Danio rerio

69 known processes

otx5

orthodenticle homolog 5

(Aliases: cb828)

otx5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.962
Zebrafish Worm Fly
circadian rhythm GO:0007623 19 0.927
rhythmic process GO:0048511 21 0.924
neuron development GO:0048666 262 0.921
Zebrafish Fly
neuron differentiation GO:0030182 353 0.889
Zebrafish Worm Fly
central nervous system development GO:0007417 387 0.878
Zebrafish Fly
retina development in camera type eye GO:0060041 146 0.830
Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.812
circadian regulation of gene expression GO:0032922 8 0.794
photoreceptor cell development GO:0042461 40 0.775
Zebrafish Fly
retina morphogenesis in camera type eye GO:0060042 79 0.773
hindbrain development GO:0030902 91 0.754
Zebrafish
eye morphogenesis GO:0048592 144 0.753
Zebrafish Fly
eye development GO:0001654 277 0.753
Zebrafish Mouse Fly
sensory organ development GO:0007423 393 0.740
Zebrafish Mouse Fly
sensory organ morphogenesis GO:0090596 200 0.739
Zebrafish Fly
negative regulation of biological process GO:0048519 304 0.723
Zebrafish Fly
absorption of visible light GO:0016038 2 0.713
regulation of gene expression GO:0010468 265 0.712
cellular biosynthetic process GO:0044249 286 0.698
neuron fate specification GO:0048665 20 0.691
Worm
regulation of transcription dna templated GO:0006355 213 0.675
nucleobase containing compound biosynthetic process GO:0034654 205 0.663
gene expression GO:0010467 252 0.655
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.650
neuron projection development GO:0031175 180 0.646
Fly
cellular component movement GO:0006928 335 0.630
regulation of multicellular organismal development GO:2000026 223 0.630
Zebrafish Fly
regulation of rna metabolic process GO:0051252 224 0.625
cellular component morphogenesis GO:0032989 336 0.624
Fly
brain development GO:0007420 293 0.608
Zebrafish Fly
cell part morphogenesis GO:0032990 246 0.600
Fly
camera type eye development GO:0043010 222 0.595
Zebrafish Mouse
behavior GO:0007610 74 0.578
Worm
regulation of biological quality GO:0065008 263 0.577
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.571
Fly
photoreceptor cell fate commitment GO:0046552 1 0.562
Fly
response to light stimulus GO:0009416 46 0.558
regulation of axon guidance GO:1902667 8 0.557
eye photoreceptor cell differentiation GO:0001754 45 0.553
Zebrafish Fly
cell morphogenesis GO:0000902 289 0.547
Fly
digestive tract development GO:0048565 265 0.543
regulation of metabolic process GO:0019222 359 0.538
negative regulation of cellular process GO:0048523 283 0.534
Zebrafish Fly
gastrulation GO:0007369 208 0.525
neural retina development GO:0003407 49 0.510
regulation of localization GO:0032879 104 0.492
chemotaxis GO:0006935 104 0.487
cell projection morphogenesis GO:0048858 244 0.484
Fly
regulation of multicellular organismal process GO:0051239 277 0.480
Zebrafish Fly
response to abiotic stimulus GO:0009628 122 0.478
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.467
chemosensory behavior GO:0007635 1 0.462
Worm
gland development GO:0048732 143 0.453
regulation of axon extension GO:0030516 24 0.448
neuron projection guidance GO:0097485 86 0.444
eye photoreceptor cell development GO:0042462 30 0.428
Zebrafish Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.422
biosynthetic process GO:0009058 294 0.414
photoreceptor cell differentiation GO:0046530 55 0.401
Zebrafish Fly
head development GO:0060322 303 0.389
Zebrafish Fly
regulation of cell differentiation GO:0045595 142 0.389
Zebrafish Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.383
Fly
cell growth GO:0016049 57 0.381
cell projection organization GO:0030030 284 0.379
Fly
response to radiation GO:0009314 51 0.373
