Danio rerio

0 known processes

rftn2

raftlin family member 2

(Aliases: zgc:56544,wu:fi98e03)

rftn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular metabolic process GO:0031323 320 0.198
cellular nitrogen compound metabolic process GO:0034641 290 0.123
larval development GO:0002164 2 0.122
regulation of metabolic process GO:0019222 359 0.112
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.110
regulation of nitrogen compound metabolic process GO:0051171 251 0.087
heterocycle metabolic process GO:0046483 290 0.085
macromolecule biosynthetic process GO:0009059 227 0.083
regulation of biological quality GO:0065008 263 0.080
adult behavior GO:0030534 2 0.080
positive regulation of cellular component biogenesis GO:0044089 3 0.079
cellular macromolecule metabolic process GO:0044260 391 0.073
cellular macromolecule biosynthetic process GO:0034645 224 0.071
regulation of macromolecule metabolic process GO:0060255 317 0.071
regulation of primary metabolic process GO:0080090 311 0.069
nitrogen compound metabolic process GO:0006807 319 0.067
locomotion GO:0040011 313 0.062
cell migration GO:0016477 237 0.062
nucleobase containing compound metabolic process GO:0006139 274 0.061
organic cyclic compound metabolic process GO:1901360 301 0.061
signal transduction GO:0007165 455 0.057
regulation of multicellular organismal process GO:0051239 277 0.057
protein metabolic process GO:0019538 183 0.056
cell motility GO:0048870 244 0.055
positive regulation of biological process GO:0048518 253 0.055
heterocycle biosynthetic process GO:0018130 215 0.053
aromatic compound biosynthetic process GO:0019438 217 0.053
transcription dna templated GO:0006351 181 0.050
regulation of rna biosynthetic process GO:2001141 213 0.047
rna metabolic process GO:0016070 219 0.047
gtp metabolic process GO:0046039 4 0.047
cellular component movement GO:0006928 335 0.046
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
single organism localization GO:1902578 225 0.045
response to chemical GO:0042221 320 0.043
regulation of biosynthetic process GO:0009889 250 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.043
maintenance of location GO:0051235 4 0.042
regulation of multicellular organism growth GO:0040014 4 0.042
regulation of transcription dna templated GO:0006355 213 0.042
regulation of epithelial cell proliferation GO:0050678 3 0.042
organic substance biosynthetic process GO:1901576 289 0.042
biosynthetic process GO:0009058 294 0.042
nucleic acid templated transcription GO:0097659 181 0.042
regulation of macromolecule biosynthetic process GO:0010556 225 0.041
nucleic acid metabolic process GO:0090304 244 0.041
meiotic nuclear division GO:0007126 4 0.041
gene expression GO:0010467 252 0.040
regulation of developmental process GO:0050793 247 0.040
positive regulation of metabolic process GO:0009893 108 0.038
guanosine containing compound metabolic process GO:1901068 4 0.038
multicellular organism growth GO:0035264 4 0.037
aging GO:0007568 2 0.037
guanosine containing compound catabolic process GO:1901069 2 0.036
system process GO:0003008 185 0.035
rna biosynthetic process GO:0032774 181 0.035
cellular protein catabolic process GO:0044257 4 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
carboxylic acid metabolic process GO:0019752 22 0.032
cortical actin cytoskeleton organization GO:0030866 1 0.032
response to drug GO:0042493 3 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.032
neuron differentiation GO:0030182 353 0.031
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
regulation of gene expression GO:0010468 265 0.030
nuclear import GO:0051170 3 0.030
macromolecule modification GO:0043412 111 0.030
organic acid metabolic process GO:0006082 31 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
regulation of cellular biosynthetic process GO:0031326 245 0.029
single organism metabolic process GO:0044710 217 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
negative regulation of cellular process GO:0048523 283 0.029
tube morphogenesis GO:0035239 349 0.029
protein dephosphorylation GO:0006470 3 0.029
cellular protein modification process GO:0006464 100 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
positive regulation of catabolic process GO:0009896 4 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028
digestive system development GO:0055123 289 0.028
positive regulation of transport GO:0051050 2 0.028
single organism transport GO:0044765 206 0.028
regulation of cell shape GO:0008360 1 0.027
regulation of binding GO:0051098 3 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
regulation of rna metabolic process GO:0051252 224 0.026
single organism nuclear import GO:1902593 3 0.026
gtp catabolic process GO:0006184 2 0.026
positive regulation of cellular process GO:0048522 201 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
localization of cell GO:0051674 244 0.026
protein import GO:0017038 3 0.025
small molecule metabolic process GO:0044281 77 0.025
cellular amine metabolic process GO:0044106 2 0.025
protein localization to nucleus GO:0034504 3 0.024
homeostatic process GO:0042592 142 0.024
cellular biosynthetic process GO:0044249 286 0.024
cortical cytoskeleton organization GO:0030865 1 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
regulation of molecular function GO:0065009 70 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
regulation of response to stimulus GO:0048583 269 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
regulation of protein catabolic process GO:0042176 1 0.023
negative regulation of kinase activity GO:0033673 4 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
locomotor rhythm GO:0045475 3 0.023
regulation of stem cell proliferation GO:0072091 2 0.023
organelle organization GO:0006996 227 0.023
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.023
negative regulation of ras protein signal transduction GO:0046580 1 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
generation of neurons GO:0048699 385 0.023
peptidyl lysine acetylation GO:0018394 2 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
regulation of protein transport GO:0051223 3 0.022
