Danio rerio

0 known processes

icn

ictacalcin

(Aliases: mg:cb02f02,s100a4a,MGC123122,wu:fa91d07,fa91d07)

icn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to abiotic stimulus GO:0009628 122 0.451
positive regulation of biological process GO:0048518 253 0.345
neurological system process GO:0050877 62 0.290
single organism localization GO:1902578 225 0.258
regulation of biological quality GO:0065008 263 0.244
system process GO:0003008 185 0.214
actomyosin structure organization GO:0031032 53 0.211
negative regulation of biological process GO:0048519 304 0.203
membrane raft organization GO:0031579 1 0.191
plasma membrane repair GO:0001778 2 0.189
regulation of gtp catabolic process GO:0033124 2 0.169
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.160
positive regulation of cell matrix adhesion GO:0001954 1 0.157
regulation of binding GO:0051098 3 0.156
establishment of localization GO:0051234 244 0.142
transport GO:0006810 220 0.138
signal transduction GO:0007165 455 0.132
regulation of metabolic process GO:0019222 359 0.130
blood vessel development GO:0001568 246 0.129
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.128
purine nucleotide metabolic process GO:0006163 27 0.126
establishment of protein localization to plasma membrane GO:0090002 1 0.123
cellular component assembly GO:0022607 170 0.122
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.118
small molecule metabolic process GO:0044281 77 0.115
positive regulation of nucleoside metabolic process GO:0045979 1 0.112
gtp catabolic process GO:0006184 2 0.109
i kappab kinase nf kappab signaling GO:0007249 4 0.106
positive regulation of cellular component biogenesis GO:0044089 3 0.106
guanosine containing compound catabolic process GO:1901069 2 0.102
regulation of primary metabolic process GO:0080090 311 0.101
regulation of gtpase activity GO:0043087 2 0.099
apoptotic process GO:0006915 116 0.098
regulation of nucleoside metabolic process GO:0009118 2 0.096
response to radiation GO:0009314 51 0.095
guanosine containing compound metabolic process GO:1901068 4 0.094
lipid digestion GO:0044241 3 0.092
positive regulation of gtp catabolic process GO:0033126 1 0.092
regulation of signaling GO:0023051 235 0.092
response to lipid GO:0033993 60 0.091
organic cyclic compound metabolic process GO:1901360 301 0.090
organelle fusion GO:0048284 3 0.089
carbohydrate derivative metabolic process GO:1901135 61 0.088
regulation of establishment of protein localization GO:0070201 4 0.087
intracellular signal transduction GO:0035556 85 0.082
cellular aromatic compound metabolic process GO:0006725 295 0.082
regulation of signal transduction GO:0009966 225 0.081
positive regulation of catabolic process GO:0009896 4 0.080
regulation of cell death GO:0010941 103 0.080
negative regulation of cellular process GO:0048523 283 0.078
response to acid chemical GO:0001101 17 0.077
protein secretion GO:0009306 1 0.077
regulation of nucleotide catabolic process GO:0030811 2 0.076
cell motility GO:0048870 244 0.076
reactive oxygen species biosynthetic process GO:1903409 1 0.074
positive regulation of blood circulation GO:1903524 2 0.074
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.074
vesicle organization GO:0016050 6 0.073
heart development GO:0007507 313 0.072
small gtpase mediated signal transduction GO:0007264 8 0.070
regulation of nitrogen compound metabolic process GO:0051171 251 0.068
gtp metabolic process GO:0046039 4 0.067
regulation of cellular metabolic process GO:0031323 320 0.066
regulation of rho protein signal transduction GO:0035023 2 0.066
long chain fatty acid transport GO:0015909 1 0.066
single organism organelle organization GO:1902589 199 0.065
regulation of blood vessel size GO:0050880 2 0.065
regulation of cellular component organization GO:0051128 86 0.064
rho protein signal transduction GO:0007266 5 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.062
positive regulation of gtpase activity GO:0043547 1 0.062
stem cell proliferation GO:0072089 4 0.061
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.060
vasculature development GO:0001944 278 0.059
nitrogen compound metabolic process GO:0006807 319 0.059
organelle organization GO:0006996 227 0.059
g1 s transition of mitotic cell cycle GO:0000082 1 0.057
positive regulation of nucleotide catabolic process GO:0030813 1 0.057
regulation of defense response to virus by host GO:0050691 1 0.056
ameboidal type cell migration GO:0001667 143 0.054
actin cytoskeleton organization GO:0030036 63 0.053
fatty acid transport GO:0015908 1 0.053
cellular component morphogenesis GO:0032989 336 0.053
muscle structure development GO:0061061 196 0.052
positive regulation of cellular catabolic process GO:0031331 3 0.051
adherens junction organization GO:0034332 4 0.051
response to light stimulus GO:0009416 46 0.050
