Danio rerio

0 known processes

mtpn

myotrophin

(Aliases: zgc:64078,wu:fa10f07)

mtpn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.118
proteasomal protein catabolic process GO:0010498 2 0.091
maintenance of location GO:0051235 4 0.089
signal transduction GO:0007165 455 0.078
amine metabolic process GO:0009308 2 0.078
larval development GO:0002164 2 0.078
meiotic nuclear division GO:0007126 4 0.074
positive regulation of transport GO:0051050 2 0.072
phagocytosis GO:0006909 3 0.068
response to stress GO:0006950 263 0.065
regulation of biological quality GO:0065008 263 0.062
Human
cellular amine metabolic process GO:0044106 2 0.061
single organism metabolic process GO:0044710 217 0.060
single organism localization GO:1902578 225 0.059
negative regulation of protein complex assembly GO:0031333 1 0.059
Human
lipid storage GO:0019915 1 0.055
ubiquitin dependent protein catabolic process GO:0006511 3 0.053
regulation of protein complex assembly GO:0043254 3 0.053
Human
aging GO:0007568 2 0.050
cell projection organization GO:0030030 284 0.050
endosomal transport GO:0016197 2 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.047
response to chemical GO:0042221 320 0.045
protein polymerization GO:0051258 4 0.044
meiotic chromosome segregation GO:0045132 3 0.042
modification dependent protein catabolic process GO:0019941 3 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
regulation of protein polymerization GO:0032271 2 0.037
Human
establishment of localization GO:0051234 244 0.036
negative regulation of nuclear division GO:0051784 3 0.035
organelle fusion GO:0048284 3 0.035
negative regulation of biological process GO:0048519 304 0.035
Human
organelle organization GO:0006996 227 0.034
transport GO:0006810 220 0.034
single organism nuclear import GO:1902593 3 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.032
regulation of cellular metabolic process GO:0031323 320 0.032
hematopoietic or lymphoid organ development GO:0048534 191 0.032
cell morphogenesis GO:0000902 289 0.032
protein metabolic process GO:0019538 183 0.032
cellular protein catabolic process GO:0044257 4 0.032
cell cycle GO:0007049 93 0.031
cellular protein modification process GO:0006464 100 0.031
negative regulation of cellular process GO:0048523 283 0.031
Human
cellular response to external stimulus GO:0071496 2 0.031
regulation of filopodium assembly GO:0051489 2 0.030
single organism transport GO:0044765 206 0.030
phosphorus metabolic process GO:0006793 109 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
single fertilization GO:0007338 3 0.029
cellular protein metabolic process GO:0044267 129 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
compound eye development GO:0048749 2 0.028
regulation of primary metabolic process GO:0080090 311 0.028
intracellular signal transduction GO:0035556 85 0.027
cellular component morphogenesis GO:0032989 336 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
positive regulation of catabolic process GO:0009896 4 0.027
cellular ketone metabolic process GO:0042180 11 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
regulation of protein catabolic process GO:0042176 1 0.026
homeostatic process GO:0042592 142 0.026
cellular component biogenesis GO:0044085 178 0.026
membrane fusion GO:0061025 2 0.025
organic acid metabolic process GO:0006082 31 0.025
locomotion GO:0040011 313 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
gtp catabolic process GO:0006184 2 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
protein polyubiquitination GO:0000209 4 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
macromolecular complex disassembly GO:0032984 1 0.025
small molecule metabolic process GO:0044281 77 0.025
protein complex disassembly GO:0043241 1 0.025
regulation of cell shape GO:0008360 1 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
oxoacid metabolic process GO:0043436 31 0.024
positive regulation of cell cycle GO:0045787 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
nuclear import GO:0051170 3 0.024
neuron projection morphogenesis GO:0048812 161 0.024
regulation of metal ion transport GO:0010959 4 0.023
cellular component disassembly GO:0022411 1 0.023
regulation of synapse assembly GO:0051963 3 0.023
protein targeting to nucleus GO:0044744 3 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
nucleocytoplasmic transport GO:0006913 4 0.022
metal ion transport GO:0030001 58 0.022
meiotic cell cycle process GO:1903046 3 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
cellular response to nutrient levels GO:0031669 2 0.022
regulation of binding GO:0051098 3 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
actin polymerization or depolymerization GO:0008154 2 0.021
regulation of localization GO:0032879 104 0.021
immune system process GO:0002376 241 0.021
