Danio rerio

10 known processes

usp25

ubiquitin specific protease 25

(Aliases: zgc:55791,wu:fp97a04,wu:fo67e06,wu:fi33c05)

usp25 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.344
Human
signal transduction GO:0007165 455 0.237
regulation of metabolic process GO:0019222 359 0.204
negative regulation of biological process GO:0048519 304 0.175
protein metabolic process GO:0019538 183 0.165
Human
modification dependent protein catabolic process GO:0019941 3 0.147
response to chemical GO:0042221 320 0.146
regulation of biosynthetic process GO:0009889 250 0.144
cell surface receptor signaling pathway GO:0007166 325 0.135
negative regulation of cellular process GO:0048523 283 0.117
positive regulation of catabolic process GO:0009896 4 0.116
phagocytosis GO:0006909 3 0.115
ubiquitin dependent protein catabolic process GO:0006511 3 0.109
regulation of signaling GO:0023051 235 0.103
single organism metabolic process GO:0044710 217 0.102
regulation of macromolecule metabolic process GO:0060255 317 0.102
biosynthetic process GO:0009058 294 0.095
modification dependent macromolecule catabolic process GO:0043632 3 0.092
positive regulation of cellular catabolic process GO:0031331 3 0.091
larval development GO:0002164 2 0.091
regulation of circadian rhythm GO:0042752 4 0.090
locomotor rhythm GO:0045475 3 0.089
cellular protein catabolic process GO:0044257 4 0.084
regulation of signal transduction GO:0009966 225 0.082
nucleocytoplasmic transport GO:0006913 4 0.081
maintenance of location GO:0051235 4 0.078
positive regulation of transport GO:0051050 2 0.077
establishment of protein localization to organelle GO:0072594 4 0.077
aging GO:0007568 2 0.077
regulation of cellular metabolic process GO:0031323 320 0.076
cellular macromolecule biosynthetic process GO:0034645 224 0.073
regulation of protein import into nucleus GO:0042306 2 0.070
single organism organelle organization GO:1902589 199 0.070
nuclear transport GO:0051169 4 0.068
nitrogen compound metabolic process GO:0006807 319 0.065
regulation of cell communication GO:0010646 232 0.065
protein localization to nucleus GO:0034504 3 0.064
cytokinesis GO:0000910 3 0.064
negative regulation of cell communication GO:0010648 96 0.064
organic cyclic compound metabolic process GO:1901360 301 0.063
phosphorus metabolic process GO:0006793 109 0.061
golgi vesicle transport GO:0048193 3 0.061
protein dephosphorylation GO:0006470 3 0.060
meiotic nuclear division GO:0007126 4 0.059
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.058
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.057
regulation of response to stimulus GO:0048583 269 0.057
meiotic cell cycle process GO:1903046 3 0.057
microtubule organizing center organization GO:0031023 1 0.056
cellular biosynthetic process GO:0044249 286 0.056
regulation of primary metabolic process GO:0080090 311 0.056
cell death GO:0008219 121 0.056
programmed cell death GO:0012501 119 0.054
protein import GO:0017038 3 0.054
single organism nuclear import GO:1902593 3 0.054
cellular protein metabolic process GO:0044267 129 0.054
Human
cellular component biogenesis GO:0044085 178 0.054
regulation of cellular biosynthetic process GO:0031326 245 0.053
positive regulation of biological process GO:0048518 253 0.053
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.051
nucleic acid templated transcription GO:0097659 181 0.050
nucleobase containing compound biosynthetic process GO:0034654 205 0.049
single organism localization GO:1902578 225 0.048
lipid storage GO:0019915 1 0.048
organelle organization GO:0006996 227 0.048
adult behavior GO:0030534 2 0.048
lateral inhibition GO:0046331 1 0.048
negative regulation of cytoplasmic transport GO:1903650 2 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.047
cellular protein modification process GO:0006464 100 0.047
Human
rna metabolic process GO:0016070 219 0.045
neuron development GO:0048666 262 0.045
cellular nitrogen compound biosynthetic process GO:0044271 218 0.045
heterocycle metabolic process GO:0046483 290 0.044
macromolecule biosynthetic process GO:0009059 227 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.042
cell part morphogenesis GO:0032990 246 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
embryonic organ development GO:0048568 381 0.042
stem cell proliferation GO:0072089 4 0.042
regulation of protein targeting GO:1903533 2 0.041
macromolecular complex subunit organization GO:0043933 74 0.041
gtp metabolic process GO:0046039 4 0.041
entrainment of circadian clock GO:0009649 2 0.041
