Danio rerio

28 known processes

lbr

lamin B receptor

(Aliases: wu:fb75h08,zgc:86649,wu:fc47b04,wu:fd36b07,sb:cb406)

lbr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular metabolic process GO:0031323 320 0.417
cellular macromolecule biosynthetic process GO:0034645 224 0.412
cellular biosynthetic process GO:0044249 286 0.378
nucleobase containing compound metabolic process GO:0006139 274 0.352
regulation of nucleic acid templated transcription GO:1903506 213 0.302
organic cyclic compound metabolic process GO:1901360 301 0.297
signal transduction GO:0007165 455 0.287
cell projection organization GO:0030030 284 0.287
regulation of nitrogen compound metabolic process GO:0051171 251 0.278
regulation of biosynthetic process GO:0009889 250 0.261
cell proliferation GO:0008283 80 0.248
nucleic acid metabolic process GO:0090304 244 0.247
macromolecule biosynthetic process GO:0009059 227 0.244
cellular macromolecule metabolic process GO:0044260 391 0.242
regulation of macromolecule metabolic process GO:0060255 317 0.227
axon development GO:0061564 166 0.216
aging GO:0007568 2 0.209
biosynthetic process GO:0009058 294 0.208
negative regulation of biological process GO:0048519 304 0.202
neuron differentiation GO:0030182 353 0.198
larval development GO:0002164 2 0.193
organic substance biosynthetic process GO:1901576 289 0.180
heterocycle biosynthetic process GO:0018130 215 0.177
nucleobase containing compound biosynthetic process GO:0034654 205 0.176
regulation of macromolecule biosynthetic process GO:0010556 225 0.175
heterocycle metabolic process GO:0046483 290 0.164
regulation of primary metabolic process GO:0080090 311 0.164
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.162
regulation of rna biosynthetic process GO:2001141 213 0.154
negative regulation of cellular process GO:0048523 283 0.151
regulation of rna metabolic process GO:0051252 224 0.150
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.143
positive regulation of map kinase activity GO:0043406 3 0.142
aromatic compound biosynthetic process GO:0019438 217 0.134
nucleic acid templated transcription GO:0097659 181 0.126
head development GO:0060322 303 0.119
cellular component morphogenesis GO:0032989 336 0.118
regulation of cellular biosynthetic process GO:0031326 245 0.112
negative regulation of ras protein signal transduction GO:0046580 1 0.111
cellular nitrogen compound biosynthetic process GO:0044271 218 0.101
cell motility GO:0048870 244 0.099
single organism metabolic process GO:0044710 217 0.098
axonogenesis GO:0007409 152 0.097
localization of cell GO:0051674 244 0.097
gene expression GO:0010467 252 0.097
regulation of gene expression GO:0010468 265 0.095
nitrogen compound metabolic process GO:0006807 319 0.095
stem cell proliferation GO:0072089 4 0.093
negative regulation of rna metabolic process GO:0051253 48 0.092
generation of neurons GO:0048699 385 0.083
sensory organ development GO:0007423 393 0.082
stem cell maintenance GO:0019827 4 0.081
cell morphogenesis involved in differentiation GO:0000904 195 0.081
stem cell differentiation GO:0048863 117 0.081
regulation of transcription dna templated GO:0006355 213 0.081
cellular nitrogen compound metabolic process GO:0034641 290 0.080
ras protein signal transduction GO:0007265 7 0.078
central nervous system development GO:0007417 387 0.077
negative regulation of cellular metabolic process GO:0031324 77 0.076
death GO:0016265 121 0.071
regulation of metabolic process GO:0019222 359 0.070
response to chemical GO:0042221 320 0.070
transcription dna templated GO:0006351 181 0.069
brain development GO:0007420 293 0.068
apoptotic process GO:0006915 116 0.066
cell projection morphogenesis GO:0048858 244 0.066
regulation of signaling GO:0023051 235 0.066
cellular component movement GO:0006928 335 0.065
cellular protein modification process GO:0006464 100 0.065
regulation of cell communication GO:0010646 232 0.063
organelle organization GO:0006996 227 0.061
rna biosynthetic process GO:0032774 181 0.061
neuron development GO:0048666 262 0.060
stem cell division GO:0017145 1 0.059
protein modification process GO:0036211 100 0.058
macromolecule modification GO:0043412 111 0.056
negative regulation of metabolic process GO:0009892 86 0.056
chordate embryonic development GO:0043009 271 0.055
regulation of nucleotide catabolic process GO:0030811 2 0.055
intracellular signal transduction GO:0035556 85 0.055
cellular response to lipopolysaccharide GO:0071222 3 0.051
phagocytosis GO:0006909 3 0.050
positive regulation of cell cycle GO:0045787 3 0.050
multi organism process GO:0051704 134 0.049
cell morphogenesis GO:0000902 289 0.049
negative regulation of gene expression GO:0010629 65 0.049
rna metabolic process GO:0016070 219 0.048
hepaticobiliary system development GO:0061008 98 0.048
cellular response to molecule of bacterial origin GO:0071219 3 0.047
