engulfment GO:0006911 1 0.011
establishment of localization in cell GO:0051649 77 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
transition metal ion homeostasis GO:0055076 5 0.011
golgi vesicle transport GO:0048193 3 0.011
negative regulation of gene expression GO:0010629 65 0.011
cell projection morphogenesis GO:0048858 244 0.011
membrane invagination GO:0010324 1 0.011
sequestering of metal ion GO:0051238 3 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
positive regulation of oocyte development GO:0060282 1 0.011
taxis GO:0042330 109 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
negative regulation of wnt signaling pathway GO:0030178 30 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
lipid metabolic process GO:0006629 52 0.011
neuron projection development GO:0031175 180 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
gonadotropin secretion GO:0032274 1 0.011
gtp metabolic process GO:0046039 4 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
cellular response to hypoxia GO:0071456 1 0.010
cell aging GO:0007569 2 0.010
regulation of transporter activity GO:0032409 2 0.010
positive regulation of cell division GO:0051781 2 0.010
regulation of protein metabolic process GO:0051246 56 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
regulation of extent of cell growth GO:0061387 29 0.010
axon development GO:0061564 166 0.010
exocytosis GO:0006887 1 0.010
female sex differentiation GO:0046660 4 0.010
mitotic cell cycle GO:0000278 64 0.010
meiotic nuclear division GO:0007126 4 0.010
regulation of phosphate metabolic process GO:0019220 43 0.010
cell migration involved in gastrulation GO:0042074 79 0.010
regulation of tube size GO:0035150 2 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010

prkar1aa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
breast cancer DOID:1612 0 0.016
thoracic cancer DOID:5093 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
amyloidosis DOID:9120 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
urinary system cancer DOID:3996 0 0.012