tube morphogenesis GO:0035239 349 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.040
cell projection organization GO:0030030 284 0.040
regulation of carbohydrate metabolic process GO:0006109 4 0.040
multi organism process GO:0051704 134 0.040
protein import into nucleus GO:0006606 3 0.039
protein targeting to nucleus GO:0044744 3 0.039
regulation of rna metabolic process GO:0051252 224 0.039
single organism transport GO:0044765 206 0.039
regulation of multicellular organism growth GO:0040014 4 0.039
cellular response to chemical stimulus GO:0070887 157 0.038
regulation of protein ubiquitination GO:0031396 3 0.038
gtp catabolic process GO:0006184 2 0.038
transport GO:0006810 220 0.038
nucleobase containing compound metabolic process GO:0006139 274 0.038
organic substance biosynthetic process GO:1901576 289 0.038
nucleic acid metabolic process GO:0090304 244 0.038
multicellular organism growth GO:0035264 4 0.037
stem cell maintenance GO:0019827 4 0.037
mitochondrion organization GO:0007005 4 0.037
rna biosynthetic process GO:0032774 181 0.037
macromolecule modification GO:0043412 111 0.037
Human
nuclear import GO:0051170 3 0.037
proteasomal protein catabolic process GO:0010498 2 0.037
positive regulation of cellular process GO:0048522 201 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
regulation of protein transport GO:0051223 3 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
regulation of organelle assembly GO:1902115 4 0.036
erk1 and erk2 cascade GO:0070371 4 0.036
regulation of nucleic acid templated transcription GO:1903506 213 0.036
embryo development ending in birth or egg hatching GO:0009792 271 0.036
amine metabolic process GO:0009308 2 0.036
digestive system development GO:0055123 289 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.036
apoptotic process GO:0006915 116 0.035
negative regulation of ras protein signal transduction GO:0046580 1 0.035
lamellipodium organization GO:0097581 1 0.035
dna templated transcription elongation GO:0006354 3 0.034
negative regulation of signal transduction GO:0009968 94 0.034
meiotic chromosome segregation GO:0045132 3 0.034
cellular carbohydrate metabolic process GO:0044262 4 0.034
phosphate containing compound metabolic process GO:0006796 108 0.034
regulation of nucleocytoplasmic transport GO:0046822 2 0.033
cellular amine metabolic process GO:0044106 2 0.033
negative regulation of response to stimulus GO:0048585 104 0.033
regulation of transcription dna templated GO:0006355 213 0.033
brain development GO:0007420 293 0.032
regulation of protein catabolic process GO:0042176 1 0.032
response to external stimulus GO:0009605 264 0.032
gene expression GO:0010467 252 0.032
regulation of nucleoside metabolic process GO:0009118 2 0.032
regulation of establishment of protein localization GO:0070201 4 0.031
development of primary female sexual characteristics GO:0046545 4 0.031
wnt signaling pathway GO:0016055 80 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
cell projection morphogenesis GO:0048858 244 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
cellular response to organic substance GO:0071310 105 0.030
response to stress GO:0006950 263 0.030
negative regulation of protein kinase activity GO:0006469 4 0.030
lamellipodium assembly GO:0030032 1 0.030
neuron differentiation GO:0030182 353 0.030
carbohydrate biosynthetic process GO:0016051 1 0.030
transcription dna templated GO:0006351 181 0.030
response to organic substance GO:0010033 153 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
regulation of protein polymerization GO:0032271 2 0.030
response to topologically incorrect protein GO:0035966 2 0.029
enzyme linked receptor protein signaling pathway GO:0007167 106 0.029
centrosome organization GO:0051297 1 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
regulation of nucleotide catabolic process GO:0030811 2 0.028
regulation of gene expression GO:0010468 265 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
single organism membrane fusion GO:0044801 2 0.028
cellular component movement GO:0006928 335 0.027
locomotion GO:0040011 313 0.027
negative regulation of programmed cell death GO:0043069 58 0.027
organelle assembly GO:0070925 110 0.027
head development GO:0060322 303 0.027
cell migration GO:0016477 237 0.027
positive regulation of cellular metabolic process GO:0031325 94 0.027
regulation of protein complex assembly GO:0043254 3 0.026
response to alkaloid GO:0043279 2 0.026
response to vitamin GO:0033273 3 0.026
