Danio rerio

0 known processes

trip13

thyroid hormone receptor interactor 13

(Aliases: MGC65952,im:6901078,zgc:65952)

trip13 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mitotic dna integrity checkpoint GO:0044774 4 0.307
nitrogen compound metabolic process GO:0006807 319 0.286
Mouse
heterocycle metabolic process GO:0046483 290 0.265
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.230
Mouse
response to alkaloid GO:0043279 2 0.187
mitotic g2 m transition checkpoint GO:0044818 3 0.165
cellular biosynthetic process GO:0044249 286 0.164
transcription dna templated GO:0006351 181 0.161
organic cyclic compound metabolic process GO:1901360 301 0.149
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.142
regulation of dna templated transcription in response to stress GO:0043620 0 0.141
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.137
cellular component assembly GO:0022607 170 0.133
Mouse
regulation of metabolic process GO:0019222 359 0.130
macromolecule biosynthetic process GO:0009059 227 0.130
regulation of nitrogen compound metabolic process GO:0051171 251 0.130
mitotic cell cycle embryonic GO:0045448 2 0.127
regulation of nucleic acid templated transcription GO:1903506 213 0.125
cellular nitrogen compound metabolic process GO:0034641 290 0.124
Mouse
dna biosynthetic process GO:0071897 3 0.122
meiotic chromosome segregation GO:0045132 3 0.118
organic cyclic compound biosynthetic process GO:1901362 223 0.116
response to chemical GO:0042221 320 0.114
organic substance biosynthetic process GO:1901576 289 0.114
regulation of cellular metabolic process GO:0031323 320 0.114
nucleobase containing compound biosynthetic process GO:0034654 205 0.112
double strand break repair GO:0006302 3 0.106
Mouse
cell cycle g2 m phase transition GO:0044839 4 0.105
microtubule organizing center organization GO:0031023 1 0.102
regulation of rna metabolic process GO:0051252 224 0.101
negative regulation of nuclear division GO:0051784 3 0.100
nucleobase containing compound metabolic process GO:0006139 274 0.100
Mouse
nucleic acid metabolic process GO:0090304 244 0.098
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.095
Mouse
mitotic g2 dna damage checkpoint GO:0007095 3 0.095
g2 m transition of mitotic cell cycle GO:0000086 4 0.094
organelle organization GO:0006996 227 0.093
Mouse Worm
biosynthetic process GO:0009058 294 0.091
response to stress GO:0006950 263 0.085
Mouse
amine metabolic process GO:0009308 2 0.084
double strand break repair via homologous recombination GO:0000724 1 0.082
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.082
g2 dna damage checkpoint GO:0031572 3 0.082
signal transduction GO:0007165 455 0.082
multicellular organism growth GO:0035264 4 0.081
regulation of gene expression GO:0010468 265 0.080
negative regulation of biological process GO:0048519 304 0.080
positive regulation of cell cycle GO:0045787 3 0.078
regulation of macromolecule metabolic process GO:0060255 317 0.078
meiotic cell cycle process GO:1903046 3 0.077
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.077
meiotic nuclear division GO:0007126 4 0.076
Mouse Worm
cellular response to endogenous stimulus GO:0071495 68 0.074
chromosome organization involved in meiosis GO:0070192 1 0.073
Mouse
regulation of cell cycle GO:0051726 52 0.069
mitotic dna damage checkpoint GO:0044773 4 0.069
maintenance of location GO:0051235 4 0.065
negative regulation of cell division GO:0051782 4 0.064
aging GO:0007568 2 0.063
regulation of transcription dna templated GO:0006355 213 0.062
positive regulation of catabolic process GO:0009896 4 0.062
rna metabolic process GO:0016070 219 0.060
single organism metabolic process GO:0044710 217 0.060
Mouse
cellular amino acid metabolic process GO:0006520 7 0.059
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.058
positive regulation of cellular catabolic process GO:0031331 3 0.057
regulation of cellular ketone metabolic process GO:0010565 7 0.056
intracellular signal transduction GO:0035556 85 0.055
cellular amine metabolic process GO:0044106 2 0.055
regulation of rna biosynthetic process GO:2001141 213 0.055
recombinational repair GO:0000725 1 0.055
cellular protein modification process GO:0006464 100 0.054
regulation of mitotic cell cycle GO:0007346 25 0.053
organic acid metabolic process GO:0006082 31 0.053
regulation of biosynthetic process GO:0009889 250 0.052
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
regulation of multicellular organism growth GO:0040014 4 0.051
