Danio rerio

36 known processes

dvl2

dishevelled, dsh homolog 2 (Drosophila)

(Aliases: wu:fp54a02,wu:fc05d12,wu:fo71e09,zgc:55372)

dvl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of jun kinase activity GO:0043507 2 0.707
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.606
Human Mouse
positive regulation of jnk cascade GO:0046330 3 0.555
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.420
Human Mouse
response to external stimulus GO:0009605 264 0.391
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.331
Human
regulation of signal transduction GO:0009966 225 0.258
Human Mouse Fly
rna biosynthetic process GO:0032774 181 0.251
Human
regulation of cellular metabolic process GO:0031323 320 0.216
Human Mouse
larval development GO:0002164 2 0.216
Worm
central nervous system development GO:0007417 387 0.184
regulation of response to stimulus GO:0048583 269 0.170
Human Mouse Fly
regulation of signaling GO:0023051 235 0.167
Human Mouse Fly
negative regulation of signal transduction GO:0009968 94 0.154
Fly
response to stress GO:0006950 263 0.153
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.152
Human
convergent extension GO:0060026 118 0.152
cell morphogenesis GO:0000902 289 0.151
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.151
Human Mouse Worm
positive regulation of map kinase activity GO:0043406 3 0.142
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.141
Human
digestive tract morphogenesis GO:0048546 231 0.139
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.135
Human
regulation of metabolic process GO:0019222 359 0.131
Human Mouse Worm
regulation of cell communication GO:0010646 232 0.126
Human Mouse Fly
positive regulation of biological process GO:0048518 253 0.123
Human Mouse Fly
cell part morphogenesis GO:0032990 246 0.119
Fly
single organism organelle organization GO:1902589 199 0.116
Worm Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.115
regulation of cellular biosynthetic process GO:0031326 245 0.111
Human
head development GO:0060322 303 0.107
stem cell maintenance GO:0019827 4 0.107
Fly
positive regulation of signal transduction GO:0009967 56 0.106
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.104
Human
positive regulation of cell communication GO:0010647 56 0.103
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.102
Human Zebrafish Mouse Worm Fly
regulation of stem cell differentiation GO:2000736 4 0.101
Fly
blood vessel development GO:0001568 246 0.099
wnt signaling pathway GO:0016055 80 0.099
Human Zebrafish Mouse Worm Fly
digestive system development GO:0055123 289 0.098
Worm
cellular response to extracellular stimulus GO:0031668 2 0.097
regulation of jun kinase activity GO:0043506 3 0.097
Human Mouse
negative regulation of response to stimulus GO:0048585 104 0.096
Fly
negative regulation of cell communication GO:0010648 96 0.094
Fly
regulation of biosynthetic process GO:0009889 250 0.092
Human
cellular response to stress GO:0033554 62 0.091
Human Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.090
Fly
cellular component morphogenesis GO:0032989 336 0.089
Fly
neuron projection development GO:0031175 180 0.089
Fly
heart development GO:0007507 313 0.085
Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.084
Human
positive regulation of signaling GO:0023056 56 0.084
Human Mouse
developmental growth GO:0048589 166 0.083
female sex differentiation GO:0046660 4 0.082
Fly
rna metabolic process GO:0016070 219 0.082
Human
cellular macromolecule metabolic process GO:0044260 391 0.081
Human Mouse
proteasomal protein catabolic process GO:0010498 2 0.080
lamellipodium assembly GO:0030032 1 0.080
Fly
positive regulation of response to stimulus GO:0048584 80 0.080
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.079
Human
regulation of meiotic cell cycle GO:0051445 1 0.079
cell substrate adhesion GO:0031589 4 0.077
cellular response to starvation GO:0009267 1 0.077
negative regulation of biological process GO:0048519 304 0.077
Fly
gene expression GO:0010467 252 0.076
Human
nuclear transport GO:0051169 4 0.073
cellular protein catabolic process GO:0044257 4 0.071
cellular response to external stimulus GO:0071496 2 0.070
cellular nitrogen compound biosynthetic process GO:0044271 218 0.069
Human
cellular response to nutrient levels GO:0031669 2 0.068
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.068