central nervous system development GO:0007417 387 0.026
negative regulation of tor signaling GO:0032007 2 0.026
cellular component disassembly GO:0022411 1 0.026
blood vessel morphogenesis GO:0048514 216 0.026
peptidyl lysine acetylation GO:0018394 2 0.026
regulation of neural precursor cell proliferation GO:2000177 3 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
actin filament polymerization GO:0030041 2 0.025
regulation of apoptotic process GO:0042981 98 0.025
regulation of cell death GO:0010941 103 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
regulation of stem cell proliferation GO:0072091 2 0.025
digestive tract morphogenesis GO:0048546 231 0.025
negative regulation of kinase activity GO:0033673 4 0.025
negative regulation of mapk cascade GO:0043409 4 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
establishment of localization GO:0051234 244 0.025
protein polyubiquitination GO:0000209 4 0.025
negative regulation of cellular metabolic process GO:0031324 77 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
system process GO:0003008 185 0.024
cellular component assembly GO:0022607 170 0.024
meiosis i GO:0007127 1 0.024
positive regulation of cell cycle GO:0045787 3 0.024
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.024
developmental programmed cell death GO:0010623 4 0.024
establishment of synaptic vesicle localization GO:0097480 1 0.024
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.024
immune system process GO:0002376 241 0.024
cell cycle process GO:0022402 53 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.023
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.023
apoptotic process involved in development GO:1902742 2 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
protein polymerization GO:0051258 4 0.023
energy reserve metabolic process GO:0006112 2 0.023
neurotransmitter transport GO:0006836 2 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
regulation of protein complex disassembly GO:0043244 1 0.023
spindle assembly GO:0051225 2 0.023
protein complex disassembly GO:0043241 1 0.023
macromolecular complex disassembly GO:0032984 1 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
negative regulation of protein complex assembly GO:0031333 1 0.022
regulation of binding GO:0051098 3 0.022
negative regulation of signaling GO:0023057 96 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
vasculature development GO:0001944 278 0.022
regulation of developmental process GO:0050793 247 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
hormone transport GO:0009914 2 0.022
mitotic dna integrity checkpoint GO:0044774 4 0.022
camera type eye development GO:0043010 222 0.022
cognition GO:0050890 1 0.022
protein modification process GO:0036211 100 0.022
Human
locomotory behavior GO:0007626 34 0.022
positive regulation of map kinase activity GO:0043406 3 0.022
post embryonic organ development GO:0048569 4 0.022
response to unfolded protein GO:0006986 2 0.022
anterior posterior pattern specification GO:0009952 152 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
mitotic cell cycle process GO:1903047 48 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
positive regulation of stress activated mapk cascade GO:0032874 3 0.021
positive regulation of gtpase activity GO:0043547 1 0.021
axon development GO:0061564 166 0.021
er to golgi vesicle mediated transport GO:0006888 1 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
positive regulation of notch signaling pathway GO:0045747 3 0.021
vacuolar transport GO:0007034 2 0.021
positive regulation of metabolic process GO:0009893 108 0.021
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
sensory organ morphogenesis GO:0090596 200 0.021
cellular response to external stimulus GO:0071496 2 0.021
response to light stimulus GO:0009416 46 0.021
response to drug GO:0042493 3 0.021
neuroblast proliferation GO:0007405 2 0.021
generation of neurons GO:0048699 385 0.021
oxoacid metabolic process GO:0043436 31 0.020
regulation of autophagy GO:0010506 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
peptide transport GO:0015833 1 0.020
sex determination GO:0007530 1 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
protein demethylation GO:0006482 2 0.020
chromosome organization GO:0051276 31 0.020
organic substance transport GO:0071702 58 0.020
specification of symmetry GO:0009799 204 0.020
ameboidal type cell migration GO:0001667 143 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