system process GO:0003008 185 0.365
Zebrafish Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.359
hematopoietic or lymphoid organ development GO:0048534 191 0.349
nucleic acid metabolic process GO:0090304 244 0.346
regulation of circadian sleep wake cycle GO:0042749 1 0.345
developmental programmed cell death GO:0010623 4 0.342
Zebrafish
sensory perception of chemical stimulus GO:0007606 3 0.336
Worm
phototransduction visible light GO:0007603 2 0.336
neuron projection morphogenesis GO:0048812 161 0.329
Fly
regulation of cell communication GO:0010646 232 0.309
localization of cell GO:0051674 244 0.308
camera type eye photoreceptor cell differentiation GO:0060219 19 0.307
regulation of signaling GO:0023051 235 0.303
regulation of axonogenesis GO:0050770 32 0.301
response to external stimulus GO:0009605 264 0.299
nitrogen compound metabolic process GO:0006807 319 0.298
regulation of cell development GO:0060284 100 0.298
Zebrafish Fly
ameboidal type cell migration GO:0001667 143 0.285
positive regulation of cellular process GO:0048522 201 0.279
cellular nitrogen compound metabolic process GO:0034641 290 0.279
regulation of nucleic acid templated transcription GO:1903506 213 0.271
nucleobase containing compound metabolic process GO:0006139 274 0.271
rna biosynthetic process GO:0032774 181 0.257
homeostatic process GO:0042592 142 0.256
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.256
Human Mouse Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.251
regulation of neurogenesis GO:0050767 87 0.249
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.249
Human Mouse Worm Fly
axonogenesis GO:0007409 152 0.237
heterocycle biosynthetic process GO:0018130 215 0.233
regulation of biosynthetic process GO:0009889 250 0.233
taxis GO:0042330 109 0.231
immune system process GO:0002376 241 0.221
regulation of extent of cell growth GO:0061387 29 0.214
positive regulation of rna metabolic process GO:0051254 59 0.210
regionalization GO:0003002 274 0.209
Zebrafish Fly
axon extension GO:0048675 45 0.207
neuron fate commitment GO:0048663 26 0.207
Worm Fly
brain segmentation GO:0035284 6 0.206
Fly
immune system development GO:0002520 191 0.206
fin development GO:0033333 77 0.205
regulation of nervous system development GO:0051960 90 0.203
Fly
locomotion GO:0040011 313 0.202
cellular response to chemical stimulus GO:0070887 157 0.201
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.198
axon development GO:0061564 166 0.195
regulation of circadian rhythm GO:0042752 4 0.194
regulation of cellular metabolic process GO:0031323 320 0.194
positive regulation of biological process GO:0048518 253 0.191
organic cyclic compound biosynthetic process GO:1901362 223 0.191
regulation of neuron differentiation GO:0045664 56 0.188
Fly
regulation of axon extension involved in axon guidance GO:0048841 6 0.185
cell migration involved in gastrulation GO:0042074 79 0.182
axon guidance GO:0007411 86 0.180
septum transversum development GO:0003343 4 0.179
transcription dna templated GO:0006351 181 0.176
appendage development GO:0048736 80 0.175
auditory receptor cell fate determination GO:0042668 2 0.175
neuron projection extension GO:1990138 45 0.174
cell surface receptor signaling pathway GO:0007166 325 0.173
cellular macromolecule biosynthetic process GO:0034645 224 0.173
regulation of anatomical structure morphogenesis GO:0022603 130 0.172
Zebrafish Fly
heterocycle metabolic process GO:0046483 290 0.172
positive regulation of rna biosynthetic process GO:1902680 57 0.172
retinal cone cell development GO:0046549 8 0.172
single organism localization GO:1902578 225 0.171
digestive system development GO:0055123 289 0.169