heart morphogenesis GO:0003007 156 0.067
Mouse Fly
positive regulation of cellular process GO:0048522 201 0.067
Human Mouse
organelle organization GO:0006996 227 0.066
Worm Fly
macromolecule biosynthetic process GO:0009059 227 0.066
Human
negative regulation of cellular process GO:0048523 283 0.066
Fly
lamellipodium organization GO:0097581 1 0.064
Fly
epithelial cell differentiation GO:0030855 116 0.063
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.062
Human
cardiac cell fate commitment GO:0060911 1 0.061
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.061
Human
regulation of multicellular organism growth GO:0040014 4 0.060
aging GO:0007568 2 0.060
phosphate containing compound metabolic process GO:0006796 108 0.060
Human Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.060
nucleic acid metabolic process GO:0090304 244 0.059
Human
response to chemical GO:0042221 320 0.059
Fly
protein targeting to nucleus GO:0044744 3 0.059
cellular component movement GO:0006928 335 0.059
modification dependent protein catabolic process GO:0019941 3 0.058
meiotic nuclear division GO:0007126 4 0.058
phosphorus metabolic process GO:0006793 109 0.057
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.057
Human
regulation of transcription dna templated GO:0006355 213 0.056
Human
signal transduction GO:0007165 455 0.054
Human Zebrafish Mouse Worm Fly
death GO:0016265 121 0.054
cellular biosynthetic process GO:0044249 286 0.054
Human
autophagy GO:0006914 4 0.054
neuron projection extension GO:1990138 45 0.053
Fly
single organism nuclear import GO:1902593 3 0.053
somatic stem cell maintenance GO:0035019 1 0.052
Fly
phosphorylation GO:0016310 69 0.052
Human Mouse
activation of mapk activity GO:0000187 3 0.052
cell migration GO:0016477 237 0.052
lipid storage GO:0019915 1 0.051
modification dependent macromolecule catabolic process GO:0043632 3 0.051
positive regulation of cellular catabolic process GO:0031331 3 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.051
intracellular signal transduction GO:0035556 85 0.050
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.050
Human
gastrulation GO:0007369 208 0.050
Worm
angiogenesis GO:0001525 158 0.050
specification of organ identity GO:0010092 2 0.050
post anal tail morphogenesis GO:0036342 19 0.049
specification of symmetry GO:0009799 204 0.049
developmental growth involved in morphogenesis GO:0060560 86 0.049
ubiquitin dependent protein catabolic process GO:0006511 3 0.048
neuron differentiation GO:0030182 353 0.048
Fly
positive regulation of metabolic process GO:0009893 108 0.047
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.047
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.047
cell projection assembly GO:0030031 64 0.047
Fly
regulation of cellular protein catabolic process GO:1903362 1 0.046
establishment of protein localization to organelle GO:0072594 4 0.046
embryonic organ development GO:0048568 381 0.046
Mouse
regulation of establishment of protein localization GO:0070201 4 0.046
cellular component assembly GO:0022607 170 0.046
Fly
regeneration GO:0031099 91 0.046
macroautophagy GO:0016236 1 0.046
gland development GO:0048732 143 0.045
Fly
tube morphogenesis GO:0035239 349 0.045
Mouse Worm
locomotion GO:0040011 313 0.045
nucleobase containing compound metabolic process GO:0006139 274 0.044
Human
positive regulation of macromolecule metabolic process GO:0010604 93 0.044
Human Mouse
synaptic target recognition GO:0008039 1 0.044
Fly
dorsal ventral pattern formation GO:0009953 125 0.044
cellular response to chemical stimulus GO:0070887 157 0.044
axon extension GO:0048675 45 0.043
Fly
cell projection morphogenesis GO:0048858 244 0.043
Fly
regulation of gene expression GO:0010468 265 0.042
Human Worm
regulation of protein catabolic process GO:0042176 1 0.042
regulation of mrna splicing via spliceosome GO:0048024 3 0.042
positive regulation of catabolic process GO:0009896 4 0.042
regulation of cell shape GO:0008360 1 0.042
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.041
protein metabolic process GO:0019538 183 0.041
Human Mouse
protein localization to nucleus GO:0034504 3 0.040
cellular macromolecule biosynthetic process GO:0034645 224 0.040
Human
regionalization GO:0003002 274 0.040
Mouse Fly
localization of cell GO:0051674 244 0.040
axon development GO:0061564 166 0.039
