Danio rerio

0 known processes

leprel2

leprecan-like 2

(Aliases: si:ch211-69g19.4)

leprel2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular component biogenesis GO:0044089 3 0.152
regulation of synapse organization GO:0050807 3 0.106
aging GO:0007568 2 0.091
larval development GO:0002164 2 0.087
regulation of synapse assembly GO:0051963 3 0.079
regulation of multicellular organism growth GO:0040014 4 0.068
response to stress GO:0006950 263 0.052
multicellular organism growth GO:0035264 4 0.050
maintenance of location GO:0051235 4 0.047
regulation of metabolic process GO:0019222 359 0.045
lipid storage GO:0019915 1 0.045
stem cell proliferation GO:0072089 4 0.043
positive regulation of catabolic process GO:0009896 4 0.042
determination of bilateral symmetry GO:0009855 204 0.040
cell surface receptor signaling pathway GO:0007166 325 0.040
morphogenesis of an epithelium GO:0002009 333 0.038
cellular response to nutrient levels GO:0031669 2 0.037
regulation of developmental process GO:0050793 247 0.037
digestive tract development GO:0048565 265 0.037
regulation of multicellular organismal development GO:2000026 223 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.033
regulation of reproductive process GO:2000241 4 0.032
developmental growth GO:0048589 166 0.032
positive regulation of protein complex assembly GO:0031334 2 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
cellular response to external stimulus GO:0071496 2 0.031
growth GO:0040007 174 0.031
tube morphogenesis GO:0035239 349 0.031
specification of symmetry GO:0009799 204 0.031
axon development GO:0061564 166 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
gtp catabolic process GO:0006184 2 0.031
signal transduction GO:0007165 455 0.031
cellular component movement GO:0006928 335 0.031
regulation of biological quality GO:0065008 263 0.030
actin polymerization or depolymerization GO:0008154 2 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
response to carbohydrate GO:0009743 3 0.029
cellular macromolecule metabolic process GO:0044260 391 0.029
cellular component morphogenesis GO:0032989 336 0.029
determination of left right symmetry GO:0007368 179 0.029
autophagy GO:0006914 4 0.029
phagocytosis GO:0006909 3 0.029
head development GO:0060322 303 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of cell differentiation GO:0045595 142 0.027
response to monosaccharide GO:0034284 3 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
positive regulation of transport GO:0051050 2 0.027
cell morphogenesis GO:0000902 289 0.027
cellular modified amino acid metabolic process GO:0006575 3 0.026
digestive system development GO:0055123 289 0.026
regulation of cell projection assembly GO:0060491 4 0.026
cellular response to starvation GO:0009267 1 0.026
neuron projection morphogenesis GO:0048812 161 0.026
cellular biosynthetic process GO:0044249 286 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.025
negative regulation of cellular process GO:0048523 283 0.025
central nervous system development GO:0007417 387 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.024
convergent extension GO:0060026 118 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
gtp metabolic process GO:0046039 4 0.024
response to organic substance GO:0010033 153 0.024
neuroblast proliferation GO:0007405 2 0.024
protein complex disassembly GO:0043241 1 0.023
oxoacid metabolic process GO:0043436 31 0.023
regulation of protein polymerization GO:0032271 2 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
response to corticosteroid GO:0031960 1 0.023
amine metabolic process GO:0009308 2 0.023
single organism localization GO:1902578 225 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
response to hexose GO:0009746 3 0.023
embryonic heart tube development GO:0035050 133 0.023
cellular carbohydrate metabolic process GO:0044262 4 0.023
eye development GO:0001654 277 0.023
protein polymerization GO:0051258 4 0.022
response to glucose GO:0009749 3 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
nuclear transport GO:0051169 4 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
response to external stimulus GO:0009605 264 0.022
regulation of protein transport GO:0051223 3 0.022
adult behavior GO:0030534 2 0.022
positive regulation of synapse assembly GO:0051965 1 0.022
protein metabolic process GO:0019538 183 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
mitochondrion organization GO:0007005 4 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
response to chemical GO:0042221 320 0.021
cognition GO:0050890 1 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
single organism membrane fusion GO:0044801 2 0.021
regulation of protein complex assembly GO:0043254 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
neuron development GO:0048666 262 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
alpha amino acid metabolic process GO:1901605 3 0.020
negative regulation of biological process GO:0048519 304 0.020
multicellular organismal metabolic process GO:0044236 2 0.020
locomotion GO:0040011 313 0.020
muscle structure development GO:0061061 196 0.020
cell projection morphogenesis GO:0048858 244 0.020
response to glucocorticoid GO:0051384 1 0.020
macromolecular complex disassembly GO:0032984 1 0.020
cellular amine metabolic process GO:0044106 2 0.019
nucleic acid metabolic process GO:0090304 244 0.019
regulation of signal transduction GO:0009966 225 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
protein targeting to nucleus GO:0044744 3 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
ameboidal type cell migration GO:0001667 143 0.019
regulation of cell development GO:0060284 100 0.019
cell projection organization GO:0030030 284 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
organic acid metabolic process GO:0006082 31 0.019
regulation of cytoplasmic transport GO:1903649 4 0.018
cellular component disassembly GO:0022411 1 0.018
protein import GO:0017038 3 0.018
stem cell maintenance GO:0019827 4 0.018
protein localization to plasma membrane GO:0072659 1 0.018
carboxylic acid catabolic process GO:0046395 3 0.018
golgi vesicle transport GO:0048193 3 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
mesoderm development GO:0007498 88 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of protein catabolic process GO:0042176 1 0.018
small molecule metabolic process GO:0044281 77 0.018
heterocycle metabolic process GO:0046483 290 0.017
regionalization GO:0003002 274 0.017
gastrulation GO:0007369 208 0.017
transport GO:0006810 220 0.017
organelle localization GO:0051640 49 0.017
protein localization to nucleus GO:0034504 3 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
cartilage development GO:0051216 96 0.017
regulation of binding GO:0051098 3 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