biosynthetic process GO:0009058 294 0.021
cell migration GO:0016477 237 0.021
regulation of signal transduction GO:0009966 225 0.021
regulation of cell projection assembly GO:0060491 4 0.021
rna localization GO:0006403 4 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
regulation of protein transport GO:0051223 3 0.020
rna biosynthetic process GO:0032774 181 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
vacuolar transport GO:0007034 2 0.020
autophagy GO:0006914 4 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
stem cell proliferation GO:0072089 4 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
transmembrane transport GO:0055085 120 0.020
lamellipodium organization GO:0097581 1 0.019
regulation of gene expression GO:0010468 265 0.019
cell part morphogenesis GO:0032990 246 0.019
regulation of reproductive process GO:2000241 4 0.019
hemopoiesis GO:0030097 183 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
transcription dna templated GO:0006351 181 0.019
nuclear transport GO:0051169 4 0.019
response to external stimulus GO:0009605 264 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
regulation of protein complex disassembly GO:0043244 1 0.019
Human
immune system development GO:0002520 191 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
cellular localization GO:0051641 97 0.019
cell projection morphogenesis GO:0048858 244 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
death GO:0016265 121 0.019
cell death GO:0008219 121 0.018
response to drug GO:0042493 3 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
cellular component assembly GO:0022607 170 0.018
chordate embryonic development GO:0043009 271 0.018
gene expression GO:0010467 252 0.018
spermatid development GO:0007286 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
actin filament polymerization GO:0030041 2 0.018
neuroblast proliferation GO:0007405 2 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
gtp metabolic process GO:0046039 4 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of oocyte development GO:0060281 3 0.017
regulation of molecular function GO:0065009 70 0.017
positive regulation of biological process GO:0048518 253 0.017
Human
organic substance biosynthetic process GO:1901576 289 0.017
stem cell maintenance GO:0019827 4 0.017
protein import GO:0017038 3 0.017
neuron differentiation GO:0030182 353 0.017
single organism membrane fusion GO:0044801 2 0.017
regulation of signaling GO:0023051 235 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
phagocytosis engulfment GO:0006911 1 0.017
single organism organelle organization GO:1902589 199 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
heterocycle metabolic process GO:0046483 290 0.016
apoptotic process involved in development GO:1902742 2 0.016
regulation of transport GO:0051049 45 0.016
regulation of circadian rhythm GO:0042752 4 0.016
regulation of chromosome segregation GO:0051983 1 0.016
generation of neurons GO:0048699 385 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
membrane invagination GO:0010324 1 0.016
protein import into nucleus GO:0006606 3 0.016
cytoplasm organization GO:0007028 4 0.016
cellular response to starvation GO:0009267 1 0.016
apoptotic process GO:0006915 116 0.016
pronuclear migration GO:0035046 1 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
synaptic vesicle recycling GO:0036465 1 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
lamellipodium assembly GO:0030032 1 0.016
multi organism process GO:0051704 134 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
cellular response to extracellular stimulus GO:0031668 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
protein localization to plasma membrane GO:0072659 1 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
regulation of cytokine production GO:0001817 3 0.015
regulation of protein depolymerization GO:1901879 1 0.015
Human
organism emergence from protective structure GO:0071684 4 0.015
protein localization to nucleus GO:0034504 3 0.015
spindle assembly GO:0051225 2 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of protein metabolic process GO:0051246 56 0.015
post golgi vesicle mediated transport GO:0006892 1 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of calcium ion transport GO:0051924 2 0.015
adherens junction organization GO:0034332 4 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
cellular biosynthetic process GO:0044249 286 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of cell activation GO:0050865 1 0.015
protein localization GO:0008104 40 0.014
regulation of catalytic activity GO:0050790 55 0.014
pole plasm assembly GO:0007315 4 0.014
adult behavior GO:0030534 2 0.014
ion transmembrane transport GO:0034220 91 0.014
regulation of response to stimulus GO:0048583 269 0.014
Human