negative regulation of cellular process GO:0048523 283 0.051
meiosis i GO:0007127 1 0.050
Mouse
positive regulation of gene expression GO:0010628 71 0.050
blood vessel morphogenesis GO:0048514 216 0.050
negative regulation of biosynthetic process GO:0009890 55 0.050
non recombinational repair GO:0000726 2 0.049
response to drug GO:0042493 3 0.049
positive regulation of biological process GO:0048518 253 0.049
multi organism process GO:0051704 134 0.049
Mouse
dna metabolic process GO:0006259 27 0.049
Mouse
regulation of meiotic cell cycle GO:0051445 1 0.048
centrosome organization GO:0051297 1 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.048
cellular component biogenesis GO:0044085 178 0.048
Mouse
cellular response to radiation GO:0071478 4 0.047
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.047
organonitrogen compound metabolic process GO:1901564 74 0.047
transcription from rna polymerase ii promoter GO:0006366 80 0.046
regulation of cellular biosynthetic process GO:0031326 245 0.045
nucleic acid templated transcription GO:0097659 181 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.045
Worm
peptidyl serine phosphorylation GO:0018105 1 0.045
cellular response to chemical stimulus GO:0070887 157 0.045
response to abiotic stimulus GO:0009628 122 0.045
lipid storage GO:0019915 1 0.044
protein acetylation GO:0006473 2 0.043
cellular response to external stimulus GO:0071496 2 0.043
immune system process GO:0002376 241 0.043
regulation of cellular amine metabolic process GO:0033238 0 0.043
carboxylic acid metabolic process GO:0019752 22 0.043
cellular macromolecule biosynthetic process GO:0034645 224 0.043
negative regulation of macromolecule metabolic process GO:0010605 76 0.043
cell part morphogenesis GO:0032990 246 0.043
heterocycle biosynthetic process GO:0018130 215 0.043
positive regulation of cellular process GO:0048522 201 0.042
modification dependent protein catabolic process GO:0019941 3 0.040
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.040
vasculature development GO:0001944 278 0.040
protein modification process GO:0036211 100 0.040
g1 s transition of mitotic cell cycle GO:0000082 1 0.040
positive regulation of cellular biosynthetic process GO:0031328 68 0.039
regulation of cellular component organization GO:0051128 86 0.039
oxoacid metabolic process GO:0043436 31 0.039
negative regulation of cellular metabolic process GO:0031324 77 0.039
establishment of protein localization to organelle GO:0072594 4 0.038
cytokinesis GO:0000910 3 0.038
protein acylation GO:0043543 3 0.038
regulation of primary metabolic process GO:0080090 311 0.038
positive regulation of metabolic process GO:0009893 108 0.037
histone phosphorylation GO:0016572 2 0.037
response to external stimulus GO:0009605 264 0.036
locomotion GO:0040011 313 0.036
peptidyl serine modification GO:0018209 2 0.036
positive regulation of rna metabolic process GO:0051254 59 0.036
positive regulation of nucleic acid templated transcription GO:1903508 57 0.035
cellular response to organic substance GO:0071310 105 0.035
cell proliferation GO:0008283 80 0.035
regulation of microtubule cytoskeleton organization GO:0070507 3 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.034
positive regulation of rna biosynthetic process GO:1902680 57 0.034
protein metabolic process GO:0019538 183 0.033
single organism organelle organization GO:1902589 199 0.033
Mouse
macromolecule modification GO:0043412 111 0.033
small molecule metabolic process GO:0044281 77 0.033
mitotic cell cycle GO:0000278 64 0.033
specification of axis polarity GO:0065001 4 0.033
peptidyl lysine acetylation GO:0018394 2 0.033
growth GO:0040007 174 0.032
positive regulation of dna metabolic process GO:0051054 1 0.032
regulation of response to stimulus GO:0048583 269 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
sex determination GO:0007530 1 0.032
centrosome duplication GO:0051298 1 0.032
negative regulation of mitotic cell cycle GO:0045930 11 0.032
cell cycle GO:0007049 93 0.032
Mouse Worm
regulation of establishment of protein localization GO:0070201 4 0.031
blood vessel development GO:0001568 246 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
regulation of nuclear division GO:0051783 9 0.031
negative regulation of metabolic process GO:0009892 86 0.031
regulation of protein catabolic process GO:0042176 1 0.031
cellular ketone metabolic process GO:0042180 11 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.030