establishment of localization in cell GO:0051649 77 0.022
regulation of protein targeting GO:1903533 2 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
cell morphogenesis GO:0000902 289 0.022
phagocytosis GO:0006909 3 0.022
regulation of synapse assembly GO:0051963 3 0.021
protein localization to plasma membrane GO:0072659 1 0.021
programmed cell death GO:0012501 119 0.021
amine metabolic process GO:0009308 2 0.021
transport GO:0006810 220 0.021
regulation of protein metabolic process GO:0051246 56 0.021
oxoacid metabolic process GO:0043436 31 0.021
cognition GO:0050890 1 0.021
ribonucleoside monophosphate catabolic process GO:0009158 4 0.021
mitochondrion organization GO:0007005 4 0.021
regulation of cell projection assembly GO:0060491 4 0.021
regulation of signal transduction GO:0009966 225 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.020
negative regulation of biological process GO:0048519 304 0.020
atp catabolic process GO:0006200 4 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
regionalization GO:0003002 274 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
membrane invagination GO:0010324 1 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.019
establishment of localization GO:0051234 244 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
regulation of cell activation GO:0050865 1 0.019
protein targeting to nucleus GO:0044744 3 0.019
developmental growth GO:0048589 166 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
response to organic substance GO:0010033 153 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of phosphate metabolic process GO:0019220 43 0.019
meiotic cell cycle process GO:1903046 3 0.019
cellular protein metabolic process GO:0044267 129 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
glial cell proliferation GO:0014009 4 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
regulation of synapse organization GO:0050807 3 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
lipid storage GO:0019915 1 0.019
positive regulation of map kinase activity GO:0043406 3 0.018
cell cycle GO:0007049 93 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
immune system process GO:0002376 241 0.018
cell death GO:0008219 121 0.018
digestive tract morphogenesis GO:0048546 231 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
mitotic cell cycle GO:0000278 64 0.018
cellular component assembly GO:0022607 170 0.018
regulation of locomotion GO:0040012 55 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
regulation of cell communication GO:0010646 232 0.018
cellular component biogenesis GO:0044085 178 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
protein import into nucleus GO:0006606 3 0.018
apoptotic process GO:0006915 116 0.018
response to external stimulus GO:0009605 264 0.017
response to endogenous stimulus GO:0009719 83 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
cell cycle process GO:0022402 53 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
cytokinesis GO:0000910 3 0.017
protein acylation GO:0043543 3 0.017
wnt signaling pathway GO:0016055 80 0.017
transmembrane transport GO:0055085 120 0.017
regulation of protein complex assembly GO:0043254 3 0.017
cellular response to organic substance GO:0071310 105 0.017
cell projection morphogenesis GO:0048858 244 0.017
adherens junction organization GO:0034332 4 0.017
cellular component morphogenesis GO:0032989 336 0.017
determination of left right symmetry GO:0007368 179 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.017
negative regulation of signaling GO:0023057 96 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
nuclear transport GO:0051169 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
mitotic cell cycle process GO:1903047 48 0.016
stem cell maintenance GO:0019827 4 0.016
regulation of gtpase activity GO:0043087 2 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.016
camera type eye development GO:0043010 222 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
regulation of blood pressure GO:0008217 1 0.016
female sex differentiation GO:0046660 4 0.016
regulation of receptor activity GO:0010469 2 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
stem cell division GO:0017145 1 0.016
regulation of cellular component movement GO:0051270 55 0.016
cell aging GO:0007569 2 0.016
stem cell proliferation GO:0072089 4 0.015
cell migration involved in gastrulation GO:0042074 79 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
protein acetylation GO:0006473 2 0.015
response to stress GO:0006950 263 0.015
regulation of filopodium assembly GO:0051489 2 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
regulation of apoptotic process GO:0042981 98 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
spermatid development GO:0007286 2 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
central nervous system development GO:0007417 387 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
germ line stem cell maintenance GO:0030718 2 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
cell projection organization GO:0030030 284 0.015
developmental programmed cell death GO:0010623 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
cellular response to external stimulus GO:0071496 2 0.014
protein modification process GO:0036211 100 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
actin filament based process GO:0030029 64 0.014
positive regulation of rna biosynthetic process GO:1902680 57 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
cellular ketone metabolic process GO:0042180 11 0.014
response to hexose GO:0009746 3 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
negative regulation of wnt signaling pathway GO:0030178 30 0.014
somatic stem cell maintenance GO:0035019 1 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
apoptotic process involved in development GO:1902742 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
death GO:0016265 121 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
digestive tract development GO:0048565 265 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
centrosome organization GO:0051297 1 0.013