Fly
digestive tract development GO:0048565 265 0.039
Worm
single organism metabolic process GO:0044710 217 0.039
Human Mouse
negative chemotaxis GO:0050919 1 0.039
Fly
protein import into nucleus GO:0006606 3 0.038
cell motility GO:0048870 244 0.038
extrinsic apoptotic signaling pathway GO:0097191 3 0.037
positive regulation of dna metabolic process GO:0051054 1 0.037
taxis GO:0042330 109 0.037
Fly
heart field specification GO:0003128 1 0.037
neuron development GO:0048666 262 0.036
Fly
regulation of primary metabolic process GO:0080090 311 0.036
Human Mouse
generation of neurons GO:0048699 385 0.036
Worm Fly
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.036
Fly
aromatic compound biosynthetic process GO:0019438 217 0.036
Human
vasculature development GO:0001944 278 0.036
nucleic acid templated transcription GO:0097659 181 0.036
Human
negative regulation of cellular catabolic process GO:0031330 3 0.036
establishment of localization GO:0051234 244 0.035
Worm
cellular response to organic substance GO:0071310 105 0.035
positive regulation of rna metabolic process GO:0051254 59 0.035
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.035
regulation of glucose import GO:0046324 1 0.034
response to drug GO:0042493 3 0.034
multi organism process GO:0051704 134 0.034
Worm Fly
blood vessel morphogenesis GO:0048514 216 0.034
determination of bilateral symmetry GO:0009855 204 0.034
response to nutrient GO:0007584 3 0.033
sensory organ development GO:0007423 393 0.033
Mouse Fly
phagocytosis GO:0006909 3 0.033
positive regulation of cell adhesion GO:0045785 1 0.032
growth GO:0040007 174 0.032
negative regulation of signaling GO:0023057 96 0.032
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.032
Human
axon regeneration GO:0031103 14 0.032
heterocycle metabolic process GO:0046483 290 0.032
Human
regulation of response to cytokine stimulus GO:0060759 3 0.032
morphogenesis of an epithelium GO:0002009 333 0.031
regulation of protein transport GO:0051223 3 0.031
regulation of chromosome segregation GO:0051983 1 0.030
regulation of catalytic activity GO:0050790 55 0.030
Human Mouse
biosynthetic process GO:0009058 294 0.030
Human
establishment of apical basal cell polarity GO:0035089 2 0.029
Fly
regulation of response to nutrient levels GO:0032107 1 0.029
negative regulation of cell differentiation GO:0045596 46 0.029
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.029
nuclear import GO:0051170 3 0.029
immune system process GO:0002376 241 0.029
dna biosynthetic process GO:0071897 3 0.029
axon guidance GO:0007411 86 0.028
Fly
negative regulation of multicellular organismal process GO:0051241 69 0.028
Fly
embryonic organ morphogenesis GO:0048562 274 0.028
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.028
Human
negative regulation of stem cell differentiation GO:2000737 2 0.027
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
Human Mouse Worm Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
translational initiation GO:0006413 3 0.027
erythrocyte differentiation GO:0030218 54 0.027
stem cell fate commitment GO:0048865 1 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
regulation of binding GO:0051098 3 0.026
regulation of phosphorus metabolic process GO:0051174 43 0.026
Human Mouse
epithelial tube morphogenesis GO:0060562 148 0.026
Mouse
cell matrix adhesion GO:0007160 4 0.025
cell morphogenesis involved in differentiation GO:0000904 195 0.025
Fly
glucose import GO:0046323 2 0.025
protein modification process GO:0036211 100 0.025
Human Mouse
response to wounding GO:0009611 116 0.025
protein import GO:0017038 3 0.025
mesenchymal cell differentiation GO:0048762 87 0.025
regulation of proteolysis GO:0030162 24 0.025
tissue regeneration GO:0042246 74 0.025
cellular localization GO:0051641 97 0.025
Mouse Worm
cytosolic calcium ion transport GO:0060401 3 0.025
programmed cell death GO:0012501 119 0.024
embryonic skeletal joint development GO:0072498 3 0.024
cellular response to endogenous stimulus GO:0071495 68 0.024
regulation of autophagy GO:0010506 3 0.024
response to external biotic stimulus GO:0043207 97 0.024
regulation of cytokine production GO:0001817 3 0.024
neuroblast differentiation GO:0014016 1 0.024
regulation of cellular response to growth factor stimulus GO:0090287 35 0.024
brain development GO:0007420 293 0.024
