Danio rerio

0 known processes

polm

polymerase (DNA directed), mu

(Aliases: zgc:56122,polmu,MGC56122)

polm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
specification of symmetry GO:0009799 204 0.230
positive regulation of biological process GO:0048518 253 0.180
regulation of immune system process GO:0002682 34 0.178
embryonic heart tube development GO:0035050 133 0.178
gene expression GO:0010467 252 0.175
defense response GO:0006952 47 0.168
signal transduction GO:0007165 455 0.145
single organism transport GO:0044765 206 0.143
aromatic compound biosynthetic process GO:0019438 217 0.141
mitotic nuclear division GO:0007067 18 0.136
regulation of metabolic process GO:0019222 359 0.135
heart development GO:0007507 313 0.132
organelle organization GO:0006996 227 0.132
aging GO:0007568 2 0.126
heterocycle biosynthetic process GO:0018130 215 0.118
positive regulation of cell cycle GO:0045787 3 0.111
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.108
regulation of primary metabolic process GO:0080090 311 0.105
regulation of cellular metabolic process GO:0031323 320 0.103
cellular aromatic compound metabolic process GO:0006725 295 0.098
positive regulation of cellular process GO:0048522 201 0.098
cell projection organization GO:0030030 284 0.097
nucleoside phosphate metabolic process GO:0006753 28 0.096
heart looping GO:0001947 94 0.095
organonitrogen compound metabolic process GO:1901564 74 0.091
determination of left right symmetry GO:0007368 179 0.085
regulation of nitrogen compound metabolic process GO:0051171 251 0.082
embryonic heart tube morphogenesis GO:0003143 108 0.082
regulation of multicellular organismal process GO:0051239 277 0.076
response to biotic stimulus GO:0009607 97 0.073
cellular ketone metabolic process GO:0042180 11 0.069
cell cycle g2 m phase transition GO:0044839 4 0.068
organic cyclic compound biosynthetic process GO:1901362 223 0.067
positive regulation of metabolic process GO:0009893 108 0.067
blood circulation GO:0008015 87 0.064
larval development GO:0002164 2 0.064
regulation of signal transduction GO:0009966 225 0.063
positive regulation of macromolecule metabolic process GO:0010604 93 0.062
regulation of multicellular organism growth GO:0040014 4 0.062
eye development GO:0001654 277 0.062
cellular component assembly GO:0022607 170 0.060
ribose phosphate metabolic process GO:0019693 27 0.059
regulation of cell activation GO:0050865 1 0.059
rna metabolic process GO:0016070 219 0.059
cellular protein metabolic process GO:0044267 129 0.056
positive regulation of cellular metabolic process GO:0031325 94 0.056
determination of heart left right asymmetry GO:0061371 117 0.055
positive regulation of protein kinase b signaling GO:0051897 1 0.055
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.054
spindle assembly GO:0051225 2 0.053
cell projection morphogenesis GO:0048858 244 0.053
response to stress GO:0006950 263 0.051
amine metabolic process GO:0009308 2 0.050
nitrogen compound metabolic process GO:0006807 319 0.050
protein metabolic process GO:0019538 183 0.050
organelle assembly GO:0070925 110 0.050
cellular macromolecule metabolic process GO:0044260 391 0.049
regulation of cellular amine metabolic process GO:0033238 0 0.048
immune system development GO:0002520 191 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.047
regulation of macromolecule metabolic process GO:0060255 317 0.047
transcription dna templated GO:0006351 181 0.047
ion transport GO:0006811 114 0.046
meiotic nuclear division GO:0007126 4 0.045
determination of bilateral symmetry GO:0009855 204 0.044
regulation of cytokine production GO:0001817 3 0.043
biosynthetic process GO:0009058 294 0.043
neuron development GO:0048666 262 0.042
embryonic organ development GO:0048568 381 0.042
oocyte maturation GO:0001556 4 0.042
cell morphogenesis involved in differentiation GO:0000904 195 0.041
mitotic cell cycle GO:0000278 64 0.041
immune system process GO:0002376 241 0.041
hepaticobiliary system development GO:0061008 98 0.040
tube morphogenesis GO:0035239 349 0.040
regulation of response to nutrient levels GO:0032107 1 0.039
regulation of signaling GO:0023051 235 0.039
positive regulation of transport GO:0051050 2 0.039
embryonic organ morphogenesis GO:0048562 274 0.039
positive regulation of map kinase activity GO:0043406 3 0.038
macromolecule modification GO:0043412 111 0.038
positive regulation of gene expression GO:0010628 71 0.037
anterior posterior pattern specification GO:0009952 152 0.037
cellular amine metabolic process GO:0044106 2 0.037
regulation of developmental process GO:0050793 247 0.036
positive regulation of cell death GO:0010942 29 0.036
meiotic cell cycle process GO:1903046 3 0.036
multicellular organism growth GO:0035264 4 0.035
rna localization GO:0006403 4 0.035
regulation of response to stimulus GO:0048583 269 0.034
protein modification process GO:0036211 100 0.033
cellular protein modification process GO:0006464 100 0.033
heterocycle metabolic process GO:0046483 290 0.033
cytoskeleton organization GO:0007010 96 0.032
regionalization GO:0003002 274 0.032
regulation of protein metabolic process GO:0051246 56 0.032
