Danio rerio

0 known processes

evla

Enah/Vasp-like a

(Aliases: id:ibd2260,Evl,zgc:65883,zgc:77388)

evla biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.318
Worm Fly
neuron differentiation GO:0030182 353 0.180
Worm Fly
cell part morphogenesis GO:0032990 246 0.123
Worm Fly
meiosis i GO:0007127 1 0.116
immune system process GO:0002376 241 0.111
organelle organization GO:0006996 227 0.102
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.092
Worm Fly
meiotic cell cycle process GO:1903046 3 0.091
meiotic nuclear division GO:0007126 4 0.091
cytoskeleton organization GO:0007010 96 0.087
Human Mouse Fly
larval development GO:0002164 2 0.087
glycoprotein biosynthetic process GO:0009101 21 0.084
regulation of reproductive process GO:2000241 4 0.083
aging GO:0007568 2 0.072
regulation of cell communication GO:0010646 232 0.068
Zebrafish
neuron development GO:0048666 262 0.066
Worm Fly
cell projection morphogenesis GO:0048858 244 0.064
Worm Fly
digestive system development GO:0055123 289 0.063
single organism nuclear import GO:1902593 3 0.063
proteasomal protein catabolic process GO:0010498 2 0.062
cellular macromolecule biosynthetic process GO:0034645 224 0.057
single organism organelle organization GO:1902589 199 0.057
Human Mouse Fly
leukocyte proliferation GO:0070661 1 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.052
cellular nitrogen compound metabolic process GO:0034641 290 0.052
protein localization to plasma membrane GO:0072659 1 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.050
Worm Fly
cell projection organization GO:0030030 284 0.048
Human Worm Fly
phagocytosis engulfment GO:0006911 1 0.048
multicellular organismal metabolic process GO:0044236 2 0.048
maintenance of location GO:0051235 4 0.047
protein import into nucleus GO:0006606 3 0.047
response to drug GO:0042493 3 0.046
regulation of membrane potential GO:0042391 23 0.045
cellular protein catabolic process GO:0044257 4 0.044
protein targeting to nucleus GO:0044744 3 0.043
morphogenesis of an epithelium GO:0002009 333 0.042
Fly
multicellular organism growth GO:0035264 4 0.042
mitochondrion organization GO:0007005 4 0.042
lipid storage GO:0019915 1 0.041
death GO:0016265 121 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
regulation of biological quality GO:0065008 263 0.039
Mouse Fly
nuclear import GO:0051170 3 0.039
hepaticobiliary system development GO:0061008 98 0.039
multicellular organismal signaling GO:0035637 22 0.038
macromolecular complex subunit organization GO:0043933 74 0.038
Human Mouse Fly
cellular protein metabolic process GO:0044267 129 0.038
mononuclear cell proliferation GO:0032943 1 0.038
neuron projection development GO:0031175 180 0.037
Worm Fly
regulation of response to stimulus GO:0048583 269 0.037
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.036
inner ear development GO:0048839 126 0.036
ear development GO:0043583 127 0.036
positive regulation of macromolecule metabolic process GO:0010604 93 0.035
gtp metabolic process GO:0046039 4 0.035
regulation of multicellular organismal development GO:2000026 223 0.035
Fly
adult behavior GO:0030534 2 0.035
protein metabolic process GO:0019538 183 0.034
muscle structure development GO:0061061 196 0.034
signal transduction GO:0007165 455 0.034
Zebrafish
gtp catabolic process GO:0006184 2 0.034
single fertilization GO:0007338 3 0.033
regulation of signaling GO:0023051 235 0.033
Zebrafish
tube morphogenesis GO:0035239 349 0.033
dna templated transcription elongation GO:0006354 3 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
guanosine containing compound metabolic process GO:1901068 4 0.033
phagocytosis GO:0006909 3 0.033
locomotion GO:0040011 313 0.033
Human Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
cell motility GO:0048870 244 0.032
Human Worm Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
regulation of striated muscle contraction GO:0006942 2 0.031
oocyte anterior posterior axis specification GO:0007314 4 0.031
cell death GO:0008219 121 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
modification dependent protein catabolic process GO:0019941 3 0.030
regulation of protein transport GO:0051223 3 0.030
response to biotic stimulus GO:0009607 97 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
regulation of protein catabolic process GO:0042176 1 0.030
regulation of intracellular protein transport GO:0033157 3 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
phosphorus metabolic process GO:0006793 109 0.029
single organism localization GO:1902578 225 0.029