cellular macromolecule metabolic process GO:0044260 391 0.169
regulation of cellular biosynthetic process GO:0031326 245 0.169
photoperiodism GO:0009648 11 0.168
response to stress GO:0006950 263 0.168
developmental cell growth GO:0048588 52 0.168
regulation of signal transduction GO:0009966 225 0.167
detection of stimulus GO:0051606 29 0.166
camera type eye morphogenesis GO:0048593 108 0.166
stem cell division GO:0017145 1 0.166
negative regulation of metabolic process GO:0009892 86 0.163
Fly
response to lipid GO:0033993 60 0.162
regulation of cell size GO:0008361 29 0.160
establishment of localization GO:0051234 244 0.160
regulation of nitrogen compound metabolic process GO:0051171 251 0.158
organic substance biosynthetic process GO:1901576 289 0.158
cellular response to radiation GO:0071478 4 0.152
vasculature development GO:0001944 278 0.149
response to hormone GO:0009725 48 0.148
maintenance of location GO:0051235 4 0.146
fin morphogenesis GO:0033334 53 0.146
rna metabolic process GO:0016070 219 0.144
regulation of anatomical structure size GO:0090066 33 0.144
regulation of behavior GO:0050795 24 0.143
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.142
negative regulation of rna metabolic process GO:0051253 48 0.141
Fly
developmental growth involved in morphogenesis GO:0060560 86 0.139
nucleic acid templated transcription GO:0097659 181 0.138
retinal cone cell differentiation GO:0042670 12 0.138
midbrain development GO:0030901 28 0.138
Zebrafish
lateral line system development GO:0048925 76 0.137
positive regulation of developmental process GO:0051094 50 0.137
Fly
response to drug GO:0042493 3 0.137
proepicardium development GO:0003342 4 0.135
hemopoiesis GO:0030097 183 0.134
retina layer formation GO:0010842 24 0.132
response to oxygen containing compound GO:1901700 55 0.132
Zebrafish
hindbrain morphogenesis GO:0021575 22 0.131
cell fate commitment GO:0045165 99 0.129
Worm Fly
sequestering of calcium ion GO:0051208 3 0.129
regulation of chemotaxis GO:0050920 18 0.128
negative regulation of cell communication GO:0010648 96 0.128
regulation of neuron projection development GO:0010975 40 0.126
inner ear morphogenesis GO:0042472 63 0.121
lateral line development GO:0048882 66 0.121
positive regulation of multicellular organismal process GO:0051240 52 0.120
Fly
macromolecule biosynthetic process GO:0009059 227 0.117
enzyme linked receptor protein signaling pathway GO:0007167 106 0.116
positive regulation of cellular biosynthetic process GO:0031328 68 0.115
sensory system development GO:0048880 76 0.115
endocardium formation GO:0060214 1 0.115
cellular response to light stimulus GO:0071482 4 0.113
developmental growth GO:0048589 166 0.113
positive regulation of macromolecule metabolic process GO:0010604 93 0.113
digestive tract morphogenesis GO:0048546 231 0.113
embryonic pectoral fin morphogenesis GO:0035118 24 0.108
intracellular signal transduction GO:0035556 85 0.107
inner ear development GO:0048839 126 0.105
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.104
response to chemical GO:0042221 320 0.102
Zebrafish Worm
locomotor rhythm GO:0045475 3 0.102
liver development GO:0001889 96 0.102
response to acid chemical GO:0001101 17 0.101
cell proliferation GO:0008283 80 0.101
transmission of nerve impulse GO:0019226 19 0.098
positive regulation of nervous system development GO:0051962 25 0.098
Fly
response to wounding GO:0009611 116 0.094
single organismal cell cell adhesion GO:0016337 29 0.092
ventral spinal cord development GO:0021517 35 0.092
cell fate specification GO:0001708 68 0.091
Worm
aging GO:0007568 2 0.091
regulation of cell growth GO:0001558 29 0.090
pectoral fin development GO:0033339 50 0.089
