Danio rerio

0 known processes

reln

reelin

reln biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.703
sleep GO:0030431 1 0.648
cognition GO:0050890 1 0.624
central nervous system development GO:0007417 387 0.608
ventral spinal cord development GO:0021517 35 0.509
ion transport GO:0006811 114 0.505
circadian sleep wake cycle sleep GO:0050802 1 0.481
regulation of circadian sleep wake cycle GO:0042749 1 0.479
ion transmembrane transport GO:0034220 91 0.452
locomotion GO:0040011 313 0.449
single organism localization GO:1902578 225 0.447
locomotory behavior GO:0007626 34 0.419
response to alkaloid GO:0043279 2 0.417
regulation of multicellular organismal development GO:2000026 223 0.401
response to chemical GO:0042221 320 0.392
single organism transport GO:0044765 206 0.389
sensory organ development GO:0007423 393 0.372
transmembrane transport GO:0055085 120 0.370
neuron differentiation GO:0030182 353 0.366
cell projection organization GO:0030030 284 0.339
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.338
transport GO:0006810 220 0.317
establishment of localization GO:0051234 244 0.309
response to external stimulus GO:0009605 264 0.288
cell motility GO:0048870 244 0.276
camera type eye development GO:0043010 222 0.275
cell differentiation in spinal cord GO:0021515 40 0.274
negative regulation of lyase activity GO:0051350 6 0.257
neurological system process GO:0050877 62 0.250
eye development GO:0001654 277 0.229
adult behavior GO:0030534 2 0.217
single organism behavior GO:0044708 24 0.189
circadian sleep wake cycle process GO:0022410 2 0.185
cellular component movement GO:0006928 335 0.175
carboxylic acid catabolic process GO:0046395 3 0.174
gene expression GO:0010467 252 0.174
multicellular organism growth GO:0035264 4 0.169
heterocycle biosynthetic process GO:0018130 215 0.158
positive regulation of cellular process GO:0048522 201 0.153
larval development GO:0002164 2 0.151
cell morphogenesis GO:0000902 289 0.149
circadian sleep wake cycle GO:0042745 2 0.148
negative regulation of protein kinase b signaling GO:0051898 2 0.148
neuron development GO:0048666 262 0.147
long chain fatty acid transport GO:0015909 1 0.144
regulation of neurogenesis GO:0050767 87 0.143
cation transport GO:0006812 81 0.143
spinal cord development GO:0021510 46 0.141
negative regulation of camp metabolic process GO:0030815 7 0.132
anion transport GO:0006820 38 0.129
response to amphetamine GO:0001975 1 0.129
female gonad development GO:0008585 4 0.125
inner ear development GO:0048839 126 0.124
signal transduction GO:0007165 455 0.123
system process GO:0003008 185 0.117
localization of cell GO:0051674 244 0.113
regulation of axonogenesis GO:0050770 32 0.104
cell surface receptor signaling pathway GO:0007166 325 0.104
regulation of cell differentiation GO:0045595 142 0.103
regulation of nervous system development GO:0051960 90 0.101
neuron neuron synaptic transmission GO:0007270 1 0.099
regulation of locomotion GO:0040012 55 0.098
positive regulation of biological process GO:0048518 253 0.095
organic cyclic compound metabolic process GO:1901360 301 0.093
head development GO:0060322 303 0.093
organic anion transport GO:0015711 15 0.092
rna biosynthetic process GO:0032774 181 0.092
regulation of rna biosynthetic process GO:2001141 213 0.089
regulation of transmembrane transport GO:0034762 18 0.089
response to drug GO:0042493 3 0.088
negative regulation of gliogenesis GO:0014014 1 0.087
growth GO:0040007 174 0.087
regulation of biological quality GO:0065008 263 0.085
regulation of circadian rhythm GO:0042752 4 0.084
brain development GO:0007420 293 0.084
negative regulation of purine nucleotide biosynthetic process GO:1900372 7 0.083
neuron projection morphogenesis GO:0048812 161 0.083
cell migration GO:0016477 237 0.083
transcription dna templated GO:0006351 181 0.082
positive regulation of developmental process GO:0051094 50 0.082
positive regulation of transport GO:0051050 2 0.080
cellular macromolecule metabolic process GO:0044260 391 0.079
embryonic organ development GO:0048568 381 0.078
response to food GO:0032094 1 0.076
regulation of cell projection organization GO:0031344 44 0.075
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.075
meiotic nuclear division GO:0007126 4 0.072
behavior GO:0007610 74 0.071
neuron projection development GO:0031175 180 0.061