Fly
regulation of cell activation GO:0050865 1 0.029
sensory organ development GO:0007423 393 0.029
Fly
regulation of signal transduction GO:0009966 225 0.029
Zebrafish
cellular localization GO:0051641 97 0.029
Fly
muscle cell differentiation GO:0042692 139 0.029
cell migration GO:0016477 237 0.028
Human Worm Fly
circulatory system process GO:0003013 87 0.028
negative regulation of biological process GO:0048519 304 0.028
Human Fly
positive regulation of catabolic process GO:0009896 4 0.028
regulation of ion transmembrane transporter activity GO:0032412 2 0.028
positive regulation of transport GO:0051050 2 0.028
cellular component movement GO:0006928 335 0.028
Human Worm Fly
hatching gland development GO:0048785 3 0.028
embryo development ending in birth or egg hatching GO:0009792 271 0.028
Fly
regulation of multicellular organism growth GO:0040014 4 0.027
neuron projection morphogenesis GO:0048812 161 0.027
Worm Fly
phosphate containing compound metabolic process GO:0006796 108 0.027
regulation of muscle contraction GO:0006937 3 0.027
regulation of reactive oxygen species metabolic process GO:2000377 2 0.027
cell morphogenesis GO:0000902 289 0.027
Worm Fly
axis specification GO:0009798 43 0.026
axonogenesis GO:0007409 152 0.026
Worm Fly
cellular response to starvation GO:0009267 1 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
cell morphogenesis involved in differentiation GO:0000904 195 0.025
Worm Fly
regulation of cell shape GO:0008360 1 0.025
Fly
maternal determination of anterior posterior axis embryo GO:0008358 4 0.025
peptide metabolic process GO:0006518 1 0.025
multi organism process GO:0051704 134 0.025
Fly
semicircular canal development GO:0060872 24 0.025
organic substance biosynthetic process GO:1901576 289 0.025
protein localization to nucleus GO:0034504 3 0.024
regulation of anatomical structure morphogenesis GO:0022603 130 0.024
Fly
positive regulation of metabolic process GO:0009893 108 0.024
positive regulation of gene expression GO:0010628 71 0.024
blood circulation GO:0008015 87 0.024
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.024
cellular biosynthetic process GO:0044249 286 0.024
localization of cell GO:0051674 244 0.023
Human Worm Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.023
fertilization GO:0009566 3 0.023
wound healing GO:0042060 90 0.023
cellular component assembly GO:0022607 170 0.023
Human Mouse Fly
ventricular cardiac muscle tissue development GO:0003229 3 0.023
digestive tract development GO:0048565 265 0.023
response to external biotic stimulus GO:0043207 97 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
growth GO:0040007 174 0.023
Fly
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.022
myeloid cell differentiation GO:0030099 86 0.022
cytokinesis GO:0000910 3 0.022
eye development GO:0001654 277 0.022
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of apoptotic process GO:0042981 98 0.021
spermatid differentiation GO:0048515 2 0.021
apoptotic process GO:0006915 116 0.021
transcription dna templated GO:0006351 181 0.021
regulation of cell death GO:0010941 103 0.021
protein modification process GO:0036211 100 0.021
single organism metabolic process GO:0044710 217 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
cardiac conduction GO:0061337 3 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
heterocycle metabolic process GO:0046483 290 0.021
glycosylation GO:0070085 11 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
negative regulation of reproductive process GO:2000242 3 0.020
reproduction GO:0000003 40 0.020
Fly
cellular response to oxygen levels GO:0071453 1 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
regeneration GO:0031099 91 0.020
Worm
gastrulation GO:0007369 208 0.020
cellular response to nutrient levels GO:0031669 2 0.020
nuclear transport GO:0051169 4 0.020
protein import GO:0017038 3 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
membrane invagination GO:0010324 1 0.020
regulation of nervous system development GO:0051960 90 0.019
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
Mouse
transport GO:0006810 220 0.019
Fly
establishment of localization in cell GO:0051649 77 0.019
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
regulation of cell development GO:0060284 100 0.019
cell cell recognition GO:0009988 1 0.019
cell proliferation GO:0008283 80 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.019
rna localization GO:0006403 4 0.019
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.019