lateral inhibition GO:0046331 1 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
regulation of signaling GO:0023051 235 0.016
cell migration GO:0016477 237 0.016
brain development GO:0007420 293 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
neuron differentiation GO:0030182 353 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
establishment of localization GO:0051234 244 0.016
nuclear migration GO:0007097 3 0.016
actin filament polymerization GO:0030041 2 0.016
pigmentation GO:0043473 85 0.016
cellular protein catabolic process GO:0044257 4 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
regulation of metal ion transport GO:0010959 4 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
nuclear import GO:0051170 3 0.015
regulation of primary metabolic process GO:0080090 311 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular response to organic substance GO:0071310 105 0.015
endosomal transport GO:0016197 2 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
regulation of autophagy GO:0010506 3 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
response to wounding GO:0009611 116 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
biosynthetic process GO:0009058 294 0.015
organelle organization GO:0006996 227 0.015
cell motility GO:0048870 244 0.015
positive regulation of cellular process GO:0048522 201 0.015
axonogenesis GO:0007409 152 0.015
neuron projection development GO:0031175 180 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
cellular localization GO:0051641 97 0.015
regulation of cell shape GO:0008360 1 0.014
positive regulation of secretion GO:0051047 1 0.014
gene expression GO:0010467 252 0.014
single organism nuclear import GO:1902593 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
digestive tract mesoderm development GO:0007502 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
axon extension GO:0048675 45 0.014
regulation of cell communication GO:0010646 232 0.014
wound healing GO:0042060 90 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
outflow tract morphogenesis GO:0003151 1 0.014
regulation of cell morphogenesis GO:0022604 42 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
regulation of neurogenesis GO:0050767 87 0.014
membrane invagination GO:0010324 1 0.014
regulation of cellular component organization GO:0051128 86 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of cell activation GO:0050865 1 0.013
regulation of gene expression GO:0010468 265 0.013
wnt signaling pathway GO:0016055 80 0.013
cell substrate adhesion GO:0031589 4 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
macroautophagy GO:0016236 1 0.013
vasculature development GO:0001944 278 0.013
membrane fusion GO:0061025 2 0.013
negative chemotaxis GO:0050919 1 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
establishment of organelle localization GO:0051656 45 0.013
positive regulation of cell division GO:0051781 2 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
single organism metabolic process GO:0044710 217 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
alcohol biosynthetic process GO:0046165 2 0.013
regulation of dendrite development GO:0050773 3 0.013
primary neural tube formation GO:0014020 1 0.013
striated muscle cell development GO:0055002 108 0.013
fat soluble vitamin metabolic process GO:0006775 4 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
positive regulation of glucose transport GO:0010828 1 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
generation of neurons GO:0048699 385 0.013
regulation of blood vessel size GO:0050880 2 0.013
guanosine containing compound catabolic process GO:1901069 2 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
cell death GO:0008219 121 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
sequestering of metal ion GO:0051238 3 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
single organism organelle organization GO:1902589 199 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
interspecies interaction between organisms GO:0044419 4 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
cell growth GO:0016049 57 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
sensory organ development GO:0007423 393 0.012
regulation of nervous system development GO:0051960 90 0.012
regeneration GO:0031099 91 0.012
chordate embryonic development GO:0043009 271 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
energy reserve metabolic process GO:0006112 2 0.012
rna localization GO:0006403 4 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
cellular ketone metabolic process GO:0042180 11 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
rna metabolic process GO:0016070 219 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
regulation of filopodium assembly GO:0051489 2 0.012
female sex differentiation GO:0046660 4 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
protein import into nucleus GO:0006606 3 0.011
germ line stem cell maintenance GO:0030718 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
regulation of biosynthetic process GO:0009889 250 0.011
organelle assembly GO:0070925 110 0.011
negative regulation of defense response GO:0031348 2 0.011
heart development GO:0007507 313 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
exocytosis GO:0006887 1 0.011
regulation of response to stimulus GO:0048583 269 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
muscle cell development GO:0055001 115 0.011
organic acid catabolic process GO:0016054 3 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
positive regulation of glucose import GO:0046326 1 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
organelle fusion GO:0048284 3 0.011
small molecule catabolic process GO:0044282 3 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
regulation of cell projection organization GO:0031344 44 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010
immune system process GO:0002376 241 0.010
regulation of neuron differentiation GO:0045664 56 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010
intracellular signal transduction GO:0035556 85 0.010
eye morphogenesis GO:0048592 144 0.010
cellular response to growth factor stimulus GO:0071363 39 0.010
death GO:0016265 121 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of cellular biosynthetic process GO:0031326 245 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
positive regulation of developmental process GO:0051094 50 0.010
macromolecule modification GO:0043412 111 0.010
negative regulation of signal transduction GO:0009968 94 0.010
negative regulation of catabolic process GO:0009895 3 0.010
single organism transport GO:0044765 206 0.010

leprel2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
bone disease DOID:0080001 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
disease of metabolism DOID:0014667 0 0.012
nervous system disease DOID:863 0 0.010