regulation of gene expression GO:0010468 265 0.032
regulation of cell differentiation GO:0045595 142 0.032
male meiosis GO:0007140 2 0.032
intracellular signal transduction GO:0035556 85 0.031
carboxylic acid metabolic process GO:0019752 22 0.031
nucleic acid metabolic process GO:0090304 244 0.030
regulation of metal ion transport GO:0010959 4 0.030
establishment of localization GO:0051234 244 0.030
nuclear division GO:0000280 23 0.030
regulation of response to cytokine stimulus GO:0060759 3 0.029
small molecule metabolic process GO:0044281 77 0.029
purine nucleotide metabolic process GO:0006163 27 0.029
mitotic cell cycle process GO:1903047 48 0.029
purine containing compound metabolic process GO:0072521 29 0.029
multi organism process GO:0051704 134 0.029
maintenance of location GO:0051235 4 0.028
ribonucleotide metabolic process GO:0009259 27 0.028
spermatid development GO:0007286 2 0.028
cellular protein catabolic process GO:0044257 4 0.028
phosphorylation GO:0016310 69 0.028
cell morphogenesis GO:0000902 289 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
phagocytosis GO:0006909 3 0.027
negative regulation of mitosis GO:0045839 3 0.027
heart morphogenesis GO:0003007 156 0.027
cell part morphogenesis GO:0032990 246 0.026
regulation of reproductive process GO:2000241 4 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
circulatory system process GO:0003013 87 0.025
secondary metabolic process GO:0019748 3 0.024
purine ribonucleotide metabolic process GO:0009150 27 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.024
regulation of macromolecule biosynthetic process GO:0010556 225 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
neuroblast differentiation GO:0014016 1 0.023
regulation of cytokine mediated signaling pathway GO:0001959 3 0.023
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.023
microtubule organizing center organization GO:0031023 1 0.023
regulation of molecular function GO:0065009 70 0.023
sensory perception of chemical stimulus GO:0007606 3 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
microtubule based process GO:0007017 60 0.022
cellular component morphogenesis GO:0032989 336 0.022
lipid storage GO:0019915 1 0.022
single organism organelle organization GO:1902589 199 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
chromosome organization GO:0051276 31 0.022
cyclic nucleotide biosynthetic process GO:0009190 18 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
regulation of response to stress GO:0080134 36 0.021
growth GO:0040007 174 0.021
sensory organ development GO:0007423 393 0.021
positive regulation of cell activation GO:0050867 1 0.021
action potential GO:0001508 19 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
response to ionizing radiation GO:0010212 6 0.021
negative regulation of catabolic process GO:0009895 3 0.021
camera type eye development GO:0043010 222 0.021
chromatin organization GO:0006325 22 0.021
regulation of leukocyte differentiation GO:1902105 5 0.021
rna biosynthetic process GO:0032774 181 0.020
apoptotic process involved in development GO:1902742 2 0.020
neuroblast fate commitment GO:0014017 1 0.020
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
stem cell division GO:0017145 1 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
spermatid differentiation GO:0048515 2 0.020
carbohydrate biosynthetic process GO:0016051 1 0.020
organelle fission GO:0048285 23 0.019
response to other organism GO:0051707 97 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of cellular component organization GO:0051128 86 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
neuron differentiation GO:0030182 353 0.019
retina development in camera type eye GO:0060041 146 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
centrosome organization GO:0051297 1 0.019
pole plasm assembly GO:0007315 4 0.019
negative regulation of signal transduction GO:0009968 94 0.018
reciprocal meiotic recombination GO:0007131 1 0.018
modulation by virus of host morphology or physiology GO:0019048 1 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
regulation of tube size GO:0035150 2 0.018
negative regulation of signaling GO:0023057 96 0.017
regulation of biosynthetic process GO:0009889 250 0.017
positive regulation of secretion GO:0051047 1 0.017
defense response to fungus GO:0050832 2 0.017
positive regulation of cytokine production GO:0001819 2 0.017
homeostatic process GO:0042592 142 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
negative regulation of metabolic process GO:0009892 86 0.017
negative regulation of nuclear division GO:0051784 3 0.017
organic substance biosynthetic process GO:1901576 289 0.017
oxoacid metabolic process GO:0043436 31 0.017
methylation GO:0032259 22 0.017
lymphocyte homeostasis GO:0002260 1 0.017
endocrine system development GO:0035270 65 0.017
response to nutrient GO:0007584 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
macromolecule methylation GO:0043414 19 0.016
liver development GO:0001889 96 0.016
cellular response to nutrient levels GO:0031669 2 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