regulation of tube size GO:0035150 2 0.019
membrane organization GO:0061024 21 0.018
hemopoiesis GO:0030097 183 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
single organism transport GO:0044765 206 0.018
Fly
erythrocyte homeostasis GO:0034101 55 0.018
startle response GO:0001964 4 0.018
nitric oxide metabolic process GO:0046209 2 0.018
nuclear export GO:0051168 1 0.018
action potential GO:0001508 19 0.018
lymphocyte proliferation GO:0046651 1 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
autophagy GO:0006914 4 0.018
positive regulation of cell cycle GO:0045787 3 0.018
organelle assembly GO:0070925 110 0.018
regulation of system process GO:0044057 40 0.018
response to stress GO:0006950 263 0.018
Worm
convergent extension GO:0060026 118 0.018
macromolecule biosynthetic process GO:0009059 227 0.017
axon development GO:0061564 166 0.017
Worm Fly
macromolecule modification GO:0043412 111 0.017
biosynthetic process GO:0009058 294 0.017
endoderm development GO:0007492 49 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
protein polymerization GO:0051258 4 0.017
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
cellular response to external stimulus GO:0071496 2 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
cytoplasm organization GO:0007028 4 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
cranial nerve development GO:0021545 42 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
cellular component disassembly GO:0022411 1 0.017
cellular component biogenesis GO:0044085 178 0.017
Human Mouse Fly
epithelial cell differentiation GO:0030855 116 0.016
Fly
regulation of cardiac muscle contraction GO:0055117 2 0.016
pole plasm assembly GO:0007315 4 0.016
single organism reproductive process GO:0044702 40 0.016
Fly
developmental growth GO:0048589 166 0.016
Fly
regulation of rho protein signal transduction GO:0035023 2 0.016
neuronal action potential GO:0019228 18 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
Human Fly
oxoacid metabolic process GO:0043436 31 0.016
positive regulation of biological process GO:0048518 253 0.016
Human Mouse Fly
actin filament based process GO:0030029 64 0.016
Human Mouse Fly
regulation of developmental process GO:0050793 247 0.016
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.016
programmed cell death GO:0012501 119 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
positive regulation of immune effector process GO:0002699 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
response to ketone GO:1901654 1 0.015
anatomical structure arrangement GO:0048532 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of protein metabolic process GO:0051246 56 0.015
establishment of endothelial barrier GO:0061028 3 0.015
neuron projection guidance GO:0097485 86 0.015
Worm Fly
production of molecular mediator of immune response GO:0002440 2 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
regulation of intracellular ph GO:0051453 1 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
Fly
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
stem cell fate commitment GO:0048865 1 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of protein targeting GO:1903533 2 0.015
sensory organ morphogenesis GO:0090596 200 0.015
post embryonic organ development GO:0048569 4 0.015
establishment of protein localization to organelle GO:0072594 4 0.014
embryonic organ development GO:0048568 381 0.014
cellular amide metabolic process GO:0043603 4 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.014
nitric oxide biosynthetic process GO:0006809 2 0.014
sexual reproduction GO:0019953 36 0.014
Fly
organic acid metabolic process GO:0006082 31 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
head development GO:0060322 303 0.014
lipid homeostasis GO:0055088 3 0.014
spermatid development GO:0007286 2 0.014
regionalization GO:0003002 274 0.014
Fly
tissue regeneration GO:0042246 74 0.014
protein targeting to membrane GO:0006612 1 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of cell differentiation GO:0045595 142 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
homeostatic process GO:0042592 142 0.013
heart contraction GO:0060047 71 0.013
regulation of cellular ph GO:0030641 1 0.013
phosphorylation GO:0016310 69 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
blood vessel morphogenesis GO:0048514 216 0.013
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
defense response to fungus GO:0050832 2 0.013
glycoprotein metabolic process GO:0009100 23 0.013