negative regulation of map kinase activity GO:0043407 2 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
chordate embryonic development GO:0043009 271 0.019
gastrulation GO:0007369 208 0.019
autophagy GO:0006914 4 0.019
death GO:0016265 121 0.019
axonogenesis GO:0007409 152 0.019
eye development GO:0001654 277 0.019
cellular component morphogenesis GO:0032989 336 0.019
cell motility GO:0048870 244 0.019
growth GO:0040007 174 0.019
regulation of biological quality GO:0065008 263 0.019
synaptic vesicle transport GO:0048489 1 0.019
regionalization GO:0003002 274 0.019
protein complex localization GO:0031503 1 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
establishment of localization in cell GO:0051649 77 0.019
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
regulation of filopodium assembly GO:0051489 2 0.019
synaptic vesicle endocytosis GO:0048488 1 0.019
membrane invagination GO:0010324 1 0.019
intracellular signal transduction GO:0035556 85 0.018
female sex differentiation GO:0046660 4 0.018
digestive tract development GO:0048565 265 0.018
hormone secretion GO:0046879 2 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
protein acylation GO:0043543 3 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
negative regulation of intracellular transport GO:0032387 3 0.018
protein acetylation GO:0006473 2 0.018
negative regulation of metabolic process GO:0009892 86 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.018
membrane fusion GO:0061025 2 0.018
sleep GO:0030431 1 0.018
circadian rhythm GO:0007623 19 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
cell morphogenesis GO:0000902 289 0.018
regulation of synapse organization GO:0050807 3 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of cell shape GO:0008360 1 0.018
synaptic vesicle recycling GO:0036465 1 0.018
neurotransmitter secretion GO:0007269 2 0.018
cellular response to nutrient levels GO:0031669 2 0.017
neuron projection development GO:0031175 180 0.017
response to nutrient GO:0007584 3 0.017
primary neural tube formation GO:0014020 1 0.017
female gonad development GO:0008585 4 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
positive regulation of cell division GO:0051781 2 0.017
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
glucose homeostasis GO:0042593 1 0.017
negative regulation of protein transport GO:0051224 3 0.017
activation of mapk activity GO:0000187 3 0.017
intracellular transport GO:0046907 32 0.017
protein secretion GO:0009306 1 0.017
regulation of reproductive process GO:2000241 4 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
regulation of dna replication GO:0006275 3 0.017
homeostatic process GO:0042592 142 0.016
negative regulation of defense response GO:0031348 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
blood vessel development GO:0001568 246 0.016
regulation of protein depolymerization GO:1901879 1 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
localization of cell GO:0051674 244 0.016
response to uv GO:0009411 3 0.016
regulation of tube size GO:0035150 2 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
insulin like growth factor receptor signaling pathway GO:0048009 4 0.016
somatic muscle development GO:0007525 4 0.016
endosomal transport GO:0016197 2 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
organelle fusion GO:0048284 3 0.016
neuron projection morphogenesis GO:0048812 161 0.016
phagocytosis engulfment GO:0006911 1 0.016
regulation of localization GO:0032879 104 0.016
synaptic vesicle localization GO:0097479 1 0.016
cellular response to topologically incorrect protein GO:0035967 2 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
cell cycle GO:0007049 93 0.015
spermatid development GO:0007286 2 0.015
er nucleus signaling pathway GO:0006984 2 0.015
regulation of cytokine production GO:0001817 3 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
behavior GO:0007610 74 0.015
regulation of jun kinase activity GO:0043506 3 0.015
endosome organization GO:0007032 2 0.015
carbohydrate homeostasis GO:0033500 1 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
macroautophagy GO:0016236 1 0.015
post golgi vesicle mediated transport GO:0006892 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
mitotic cell cycle GO:0000278 64 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
mitotic nuclear division GO:0007067 18 0.015
regulation of blood vessel size GO:0050880 2 0.014
cellular response to stress GO:0033554 62 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