detection of visible light GO:0009584 12 0.050
cell morphogenesis GO:0000902 289 0.050
protein localization to plasma membrane GO:0072659 1 0.050
positive regulation of cell cycle GO:0045787 3 0.050
protein localization GO:0008104 40 0.050
single organism transport GO:0044765 206 0.050
positive regulation of transport GO:0051050 2 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.049
nitric oxide metabolic process GO:0046209 2 0.049
positive regulation of cytokine production GO:0001819 2 0.049
meiotic nuclear division GO:0007126 4 0.048
cellular response to acid chemical GO:0071229 8 0.048
cellular carbohydrate metabolic process GO:0044262 4 0.047
regulation of cytoplasmic transport GO:1903649 4 0.047
adherens junction assembly GO:0034333 1 0.046
homeostatic process GO:0042592 142 0.046
organic substance transport GO:0071702 58 0.045
cellular component biogenesis GO:0044085 178 0.045
epithelial cell differentiation GO:0030855 116 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
regulation of biosynthetic process GO:0009889 250 0.044
establishment of localization in cell GO:0051649 77 0.044
cytokinesis GO:0000910 3 0.044
developmental growth GO:0048589 166 0.042
protein import GO:0017038 3 0.042
regulation of cell communication GO:0010646 232 0.041
blood vessel morphogenesis GO:0048514 216 0.041
epidermis development GO:0008544 48 0.041
single organism membrane organization GO:0044802 20 0.040
regulation of locomotion GO:0040012 55 0.040
regulation of protein transport GO:0051223 3 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
regulation of hydrolase activity GO:0051336 28 0.039
gliogenesis GO:0042063 45 0.039
nitric oxide biosynthetic process GO:0006809 2 0.039
immune system development GO:0002520 191 0.039
cellular component movement GO:0006928 335 0.038
death GO:0016265 121 0.038
cell substrate junction assembly GO:0007044 2 0.038
regulation of cell substrate adhesion GO:0010810 1 0.038
positive regulation of cell substrate adhesion GO:0010811 1 0.037
astrocyte differentiation GO:0048708 1 0.037
protein heterooligomerization GO:0051291 1 0.036
circulatory system process GO:0003013 87 0.036
regulation of organelle organization GO:0033043 29 0.036
positive regulation of defense response to virus by host GO:0002230 0 0.036
striated muscle tissue development GO:0014706 110 0.036
immune system process GO:0002376 241 0.036
axon ensheathment in central nervous system GO:0032291 2 0.036
central nervous system development GO:0007417 387 0.035
tissue remodeling GO:0048771 4 0.035
localization of cell GO:0051674 244 0.035
positive regulation of cytoskeleton organization GO:0051495 3 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.035
response to organic cyclic compound GO:0014070 51 0.035
regulation of intracellular signal transduction GO:1902531 57 0.035
tissue regeneration GO:0042246 74 0.035
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.034
embryonic skeletal joint development GO:0072498 3 0.034
zymogen activation GO:0031638 3 0.034
regulation of tube size GO:0035150 2 0.034
actin filament based process GO:0030029 64 0.034
heterocycle metabolic process GO:0046483 290 0.034
hemopoiesis GO:0030097 183 0.033
response to drug GO:0042493 3 0.033
nucleobase containing small molecule metabolic process GO:0055086 32 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
hematopoietic or lymphoid organ development GO:0048534 191 0.033
regulation of cell development GO:0060284 100 0.032
regulation of rac protein signal transduction GO:0035020 1 0.032
reactive nitrogen species metabolic process GO:2001057 0 0.032
behavior GO:0007610 74 0.032
response to chemical GO:0042221 320 0.032
single organism membrane fusion GO:0044801 2 0.032
positive regulation of cell death GO:0010942 29 0.032
phosphate containing compound metabolic process GO:0006796 108 0.031
amide transport GO:0042886 12 0.031
xenobiotic metabolic process GO:0006805 4 0.031
regulation of nucleotide metabolic process GO:0006140 17 0.030
type i interferon production GO:0032606 2 0.030
regulation of cellular component movement GO:0051270 55 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
energy reserve metabolic process GO:0006112 2 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.030
regulation of purine nucleotide metabolic process GO:1900542 17 0.029
muscle cell development GO:0055001 115 0.029
positive regulation of cell adhesion GO:0045785 1 0.029
regulation of purine nucleotide catabolic process GO:0033121 2 0.029
striated muscle cell differentiation GO:0051146 129 0.028
stress fiber assembly GO:0043149 5 0.028
single organism metabolic process GO:0044710 217 0.028
glial cell proliferation GO:0014009 4 0.028
myeloid cell homeostasis GO:0002262 56 0.028
collagen metabolic process GO:0032963 2 0.028