regulation of intracellular signal transduction GO:1902531 57 0.047
hindbrain development GO:0030902 91 0.047
growth GO:0040007 174 0.046
negative regulation of cellular biosynthetic process GO:0031327 55 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.045
regulation of dna replication GO:0006275 3 0.045
cell death GO:0008219 121 0.044
embryonic skeletal system development GO:0048706 97 0.044
regulation of mrna processing GO:0050684 3 0.043
striated muscle cell differentiation GO:0051146 129 0.043
protein metabolic process GO:0019538 183 0.043
regulation of biological quality GO:0065008 263 0.043
muscle cell development GO:0055001 115 0.043
regulation of binding GO:0051098 3 0.042
cilium morphogenesis GO:0060271 85 0.042
small gtpase mediated signal transduction GO:0007264 8 0.042
negative regulation of macromolecule metabolic process GO:0010605 76 0.041
nucleic acid transport GO:0050657 2 0.040
cell migration GO:0016477 237 0.039
regulation of multicellular organism growth GO:0040014 4 0.038
cell cycle process GO:0022402 53 0.038
regulation of cellular component organization GO:0051128 86 0.038
positive regulation of nucleoside metabolic process GO:0045979 1 0.038
lateral inhibition GO:0046331 1 0.037
stem cell fate commitment GO:0048865 1 0.037
cell part morphogenesis GO:0032990 246 0.037
programmed cell death GO:0012501 119 0.035
cellular response to chemical stimulus GO:0070887 157 0.035
rna localization GO:0006403 4 0.034
meiotic cell cycle process GO:1903046 3 0.034
centrosome organization GO:0051297 1 0.034
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
cellular component biogenesis GO:0044085 178 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
regulation of production of molecular mediator of immune response GO:0002700 1 0.032
cellular component disassembly GO:0022411 1 0.032
negative regulation of transcription dna templated GO:0045892 45 0.032
single organism biosynthetic process GO:0044711 71 0.032
regulation of response to stimulus GO:0048583 269 0.031
hemopoiesis GO:0030097 183 0.031
immune system process GO:0002376 241 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
positive regulation of nucleotide catabolic process GO:0030813 1 0.030
maintenance of location GO:0051235 4 0.030
positive regulation of immune effector process GO:0002699 3 0.030
rna transport GO:0050658 2 0.030
positive regulation of catabolic process GO:0009896 4 0.030
single organism organelle organization GO:1902589 199 0.030
negative regulation of signaling GO:0023057 96 0.030
positive regulation of gtpase activity GO:0043547 1 0.029
regulation of catalytic activity GO:0050790 55 0.029
regulation of signal transduction GO:0009966 225 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.029
organic acid metabolic process GO:0006082 31 0.029
neuroblast proliferation GO:0007405 2 0.029
regionalization GO:0003002 274 0.029
cell cycle GO:0007049 93 0.028
organelle assembly GO:0070925 110 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.028
negative regulation of dna metabolic process GO:0051053 4 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
response to wounding GO:0009611 116 0.028
regulation of developmental process GO:0050793 247 0.028
camera type eye morphogenesis GO:0048593 108 0.028
multicellular organism growth GO:0035264 4 0.028
chemotaxis GO:0006935 104 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
pancreas development GO:0031016 84 0.026
epithelial cell differentiation GO:0030855 116 0.026
positive regulation of gtp catabolic process GO:0033126 1 0.026
connective tissue development GO:0061448 99 0.026
cellular protein metabolic process GO:0044267 129 0.026
regulation of stem cell proliferation GO:0072091 2 0.025
retinoic acid receptor signaling pathway GO:0048384 16 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
locomotion GO:0040011 313 0.025
response to uv GO:0009411 3 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
stem cell development GO:0048864 82 0.025
female gonad development GO:0008585 4 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
regulation of protein complex assembly GO:0043254 3 0.025
cytoskeleton organization GO:0007010 96 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
regulation of protein transport GO:0051223 3 0.024
sensory organ morphogenesis GO:0090596 200 0.024
meiotic spindle organization GO:0000212 1 0.024
regeneration GO:0031099 91 0.024
microtubule cytoskeleton organization GO:0000226 33 0.023
lipid storage GO:0019915 1 0.023
regulation of cell shape GO:0008360 1 0.023
protein polymerization GO:0051258 4 0.023
chromosome organization GO:0051276 31 0.023
muscle structure development GO:0061061 196 0.023
liver development GO:0001889 96 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
neuron projection morphogenesis GO:0048812 161 0.022
myofibril assembly GO:0030239 48 0.022
regulation of cell activation GO:0050865 1 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