camera type eye morphogenesis GO:0048593 108 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of protein metabolic process GO:0051246 56 0.014
histone modification GO:0016570 20 0.014
regulation of wound healing GO:0061041 2 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
angiogenesis GO:0001525 158 0.014
nuclear export GO:0051168 1 0.014
response to glucose GO:0009749 3 0.014
centrosome cycle GO:0007098 1 0.014
regulation of cell development GO:0060284 100 0.014
regulation of molecular function GO:0065009 70 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
protein homooligomerization GO:0051260 3 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of cell projection assembly GO:0060491 4 0.014
regulation of cellular component size GO:0032535 30 0.014
negative regulation of gene expression GO:0010629 65 0.014
positive regulation of cell communication GO:0010647 56 0.014
endoplasmic reticulum unfolded protein response GO:0030968 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
tube closure GO:0060606 1 0.013
negative regulation of intracellular signal transduction GO:1902532 22 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
chromatin organization GO:0006325 22 0.013
response to hydrogen peroxide GO:0042542 3 0.013
cellular response to unfolded protein GO:0034620 2 0.013
regulation of protein binding GO:0043393 3 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
cellular localization GO:0051641 97 0.013
covalent chromatin modification GO:0016569 20 0.013
female meiotic division GO:0007143 2 0.013
response to endogenous stimulus GO:0009719 83 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
dicarboxylic acid transport GO:0006835 1 0.013
stem cell division GO:0017145 1 0.013
regulation of carbohydrate biosynthetic process GO:0043255 1 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
germ line stem cell maintenance GO:0030718 2 0.013
regulation of organ growth GO:0046620 3 0.013
cell aging GO:0007569 2 0.013
cartilage development GO:0051216 96 0.013
regulation of cell activation GO:0050865 1 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
glial cell proliferation GO:0014009 4 0.013
regulation of programmed cell death GO:0043067 101 0.013
cell substrate adhesion GO:0031589 4 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
pyruvate metabolic process GO:0006090 1 0.013
exocytosis GO:0006887 1 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
negative regulation of cytokine production GO:0001818 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
regulation of synapse assembly GO:0051963 3 0.013
skeletal system morphogenesis GO:0048705 102 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.012
regulation of catalytic activity GO:0050790 55 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
regulation of ph GO:0006885 3 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
sensory organ development GO:0007423 393 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
androgen metabolic process GO:0008209 2 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
nuclear division GO:0000280 23 0.012
sexual reproduction GO:0019953 36 0.012
protein depolymerization GO:0051261 1 0.012
lipid homeostasis GO:0055088 3 0.012
sequestering of metal ion GO:0051238 3 0.012
cellular protein complex disassembly GO:0043624 1 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
centrosome duplication GO:0051298 1 0.012
heart looping GO:0001947 94 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
alcohol biosynthetic process GO:0046165 2 0.012
protein complex biogenesis GO:0070271 30 0.012
cellular response to radiation GO:0071478 4 0.012
regulation of cellular component organization GO:0051128 86 0.012
heart development GO:0007507 313 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
regulation of dna recombination GO:0000018 2 0.012
regulation of cellular response to growth factor stimulus GO:0090287 35 0.012
organic substance catabolic process GO:1901575 28 0.012
cartilage condensation GO:0001502 3 0.012
golgi organization GO:0007030 1 0.012
single organism biosynthetic process GO:0044711 71 0.012
response to wounding GO:0009611 116 0.012
cellular protein localization GO:0034613 20 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
mitotic g2 m transition checkpoint GO:0044818 3 0.012
endocrine hormone secretion GO:0060986 2 0.011
smoothened signaling pathway GO:0007224 30 0.011
atp catabolic process GO:0006200 4 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011

usp25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.013