regulation of establishment of protein localization GO:0070201 4 0.089
erythrocyte differentiation GO:0030218 54 0.088
glial cell differentiation GO:0010001 42 0.087
positive regulation of cell differentiation GO:0045597 30 0.087
Fly
larval development GO:0002164 2 0.086
positive regulation of biosynthetic process GO:0009891 68 0.085
cell migration GO:0016477 237 0.085
positive regulation of axon extension GO:0045773 5 0.085
biological adhesion GO:0022610 40 0.083
angiogenesis GO:0001525 158 0.083
visual perception GO:0007601 17 0.083
Zebrafish
epithelial cell development GO:0002064 42 0.083
regulation of cellular component organization GO:0051128 86 0.083
pharyngeal system development GO:0060037 18 0.082
rhythmic behavior GO:0007622 5 0.082
regulation of growth GO:0040008 42 0.081
sensory perception GO:0007600 39 0.081
Zebrafish Worm
blood vessel development GO:0001568 246 0.081
cell motility GO:0048870 244 0.081
regulation of cellular component movement GO:0051270 55 0.080
intracellular estrogen receptor signaling pathway GO:0030520 3 0.080
olfactory lobe development GO:0021988 4 0.079
pancreatic a cell development GO:0003322 2 0.079
regeneration GO:0031099 91 0.077
endocardium morphogenesis GO:0003160 4 0.075
regulation of cell migration GO:0030334 40 0.075
gastrulation with mouth forming second GO:0001702 44 0.074
signal transduction GO:0007165 455 0.074
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.071
neuron fate determination GO:0048664 2 0.070
polarized epithelial cell differentiation GO:0030859 4 0.070
endocrine system development GO:0035270 65 0.069
cellular aromatic compound metabolic process GO:0006725 295 0.069
inner ear receptor cell fate commitment GO:0060120 4 0.069
regulation of primary metabolic process GO:0080090 311 0.068
regulation of cell motility GO:2000145 46 0.068
negative regulation of macromolecule metabolic process GO:0010605 76 0.067
Fly
response to alkaloid GO:0043279 2 0.065
forebrain development GO:0030900 96 0.065
neuroblast fate commitment GO:0014017 1 0.064
neurological system process GO:0050877 62 0.064
Zebrafish Worm
negative regulation of gene expression GO:0010629 65 0.063
Fly
negative regulation of signaling GO:0023057 96 0.063
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.062
transport GO:0006810 220 0.062
defense response GO:0006952 47 0.061
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.061
Human Mouse Worm Fly
response to organic substance GO:0010033 153 0.060
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.060
Zebrafish
positive regulation of cell development GO:0010720 25 0.059
Fly
cardiogenic plate morphogenesis GO:0003142 1 0.059
negative regulation of protein kinase activity GO:0006469 4 0.059
hepaticobiliary system development GO:0061008 98 0.059
erythrocyte homeostasis GO:0034101 55 0.059
embryonic organ development GO:0048568 381 0.058
calcium mediated signaling GO:0019722 2 0.058
retinal cell programmed cell death GO:0046666 2 0.058
Zebrafish
hematopoietic stem cell differentiation GO:0060218 20 0.058
positive regulation of gene expression GO:0010628 71 0.057
mesenchymal cell differentiation GO:0048762 87 0.057
growth GO:0040007 174 0.057
myeloid cell differentiation GO:0030099 86 0.056
epiboly GO:0090504 41 0.056
neural crest cell differentiation GO:0014033 72 0.056
mesenchyme development GO:0060485 127 0.056
neuron remodeling GO:0016322 1 0.056
cell cell signaling GO:0007267 52 0.056
pectoral fin morphogenesis GO:0035138 29 0.055
otic vesicle development GO:0071599 42 0.054
negative regulation of nucleic acid templated transcription GO:1903507 45 0.054
Fly
gliogenesis GO:0042063 45 0.053
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.053
regulation of sequestering of calcium ion GO:0051282 4 0.053