oxoacid metabolic process GO:0043436 31 0.022
response to lipid GO:0033993 60 0.022
negative regulation of signal transduction GO:0009968 94 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
gland development GO:0048732 143 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
oocyte maturation GO:0001556 4 0.022
negative regulation of nucleic acid templated transcription GO:1903507 45 0.021
circulatory system process GO:0003013 87 0.021
response to organic substance GO:0010033 153 0.021
translational initiation GO:0006413 3 0.021
nuclear transport GO:0051169 4 0.021
regulation of phosphate metabolic process GO:0019220 43 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
histone modification GO:0016570 20 0.021
camera type eye development GO:0043010 222 0.021
establishment of rna localization GO:0051236 3 0.021
actomyosin structure organization GO:0031032 53 0.020
inner ear development GO:0048839 126 0.020
b cell activation GO:0042113 2 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
ear development GO:0043583 127 0.020
response to hydrogen peroxide GO:0042542 3 0.020
cellular localization GO:0051641 97 0.020
cytokinesis GO:0000910 3 0.020
negative regulation of protein kinase activity GO:0006469 4 0.019
negative regulation of histone methylation GO:0031061 1 0.019
epidermis development GO:0008544 48 0.019
digestive tract development GO:0048565 265 0.019
meiosis i GO:0007127 1 0.019
regulation of dendrite development GO:0050773 3 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
phagocytosis engulfment GO:0006911 1 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
protein complex disassembly GO:0043241 1 0.019
retina development in camera type eye GO:0060041 146 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
striated muscle cell development GO:0055002 108 0.018
meiotic nuclear division GO:0007126 4 0.018
regulation of cytokine production GO:0001817 3 0.018
negative regulation of kinase activity GO:0033673 4 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
regulation of epithelial to mesenchymal transition GO:0010717 3 0.018
positive regulation of cellular process GO:0048522 201 0.018
positive regulation of developmental process GO:0051094 50 0.018
microtubule organizing center organization GO:0031023 1 0.017
regulation of cell development GO:0060284 100 0.017
positive regulation of cell activation GO:0050867 1 0.017
protein acetylation GO:0006473 2 0.017
positive regulation of metabolic process GO:0009893 108 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
cardiac atrium morphogenesis GO:0003209 2 0.017
regulation of cell differentiation GO:0045595 142 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
positive regulation of transport GO:0051050 2 0.017
regulation of cell proliferation GO:0042127 37 0.016
mesenchyme development GO:0060485 127 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
neuron projection development GO:0031175 180 0.016
cellular response to organic substance GO:0071310 105 0.016
heart contraction GO:0060047 71 0.016
response to stress GO:0006950 263 0.016
eye development GO:0001654 277 0.016
response to other organism GO:0051707 97 0.016
positive regulation of catalytic activity GO:0043085 25 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
positive regulation of biological process GO:0048518 253 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
regulation of nucleotide metabolic process GO:0006140 17 0.016
heart process GO:0003015 71 0.016
response to biotic stimulus GO:0009607 97 0.016
negative regulation of cell communication GO:0010648 96 0.015
dna metabolic process GO:0006259 27 0.015
embryonic limb morphogenesis GO:0030326 2 0.015
neuroblast fate commitment GO:0014017 1 0.015
response to endogenous stimulus GO:0009719 83 0.015
mrna transport GO:0051028 2 0.015
blood circulation GO:0008015 87 0.015
regulation of gtpase activity GO:0043087 2 0.015
response to external stimulus GO:0009605 264 0.015
nuclear envelope organization GO:0006998 2 0.015
regulation of chromosome segregation GO:0051983 1 0.015
macromolecular complex disassembly GO:0032984 1 0.015
embryonic cranial skeleton morphogenesis GO:0048701 90 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
negative regulation of protein complex assembly GO:0031333 1 0.015
regulation of protein binding GO:0043393 3 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
negative regulation of histone modification GO:0031057 1 0.015
male meiosis GO:0007140 2 0.015
somatic cell dna recombination GO:0016444 1 0.015
nucleobase containing compound transport GO:0015931 2 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
developmental growth GO:0048589 166 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
dna templated transcription elongation GO:0006354 3 0.014
regulation of immune response GO:0050776 14 0.014