actin filament polymerization GO:0030041 2 0.013
pharyngeal muscle development GO:0043282 4 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
mononuclear cell proliferation GO:0032943 1 0.013
activation of mapk activity GO:0000187 3 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
protein polymerization GO:0051258 4 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
regulation of cytokine production GO:0001817 3 0.013
response to monosaccharide GO:0034284 3 0.013
vasculature development GO:0001944 278 0.013
chemotaxis GO:0006935 104 0.013
regulation of dna templated transcription elongation GO:0032784 3 0.013
response to carbohydrate GO:0009743 3 0.013
cell proliferation GO:0008283 80 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
phosphorus metabolic process GO:0006793 109 0.013
neuron development GO:0048666 262 0.013
cellular response to oxygen levels GO:0071453 1 0.013
regulation of signaling GO:0023051 235 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
positive regulation of catalytic activity GO:0043085 25 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
growth GO:0040007 174 0.013
neuron projection guidance GO:0097485 86 0.012
protein complex disassembly GO:0043241 1 0.012
female gonad development GO:0008585 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
tissue regeneration GO:0042246 74 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
spermatid differentiation GO:0048515 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
autophagy GO:0006914 4 0.012
cell matrix adhesion GO:0007160 4 0.012
tube closure GO:0060606 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
protein stabilization GO:0050821 2 0.012
endosomal transport GO:0016197 2 0.012
response to lipid GO:0033993 60 0.012
regulation of localization GO:0032879 104 0.012
response to uv GO:0009411 3 0.012
muscle cell differentiation GO:0042692 139 0.012
cell projection assembly GO:0030031 64 0.012
chemosensory behavior GO:0007635 1 0.012
cell substrate adhesion GO:0031589 4 0.012
brain development GO:0007420 293 0.012
protein heterooligomerization GO:0051291 1 0.012
chordate embryonic development GO:0043009 271 0.012
regulation of jak stat cascade GO:0046425 3 0.012
tissue remodeling GO:0048771 4 0.012
phagocytosis engulfment GO:0006911 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of cell motility GO:2000145 46 0.012
sequestering of calcium ion GO:0051208 3 0.012
positive regulation of secretion GO:0051047 1 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
regulation of proteolysis GO:0030162 24 0.012
positive regulation of cell cycle GO:0045787 3 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of membrane potential GO:0042391 23 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
positive regulation of translation GO:0045727 1 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
single organism organelle organization GO:1902589 199 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
hormone secretion GO:0046879 2 0.011
response to glucose GO:0009749 3 0.011
response to abiotic stimulus GO:0009628 122 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
somite development GO:0061053 96 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
protein secretion GO:0009306 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
hemopoiesis GO:0030097 183 0.011
sleep GO:0030431 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
heart looping GO:0001947 94 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
positive regulation of molecular function GO:0044093 33 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
meiotic chromosome segregation GO:0045132 3 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
response to vitamin GO:0033273 3 0.011
cellular response to nutrient levels GO:0031669 2 0.011
response to glucocorticoid GO:0051384 1 0.011
cytoskeleton organization GO:0007010 96 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
erythrocyte homeostasis GO:0034101 55 0.011
actin cytoskeleton organization GO:0030036 63 0.011
negative regulation of catabolic process GO:0009895 3 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
intracellular signal transduction GO:0035556 85 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
positive regulation of cell activation GO:0050867 1 0.011
transmission of nerve impulse GO:0019226 19 0.011
lymphocyte proliferation GO:0046651 1 0.011
b cell activation GO:0042113 2 0.011
hormone transport GO:0009914 2 0.011
polarized epithelial cell differentiation GO:0030859 4 0.011
multi organism process GO:0051704 134 0.011
proteolysis GO:0006508 38 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of transporter activity GO:0032409 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
negative regulation of defense response GO:0031348 2 0.010
cellular response to radiation GO:0071478 4 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
protein homooligomerization GO:0051260 3 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
spindle localization GO:0051653 12 0.010
immune system development GO:0002520 191 0.010
urogenital system development GO:0001655 97 0.010
neurological system process GO:0050877 62 0.010
regulation of blood vessel size GO:0050880 2 0.010
regeneration GO:0031099 91 0.010
regulation of organelle assembly GO:1902115 4 0.010
positive regulation of jak stat cascade GO:0046427 2 0.010
dna templated transcription elongation GO:0006354 3 0.010
carbohydrate homeostasis GO:0033500 1 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
cellular component disassembly GO:0022411 1 0.010
skeletal muscle organ development GO:0060538 78 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of cell communication GO:0010648 96 0.010
regulation of transport GO:0051049 45 0.010
positive regulation of leukocyte migration GO:0002687 2 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
neuroblast proliferation GO:0007405 2 0.010
telomere maintenance GO:0000723 1 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
cellular respiration GO:0045333 3 0.010

rftn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.011