ear development GO:0043583 127 0.052
positive regulation of endothelial cell differentiation GO:0045603 2 0.052
stem cell fate commitment GO:0048865 1 0.052
nucleocytoplasmic transport GO:0006913 4 0.052
sensory perception of light stimulus GO:0050953 19 0.052
Zebrafish
positive regulation of neurogenesis GO:0050769 24 0.051
Fly
entrainment of circadian clock GO:0009649 2 0.051
phototransduction GO:0007602 2 0.051
regulation of response to stimulus GO:0048583 269 0.051
negative regulation of secretion GO:0051048 2 0.050
tube morphogenesis GO:0035239 349 0.050
sensory perception of sound GO:0007605 9 0.049
mesoderm development GO:0007498 88 0.049
auditory receptor cell fate commitment GO:0009912 4 0.048
negative regulation of transcription dna templated GO:0045892 45 0.048
Fly
detection of light stimulus GO:0009583 12 0.048
axon regeneration GO:0031103 14 0.048
axon extension involved in axon guidance GO:0048846 10 0.048
negative regulation of cell differentiation GO:0045596 46 0.047
Zebrafish
stem cell differentiation GO:0048863 117 0.047
diencephalon development GO:0021536 58 0.047
neural crest cell migration GO:0001755 42 0.046
vitamin a metabolic process GO:0006776 1 0.046
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.045
regulation of response to external stimulus GO:0032101 31 0.045
forebrain neuron development GO:0021884 7 0.044
glial cell development GO:0021782 20 0.044
negative regulation of cellular biosynthetic process GO:0031327 55 0.044
Fly
embryonic hemopoiesis GO:0035162 53 0.044
adult behavior GO:0030534 2 0.044
somitogenesis GO:0001756 87 0.044
phosphate containing compound metabolic process GO:0006796 108 0.043
response to axon injury GO:0048678 14 0.043
cellular component assembly GO:0022607 170 0.043
embryonic pattern specification GO:0009880 44 0.043
negative regulation of signal transduction GO:0009968 94 0.043
regulation of cell projection organization GO:0031344 44 0.043
cell adhesion GO:0007155 40 0.042
morphogenesis of an epithelium GO:0002009 333 0.042
organelle organization GO:0006996 227 0.041
Fly
establishment or maintenance of cell polarity GO:0007163 29 0.040
regulation of developmental process GO:0050793 247 0.040
Zebrafish Fly
regulation of reproductive process GO:2000241 4 0.040
cellular response to endogenous stimulus GO:0071495 68 0.039
tissue homeostasis GO:0001894 25 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.038
Fly
detection of abiotic stimulus GO:0009582 24 0.038
cellular response to molecule of bacterial origin GO:0071219 3 0.038
positive regulation of transport GO:0051050 2 0.037
regulation of transport GO:0051049 45 0.037
lipid storage GO:0019915 1 0.037
anterior posterior pattern specification GO:0009952 152 0.037
Zebrafish
lamellipodium organization GO:0097581 1 0.037
morphogenesis of embryonic epithelium GO:0016331 30 0.037
establishment of localization in cell GO:0051649 77 0.037
carbohydrate homeostasis GO:0033500 1 0.036
protein localization GO:0008104 40 0.036
reflex GO:0060004 2 0.036
nuclear transport GO:0051169 4 0.036
apoptotic process GO:0006915 116 0.035
regulation of protein binding GO:0043393 3 0.035
alpha amino acid metabolic process GO:1901605 3 0.035
epithelial cell differentiation GO:0030855 116 0.035
embryonic heart tube formation GO:0003144 1 0.034
cytokinesis GO:0000910 3 0.034
circadian behavior GO:0048512 5 0.034
ion homeostasis GO:0050801 41 0.034
connective tissue development GO:0061448 99 0.034
mechanosensory lateral line system development GO:0048881 49 0.034
positive regulation of embryonic development GO:0040019 3 0.034
blood vessel morphogenesis GO:0048514 216 0.034
retinal pigment epithelium development GO:0003406 8 0.034