heterocycle metabolic process GO:0046483 290 0.061
cell morphogenesis involved in differentiation GO:0000904 195 0.060
lipid catabolic process GO:0016042 4 0.060
sensory perception GO:0007600 39 0.057
ventral spinal cord interneuron differentiation GO:0021514 12 0.056
regulation of macromolecule biosynthetic process GO:0010556 225 0.056
regulation of transcription dna templated GO:0006355 213 0.056
cellular aromatic compound metabolic process GO:0006725 295 0.056
cellular component assembly GO:0022607 170 0.055
regulation of developmental process GO:0050793 247 0.055
regulation of gene expression GO:0010468 265 0.054
regulation of metal ion transport GO:0010959 4 0.054
nucleic acid templated transcription GO:0097659 181 0.053
negative regulation of camp biosynthetic process GO:0030818 7 0.053
regulation of cell morphogenesis GO:0022604 42 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.051
maintenance of location GO:0051235 4 0.051
negative regulation of metabolic process GO:0009892 86 0.051
cellular component morphogenesis GO:0032989 336 0.050
positive regulation of cell differentiation GO:0045597 30 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
neurotransmitter transport GO:0006836 2 0.048
axon development GO:0061564 166 0.048
organic substance biosynthetic process GO:1901576 289 0.048
carboxylic acid transport GO:0046942 8 0.047
regulation of transport GO:0051049 45 0.047
regulation of multicellular organismal process GO:0051239 277 0.046
cellular nitrogen compound biosynthetic process GO:0044271 218 0.045
stem cell differentiation GO:0048863 117 0.045
positive regulation of multicellular organismal process GO:0051240 52 0.044
cellular biosynthetic process GO:0044249 286 0.043
response to osmotic stress GO:0006970 11 0.042
neuroblast proliferation GO:0007405 2 0.041
angiogenesis GO:0001525 158 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
organic substance transport GO:0071702 58 0.040
cellular response to organic substance GO:0071310 105 0.040
regulation of transmembrane transporter activity GO:0022898 2 0.040
negative regulation of cellular process GO:0048523 283 0.040
aging GO:0007568 2 0.038
cell projection morphogenesis GO:0048858 244 0.038
regulation of nucleic acid templated transcription GO:1903506 213 0.038
regulation of neuronal synaptic plasticity GO:0048168 1 0.038
regulation of protein complex assembly GO:0043254 3 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
central nervous system neuron differentiation GO:0021953 74 0.037
small molecule catabolic process GO:0044282 3 0.037
negative regulation of catabolic process GO:0009895 3 0.036
organic acid transport GO:0015849 9 0.036
single organism biosynthetic process GO:0044711 71 0.036
regulation of cellular component organization GO:0051128 86 0.036
neural precursor cell proliferation GO:0061351 20 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.035
cellular lipid catabolic process GO:0044242 3 0.035
response to light stimulus GO:0009416 46 0.035
appendage development GO:0048736 80 0.034
astrocyte differentiation GO:0048708 1 0.034
negative regulation of cellular metabolic process GO:0031324 77 0.034
cation transmembrane transport GO:0098655 65 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.032
response to endogenous stimulus GO:0009719 83 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
gliogenesis GO:0042063 45 0.032
rna metabolic process GO:0016070 219 0.032
post embryonic organ morphogenesis GO:0048563 1 0.032
regulation of multicellular organism growth GO:0040014 4 0.031
cellular response to hormone stimulus GO:0032870 39 0.031
inorganic ion transmembrane transport GO:0098660 57 0.031
regulation of biosynthetic process GO:0009889 250 0.030
positive regulation of cell cycle GO:0045787 3 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
monoamine transport GO:0015844 1 0.030
biosynthetic process GO:0009058 294 0.029
neuron fate commitment GO:0048663 26 0.029
neuron fate specification GO:0048665 20 0.029
developmental cell growth GO:0048588 52 0.029
transcription from rna polymerase ii promoter GO:0006366 80 0.029
negative regulation of adenylate cyclase activity GO:0007194 6 0.028
developmental growth GO:0048589 166 0.028
regulation of metabolic process GO:0019222 359 0.028
muscle structure development GO:0061061 196 0.027