cell migration GO:0016477 237 0.030
mitotic cell cycle process GO:1903047 48 0.030
negative regulation of protein localization to nucleus GO:1900181 2 0.030
nuclear transport GO:0051169 4 0.030
peptidyl threonine phosphorylation GO:0018107 1 0.029
response to organic substance GO:0010033 153 0.029
positive regulation of biosynthetic process GO:0009891 68 0.029
developmental growth GO:0048589 166 0.028
regulation of mitotic cell cycle phase transition GO:1901990 8 0.028
positive regulation of transcription dna templated GO:0045893 57 0.028
phosphate containing compound metabolic process GO:0006796 108 0.027
establishment of localization GO:0051234 244 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
response to endogenous stimulus GO:0009719 83 0.026
regulation of dna recombination GO:0000018 2 0.026
cellular protein metabolic process GO:0044267 129 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
cell projection organization GO:0030030 284 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.025
protein import into nucleus GO:0006606 3 0.025
cytoskeleton organization GO:0007010 96 0.025
single organism nuclear import GO:1902593 3 0.025
negative regulation of dna metabolic process GO:0051053 4 0.025
dna catabolic process GO:0006308 1 0.025
production of molecular mediator of immune response GO:0002440 2 0.024
dorsal ventral pattern formation GO:0009953 125 0.024
phosphorus metabolic process GO:0006793 109 0.024
gtp metabolic process GO:0046039 4 0.024
rna biosynthetic process GO:0032774 181 0.023
regulation of dna replication GO:0006275 3 0.023
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
regulation of protein transport GO:0051223 3 0.023
negative regulation of transcription dna templated GO:0045892 45 0.023
protein import GO:0017038 3 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
cellular response to organic cyclic compound GO:0071407 38 0.022
larval development GO:0002164 2 0.022
protein polyubiquitination GO:0000209 4 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
nuclear import GO:0051170 3 0.022
regulation of organelle organization GO:0033043 29 0.022
death GO:0016265 121 0.021
Worm
organism emergence from protective structure GO:0071684 4 0.021
peptidyl threonine modification GO:0018210 1 0.021
negative regulation of cell cycle process GO:0010948 9 0.021
negative regulation of protein transport GO:0051224 3 0.021
apoptotic process GO:0006915 116 0.021
Worm
cellular component disassembly GO:0022411 1 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
gene expression GO:0010467 252 0.020
cell cycle process GO:0022402 53 0.020
Mouse
negative regulation of cytoplasmic transport GO:1903650 2 0.020
small gtpase mediated signal transduction GO:0007264 8 0.020
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 1 0.020
cell morphogenesis GO:0000902 289 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.019
response to uv GO:0009411 3 0.019
regulation of protein complex assembly GO:0043254 3 0.019
cellular response to stress GO:0033554 62 0.019
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
gtp catabolic process GO:0006184 2 0.019
interspecies interaction between organisms GO:0044419 4 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
response to organic cyclic compound GO:0014070 51 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
adult behavior GO:0030534 2 0.019
hatching GO:0035188 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of cell cycle g2 m phase transition GO:1902749 4 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
regulation of localization GO:0032879 104 0.018
fertilization GO:0009566 3 0.018
regulation of mitosis GO:0007088 9 0.018
cell projection morphogenesis GO:0048858 244 0.018
cellular response to dna damage stimulus GO:0006974 24 0.018
Mouse
regulation of stem cell proliferation GO:0072091 2 0.017
dna damage checkpoint GO:0000077 6 0.017
cellular component movement GO:0006928 335 0.017
angiogenesis GO:0001525 158 0.017
regulation of cell communication GO:0010646 232 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
ras protein signal transduction GO:0007265 7 0.017
phagocytosis GO:0006909 3 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
reciprocal dna recombination GO:0035825 1 0.017
Mouse
cellular response to light stimulus GO:0071482 4 0.017
regulation of cell cycle phase transition GO:1901987 8 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
macromolecular complex disassembly GO:0032984 1 0.016