transcription dna templated GO:0006351 181 0.023
Human
erk1 and erk2 cascade GO:0070371 4 0.023
regulation of protein targeting GO:1903533 2 0.023
neuron projection regeneration GO:0031102 16 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
microtubule based process GO:0007017 60 0.023
Worm
biological adhesion GO:0022610 40 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
Human
multicellular organism growth GO:0035264 4 0.023
determination of left right symmetry GO:0007368 179 0.023
positive regulation of cellular metabolic process GO:0031325 94 0.023
Human Mouse
maintenance of location GO:0051235 4 0.023
establishment of monopolar cell polarity GO:0061162 2 0.023
Fly
regulation of neural precursor cell proliferation GO:2000177 3 0.022
cell migration involved in gastrulation GO:0042074 79 0.022
regulation of phosphorylation GO:0042325 26 0.022
Human Mouse
regulation of cellular component movement GO:0051270 55 0.022
formation of primary germ layer GO:0001704 62 0.022
Worm
positive regulation of transport GO:0051050 2 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
cellular response to lipopolysaccharide GO:0071222 3 0.022
actin filament bundle assembly GO:0051017 6 0.022
Fly
mesenchyme development GO:0060485 127 0.022
single organism localization GO:1902578 225 0.021
Worm
sex determination GO:0007530 1 0.021
regulation of cell substrate adhesion GO:0010810 1 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
regulation of cell matrix adhesion GO:0001952 1 0.021
endoderm development GO:0007492 49 0.021
Worm
regulation of developmental process GO:0050793 247 0.021
Human Mouse Worm Fly
regulation of establishment of planar polarity GO:0090175 4 0.021
Human Mouse Worm
muscle structure development GO:0061061 196 0.021
establishment of epithelial cell polarity GO:0090162 2 0.021
Fly
body morphogenesis GO:0010171 16 0.021
Worm
peptidyl serine phosphorylation GO:0018105 1 0.020
regulation of intracellular signal transduction GO:1902531 57 0.020
Human Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.020
non canonical wnt signaling pathway GO:0035567 13 0.020
Human Mouse Worm
regulation of cellular response to stress GO:0080135 20 0.020
Human Mouse
wound healing GO:0042060 90 0.020
positive regulation of programmed cell death GO:0043068 29 0.020
positive regulation of rna biosynthetic process GO:1902680 57 0.020
Human
negative regulation of response to cytokine stimulus GO:0060761 2 0.020
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.020
Fly
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
muscle cell migration GO:0014812 4 0.020
somite development GO:0061053 96 0.020
hemopoiesis GO:0030097 183 0.020
regulation of molecular function GO:0065009 70 0.019
Human Mouse
negative regulation of cytokine production GO:0001818 1 0.019
regulation of protein metabolic process GO:0051246 56 0.019
Human Mouse
chemotaxis GO:0006935 104 0.019
Fly
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.019
cellular protein metabolic process GO:0044267 129 0.019
Human Mouse
regulation of programmed cell death GO:0043067 101 0.019
mitotic cell cycle embryonic GO:0045448 2 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.019
Human
cellular component disassembly GO:0022411 1 0.019
retinal ganglion cell axon guidance GO:0031290 35 0.019
Fly
homeostatic process GO:0042592 142 0.019
meiotic cell cycle process GO:1903046 3 0.018
ameboidal type cell migration GO:0001667 143 0.018
Fly
response to other organism GO:0051707 97 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
Fly
rna 3 end processing GO:0031123 2 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
Human
cell cell signaling involved in cell fate commitment GO:0045168 12 0.018
Fly
cell adhesion GO:0007155 40 0.018
stem cell development GO:0048864 82 0.018
Fly
cellular protein modification process GO:0006464 100 0.018
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
Human Mouse Worm Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.018
Human
regulation of intracellular protein transport GO:0033157 3 0.018
mesenchymal cell development GO:0014031 78 0.018
cellular response to growth factor stimulus GO:0071363 39 0.018
mrna stabilization GO:0048255 4 0.017
myeloid cell differentiation GO:0030099 86 0.017
regulation of microtubule cytoskeleton organization GO:0070507 3 0.017
Worm