regulation of circadian rhythm GO:0042752 4 0.027
cognition GO:0050890 1 0.027
regulation of rho gtpase activity GO:0032319 1 0.027
positive regulation of cellular process GO:0048522 201 0.027
purine containing compound metabolic process GO:0072521 29 0.027
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
angiogenesis GO:0001525 158 0.026
ras protein signal transduction GO:0007265 7 0.026
nucleoside phosphate metabolic process GO:0006753 28 0.026
actin filament organization GO:0007015 15 0.026
regulation of actin filament based process GO:0032970 9 0.026
regulation of striated muscle contraction GO:0006942 2 0.026
protein import into nucleus GO:0006606 3 0.026
aging GO:0007568 2 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
regulation of localization GO:0032879 104 0.025
transcription dna templated GO:0006351 181 0.025
heart contraction GO:0060047 71 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
phagocytosis GO:0006909 3 0.024
cell substrate adhesion GO:0031589 4 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
cellular component disassembly GO:0022411 1 0.024
regulation of programmed cell death GO:0043067 101 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
cell substrate adherens junction assembly GO:0007045 1 0.024
aromatic compound catabolic process GO:0019439 15 0.023
embryonic heart tube morphogenesis GO:0003143 108 0.023
protein localization to nucleus GO:0034504 3 0.023
intestinal cholesterol absorption GO:0030299 2 0.023
transmembrane transport GO:0055085 120 0.023
regulation of cell matrix adhesion GO:0001952 1 0.023
stem cell maintenance GO:0019827 4 0.023
transmission of nerve impulse GO:0019226 19 0.023
cellular localization GO:0051641 97 0.023
positive regulation of cell activation GO:0050867 1 0.023
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.022
response to steroid hormone GO:0048545 35 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
regulation of response to stimulus GO:0048583 269 0.022
positive regulation of hydrolase activity GO:0051345 13 0.022
ribose phosphate metabolic process GO:0019693 27 0.022
regulation of molecular function GO:0065009 70 0.022
cellular ion homeostasis GO:0006873 17 0.022
response to decreased oxygen levels GO:0036293 25 0.021
dorsal ventral pattern formation GO:0009953 125 0.021
polyol transport GO:0015791 7 0.021
sensory perception of light stimulus GO:0050953 19 0.021
response to corticosteroid GO:0031960 1 0.021
detection of external stimulus GO:0009581 24 0.021
regulation of phosphate metabolic process GO:0019220 43 0.020
protein complex subunit organization GO:0071822 46 0.020
leukocyte homeostasis GO:0001776 2 0.020
regulation of ras gtpase activity GO:0032318 2 0.020
collagen biosynthetic process GO:0032964 2 0.020
atp catabolic process GO:0006200 4 0.020
protein complex assembly GO:0006461 30 0.020
embryonic skeletal joint morphogenesis GO:0060272 3 0.020
striated muscle cell development GO:0055002 108 0.020
membrane invagination GO:0010324 1 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
cellular biosynthetic process GO:0044249 286 0.019
regulation of homeostatic process GO:0032844 9 0.019
response to hypoxia GO:0001666 25 0.019
response to external stimulus GO:0009605 264 0.019
response to hormone GO:0009725 48 0.019
detection of abiotic stimulus GO:0009582 24 0.019
actin filament based movement GO:0030048 1 0.019
membrane organization GO:0061024 21 0.019
cell matrix adhesion GO:0007160 4 0.018
cell death GO:0008219 121 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
neuronal action potential GO:0019228 18 0.018
nucleotide metabolic process GO:0009117 28 0.018
nuclear transport GO:0051169 4 0.018
leukocyte proliferation GO:0070661 1 0.018
water homeostasis GO:0030104 4 0.018
peptide transport GO:0015833 1 0.018
macromolecule localization GO:0033036 54 0.018
sensory perception of pain GO:0019233 1 0.018
cellular macromolecule localization GO:0070727 21 0.017
positive regulation of secretion GO:0051047 1 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
cell migration involved in heart development GO:0060973 22 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
unidimensional cell growth GO:0009826 5 0.017
growth GO:0040007 174 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
regulation of cell differentiation GO:0045595 142 0.017
cell proliferation GO:0008283 80 0.017
catabolic process GO:0009056 32 0.017
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.017
positive regulation of apoptotic process GO:0043065 29 0.016
anion transport GO:0006820 38 0.016
positive regulation of metabolic process GO:0009893 108 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
regulation of protein complex assembly GO:0043254 3 0.016
positive regulation of cell development GO:0010720 25 0.016