eye morphogenesis GO:0048592 144 0.014
cellular amine metabolic process GO:0044106 2 0.014
zymogen activation GO:0031638 3 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
convergent extension involved in gastrulation GO:0060027 71 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
protein dephosphorylation GO:0006470 3 0.013
regulation of protein catabolic process GO:0042176 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
regulation of apoptotic process GO:0042981 98 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
skeletal system development GO:0001501 181 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
mesenchymal cell development GO:0014031 78 0.013
response to drug GO:0042493 3 0.013
positive regulation of histone modification GO:0031058 1 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
immunoglobulin production GO:0002377 1 0.013
centrosome cycle GO:0007098 1 0.013
transport GO:0006810 220 0.013
establishment of endothelial barrier GO:0061028 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
cartilage condensation GO:0001502 3 0.013
dna methylation on cytosine GO:0032776 3 0.013
single organism localization GO:1902578 225 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
regulation of molecular function GO:0065009 70 0.013
regulation of epidermis development GO:0045682 2 0.013
response to external biotic stimulus GO:0043207 97 0.013
regulation of protein metabolic process GO:0051246 56 0.013
tube closure GO:0060606 1 0.012
protein complex subunit organization GO:0071822 46 0.012
microtubule based process GO:0007017 60 0.012
cellular macromolecular complex assembly GO:0034622 24 0.012
spermatid differentiation GO:0048515 2 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
proximal distal pattern formation GO:0009954 1 0.012
axon guidance GO:0007411 86 0.012
cell proliferation in forebrain GO:0021846 3 0.012
chromatin modification GO:0016568 21 0.012
cell fate specification GO:0001708 68 0.012
amine metabolic process GO:0009308 2 0.012
positive regulation of programmed cell death GO:0043068 29 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
phosphorus metabolic process GO:0006793 109 0.012
positive regulation of carbohydrate metabolic process GO:0045913 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
lipid metabolic process GO:0006629 52 0.012
positive regulation of cell differentiation GO:0045597 30 0.012
cilium organization GO:0044782 71 0.012
positive regulation of phosphorus metabolic process GO:0010562 21 0.012
developmental process involved in reproduction GO:0003006 27 0.012
negative regulation of chromatin modification GO:1903309 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
digestive tract morphogenesis GO:0048546 231 0.012
carbohydrate biosynthetic process GO:0016051 1 0.011
cell fate commitment GO:0045165 99 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
negative regulation of catabolic process GO:0009895 3 0.011
chromatin organization GO:0006325 22 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
b cell differentiation GO:0030183 1 0.011
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.011
negative regulation of muscle cell differentiation GO:0051148 1 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
vasculature development GO:0001944 278 0.011
intracellular receptor signaling pathway GO:0030522 30 0.011
protein complex localization GO:0031503 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
innervation GO:0060384 3 0.011
regulation of heart contraction GO:0008016 32 0.011
muscle cell differentiation GO:0042692 139 0.011
taxis GO:0042330 109 0.011
mitochondrion organization GO:0007005 4 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
positive regulation of ras gtpase activity GO:0032320 1 0.011
regulation of programmed cell death GO:0043067 101 0.011
embryonic organ development GO:0048568 381 0.010
regulation of cell death GO:0010941 103 0.010
regulation of transferase activity GO:0051338 16 0.010
centrosome duplication GO:0051298 1 0.010
mitotic cell cycle embryonic GO:0045448 2 0.010
regulation of gene expression epigenetic GO:0040029 11 0.010
radial glial cell differentiation GO:0060019 2 0.010
cardiac atrium development GO:0003230 4 0.010
metencephalon development GO:0022037 27 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
midbrain development GO:0030901 28 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.010
regulation of protein polymerization GO:0032271 2 0.010
tissue regeneration GO:0042246 74 0.010
b cell mediated immunity GO:0019724 3 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
carbohydrate derivative metabolic process GO:1901135 61 0.010
rna stabilization GO:0043489 4 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010

lbr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of cellular proliferation DOID:14566 0 0.011
physical disorder DOID:0080015 0 0.011