protein localization to nucleus GO:0034504 3 0.016
mitotic cytokinesis GO:0000281 3 0.016
regulation of cell cycle process GO:0010564 20 0.016
negative regulation of intracellular protein transport GO:0090317 3 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
transport GO:0006810 220 0.016
regulation of biological quality GO:0065008 263 0.015
regulation of gtpase activity GO:0043087 2 0.015
central nervous system development GO:0007417 387 0.015
chromatin organization GO:0006325 22 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
negative regulation of cell cycle GO:0045786 14 0.015
mitotic nuclear division GO:0007067 18 0.015
intestinal cholesterol absorption GO:0030299 2 0.015
positive regulation of histone modification GO:0031058 1 0.015
protein targeting to nucleus GO:0044744 3 0.014
positive regulation of transport GO:0051050 2 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
female gamete generation GO:0007292 14 0.014
Mouse
organelle assembly GO:0070925 110 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
male meiosis GO:0007140 2 0.014
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
cellular protein catabolic process GO:0044257 4 0.013
regulation of signaling GO:0023051 235 0.013
protein phosphorylation GO:0006468 47 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of protein targeting GO:1903533 2 0.013
atp catabolic process GO:0006200 4 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
embryonic organ development GO:0048568 381 0.013
morphogenesis of an epithelium GO:0002009 333 0.012
regulation of circadian rhythm GO:0042752 4 0.012
protein complex disassembly GO:0043241 1 0.012
multicellular organism reproduction GO:0032504 35 0.012
Mouse
cell death GO:0008219 121 0.012
Worm
negative regulation of protein import into nucleus GO:0042308 2 0.012
leukocyte proliferation GO:0070661 1 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
developmental programmed cell death GO:0010623 4 0.012
regulation of cell proliferation GO:0042127 37 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
regionalization GO:0003002 274 0.012
regulation of protein metabolic process GO:0051246 56 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
Mouse
protein polymerization GO:0051258 4 0.012
negative regulation of mitosis GO:0045839 3 0.012
chromosome organization GO:0051276 31 0.012
Mouse
regulation of protein binding GO:0043393 3 0.012
b cell activation GO:0042113 2 0.011
cell motility GO:0048870 244 0.011
membrane invagination GO:0010324 1 0.011
regulation of organelle assembly GO:1902115 4 0.011
negative regulation of cellular component organization GO:0051129 16 0.011
programmed cell death GO:0012501 119 0.011
Worm
negative regulation of protein phosphorylation GO:0001933 4 0.011
vesicle mediated transport GO:0016192 22 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
stem cell division GO:0017145 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
macromolecular complex assembly GO:0065003 35 0.011
stem cell proliferation GO:0072089 4 0.011
heart development GO:0007507 313 0.011
reproduction GO:0000003 40 0.011
Mouse Worm
cellular localization GO:0051641 97 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of apoptotic process GO:0042981 98 0.011
regulation of cell division GO:0051302 12 0.011
developmental process involved in reproduction GO:0003006 27 0.011
Mouse
single organism reproductive process GO:0044702 40 0.011
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.011
development of primary female sexual characteristics GO:0046545 4 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
response to mechanical stimulus GO:0009612 24 0.010
response to radiation GO:0009314 51 0.010
mitotic cell cycle phase transition GO:0044772 9 0.010
regulation of dna metabolic process GO:0051052 11 0.010
determination of bilateral symmetry GO:0009855 204 0.010
primary neural tube formation GO:0014020 1 0.010
phosphorylation GO:0016310 69 0.010
rna localization GO:0006403 4 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010

trip13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.053
disease of cellular proliferation DOID:14566 0 0.053
disease of anatomical entity DOID:7 0 0.048
organ system cancer DOID:0050686 0 0.036
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.013
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
breast cancer DOID:1612 0 0.011
thoracic cancer DOID:5093 0 0.011
inherited metabolic disorder DOID:655 0 0.011