regulation of response to external stimulus GO:0032101 31 0.017
cellular component biogenesis GO:0044085 178 0.017
Fly
regulation of cell activation GO:0050865 1 0.017
muscle cell differentiation GO:0042692 139 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 6 0.017
Human Mouse
cell cycle g1 s phase transition GO:0044843 1 0.017
stem cell differentiation GO:0048863 117 0.017
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.017
Mouse Worm Fly
sequestering of metal ion GO:0051238 3 0.017
regulation of mapk cascade GO:0043408 14 0.017
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.017
regulation of cellular component organization GO:0051128 86 0.017
Worm Fly
cellular response to biotic stimulus GO:0071216 3 0.017
amine metabolic process GO:0009308 2 0.017
response to growth factor GO:0070848 39 0.017
regulation of cell death GO:0010941 103 0.017
regulation of jak stat cascade GO:0046425 3 0.017
regulation of cell cycle GO:0051726 52 0.017
Worm
regulation of rna metabolic process GO:0051252 224 0.016
Human
regulation of protein binding GO:0043393 3 0.016
regulation of biological quality GO:0065008 263 0.016
Fly
regulation of stem cell proliferation GO:0072091 2 0.016
regulation of jnk cascade GO:0046328 5 0.016
Human Mouse
skin development GO:0043588 54 0.016
Worm Fly
cell recognition GO:0008037 19 0.016
Fly
sexual reproduction GO:0019953 36 0.016
Fly
response to biotic stimulus GO:0009607 97 0.016
glial cell proliferation GO:0014009 4 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
eye development GO:0001654 277 0.016
Fly
axis elongation GO:0003401 31 0.016
regulation of organelle assembly GO:1902115 4 0.016
axonogenesis GO:0007409 152 0.016
Fly
homeostasis of number of cells GO:0048872 62 0.016
activation of jun kinase activity GO:0007257 2 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
epiboly GO:0090504 41 0.016
spindle assembly GO:0051225 2 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
Fly
negative regulation of dna metabolic process GO:0051053 4 0.016
regulation of dna replication GO:0006275 3 0.015
outflow tract morphogenesis GO:0003151 1 0.015
Mouse
female gonad development GO:0008585 4 0.015
Fly
meiosis i GO:0007127 1 0.015
membrane invagination GO:0010324 1 0.015
positive regulation of cytokine production GO:0001819 2 0.015
neuron projection guidance GO:0097485 86 0.015
Fly
calcium ion transport into cytosol GO:0060402 3 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
macromolecule modification GO:0043412 111 0.015
Human Mouse
positive regulation of protein complex assembly GO:0031334 2 0.015
hepaticobiliary system development GO:0061008 98 0.015
positive regulation of cell activation GO:0050867 1 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
cognition GO:0050890 1 0.015
defense response to bacterium GO:0042742 22 0.015
inner ear development GO:0048839 126 0.015
Mouse
regulation of organelle organization GO:0033043 29 0.015
Worm Fly
cell cycle GO:0007049 93 0.015
Worm
response to carbohydrate GO:0009743 3 0.015
transport GO:0006810 220 0.015
axon extension involved in axon guidance GO:0048846 10 0.015
negative regulation of ras protein signal transduction GO:0046580 1 0.014
cell death GO:0008219 121 0.014
neuron projection morphogenesis GO:0048812 161 0.014
Fly
cell growth GO:0016049 57 0.014
Fly
regulation of protein complex assembly GO:0043254 3 0.014
cell adhesion mediated by integrin GO:0033627 1 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
negative regulation of catabolic process GO:0009895 3 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
Human
positive regulation of cell killing GO:0031343 2 0.014
regulation of reproductive process GO:2000241 4 0.014
immune system development GO:0002520 191 0.014
actin filament bundle organization GO:0061572 6 0.014
Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
regulation of glucose transport GO:0010827 1 0.014
monocyte differentiation GO:0030224 2 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
Worm Fly
skeletal muscle organ development GO:0060538 78 0.014
negative regulation of myeloid cell differentiation GO:0045638 1 0.014
regulation of apoptotic process GO:0042981 98 0.014
response to organic substance GO:0010033 153 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
cell projection organization GO:0030030 284 0.014
Fly
response to glucose GO:0009749 3 0.014