cranial nerve development GO:0021545 42 0.027
positive regulation of non canonical wnt signaling pathway GO:2000052 3 0.027
regulation of camp biosynthetic process GO:0030817 9 0.027
ear development GO:0043583 127 0.027
circadian rhythm GO:0007623 19 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.026
fatty acid transport GO:0015908 1 0.026
reproductive process GO:0022414 40 0.026
developmental programmed cell death GO:0010623 4 0.026
metal ion transport GO:0030001 58 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
cellular component biogenesis GO:0044085 178 0.025
spinal cord motor neuron differentiation GO:0021522 26 0.025
inorganic cation transmembrane transport GO:0098662 50 0.024
oxoacid metabolic process GO:0043436 31 0.024
regulation of anatomical structure morphogenesis GO:0022603 130 0.024
regulation of sequestering of calcium ion GO:0051282 4 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
stem cell proliferation GO:0072089 4 0.024
blood vessel morphogenesis GO:0048514 216 0.023
cell migration in hindbrain GO:0021535 7 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
autophagy GO:0006914 4 0.023
organelle organization GO:0006996 227 0.022
rhythmic process GO:0048511 21 0.022
response to abiotic stimulus GO:0009628 122 0.022
regulation of localization GO:0032879 104 0.022
digestive system development GO:0055123 289 0.022
regulation of growth GO:0040008 42 0.022
regulation of cell development GO:0060284 100 0.022
sensory perception of chemical stimulus GO:0007606 3 0.021
otolith formation GO:0032475 2 0.021
positive regulation of cell development GO:0010720 25 0.021
regulation of blood pressure GO:0008217 1 0.021
axon guidance GO:0007411 86 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
rhythmic behavior GO:0007622 5 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
response to hormone GO:0009725 48 0.021
monovalent inorganic cation transport GO:0015672 42 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
embryonic skeletal joint development GO:0072498 3 0.020
regulation of cell communication GO:0010646 232 0.020
g protein coupled receptor signaling pathway GO:0007186 74 0.019
regulation of ion transport GO:0043269 22 0.019
macromolecule localization GO:0033036 54 0.019
regulation of rna metabolic process GO:0051252 224 0.019
blood vessel development GO:0001568 246 0.019
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.019
thermosensory behavior GO:0040040 1 0.019
skeletal system morphogenesis GO:0048705 102 0.019
protein secretion GO:0009306 1 0.019
response to amine GO:0014075 1 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
negative regulation of biological process GO:0048519 304 0.019
hatching GO:0035188 4 0.019
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
hindbrain development GO:0030902 91 0.018
negative regulation of phosphorus metabolic process GO:0010563 13 0.018
negative regulation of phosphate metabolic process GO:0045936 13 0.018
forebrain anterior posterior pattern specification GO:0021797 3 0.018
negative regulation of multicellular organismal process GO:0051241 69 0.017
response to stress GO:0006950 263 0.017
synaptic transmission GO:0007268 35 0.017
mechanosensory behavior GO:0007638 2 0.017
chordate embryonic development GO:0043009 271 0.017
female sex differentiation GO:0046660 4 0.017
negative regulation of signaling GO:0023057 96 0.017
regulation of exocytosis GO:0017157 1 0.017
regulation of fatty acid beta oxidation GO:0031998 1 0.016
fin development GO:0033333 77 0.016
positive regulation of nervous system development GO:0051962 25 0.016
apoptotic process involved in development GO:1902742 2 0.016
chemical homeostasis GO:0048878 49 0.016
regulation of signal transduction GO:0009966 225 0.016
response to biotic stimulus GO:0009607 97 0.016
epithelial cell development GO:0002064 42 0.016
heart development GO:0007507 313 0.016
skeletal system development GO:0001501 181 0.016
chemotaxis GO:0006935 104 0.016
ventral spinal cord interneuron specification GO:0021521 3 0.016
chemosensory behavior GO:0007635 1 0.015
ear morphogenesis GO:0042471 64 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.015
nitric oxide metabolic process GO:0046209 2 0.015
terpenoid catabolic process GO:0016115 2 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
regulation of signaling GO:0023051 235 0.015