Zebrafish
lipid metabolic process GO:0006629 52 0.034
single organism cell adhesion GO:0098602 29 0.033
embryonic camera type eye morphogenesis GO:0048596 19 0.033
small molecule metabolic process GO:0044281 77 0.033
heart morphogenesis GO:0003007 156 0.033
limb bud formation GO:0060174 2 0.033
regulation of inflammatory response GO:0050727 2 0.033
hormone transport GO:0009914 2 0.033
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.033
response to endogenous stimulus GO:0009719 83 0.032
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.032
morphogenesis of an epithelial fold GO:0060571 1 0.032
spinal cord development GO:0021510 46 0.032
tissue regeneration GO:0042246 74 0.032
negative regulation of developmental process GO:0051093 65 0.032
Zebrafish
cellular ion homeostasis GO:0006873 17 0.032
positive regulation of cellular component movement GO:0051272 11 0.032
exocrine pancreas development GO:0031017 28 0.032
protein localization to nucleus GO:0034504 3 0.031
regulation of dendrite morphogenesis GO:0048814 3 0.031
regulation of cell fate specification GO:0042659 20 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.031
mechanoreceptor differentiation GO:0042490 37 0.031
photoreceptor cell fate specification GO:0043704 1 0.030
pancreas development GO:0031016 84 0.030
regulation of organ morphogenesis GO:2000027 35 0.030
Zebrafish Fly
bmp signaling pathway GO:0030509 52 0.030
determination of digestive tract left right asymmetry GO:0071907 10 0.030
rhombomere development GO:0021546 19 0.030
negative regulation of sequestering of calcium ion GO:0051283 4 0.030
regulation of endothelial cell differentiation GO:0045601 3 0.030
negative regulation of defense response GO:0031348 2 0.030
somite development GO:0061053 96 0.030
sequestering of metal ion GO:0051238 3 0.030
multicellular organismal response to stress GO:0033555 2 0.030
neurotransmitter transport GO:0006836 2 0.029
death GO:0016265 121 0.029
Zebrafish
cellular response to organic substance GO:0071310 105 0.029
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.029
cerebellum formation GO:0021588 2 0.029
nerve development GO:0021675 45 0.029
cytoskeleton organization GO:0007010 96 0.028
neuronal action potential GO:0019228 18 0.028
cellular response to stress GO:0033554 62 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.028
Fly
habenula development GO:0021986 9 0.028
organonitrogen compound metabolic process GO:1901564 74 0.027
response to uv GO:0009411 3 0.027
cellular component biogenesis GO:0044085 178 0.027
forebrain cell migration GO:0021885 1 0.027
rhombomere 5 development GO:0021571 4 0.027
regulation of locomotion GO:0040012 55 0.027
peripheral nervous system development GO:0007422 55 0.027
metencephalon development GO:0022037 27 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
neuron projection regeneration GO:0031102 16 0.027
rhodopsin mediated signaling pathway GO:0016056 1 0.027
specification of symmetry GO:0009799 204 0.026
rhombomere 6 development GO:0021572 4 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
otic placode formation GO:0043049 23 0.026
multicellular organism growth GO:0035264 4 0.026
ear morphogenesis GO:0042471 64 0.026
detection of stimulus involved in sensory perception GO:0050906 21 0.026
embryonic camera type eye development GO:0031076 29 0.026
negative regulation of mitosis GO:0045839 3 0.025
positive regulation of signaling GO:0023056 56 0.025
single organism transport GO:0044765 206 0.025
olfactory bulb development GO:0021772 4 0.025
vasculogenesis GO:0001570 41 0.025
central nervous system neuron differentiation GO:0021953 74 0.025
motor neuron axon guidance GO:0008045 23 0.025