proximal distal pattern formation GO:0009954 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
reproductive process GO:0022414 40 0.013
Fly
b cell activation GO:0042113 2 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
Zebrafish
endoderm formation GO:0001706 29 0.013
collagen metabolic process GO:0032963 2 0.013
defense response GO:0006952 47 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of gene expression GO:0010468 265 0.013
regulation of blood vessel size GO:0050880 2 0.013
negative regulation of signal transduction GO:0009968 94 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
negative regulation of cytokine production GO:0001818 1 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
nucleic acid templated transcription GO:0097659 181 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
female gonad development GO:0008585 4 0.012
meiotic chromosome segregation GO:0045132 3 0.012
anterior posterior pattern specification GO:0009952 152 0.012
Fly
response to other organism GO:0051707 97 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
regulation of ph GO:0006885 3 0.012
amine metabolic process GO:0009308 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of protein complex assembly GO:0043254 3 0.012
Mouse
regulation of programmed cell death GO:0043067 101 0.012
stem cell maintenance GO:0019827 4 0.012
negative regulation of autophagy GO:0010507 1 0.012
hindbrain development GO:0030902 91 0.012
response to glucocorticoid GO:0051384 1 0.012
camera type eye morphogenesis GO:0048593 108 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
rhombomere 5 development GO:0021571 4 0.012
regulation of protein polymerization GO:0032271 2 0.012
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
regulation of autophagy GO:0010506 3 0.012
positive regulation of dna templated transcription elongation GO:0032786 1 0.012
multicellular organism reproduction GO:0032504 35 0.011
Fly
negative regulation of multi organism process GO:0043901 3 0.011
skeletal system morphogenesis GO:0048705 102 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
astrocyte differentiation GO:0048708 1 0.011
rna metabolic process GO:0016070 219 0.011
stem cell proliferation GO:0072089 4 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of molecular function GO:0065009 70 0.011
regulation of catalytic activity GO:0050790 55 0.011
regulation of myotube differentiation GO:0010830 2 0.011
small molecule metabolic process GO:0044281 77 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
protein complex disassembly GO:0043241 1 0.011
transmission of nerve impulse GO:0019226 19 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
protein stabilization GO:0050821 2 0.011
positive regulation of multi organism process GO:0043902 3 0.011
cellular protein modification process GO:0006464 100 0.011
estrogen metabolic process GO:0008210 2 0.011
protein phosphorylation GO:0006468 47 0.011
regulation of cytokine production GO:0001817 3 0.011
heart development GO:0007507 313 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
cognition GO:0050890 1 0.011
regulation of ectodermal cell fate specification GO:0042665 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
microtubule organizing center organization GO:0031023 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
negative regulation of developmental process GO:0051093 65 0.011
Fly
immunoglobulin mediated immune response GO:0016064 3 0.011
immune system development GO:0002520 191 0.011
system process GO:0003008 185 0.011
cellular amine metabolic process GO:0044106 2 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
protein homooligomerization GO:0051260 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
axon ensheathment GO:0008366 18 0.010
regulation of synapse assembly GO:0051963 3 0.010
Fly
neuroblast differentiation GO:0014016 1 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
centrosome cycle GO:0007098 1 0.010
muscle cell development GO:0055001 115 0.010
embryonic skeletal joint morphogenesis GO:0060272 3 0.010
rna biosynthetic process GO:0032774 181 0.010
neural crest cell migration GO:0001755 42 0.010
morphogenesis of an epithelial sheet GO:0002011 49 0.010
regulation of metabolic process GO:0019222 359 0.010
regulation of neurogenesis GO:0050767 87 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
Human Mouse
proteolysis GO:0006508 38 0.010
muscle tissue development GO:0060537 110 0.010

evla disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.011