positive regulation of secretion GO:0051047 1 0.014
pigmentation GO:0043473 85 0.014
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.014
Human
telomere organization GO:0032200 1 0.013
lateral inhibition GO:0046331 1 0.013
system process GO:0003008 185 0.013
negative regulation of translation GO:0017148 1 0.013
response to monosaccharide GO:0034284 3 0.013
lipid homeostasis GO:0055088 3 0.013
striated muscle cell differentiation GO:0051146 129 0.013
olfactory bulb development GO:0021772 4 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
hindbrain development GO:0030902 91 0.013
negative regulation of defense response GO:0031348 2 0.013
cell substrate junction assembly GO:0007044 2 0.013
mrna polyadenylation GO:0006378 2 0.013
energy reserve metabolic process GO:0006112 2 0.013
regulation of translational initiation GO:0006446 1 0.013
ear development GO:0043583 127 0.013
Mouse
rna stabilization GO:0043489 4 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.013
Human Mouse Worm
nucleic acid transport GO:0050657 2 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
Human
reactive oxygen species biosynthetic process GO:1903409 1 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
negative regulation of secretion GO:0051048 2 0.013
response to corticosteroid GO:0031960 1 0.013
chromosome organization GO:0051276 31 0.012
adult behavior GO:0030534 2 0.012
response to abiotic stimulus GO:0009628 122 0.012
protein complex disassembly GO:0043241 1 0.012
striated muscle cell development GO:0055002 108 0.012
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.012
signal transduction by phosphorylation GO:0023014 18 0.012
Human Mouse
behavior GO:0007610 74 0.012
Worm
chemical homeostasis GO:0048878 49 0.012
regulation of kinase activity GO:0043549 15 0.012
Human Mouse
nuclear export GO:0051168 1 0.012
secondary metabolic process GO:0019748 3 0.012
circadian sleep wake cycle GO:0042745 2 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
organelle assembly GO:0070925 110 0.012
response to ketone GO:1901654 1 0.012
regulation of nuclear division GO:0051783 9 0.012
adherens junction assembly GO:0034333 1 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
proteolysis GO:0006508 38 0.012
hypothalamus cell differentiation GO:0021979 4 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
tissue remodeling GO:0048771 4 0.012
cell migration in hindbrain GO:0021535 7 0.012
er nucleus signaling pathway GO:0006984 2 0.012
somitogenesis GO:0001756 87 0.012
regulation of cell migration GO:0030334 40 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
embryonic skeletal system development GO:0048706 97 0.012
positive regulation of developmental process GO:0051094 50 0.011
Fly
organic acid metabolic process GO:0006082 31 0.011
regulation of type i interferon production GO:0032479 2 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
Human
muscle organ development GO:0007517 101 0.011
jnk cascade GO:0007254 7 0.011
Human Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.011
Human Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.011
Worm
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
cell killing GO:0001906 2 0.011
response to uv GO:0009411 3 0.011
glucose homeostasis GO:0042593 1 0.011
stem cell proliferation GO:0072089 4 0.011
heart formation GO:0060914 13 0.011
Fly
response to hydrogen peroxide GO:0042542 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
Human
peptide transport GO:0015833 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
protein dephosphorylation GO:0006470 3 0.011
protein homooligomerization GO:0051260 3 0.011
heart looping GO:0001947 94 0.011
positive regulation of immune effector process GO:0002699 3 0.011
defense response to other organism GO:0098542 33 0.011
erythrocyte homeostasis GO:0034101 55 0.011
response to fluid shear stress GO:0034405 2 0.011
response to topologically incorrect protein GO:0035966 2 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
commissural neuron axon guidance GO:0071679 3 0.011
regulation of synapse assembly GO:0051963 3 0.011

dvl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.050
disease of cellular proliferation DOID:14566 0 0.050
organ system cancer DOID:0050686 0 0.045
disease of anatomical entity DOID:7 0 0.032
musculoskeletal system disease DOID:17 0 0.016