fat soluble vitamin catabolic process GO:0042363 2 0.015
striated muscle cell development GO:0055002 108 0.015
nitrogen compound transport GO:0071705 23 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
response to alcohol GO:0097305 14 0.014
cell part morphogenesis GO:0032990 246 0.014
negative regulation of behavior GO:0048521 6 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
digestive tract development GO:0048565 265 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
morphogenesis of embryonic epithelium GO:0016331 30 0.014
neurotransmitter biosynthetic process GO:0042136 2 0.014
response to nicotine GO:0035094 2 0.014
dopamine metabolic process GO:0042417 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
lateral line development GO:0048882 66 0.013
negative regulation of cell communication GO:0010648 96 0.013
response to corticosteroid GO:0031960 1 0.013
nucleic acid metabolic process GO:0090304 244 0.013
nuclear division GO:0000280 23 0.013
negative regulation of intracellular signal transduction GO:1902532 22 0.013
regulation of mesoderm development GO:2000380 11 0.013
retina development in camera type eye GO:0060041 146 0.013
negative regulation of secretion GO:0051048 2 0.013
hemopoiesis GO:0030097 183 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
regulation of non canonical wnt signaling pathway GO:2000050 7 0.013
protein metabolic process GO:0019538 183 0.013
negative regulation of developmental process GO:0051093 65 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
response to steroid hormone GO:0048545 35 0.013
receptor internalization GO:0031623 2 0.013
organic acid catabolic process GO:0016054 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of blood vessel size GO:0050880 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
positive regulation of neuron migration GO:2001224 2 0.012
regulation of cellular component movement GO:0051270 55 0.012
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.012
apoptotic process GO:0006915 116 0.012
regulation of cellular component size GO:0032535 30 0.012
negative regulation of protein transport GO:0051224 3 0.012
organic acid metabolic process GO:0006082 31 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
cellular response to estrogen stimulus GO:0071391 24 0.012
forebrain development GO:0030900 96 0.012
regulation of anatomical structure size GO:0090066 33 0.012
post embryonic organ development GO:0048569 4 0.012
protein modification process GO:0036211 100 0.012
small molecule metabolic process GO:0044281 77 0.012
calcium ion transport GO:0006816 18 0.012
multi organism process GO:0051704 134 0.011
abducens nerve development GO:0021560 1 0.011
oligodendrocyte differentiation GO:0048709 23 0.011
cell growth GO:0016049 57 0.011
positive regulation of secretion GO:0051047 1 0.011
intracellular estrogen receptor signaling pathway GO:0030520 3 0.011
positive regulation of neurogenesis GO:0050769 24 0.011
response to glucocorticoid GO:0051384 1 0.011
embryonic skeletal system development GO:0048706 97 0.011
forebrain cell migration GO:0021885 1 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
regulation of cellular response to drug GO:2001038 1 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
positive regulation of signaling GO:0023056 56 0.011
negative regulation of feeding behavior GO:2000252 2 0.010
cellular response to toxic substance GO:0097237 1 0.010
regulation of autophagy GO:0010506 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
peptide transport GO:0015833 1 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
cellular response to vitamin a GO:0071299 1 0.010
regulation of protein transport GO:0051223 3 0.010

reln disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
bone development disease DOID:0080006 0 0.019
bone disease DOID:0080001 0 0.019
acrocephalosyndactylia DOID:12960 0 0.019
dysostosis DOID:1934 0 0.019
musculoskeletal system disease DOID:17 0 0.019
connective tissue disease DOID:65 0 0.019
synostosis DOID:11971 0 0.019
pfeiffer syndrome DOID:14705 0 0.016
congenital heart disease DOID:1682 0 0.013
heart septal defect DOID:1681 0 0.013
atrioventricular septal defect DOID:0050651 0 0.013
heart disease DOID:114 0 0.013
cardiovascular system disease DOID:1287 0 0.013
syndrome DOID:225 0 0.011
tooth and nail syndrome DOID:6678 0 0.011