oocyte anterior posterior axis specification GO:0007314 4 0.014
protein modification process GO:0036211 100 0.014
female meiotic division GO:0007143 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
organelle assembly GO:0070925 110 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
establishment of localization in cell GO:0051649 77 0.014
macromolecule modification GO:0043412 111 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
peptidyl serine modification GO:0018209 2 0.014
regulation of transporter activity GO:0032409 2 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
protein depolymerization GO:0051261 1 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
cellular response to stress GO:0033554 62 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
protein complex biogenesis GO:0070271 30 0.013
stem cell division GO:0017145 1 0.013
mitochondrion organization GO:0007005 4 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
nucleic acid transport GO:0050657 2 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
fertilization GO:0009566 3 0.013
regulation of cell communication GO:0010646 232 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
organelle localization GO:0051640 49 0.013
golgi vesicle transport GO:0048193 3 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.012
regulation of receptor mediated endocytosis GO:0048259 4 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
synaptic vesicle transport GO:0048489 1 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
establishment of rna localization GO:0051236 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
cellular component movement GO:0006928 335 0.012
primary neural tube formation GO:0014020 1 0.012
centrosome organization GO:0051297 1 0.012
specification of axis polarity GO:0065001 4 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
digestive system development GO:0055123 289 0.012
neuron projection development GO:0031175 180 0.012
regulation of apoptotic process GO:0042981 98 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
chromatin organization GO:0006325 22 0.012
spermatid differentiation GO:0048515 2 0.012
protein secretion GO:0009306 1 0.012
multicellular organism growth GO:0035264 4 0.012
leukocyte proliferation GO:0070661 1 0.012
determination of left right symmetry GO:0007368 179 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
macromolecule localization GO:0033036 54 0.012
protein stabilization GO:0050821 2 0.012
regulation of protein binding GO:0043393 3 0.012
nuclear export GO:0051168 1 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
regulation of biosynthetic process GO:0009889 250 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
atp catabolic process GO:0006200 4 0.011
cytoskeleton organization GO:0007010 96 0.011
developmental programmed cell death GO:0010623 4 0.011
protein dephosphorylation GO:0006470 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
nucleobase containing compound transport GO:0015931 2 0.011
response to hydrogen peroxide GO:0042542 3 0.011
nuclear migration GO:0007097 3 0.011
positive regulation of cell activation GO:0050867 1 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
mitotic cell cycle GO:0000278 64 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
erythrocyte homeostasis GO:0034101 55 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
system process GO:0003008 185 0.011
Human
carbohydrate biosynthetic process GO:0016051 1 0.011
exocytosis GO:0006887 1 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
peptidyl threonine modification GO:0018210 1 0.011
negative regulation of defense response GO:0031348 2 0.011
dna templated transcription elongation GO:0006354 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
positive regulation of reproductive process GO:2000243 2 0.011
hatching GO:0035188 4 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
cation transport GO:0006812 81 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.010
tube closure GO:0060606 1 0.010
centrosome cycle GO:0007098 1 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
microtubule based process GO:0007017 60 0.010
peptide transport GO:0015833 1 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
cytokinesis GO:0000910 3 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
rna metabolic process GO:0016070 219 0.010
response to glucose GO:0009749 3 0.010
sleep GO:0030431 1 0.010
axon development GO:0061564 166 0.010
rna transport GO:0050658 2 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
erythrocyte differentiation GO:0030218 54 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
female gonad development GO:0008585 4 0.010
microtubule organizing center organization GO:0031023 1 0.010

mtpn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012