single organism behavior GO:0044708 24 0.025
Worm
lymphatic endothelial cell fate commitment GO:0060838 1 0.025
positive regulation of neuron differentiation GO:0045666 12 0.025
Fly
intracellular receptor signaling pathway GO:0030522 30 0.025
ion transport GO:0006811 114 0.025
synaptic transmission GO:0007268 35 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.024
Fly
stem cell proliferation GO:0072089 4 0.024
odontogenesis of dentin containing tooth GO:0042475 1 0.024
fin regeneration GO:0031101 51 0.024
neuroblast proliferation GO:0007405 2 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.024
hormone secretion GO:0046879 2 0.024
myeloid cell homeostasis GO:0002262 56 0.024
axon ensheathment in central nervous system GO:0032291 2 0.024
cellular ketone metabolic process GO:0042180 11 0.024
morphogenesis of an epithelial sheet GO:0002011 49 0.023
response to vitamin GO:0033273 3 0.023
regulation of protein transport GO:0051223 3 0.023
mitotic cell cycle GO:0000278 64 0.023
actin cytoskeleton organization GO:0030036 63 0.022
cellular response to estrogen stimulus GO:0071391 24 0.022
multi organism process GO:0051704 134 0.022
kupffer s vesicle development GO:0070121 50 0.022
anterior lateral line nerve development GO:0048909 4 0.022
cellular lipid metabolic process GO:0044255 36 0.022
homeostasis of number of cells GO:0048872 62 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
inner ear receptor cell development GO:0060119 20 0.022
determination of bilateral symmetry GO:0009855 204 0.022
lateral line nerve development GO:0048892 9 0.022
cardiac cell fate commitment GO:0060911 1 0.021
regulation of cellular component size GO:0032535 30 0.021
mitotic cell cycle process GO:1903047 48 0.021
amine metabolic process GO:0009308 2 0.021
cell maturation GO:0048469 23 0.021
action potential GO:0001508 19 0.021
central nervous system neuron development GO:0021954 29 0.021
positive regulation of signal transduction GO:0009967 56 0.021
neural tube patterning GO:0021532 33 0.021
Zebrafish
regulation of embryonic development GO:0045995 47 0.021
circulatory system process GO:0003013 87 0.021
circadian sleep wake cycle GO:0042745 2 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
Zebrafish Worm Fly
single organism metabolic process GO:0044710 217 0.021
cellular calcium ion homeostasis GO:0006874 13 0.020
cellular response to hormone stimulus GO:0032870 39 0.020
gland morphogenesis GO:0022612 13 0.020
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
metal ion homeostasis GO:0055065 26 0.020
macromolecule localization GO:0033036 54 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
immune response GO:0006955 28 0.020
axial mesodermal cell fate specification GO:0048327 3 0.020
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
epithalamus development GO:0021538 10 0.020
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.020
protein import GO:0017038 3 0.020
cell cycle process GO:0022402 53 0.019
neuroblast differentiation GO:0014016 1 0.019
cell differentiation in spinal cord GO:0021515 40 0.019
positive regulation of neuron projection development GO:0010976 9 0.019
detection of external stimulus GO:0009581 24 0.019
regulation of cell morphogenesis GO:0022604 42 0.019
skeletal system development GO:0001501 181 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
Fly

otx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.580
Human
retinal disease DOID:5679 0 0.518
Human
retinal degeneration DOID:8466 0 0.518
Human
sensory system disease DOID:0050155 0 0.518
Human
eye and adnexa disease DOID:1492 0 0.518
Human
nervous system disease DOID:863 0 0.518
Human
eye disease DOID:5614 0 0.518
Human
retinitis pigmentosa DOID:10584 0 0.176
Human