heart contraction GO:0060047 71 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
single organism metabolic process GO:0044710 217 0.016
regulation of transcription dna templated GO:0006355 213 0.016
intracellular mrna localization GO:0008298 1 0.016
neurological system process GO:0050877 62 0.016
regulation of organelle organization GO:0033043 29 0.016
cell fate determination GO:0001709 7 0.016
leukocyte homeostasis GO:0001776 2 0.016
macromolecular complex assembly GO:0065003 35 0.016
protein secretion GO:0009306 1 0.016
dna catabolic process GO:0006308 1 0.016
thymus development GO:0048538 10 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
mitochondrion organization GO:0007005 4 0.015
negative regulation of protein complex assembly GO:0031333 1 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
immune response GO:0006955 28 0.015
regulation of localization GO:0032879 104 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
leukocyte differentiation GO:0002521 25 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
epiboly GO:0090504 41 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
digestive tract morphogenesis GO:0048546 231 0.015
protein localization GO:0008104 40 0.015
regulation of autophagy GO:0010506 3 0.014
b cell activation GO:0042113 2 0.014
phosphorus metabolic process GO:0006793 109 0.014
macroautophagy GO:0016236 1 0.014
epithelial cell differentiation GO:0030855 116 0.014
striated muscle tissue development GO:0014706 110 0.014
neuroblast proliferation GO:0007405 2 0.014
developmental programmed cell death GO:0010623 4 0.014
cellular component movement GO:0006928 335 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.014
dna metabolic process GO:0006259 27 0.014
negative regulation of cell communication GO:0010648 96 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
protein phosphorylation GO:0006468 47 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
regulation of endopeptidase activity GO:0052548 23 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
activation of mapk activity GO:0000187 3 0.013
nucleotide metabolic process GO:0009117 28 0.013
nucleus organization GO:0006997 7 0.013
regulation of blood vessel size GO:0050880 2 0.013
somatic muscle development GO:0007525 4 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
apoptotic process involved in morphogenesis GO:0060561 2 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
regulation of calcium ion transport GO:0051924 2 0.013
regulation of protein modification process GO:0031399 29 0.012
erythrocyte maturation GO:0043249 8 0.012
glucose homeostasis GO:0042593 1 0.012
negative regulation of cellular component organization GO:0051129 16 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
regulation of myotube differentiation GO:0010830 2 0.012
muscle organ development GO:0007517 101 0.012
sister chromatid cohesion GO:0007062 2 0.012
multicellular organismal signaling GO:0035637 22 0.012
regulation of proteolysis GO:0030162 24 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
embryonic hemopoiesis GO:0035162 53 0.012
anatomical structure homeostasis GO:0060249 36 0.012
muscle structure development GO:0061061 196 0.012
asymmetric protein localization GO:0008105 6 0.012
peptide transport GO:0015833 1 0.012
gtp metabolic process GO:0046039 4 0.012
head development GO:0060322 303 0.012
negative regulation of dna replication GO:0008156 2 0.012
positive regulation of developmental process GO:0051094 50 0.011
response to uv GO:0009411 3 0.011
dna biosynthetic process GO:0071897 3 0.011
neuron projection development GO:0031175 180 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
system process GO:0003008 185 0.011
cell aging GO:0007569 2 0.011
cellular response to stress GO:0033554 62 0.011
locomotion GO:0040011 313 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
response to abiotic stimulus GO:0009628 122 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
astrocyte differentiation GO:0048708 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of inflammatory response GO:0050727 2 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
female sex differentiation GO:0046660 4 0.011
germ cell development GO:0007281 22 0.011
meiosis i GO:0007127 1 0.011
regulation of cell cycle GO:0051726 52 0.011
meiosis ii GO:0007135 1 0.011
response to drug GO:0042493 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
g protein coupled receptor signaling pathway GO:0007186 74 0.011
cellular component biogenesis GO:0044085 178 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
interaction with host GO:0051701 4 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.010
gastrulation GO:0007369 208 0.010
cell death GO:0008219 121 0.010
regulation of cell communication GO:0010646 232 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010

polm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
reproductive system disease DOID:15 0 0.044
bone disease DOID:0080001 0 0.023
musculoskeletal system disease DOID:17 0 0.023
connective tissue disease DOID:65 0 0.023
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
nervous system disease DOID:863 0 0.017
eye disease DOID:5614 0 0.017