response to oxygen levels GO:0070482 25 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
detection of stimulus GO:0051606 29 0.016
chemical homeostasis GO:0048878 49 0.016
brain development GO:0007420 293 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
cellular response to oxygen levels GO:0071453 1 0.016
cellular catabolic process GO:0044248 27 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
regulation of membrane potential GO:0042391 23 0.015
regulation of heart contraction GO:0008016 32 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
monocarboxylic acid transport GO:0015718 5 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
response to virus GO:0009615 21 0.014
actin filament bundle organization GO:0061572 6 0.014
regulation of cardiac muscle contraction GO:0055117 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
cardiac cell development GO:0055006 21 0.014
cellular response to steroid hormone stimulus GO:0071383 31 0.014
regeneration GO:0031099 91 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.014
cell migration GO:0016477 237 0.014
regulation of apoptotic process GO:0042981 98 0.014
negative regulation of kinase activity GO:0033673 4 0.014
ion transmembrane transport GO:0034220 91 0.014
protein metabolic process GO:0019538 183 0.013
regulation of cell proliferation GO:0042127 37 0.013
protein complex biogenesis GO:0070271 30 0.013
cell cycle GO:0007049 93 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
membrane fusion GO:0061025 2 0.013
response to estrogen GO:0043627 27 0.013
ribonucleotide metabolic process GO:0009259 27 0.013
macromolecular complex assembly GO:0065003 35 0.013
digestive system process GO:0022600 9 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
macromolecule modification GO:0043412 111 0.013
nucleoside metabolic process GO:0009116 11 0.013
response to glucocorticoid GO:0051384 1 0.013
response to lipopolysaccharide GO:0032496 13 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
reactive oxygen species metabolic process GO:0072593 6 0.013
regulation of cellular component biogenesis GO:0044087 12 0.013
response to carbohydrate GO:0009743 3 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
positive regulation of developmental process GO:0051094 50 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
phagocytosis engulfment GO:0006911 1 0.012
establishment of protein localization GO:0045184 14 0.012
actin mediated cell contraction GO:0070252 1 0.012
detection of light stimulus GO:0009583 12 0.012
homeostasis of number of cells GO:0048872 62 0.012
glial cell differentiation GO:0010001 42 0.012
regulation of developmental process GO:0050793 247 0.012
regulation of endothelial cell proliferation GO:0001936 1 0.012
endocardial cushion formation GO:0003272 2 0.012
intestinal absorption GO:0050892 2 0.012
liver development GO:0001889 96 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
purine ribonucleotide metabolic process GO:0009150 27 0.011
urea transport GO:0015840 11 0.011
cardiocyte differentiation GO:0035051 44 0.011
response to inorganic substance GO:0010035 38 0.011
cytoskeleton organization GO:0007010 96 0.011
muscle tissue development GO:0060537 110 0.011
digestion GO:0007586 11 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of protein depolymerization GO:1901879 1 0.011
regulation of actin filament based movement GO:1903115 1 0.011
regulation of cell migration GO:0030334 40 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
cellular response to hypoxia GO:0071456 1 0.011
cellular response to lipid GO:0071396 39 0.011
response to transition metal nanoparticle GO:1990267 28 0.011
response to vitamin GO:0033273 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
protein depolymerization GO:0051261 1 0.011
epidermal cell differentiation GO:0009913 36 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
negative regulation of mitosis GO:0045839 3 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.010
action potential GO:0001508 19 0.010
smooth muscle contraction GO:0006939 2 0.010
positive regulation of ras gtpase activity GO:0032320 1 0.010
t cell differentiation GO:0030217 6 0.010
negative regulation of cell cell adhesion GO:0022408 6 0.010
regulation of glial cell proliferation GO:0060251 4 0.010
single organism cell adhesion GO:0098602 29 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
endomembrane system organization GO:0010256 13 0.010
regulation of muscle contraction GO:0006937 3 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
regulation of rna metabolic process GO:0051252 224 0.010

icn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
disease of metabolism DOID:0014667 0 0.018
amyloidosis DOID:9120 0 0.018
acquired metabolic disease DOID:0060158 0 0.018
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011